Click here to switch to the map view.

The map label for this gene is 188586830

Identifier: 188586830

GI number: 188586830

Start: 2359384

End: 2360469

Strand: Direct

Name: 188586830

Synonym: Nther_2221

Alternate gene names: NA

Gene position: 2359384-2360469 (Clockwise)

Preceding gene: 188586810

Following gene: 188586849

Centisome position: 74.53

GC content: 48.9

Gene sequence:

>1086_bases
TTGTCTATAAAGAGCTGTAGTATTACGGAACTGACAGATTTTAAATTTGGTCATGCCCAAGATTTTCAGGCAGCCACGGG
TGTAACCGTAATTACCACTACAGAAGGTCAGGGAGTTACGGCCGGGGTAGATGTCAGGGGTAGCGCCCCGGGCACTAGAG
AAACAGATCTACTAGACCCCACTAACCTGGTGGAAGAAGTTCACGGCATTTTTCTTGCCGGAGGCAGTGCCTTTGGATTA
GAAGCAGCAGGTGGTATCATGAAGTACTTAGAAGAATCGGGTGTGGGTGTTCCCACAGGTTATGCCAAAGTTCCCATAGT
CCCAGGTGCAATTTTGTTTGACCTGGGAATCGGCGATCCCCGGACTCGTCCCGATGCCAATATGGGCTATCAGGCCGCAA
AAAATGCCGCCAACTCAAATCCCCAGGAAGGTAATTACGGCTGTGGAACGGGAGCCACTATCGGCAAGTTTGCCGGTGAA
GCCCATGCCATGAAAGCAGGGGTCGGCGTATCCGCCTTTAGAACGGGAGATTTGATCGTGGCTAGTTTGGTAGCAGTTAA
CTGCTTTGGTGAAGTTATAGACCCGGAAACCGGTCAGATAATAGGTGGAGCTTATGATAGCAGTACCTATCAGTTTATAA
GGGCCAGGGAAGTCCTGGGCCACGACAGTGAAAGTGATAAGGAAAACAGTAATAGTGCTGACAATGGTAAAGATCAAGGT
AATAGCCACGGTGACAGTGAACGCGATAGCGGCGGTTACAATGACGATAACGATGATGGTGAAAGAAGTATCTTCTCTCG
CAATAATACCACTATCGGAGTCGTTGTGACCAATGCCCAGCTAACTAAAGCAGCTGCTACCAAGGTAAGCCAAATGGCCC
ACAGCGGCATCTCCCGCACTACCAGACCCGCTCATTCCATGCTGGATGGTGACGCTTTATTTACCATGGCTTCCGGTCGT
GTAACTTCTGATTTGACTCTCATCGGTGAACTGGCCGCCCTGTCCGTGGAAAAATCTATCATTAATGGTGTAACCAAAGC
CCAGTCCAGCCATAATTTACCCGCTCACAATGATATATTTTTTTAG

Upstream 100 bases:

>100_bases
GCATAATCATCACAGATGCGACAGATATTCCCATGGCCACGTATCGACTCAATTATATTCTGATTACAACTGATCTCAAA
CTGAAGGAGGATTGATATAT

Downstream 100 bases:

>100_bases
ACATTAATGAAGGGGGCTAAAAGGCCCCCTTTAAATTTACTCTCTTTAGTTATGTCAATACTTGTTTATACTTCAGGTTC
TATCTGACCGTAATTTCCAT

Product: peptidase S58 DmpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSIKSCSITELTDFKFGHAQDFQAATGVTVITTTEGQGVTAGVDVRGSAPGTRETDLLDPTNLVEEVHGIFLAGGSAFGL
EAAGGIMKYLEESGVGVPTGYAKVPIVPGAILFDLGIGDPRTRPDANMGYQAAKNAANSNPQEGNYGCGTGATIGKFAGE
AHAMKAGVGVSAFRTGDLIVASLVAVNCFGEVIDPETGQIIGGAYDSSTYQFIRAREVLGHDSESDKENSNSADNGKDQG
NSHGDSERDSGGYNDDNDDGERSIFSRNNTTIGVVVTNAQLTKAAATKVSQMAHSGISRTTRPAHSMLDGDALFTMASGR
VTSDLTLIGELAALSVEKSIINGVTKAQSSHNLPAHNDIFF

Sequences:

>Translated_361_residues
MSIKSCSITELTDFKFGHAQDFQAATGVTVITTTEGQGVTAGVDVRGSAPGTRETDLLDPTNLVEEVHGIFLAGGSAFGL
EAAGGIMKYLEESGVGVPTGYAKVPIVPGAILFDLGIGDPRTRPDANMGYQAAKNAANSNPQEGNYGCGTGATIGKFAGE
AHAMKAGVGVSAFRTGDLIVASLVAVNCFGEVIDPETGQIIGGAYDSSTYQFIRAREVLGHDSESDKENSNSADNGKDQG
NSHGDSERDSGGYNDDNDDGERSIFSRNNTTIGVVVTNAQLTKAAATKVSQMAHSGISRTTRPAHSMLDGDALFTMASGR
VTSDLTLIGELAALSVEKSIINGVTKAQSSHNLPAHNDIFF
>Mature_360_residues
SIKSCSITELTDFKFGHAQDFQAATGVTVITTTEGQGVTAGVDVRGSAPGTRETDLLDPTNLVEEVHGIFLAGGSAFGLE
AAGGIMKYLEESGVGVPTGYAKVPIVPGAILFDLGIGDPRTRPDANMGYQAAKNAANSNPQEGNYGCGTGATIGKFAGEA
HAMKAGVGVSAFRTGDLIVASLVAVNCFGEVIDPETGQIIGGAYDSSTYQFIRAREVLGHDSESDKENSNSADNGKDQGN
SHGDSERDSGGYNDDNDDGERSIFSRNNTTIGVVVTNAQLTKAAATKVSQMAHSGISRTTRPAHSMLDGDALFTMASGRV
TSDLTLIGELAALSVEKSIINGVTKAQSSHNLPAHNDIFF

Specific function: Unknown

COG id: COG3191

COG function: function code EQ; L-aminopeptidase/D-esterase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1167 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016117
- InterPro:   IPR005321 [H]

Pfam domain/function: PF03576 Peptidase_S58 [H]

EC number: NA

Molecular weight: Translated: 37415; Mature: 37283

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKSCSITELTDFKFGHAQDFQAATGVTVITTTEGQGVTAGVDVRGSAPGTRETDLLDP
CCCCCCCCCEECCCCCCCCCCCHHHCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCH
TNLVEEVHGIFLAGGSAFGLEAAGGIMKYLEESGVGVPTGYAKVPIVPGAILFDLGIGDP
HHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCCEEEEEECCCCC
RTRPDANMGYQAAKNAANSNPQEGNYGCGTGATIGKFAGEAHAMKAGVGVSAFRTGDLIV
CCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCEEECCCHHHH
ASLVAVNCFGEVIDPETGQIIGGAYDSSTYQFIRAREVLGHDSESDKENSNSADNGKDQG
HHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
NSHGDSERDSGGYNDDNDDGERSIFSRNNTTIGVVVTNAQLTKAAATKVSQMAHSGISRT
CCCCCCCCCCCCCCCCCCCCHHHHEECCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCC
TRPAHSMLDGDALFTMASGRVTSDLTLIGELAALSVEKSIINGVTKAQSSHNLPAHNDIF
CCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
F
C
>Mature Secondary Structure 
SIKSCSITELTDFKFGHAQDFQAATGVTVITTTEGQGVTAGVDVRGSAPGTRETDLLDP
CCCCCCCCEECCCCCCCCCCCHHHCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCH
TNLVEEVHGIFLAGGSAFGLEAAGGIMKYLEESGVGVPTGYAKVPIVPGAILFDLGIGDP
HHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCCEEEEEECCCCC
RTRPDANMGYQAAKNAANSNPQEGNYGCGTGATIGKFAGEAHAMKAGVGVSAFRTGDLIV
CCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCEEECCCHHHH
ASLVAVNCFGEVIDPETGQIIGGAYDSSTYQFIRAREVLGHDSESDKENSNSADNGKDQG
HHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
NSHGDSERDSGGYNDDNDDGERSIFSRNNTTIGVVVTNAQLTKAAATKVSQMAHSGISRT
CCCCCCCCCCCCCCCCCCCCHHHHEECCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCC
TRPAHSMLDGDALFTMASGRVTSDLTLIGELAALSVEKSIINGVTKAQSSHNLPAHNDIF
CCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]