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The map label for this gene is yqiR [H]

Identifier: 188586790

GI number: 188586790

Start: 2307542

End: 2309326

Strand: Direct

Name: yqiR [H]

Synonym: Nther_2181

Alternate gene names: 188586790

Gene position: 2307542-2309326 (Clockwise)

Preceding gene: 188586789

Following gene: 188586792

Centisome position: 72.9

GC content: 36.69

Gene sequence:

>1785_bases
ATGGACTTTTCCAATCTGACAGTTTTAACAGCAGGGGATGCAGTCATTAAAGATATTTCTATTGTTTCACCTAGTGCCAC
AGTCAAAGAGTTAAATGAAATTATGCTGCTAAAGAAAAAAGAAGAAGTACTGGTGATGGAAAATCAAGCTATAGTCGGTG
TGATTACAAAAAACGATTTAGTAAAAAACTTAGCAACAGGAATAAAATGGGATACTGAAGTAAAATATATCATGACACGT
AATGTCATCCGCTTTAAAGACCACGAAGATTTAACTGGAGTTCGGGACAACATGCGATTTCACGGTATTAAAAGAGCTCC
TGTTTTAAATGAAAATGAGGAATGCCTTGGCTTGATAACTGTCAAATCTATCTGTGACGCATTTTCAAATAGACTGTGGC
ATGTGGTGGATTACCTGCAAATGGTTTTAAATAATCTCAATGAAGGTGTATTTATTCTCTCGAGTGATGGAGAAGTCCTT
TATCAAAATAATGCACTAGCCGGTATTCTAGCAACTCAGTCCGCTCAATCTACTCAGCCCGAGATTCCAAGGGAATTATT
ACAAAAAATCCAATCCGGAAGTGGAGGAGATTTCGTATACCATCTGAATAACAAAGTTTATTCAGTTAATGTAGCACCTT
TTCCATGTAATGAGTCCGAAGAAAATAAATTAGTCACAATCAAGAATGTTACTCACATAACGGAACTCCAAGAACAACTA
AGCCGAGCCAATAGTAAACTAAACTATCTGGAAAATACAGTCAGTAAAATTTCTCAAGAGCATTATACTTTTGGTAACAT
TTTTTCTGTTAGTCCAAAAATGGAACATGTAATTGAACTGGCAAAACAGGTAGCACCAACTAAAGCCACAGTCCTCATAA
ATGGTGAAAGCGGAACAGGAAAAGAATTACTGGCAAATGCCATTCATCAACACAGTGATAGAAAAGACGCTCCATTGATC
ACTATTAACTGCGGTGCTATCCCTGAAAATTTAGCTGAAAGTGAGTTCTTCGGATATTGTTCGGGGGCTTTCACAGGGGC
AAAAAAAGAAGGTAAACCAGGGGCTTTTGAAATAGCGGATGGAGGGACTTTATTTCTCGATGAAATAGGTGATCTCCCTC
TTAATATGCAAGCAAAATTACTAAGAGCACTACAAGAAGGTTCCTTTTACAGAGTAGGAGGGATAGAACCTGTCAGTGTC
GATGTCAGAATTATAGCAGCTACTAACCAAAACCTAGAAGAACTGGTTCAGAATAATCAGTTTAGAGAAGACTTATATTA
TCGAATCAATGTAGCGAATTTAGAACTTCCACCGCTAAGAGAAAAAACCGAAGACATTATGCCCCTAACTAAAAGATTTA
TAGATCATTTTTCCCAGGTTCACGGAATTGAGATTACAGAAATCGAACAAGCTGTTATGGATACTCTAGAGGAATATCAC
TGGCCCGGTAATGTAAGGGAATTAAAAAATGTAATAGAAAGACTTGTGATCTTTTCAACACAAGGCAAAATCAGTATCAA
AGCGCTCCCCTCTTATCTACATCCAGGGCCAAAATTTGGCAGTCAAGATCAACAACAGTTACATGAACAGCTACACAGAC
AGCATTCACAGGATGATAATTTCAGTAATAAAAGTAATTCAGAAAGTAAAATTGATGAGCTTGAACGAAAAACCATTCTT
GATTCCCTAAAGAAACATTCTTTCAACAAAGCTAAAGTTGCCCGTGAATTAAATATTCCCCGGAGTACACTTTATTATCG
CATGAAAGTTTTAAATATAAATTAA

Upstream 100 bases:

>100_bases
TTATGAATCTATTTACAGTTACGCTGAAAACGAGCATCAACATTAATGAGCATTAACATTAAATTGATCCGATTCACCAC
TTATAGAGGGGTGTATATTT

Downstream 100 bases:

>100_bases
TACTTTCAAAACCGCATAATTTGTTCACTACCGCATAATTTCACTACCGTATGATTTCACTACCGTATGATTTGTCTCAC
TGAAGATTTTACATTAATAG

Product: putative sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MDFSNLTVLTAGDAVIKDISIVSPSATVKELNEIMLLKKKEEVLVMENQAIVGVITKNDLVKNLATGIKWDTEVKYIMTR
NVIRFKDHEDLTGVRDNMRFHGIKRAPVLNENEECLGLITVKSICDAFSNRLWHVVDYLQMVLNNLNEGVFILSSDGEVL
YQNNALAGILATQSAQSTQPEIPRELLQKIQSGSGGDFVYHLNNKVYSVNVAPFPCNESEENKLVTIKNVTHITELQEQL
SRANSKLNYLENTVSKISQEHYTFGNIFSVSPKMEHVIELAKQVAPTKATVLINGESGTGKELLANAIHQHSDRKDAPLI
TINCGAIPENLAESEFFGYCSGAFTGAKKEGKPGAFEIADGGTLFLDEIGDLPLNMQAKLLRALQEGSFYRVGGIEPVSV
DVRIIAATNQNLEELVQNNQFREDLYYRINVANLELPPLREKTEDIMPLTKRFIDHFSQVHGIEITEIEQAVMDTLEEYH
WPGNVRELKNVIERLVIFSTQGKISIKALPSYLHPGPKFGSQDQQQLHEQLHRQHSQDDNFSNKSNSESKIDELERKTIL
DSLKKHSFNKAKVARELNIPRSTLYYRMKVLNIN

Sequences:

>Translated_594_residues
MDFSNLTVLTAGDAVIKDISIVSPSATVKELNEIMLLKKKEEVLVMENQAIVGVITKNDLVKNLATGIKWDTEVKYIMTR
NVIRFKDHEDLTGVRDNMRFHGIKRAPVLNENEECLGLITVKSICDAFSNRLWHVVDYLQMVLNNLNEGVFILSSDGEVL
YQNNALAGILATQSAQSTQPEIPRELLQKIQSGSGGDFVYHLNNKVYSVNVAPFPCNESEENKLVTIKNVTHITELQEQL
SRANSKLNYLENTVSKISQEHYTFGNIFSVSPKMEHVIELAKQVAPTKATVLINGESGTGKELLANAIHQHSDRKDAPLI
TINCGAIPENLAESEFFGYCSGAFTGAKKEGKPGAFEIADGGTLFLDEIGDLPLNMQAKLLRALQEGSFYRVGGIEPVSV
DVRIIAATNQNLEELVQNNQFREDLYYRINVANLELPPLREKTEDIMPLTKRFIDHFSQVHGIEITEIEQAVMDTLEEYH
WPGNVRELKNVIERLVIFSTQGKISIKALPSYLHPGPKFGSQDQQQLHEQLHRQHSQDDNFSNKSNSESKIDELERKTIL
DSLKKHSFNKAKVARELNIPRSTLYYRMKVLNIN
>Mature_594_residues
MDFSNLTVLTAGDAVIKDISIVSPSATVKELNEIMLLKKKEEVLVMENQAIVGVITKNDLVKNLATGIKWDTEVKYIMTR
NVIRFKDHEDLTGVRDNMRFHGIKRAPVLNENEECLGLITVKSICDAFSNRLWHVVDYLQMVLNNLNEGVFILSSDGEVL
YQNNALAGILATQSAQSTQPEIPRELLQKIQSGSGGDFVYHLNNKVYSVNVAPFPCNESEENKLVTIKNVTHITELQEQL
SRANSKLNYLENTVSKISQEHYTFGNIFSVSPKMEHVIELAKQVAPTKATVLINGESGTGKELLANAIHQHSDRKDAPLI
TINCGAIPENLAESEFFGYCSGAFTGAKKEGKPGAFEIADGGTLFLDEIGDLPLNMQAKLLRALQEGSFYRVGGIEPVSV
DVRIIAATNQNLEELVQNNQFREDLYYRINVANLELPPLREKTEDIMPLTKRFIDHFSQVHGIEITEIEQAVMDTLEEYH
WPGNVRELKNVIERLVIFSTQGKISIKALPSYLHPGPKFGSQDQQQLHEQLHRQHSQDDNFSNKSNSESKIDELERKTIL
DSLKKHSFNKAKVARELNIPRSTLYYRMKVLNIN

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=357, Percent_Identity=40.0560224089636, Blast_Score=265, Evalue=9e-72,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=44.2771084337349, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI87082117, Length=368, Percent_Identity=43.2065217391304, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI1790437, Length=355, Percent_Identity=41.6901408450704, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=43.2601880877743, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1786524, Length=341, Percent_Identity=41.6422287390029, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI1787583, Length=237, Percent_Identity=49.789029535865, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1789087, Length=255, Percent_Identity=47.843137254902, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1788905, Length=239, Percent_Identity=47.2803347280335, Blast_Score=222, Evalue=7e-59,
Organism=Escherichia coli, GI87082152, Length=336, Percent_Identity=37.5, Blast_Score=216, Evalue=5e-57,
Organism=Escherichia coli, GI87081872, Length=221, Percent_Identity=47.0588235294118, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI1789828, Length=277, Percent_Identity=35.7400722021661, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI87081858, Length=336, Percent_Identity=28.5714285714286, Blast_Score=152, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 66841; Mature: 66841

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSNLTVLTAGDAVIKDISIVSPSATVKELNEIMLLKKKEEVLVMENQAIVGVITKNDL
CCCCCEEEEECCCHHHHHCEECCCCHHHHHHHHHHHHCCCCCEEEEECCEEEEEEECHHH
VKNLATGIKWDTEVKYIMTRNVIRFKDHEDLTGVRDNMRFHGIKRAPVLNENEECLGLIT
HHHHHHCCCCCCCEEEEEECCEEEECCCCCCCCHHHCCCCCCEECCCCCCCCCCCEEEHH
VKSICDAFSNRLWHVVDYLQMVLNNLNEGVFILSSDGEVLYQNNALAGILATQSAQSTQP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCEEEEEEECCCCCCCC
EIPRELLQKIQSGSGGDFVYHLNNKVYSVNVAPFPCNESEENKLVTIKNVTHITELQEQL
HHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHH
SRANSKLNYLENTVSKISQEHYTFGNIFSVSPKMEHVIELAKQVAPTKATVLINGESGTG
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCC
KELLANAIHQHSDRKDAPLITINCGAIPENLAESEFFGYCSGAFTGAKKEGKPGAFEIAD
HHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECC
GGTLFLDEIGDLPLNMQAKLLRALQEGSFYRVGGIEPVSVDVRIIAATNQNLEELVQNNQ
CCEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEEEEEEEEECCCCHHHHHHCCC
FREDLYYRINVANLELPPLREKTEDIMPLTKRFIDHFSQVHGIEITEIEQAVMDTLEEYH
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
WPGNVRELKNVIERLVIFSTQGKISIKALPSYLHPGPKFGSQDQQQLHEQLHRQHSQDDN
CCCCHHHHHHHHHHHHEECCCCCEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC
FSNKSNSESKIDELERKTILDSLKKHSFNKAKVARELNIPRSTLYYRMKVLNIN
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHEEEEEEEEEECC
>Mature Secondary Structure
MDFSNLTVLTAGDAVIKDISIVSPSATVKELNEIMLLKKKEEVLVMENQAIVGVITKNDL
CCCCCEEEEECCCHHHHHCEECCCCHHHHHHHHHHHHCCCCCEEEEECCEEEEEEECHHH
VKNLATGIKWDTEVKYIMTRNVIRFKDHEDLTGVRDNMRFHGIKRAPVLNENEECLGLIT
HHHHHHCCCCCCCEEEEEECCEEEECCCCCCCCHHHCCCCCCEECCCCCCCCCCCEEEHH
VKSICDAFSNRLWHVVDYLQMVLNNLNEGVFILSSDGEVLYQNNALAGILATQSAQSTQP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCEEEEEEECCCCCCCC
EIPRELLQKIQSGSGGDFVYHLNNKVYSVNVAPFPCNESEENKLVTIKNVTHITELQEQL
HHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHH
SRANSKLNYLENTVSKISQEHYTFGNIFSVSPKMEHVIELAKQVAPTKATVLINGESGTG
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCC
KELLANAIHQHSDRKDAPLITINCGAIPENLAESEFFGYCSGAFTGAKKEGKPGAFEIAD
HHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECC
GGTLFLDEIGDLPLNMQAKLLRALQEGSFYRVGGIEPVSVDVRIIAATNQNLEELVQNNQ
CCEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEEEEEEEEECCCCHHHHHHCCC
FREDLYYRINVANLELPPLREKTEDIMPLTKRFIDHFSQVHGIEITEIEQAVMDTLEEYH
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
WPGNVRELKNVIERLVIFSTQGKISIKALPSYLHPGPKFGSQDQQQLHEQLHRQHSQDDN
CCCCHHHHHHHHHHHHEECCCCCEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC
FSNKSNSESKIDELERKTILDSLKKHSFNKAKVARELNIPRSTLYYRMKVLNIN
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]