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The map label for this gene is p20 [H]

Identifier: 188586785

GI number: 188586785

Start: 2300816

End: 2301424

Strand: Reverse

Name: p20 [H]

Synonym: Nther_2176

Alternate gene names: 188586785

Gene position: 2301424-2300816 (Counterclockwise)

Preceding gene: 188586786

Following gene: 188586784

Centisome position: 72.7

GC content: 31.69

Gene sequence:

>609_bases
ATGTTACAGAATTTAATTATAATAGCTTTATTTTGGAGTGTGATTAATATGAATTACTATAAAAAGTTAATTGGCACGAA
AGTCTATCTTTCACCTGTTAATCCCGAGGATTATGAAAAATATACCGAGTGGGTAAATGATCTGGAAATATCAATTAATT
TATCCTTTGCTTATAAGATTTTTTCAGAACAACAAGAAAAAGAAATGCTTCAGCAGATGAGTAAAGATGGTTATCAGTTT
GCCGTAGTTAAAAAAGATGCTGAGGAATTAATTGGCAATTGTGGATTGCACAATGTTGATTTGATAAATAGATCAGCTGA
GCTGGGAATTTTTATTGGTGATAAAAATTGTTGGGATGGTGGTTATGGAGTAGATGCCGTCAATTTATTGCTCGACTACG
CTTTTAATCTCCTTAATTTAAACAGTGTTTACTTGAGGGTTCATTCATTTAATGATAGAGCAATTCAATGTTATAAAAAG
TGTGGCTTTAAAGAAATCGGTAGAAGAAGAGAGGCCTACATCATCGGAGGTAATAAGTATGATGATGTTTACATGGATAT
ATTAGCCAGTGAATTTGAGTACGATAGCCAAATAATAAAATACATTTAG

Upstream 100 bases:

>100_bases
TGTTGTTGATACTGTAAGATTTTTAGTTATCAAGATTCTACTTTAATACAGCCTTGTAAAAAAACTATGATTAATTCTAA
TACCAGCAGGATTTCCCAAG

Downstream 100 bases:

>100_bases
AATTAAGTATAATTGTATTAAGTATAACTGTAAAAGGAGTGGTACTATTGAAGAAACTAGCTTTAATCTTTGCTTTACTA
GTATTTGTTCTAGGTATAGT

Product: GCN5-related N-acetyltransferase

Products: Coenzyme A; H+; N8-Acetylspermidine [C]

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MLQNLIIIALFWSVINMNYYKKLIGTKVYLSPVNPEDYEKYTEWVNDLEISINLSFAYKIFSEQQEKEMLQQMSKDGYQF
AVVKKDAEELIGNCGLHNVDLINRSAELGIFIGDKNCWDGGYGVDAVNLLLDYAFNLLNLNSVYLRVHSFNDRAIQCYKK
CGFKEIGRRREAYIIGGNKYDDVYMDILASEFEYDSQIIKYI

Sequences:

>Translated_202_residues
MLQNLIIIALFWSVINMNYYKKLIGTKVYLSPVNPEDYEKYTEWVNDLEISINLSFAYKIFSEQQEKEMLQQMSKDGYQF
AVVKKDAEELIGNCGLHNVDLINRSAELGIFIGDKNCWDGGYGVDAVNLLLDYAFNLLNLNSVYLRVHSFNDRAIQCYKK
CGFKEIGRRREAYIIGGNKYDDVYMDILASEFEYDSQIIKYI
>Mature_202_residues
MLQNLIIIALFWSVINMNYYKKLIGTKVYLSPVNPEDYEKYTEWVNDLEISINLSFAYKIFSEQQEKEMLQQMSKDGYQF
AVVKKDAEELIGNCGLHNVDLINRSAELGIFIGDKNCWDGGYGVDAVNLLLDYAFNLLNLNSVYLRVHSFNDRAIQCYKK
CGFKEIGRRREAYIIGGNKYDDVYMDILASEFEYDSQIIKYI

Specific function: Regulates Polyamine Concentration By Their Degradation. Acts On Spermidine, Forming N(1)- And N(8)-Acetylspermidine. [C]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: 2.3.1.57 [C]

Molecular weight: Translated: 23507; Mature: 23507

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQNLIIIALFWSVINMNYYKKLIGTKVYLSPVNPEDYEKYTEWVNDLEISINLSFAYKI
CCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCEEEEEEEEEHHHH
FSEQQEKEMLQQMSKDGYQFAVVKKDAEELIGNCGLHNVDLINRSAELGIFIGDKNCWDG
HHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHCCCCCCHHHCCCCCEEEEEECCCCCCCC
GYGVDAVNLLLDYAFNLLNLNSVYLRVHSFNDRAIQCYKKCGFKEIGRRREAYIIGGNKY
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCHHHHCCCCEEEEECCCCC
DDVYMDILASEFEYDSQIIKYI
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLQNLIIIALFWSVINMNYYKKLIGTKVYLSPVNPEDYEKYTEWVNDLEISINLSFAYKI
CCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCEEEEEEEEEHHHH
FSEQQEKEMLQQMSKDGYQFAVVKKDAEELIGNCGLHNVDLINRSAELGIFIGDKNCWDG
HHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHCCCCCCHHHCCCCCEEEEEECCCCCCCC
GYGVDAVNLLLDYAFNLLNLNSVYLRVHSFNDRAIQCYKKCGFKEIGRRREAYIIGGNKY
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCHHHHCCCCEEEEECCCCC
DDVYMDILASEFEYDSQIIKYI
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Spermidine [C]

Specific reaction: Acetyl-CoA + Spermidine --> Coenzyme A + H+ + N8-Acetylspermidine [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2838827 [H]