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The map label for this gene is lepB [H]

Identifier: 188586744

GI number: 188586744

Start: 2254626

End: 2255210

Strand: Reverse

Name: lepB [H]

Synonym: Nther_2135

Alternate gene names: 188586744

Gene position: 2255210-2254626 (Counterclockwise)

Preceding gene: 188586745

Following gene: 188586740

Centisome position: 71.24

GC content: 33.5

Gene sequence:

>585_bases
ATGCTCGGACTAATAAGCGAAATTTATCGTTGGATTAAACAAATAGTTTTCATATTAATAACCGTGATAATAATAAATAT
ATTTATTTTTCAAGTGTATGCTGTTAGAGGTTCATCAATGGAACCTACTTTCACTGATGGGGATAAAGTCATTGCATTTA
AAATCCCCTATCACTTGGATAATGAACCTGAATATCAGGATATAGTAGTCCTGGATAGTAGAGTTAATAGGGATAGAAAT
TGGATGGACGGCTTGATTGAAAGTCCCATAATAAGCAGAATACTAGATAATCAAGGAGATCACTTTTGGATTAAAAGAGT
GATTGGGATGCCAGGTGACAAAATAAAGTTTGAGAATGGTAGTATTTATAGGAATGGAGAGACATTGGAAGAACCAGAGA
TTTTAACAGGGGAAATCTATCCTTCAACTGATCCGCTGGTAGTTCCTGAAAATCATGTTTTTGTAATAGGTGATAATATA
AACCAAAGTAGAGACAGCAGACAAATTGGGCCTGTCCCTATGGATAATGTCAAAGGAAATGTACTCATGAGATATTATCC
TTTTGATGATTTAAAAATTTATTAA

Upstream 100 bases:

>100_bases
TTTGAGTAAGAATGGACAAGTTGAGAGAAAAGCGAAAAAAACATTTATTACTTTATCCTCTTAATAAGATTTTAAAATAT
CAATAAAGGAGACTTTGTGG

Downstream 100 bases:

>100_bases
TTGATACATCTTAATCATCTTTCCCTAATCATTTTTCTTTTGTTGTGAAATGAAATCCACTGCATTGAGTGCTGCAACCT
GGCCCTCTCCTACTGCTTTG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MLGLISEIYRWIKQIVFILITVIIINIFIFQVYAVRGSSMEPTFTDGDKVIAFKIPYHLDNEPEYQDIVVLDSRVNRDRN
WMDGLIESPIISRILDNQGDHFWIKRVIGMPGDKIKFENGSIYRNGETLEEPEILTGEIYPSTDPLVVPENHVFVIGDNI
NQSRDSRQIGPVPMDNVKGNVLMRYYPFDDLKIY

Sequences:

>Translated_194_residues
MLGLISEIYRWIKQIVFILITVIIINIFIFQVYAVRGSSMEPTFTDGDKVIAFKIPYHLDNEPEYQDIVVLDSRVNRDRN
WMDGLIESPIISRILDNQGDHFWIKRVIGMPGDKIKFENGSIYRNGETLEEPEILTGEIYPSTDPLVVPENHVFVIGDNI
NQSRDSRQIGPVPMDNVKGNVLMRYYPFDDLKIY
>Mature_194_residues
MLGLISEIYRWIKQIVFILITVIIINIFIFQVYAVRGSSMEPTFTDGDKVIAFKIPYHLDNEPEYQDIVVLDSRVNRDRN
WMDGLIESPIISRILDNQGDHFWIKRVIGMPGDKIKFENGSIYRNGETLEEPEILTGEIYPSTDPLVVPENHVFVIGDNI
NQSRDSRQIGPVPMDNVKGNVLMRYYPFDDLKIY

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 22480; Mature: 22480

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGLISEIYRWIKQIVFILITVIIINIFIFQVYAVRGSSMEPTFTDGDKVIAFKIPYHLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCEECC
NEPEYQDIVVLDSRVNRDRNWMDGLIESPIISRILDNQGDHFWIKRVIGMPGDKIKFENG
CCCCCCEEEEECCCCCCCCCHHHHHHCCHHHHHHHHCCCCEEEEHHHHCCCCCEEEECCC
SIYRNGETLEEPEILTGEIYPSTDPLVVPENHVFVIGDNINQSRDSRQIGPVPMDNVKGN
CEEECCCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC
VLMRYYPFDDLKIY
EEEEEECCCCEEEC
>Mature Secondary Structure
MLGLISEIYRWIKQIVFILITVIIINIFIFQVYAVRGSSMEPTFTDGDKVIAFKIPYHLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCEECC
NEPEYQDIVVLDSRVNRDRNWMDGLIESPIISRILDNQGDHFWIKRVIGMPGDKIKFENG
CCCCCCEEEEECCCCCCCCCHHHHHHCCHHHHHHHHCCCCEEEEHHHHCCCCCEEEECCC
SIYRNGETLEEPEILTGEIYPSTDPLVVPENHVFVIGDNINQSRDSRQIGPVPMDNVKGN
CEEECCCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC
VLMRYYPFDDLKIY
EEEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA