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The map label for this gene is aroF [H]

Identifier: 188586660

GI number: 188586660

Start: 2166408

End: 2167490

Strand: Direct

Name: aroF [H]

Synonym: Nther_2050

Alternate gene names: 188586660

Gene position: 2166408-2167490 (Clockwise)

Preceding gene: 188586659

Following gene: 188586661

Centisome position: 68.44

GC content: 37.21

Gene sequence:

>1083_bases
ATGATCATTGTAATGAATAGACAAACTCAAGAAGAAAAAATAAATAAAGTGATAAATAGACTCTCTGAATTGGAATTAGA
ATGTCATATATCTAAAGGCAAGAATAAAATTGTTATCGGAGTAATTGGAGAAAATAAACGCCATGCTTTAGAAGGTTTAG
AAGCTCTGCCATACGTTGAACAAATTGTACCCATAAGTAAACCATTTAAGCTTGTATCGCGAGAGTTTAAGGAAGATGAT
ACTCAAATAGCTTTTGGTGGAAAAAGTTCTCATGTAGTTAAAGATTCATCCCTATCAGGACCAGTAGTTGGTGGAAATAA
CTTCTCATTAATGGCTGGACCGTGTGCAATCGAAAATAAAGAAAACACTTTAGAAATAGCTCAACAAGTCAAGCAAACTG
GAGCCCAGTTCCTCAGAGGTGGCGCTTTTAAACCTAGAACTTCACCGTATAGTTTTCAAGGATTAGGAGCGGATGGCCTG
AAAATTATGTGGGAAGCCAGCCAGAAAACGGGTTTAAAAATAATCACAGAAGTTATGGACCCTCGACAGATTGAATTAGT
TAGTGATTATGCCCATGTTTTACAAATAGGCGCTAGAAATATGCAAAATTTTGAGTTATTAAAAGAGGCTGGAAACAGTA
ATCATCCTGTATTATTGAAGCGGGGTATGTCAGCTACAATAGAAGAGTGGTTGATGGCAGCCGAATACATTTTATCTAAA
GGAAACTATAAAGTAATGCTCTGTGAACGGGGTATAAGAACCTTTGAAACAGCTACTAGAAACACTCTAGATTTATCTGC
AGTAGCACTTGTCAAACAATTAAGCCATCTTCCTGTAATAGTTGACCCTAGTCACGGTACTGGAAAATGGAAGCTAGTGC
CAAGTATGAGTAAAGCAGCTTTAGCTGCAGGGGCAGATGGTTTAATTATTGAAGTTCATTCAACTCCTGAAACAGCCTTG
TCCGATGGTTCTCAGTCTCTTACTCCAGCTAATCTCGAAAAACTAACCAATCAACTAACAGAATTAGCACCTCACTTTGA
TAAAAGTTTTACTATTGGTTCCAAAACCGAGGAGCATATATAA

Upstream 100 bases:

>100_bases
CTTCCTTTGGAATGCCGGACCATTTTCGGATTACAATAGGTTCAAAATCAGATAATGAGTTTTTCATAGAAAAATTAAGT
AATTGCGAGGTGAATTTGAA

Downstream 100 bases:

>100_bases
TGAACAAAAACAATTTGCTGGTCATAGGCTTGGGATTAATGGCTGGGAGCCTGGCTCTTTCACTAAAAGAATGTGATTGT
TTTAATAAAATCACTGGATA

Product: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MIIVMNRQTQEEKINKVINRLSELELECHISKGKNKIVIGVIGENKRHALEGLEALPYVEQIVPISKPFKLVSREFKEDD
TQIAFGGKSSHVVKDSSLSGPVVGGNNFSLMAGPCAIENKENTLEIAQQVKQTGAQFLRGGAFKPRTSPYSFQGLGADGL
KIMWEASQKTGLKIITEVMDPRQIELVSDYAHVLQIGARNMQNFELLKEAGNSNHPVLLKRGMSATIEEWLMAAEYILSK
GNYKVMLCERGIRTFETATRNTLDLSAVALVKQLSHLPVIVDPSHGTGKWKLVPSMSKAALAAGADGLIIEVHSTPETAL
SDGSQSLTPANLEKLTNQLTELAPHFDKSFTIGSKTEEHI

Sequences:

>Translated_360_residues
MIIVMNRQTQEEKINKVINRLSELELECHISKGKNKIVIGVIGENKRHALEGLEALPYVEQIVPISKPFKLVSREFKEDD
TQIAFGGKSSHVVKDSSLSGPVVGGNNFSLMAGPCAIENKENTLEIAQQVKQTGAQFLRGGAFKPRTSPYSFQGLGADGL
KIMWEASQKTGLKIITEVMDPRQIELVSDYAHVLQIGARNMQNFELLKEAGNSNHPVLLKRGMSATIEEWLMAAEYILSK
GNYKVMLCERGIRTFETATRNTLDLSAVALVKQLSHLPVIVDPSHGTGKWKLVPSMSKAALAAGADGLIIEVHSTPETAL
SDGSQSLTPANLEKLTNQLTELAPHFDKSFTIGSKTEEHI
>Mature_360_residues
MIIVMNRQTQEEKINKVINRLSELELECHISKGKNKIVIGVIGENKRHALEGLEALPYVEQIVPISKPFKLVSREFKEDD
TQIAFGGKSSHVVKDSSLSGPVVGGNNFSLMAGPCAIENKENTLEIAQQVKQTGAQFLRGGAFKPRTSPYSFQGLGADGL
KIMWEASQKTGLKIITEVMDPRQIELVSDYAHVLQIGARNMQNFELLKEAGNSNHPVLLKRGMSATIEEWLMAAEYILSK
GNYKVMLCERGIRTFETATRNTLDLSAVALVKQLSHLPVIVDPSHGTGKWKLVPSMSKAALAAGADGLIIEVHSTPETAL
SDGSQSLTPANLEKLTNQLTELAPHFDKSFTIGSKTEEHI

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=254, Percent_Identity=26.7716535433071, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39440; Mature: 39440

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVMNRQTQEEKINKVINRLSELELECHISKGKNKIVIGVIGENKRHALEGLEALPYVE
CEEEECCCCHHHHHHHHHHHHHHCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHCCHHH
QIVPISKPFKLVSREFKEDDTQIAFGGKSSHVVKDSSLSGPVVGGNNFSLMAGPCAIENK
HHCCCCCHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCEECCCCCEEEECCEEECCC
ENTLEIAQQVKQTGAQFLRGGAFKPRTSPYSFQGLGADGLKIMWEASQKTGLKIITEVMD
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCC
PRQIELVSDYAHVLQIGARNMQNFELLKEAGNSNHPVLLKRGMSATIEEWLMAAEYILSK
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHCC
GNYKVMLCERGIRTFETATRNTLDLSAVALVKQLSHLPVIVDPSHGTGKWKLVPSMSKAA
CCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHHHH
LAAGADGLIIEVHSTPETALSDGSQSLTPANLEKLTNQLTELAPHFDKSFTIGSKTEEHI
HHCCCCCEEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCC
>Mature Secondary Structure
MIIVMNRQTQEEKINKVINRLSELELECHISKGKNKIVIGVIGENKRHALEGLEALPYVE
CEEEECCCCHHHHHHHHHHHHHHCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHCCHHH
QIVPISKPFKLVSREFKEDDTQIAFGGKSSHVVKDSSLSGPVVGGNNFSLMAGPCAIENK
HHCCCCCHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCEECCCCCEEEECCEEECCC
ENTLEIAQQVKQTGAQFLRGGAFKPRTSPYSFQGLGADGLKIMWEASQKTGLKIITEVMD
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCC
PRQIELVSDYAHVLQIGARNMQNFELLKEAGNSNHPVLLKRGMSATIEEWLMAAEYILSK
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHCC
GNYKVMLCERGIRTFETATRNTLDLSAVALVKQLSHLPVIVDPSHGTGKWKLVPSMSKAA
CCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHHHH
LAAGADGLIIEVHSTPETALSDGSQSLTPANLEKLTNQLTELAPHFDKSFTIGSKTEEHI
HHCCCCCEEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]