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The map label for this gene is pilC [H]

Identifier: 188586347

GI number: 188586347

Start: 1795755

End: 1796966

Strand: Reverse

Name: pilC [H]

Synonym: Nther_1730

Alternate gene names: 188586347

Gene position: 1796966-1795755 (Counterclockwise)

Preceding gene: 188586348

Following gene: 188586346

Centisome position: 56.77

GC content: 32.92

Gene sequence:

>1212_bases
ATGATTAAATATTATTATAGAGCAAAAAGTTGGACAGGAGAAGAAATTAAGGGATTTATCACTGCTGACAGTCGGGAAAC
AGCCATATTAAATTTAACAAATGAAAATTTTTGCTTAATTGAACTTAAAAATTATTCAAAGCGAGATTCGTTATTCGAAT
ATATCAGAAAATTTTTAGATCCAGTCACATCTAAAGAATTAATGCTATTTACTAGCCAATTTTCCACAATGGTTAGGTGT
GGGATTCCTGTTATTGAAAGTCTTGACTTGCAAACACAACAATTAGGAAATAAAAATCTGACCAGGGGACTAACCATAGT
AATAAAATCTCTAAACTCTGGTAAAAGTTTACGAGAAGCTTTTTCAGATGCCAGTGAAACCTTTCCATGGCTTATTACGG
AAATGGTGGGAGCTGGAGAAGAATCGGGACGCTTGGACGAAATTTTAGATCGTTTGGCATTACATTACGAACAGGAATAT
ACTTTATCTCAAAAACTAAAATCTGCTATTAGTTATCCAATTTTACTAATCATATTAGCTATGGTAGTAGTTTATATTTT
ATTAACAGTAATTTTCCCACAATTTATCAATTTGTTTGAAGCTCAGGGTGCAGAGTTACCTTTTATCACGAGAATGATTT
TTGATTCAGGGATTTGGATGACTGAAAACTTTTCACTTATCTTTGTCCTGGCTATCTTGTTAATGTTTTTGTGCGTTTAT
ATATTTCGAAGATTTGGAGCTCGGCTGATACTTGATTCTGTGAAATTAAAAATACCTGTTTTTGGTGATTTAGTTATAAA
AGCGAATGTTGCTCGTTTAACTAGAACTGCCGCAATGCTTTTGGAAAGTGGAGTCCCTCTGAAAAACTCCTTGAGTATTG
GAAAAAATGTTGTCAGTAATCTAAAAATACGAAGAGATATAGATAAAATTATTCACGGTATACAGGAAGGCCAGAGGATG
ACATATTGTATGTGTGGATTGGAAACTTTCCCAGATCTATGCAACAGATTGATATCTGTAGGAGAAGAAACAGGGACCCT
AGATGAAACATTGAAACGAATTGCTAATTTATACGAGAGGGAATTGAGTTTAAATGTCAAACAAATAACGGCTTTAATAG
AGCCATTAATGATATTAATTATGTCCTTAATAATCGGATTACTTGTCTTGGCTGTTATCATACCTGTTATTGAATTATGG
AAAATTTTCTAA

Upstream 100 bases:

>100_bases
GTGAATAATGCTTTACAGGATGTTAATAGTGGAATTACGACTTTAGAAGAAGTTATTAGAATAACAAGTTTCCAAGAATC
CCTAAAAGTGAGGAAATAAG

Downstream 100 bases:

>100_bases
AAAACTCAGATTAATTGAGGGGTAATGATATGAATTTGAGATCAAGTAATGAAATTACAACTTTAAAGAAATCTGGTTTT
ATTTTATTGGAATTATTGAT

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MIKYYYRAKSWTGEEIKGFITADSRETAILNLTNENFCLIELKNYSKRDSLFEYIRKFLDPVTSKELMLFTSQFSTMVRC
GIPVIESLDLQTQQLGNKNLTRGLTIVIKSLNSGKSLREAFSDASETFPWLITEMVGAGEESGRLDEILDRLALHYEQEY
TLSQKLKSAISYPILLIILAMVVVYILLTVIFPQFINLFEAQGAELPFITRMIFDSGIWMTENFSLIFVLAILLMFLCVY
IFRRFGARLILDSVKLKIPVFGDLVIKANVARLTRTAAMLLESGVPLKNSLSIGKNVVSNLKIRRDIDKIIHGIQEGQRM
TYCMCGLETFPDLCNRLISVGEETGTLDETLKRIANLYERELSLNVKQITALIEPLMILIMSLIIGLLVLAVIIPVIELW
KIF

Sequences:

>Translated_403_residues
MIKYYYRAKSWTGEEIKGFITADSRETAILNLTNENFCLIELKNYSKRDSLFEYIRKFLDPVTSKELMLFTSQFSTMVRC
GIPVIESLDLQTQQLGNKNLTRGLTIVIKSLNSGKSLREAFSDASETFPWLITEMVGAGEESGRLDEILDRLALHYEQEY
TLSQKLKSAISYPILLIILAMVVVYILLTVIFPQFINLFEAQGAELPFITRMIFDSGIWMTENFSLIFVLAILLMFLCVY
IFRRFGARLILDSVKLKIPVFGDLVIKANVARLTRTAAMLLESGVPLKNSLSIGKNVVSNLKIRRDIDKIIHGIQEGQRM
TYCMCGLETFPDLCNRLISVGEETGTLDETLKRIANLYERELSLNVKQITALIEPLMILIMSLIIGLLVLAVIIPVIELW
KIF
>Mature_403_residues
MIKYYYRAKSWTGEEIKGFITADSRETAILNLTNENFCLIELKNYSKRDSLFEYIRKFLDPVTSKELMLFTSQFSTMVRC
GIPVIESLDLQTQQLGNKNLTRGLTIVIKSLNSGKSLREAFSDASETFPWLITEMVGAGEESGRLDEILDRLALHYEQEY
TLSQKLKSAISYPILLIILAMVVVYILLTVIFPQFINLFEAQGAELPFITRMIFDSGIWMTENFSLIFVLAILLMFLCVY
IFRRFGARLILDSVKLKIPVFGDLVIKANVARLTRTAAMLLESGVPLKNSLSIGKNVVSNLKIRRDIDKIIHGIQEGQRM
TYCMCGLETFPDLCNRLISVGEETGTLDETLKRIANLYERELSLNVKQITALIEPLMILIMSLIIGLLVLAVIIPVIELW
KIF

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=399, Percent_Identity=27.5689223057644, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1786295, Length=396, Percent_Identity=24.2424242424242, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45842; Mature: 45842

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKYYYRAKSWTGEEIKGFITADSRETAILNLTNENFCLIELKNYSKRDSLFEYIRKFLD
CCEEEEECCCCCCHHHCEEEEECCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHC
PVTSKELMLFTSQFSTMVRCGIPVIESLDLQTQQLGNKNLTRGLTIVIKSLNSGKSLREA
CCCCHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
FSDASETFPWLITEMVGAGEESGRLDEILDRLALHYEQEYTLSQKLKSAISYPILLIILA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVVVYILLTVIFPQFINLFEAQGAELPFITRMIFDSGIWMTENFSLIFVLAILLMFLCVY
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHH
IFRRFGARLILDSVKLKIPVFGDLVIKANVARLTRTAAMLLESGVPLKNSLSIGKNVVSN
HHHHHCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LKIRRDIDKIIHGIQEGQRMTYCMCGLETFPDLCNRLISVGEETGTLDETLKRIANLYER
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ELSLNVKQITALIEPLMILIMSLIIGLLVLAVIIPVIELWKIF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKYYYRAKSWTGEEIKGFITADSRETAILNLTNENFCLIELKNYSKRDSLFEYIRKFLD
CCEEEEECCCCCCHHHCEEEEECCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHC
PVTSKELMLFTSQFSTMVRCGIPVIESLDLQTQQLGNKNLTRGLTIVIKSLNSGKSLREA
CCCCHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
FSDASETFPWLITEMVGAGEESGRLDEILDRLALHYEQEYTLSQKLKSAISYPILLIILA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVVVYILLTVIFPQFINLFEAQGAELPFITRMIFDSGIWMTENFSLIFVLAILLMFLCVY
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHH
IFRRFGARLILDSVKLKIPVFGDLVIKANVARLTRTAAMLLESGVPLKNSLSIGKNVVSN
HHHHHCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LKIRRDIDKIIHGIQEGQRMTYCMCGLETFPDLCNRLISVGEETGTLDETLKRIANLYER
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ELSLNVKQITALIEPLMILIMSLIIGLLVLAVIIPVIELWKIF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]