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The map label for this gene is ywaD [H]

Identifier: 188586158

GI number: 188586158

Start: 1616841

End: 1618556

Strand: Reverse

Name: ywaD [H]

Synonym: Nther_1537

Alternate gene names: 188586158

Gene position: 1618556-1616841 (Counterclockwise)

Preceding gene: 188586159

Following gene: 188586157

Centisome position: 51.13

GC content: 37.3

Gene sequence:

>1716_bases
ATGAGATTTACAGTCGAAAGTAGTCTCTCAATTACAAAATTATTTTTTATACTGTTAATCGCTGTATTAATAACAGTTAA
GTTAACAGGATGTGGTGATCACGGATATATGGTTTTTTTAAATTTAGAACCAGAAGAAGCCGGTGAAGTTTCAGGAAGTG
GAACTTATGAGCAAGGCGAAGAAATAACGGTATCAGTTGATACCGGAGAAAGTTGGGAGTTTATTGGATGGTTTGAAGAC
GGAGAAAAGGTTAGTAAAGAACAAGAATATACTTTTTCAGTAACAGAAAGTCGTAATTTAGTCGCTGAAATGAAACCAGG
GGAAGGGGAGGTTATCCAGGGATATATTGAAGATTTATTAGAGATAGGTCCTCGTCCACCTGGATCTGAAGCGGAAAAGG
AAGCAGCCCTATTCCTAAAGGATGTTTACCGTGATTTAGGATATGATGAAGAAGGATATGAACTGGAACTACAAGAGTTT
AAGTTAAGCGAGCAAACAGGGTTTGAAGATCTTAAAGGGCCAGAAAATATGAAACTAGCAGATATTTCTGTGATGGACGG
AGAAGAACATTTTGGAAATGTTTCAGCAGAATTAGCTGATCAAAGCTGGACTTATGAAAAATATCACGATACTGTTTGGC
AAGCAATGACTTCTCCCCATGGTGAAACAGCTTCTGTAGAAGGGGAAATGTATTATAGTGGAACTGGTATGGAAGAAGGT
GATTTCCCTGAAGAAGTTGATGGTAATATTGCTTTGATCAAAGTAGATGATACAGAAGTCGAATGGGAATTTAATGAAGA
TTTAAATCTGAGAACTTTCGAAATAAGTGAACAGCAAATCGAAAATGCAAAAGAGGCCGGAGCAGAGGCGGTTATTTTTA
CCTTCCTTGATGATGAACATCATCAAGGAAATACTGAAGCTCAAACTATGGTACCACTGATACAAGATAAAGAAGGAAAA
GAAAAGGAAGTGAATATACCTATCCTTGGAGCATCATCAATTCATGGTCAGTGGTTACAAGAAATGGAAAAAGAACATGC
AAATCCTCCAGAGTTAGAAATCAGCAGCTATAAAAATATTGATTTAAAGTCATATAATGTGGTGGCCACAAAGAAGTCAG
ATAAGGAAGATGCTCCGATTATCACAGTCACAGCCCATTTGGACAGTGTGCCTGGTTCTCCCGGCGCCAGTGATAATGCT
TCAGGAACTACCACTTTACTCAAACTGGCAGAATCATTAAAAAATAAAGACCTAGATGCAGAACTTCGCTTTGCTAATCT
GGGTGCTGAAGAAGTTGGTTTGTTTGGAGCATATCACTATGTTGAACAACTTTCTGAGGAAGAACTTGAAAATCATTATA
ATATTAATCCTGACATGATTGGAACCAGTTATCCGAAAAATGATGAATTGTTTATCACTTCCTTAGACCAAAGTGAAAAT
GAAGTGACCAATAGTTTACTTGAAGGACAGGAAATATTAGATTATGATGTAGCTACTTTTGATGCTCAGGTCAATATCAA
TTCTGATCATGTTGCCTTCGATGATAAAGGAATCCCAGCAGTATGCCTGGTATGGATGGGGGAACGAGGATTAGAACCAG
TTTATCACACTCCTTTAGATACTGTAGAAGATAATATTTCTGCCAAACGACTAAATTTGGCGTACGATATTATTAAAGAG
GGCATTATTCAACTTGATGAAAGAATACAGGATTAA

Upstream 100 bases:

>100_bases
AGTACCTAAAGATACGATTATACTAACTAAAGAGAAACTTAAAAAGTTAACAACTCTAAAAGCAACTGATAAAGAACTAT
TAATATCGGGGAGGATTATT

Downstream 100 bases:

>100_bases
ATTCATTATGTGGTCATTTGACAATAATATGATCATTCGTCGATCTTTTTCTAATCCTTTAACTTATTGAAAATATTCAT
AGGAAAGTAGAATCAAAGAT

Product: peptidase M28

Products: NA

Alternate protein names: Arginyl aminopeptidase; BSAP; Leucyl aminopeptidase [H]

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MRFTVESSLSITKLFFILLIAVLITVKLTGCGDHGYMVFLNLEPEEAGEVSGSGTYEQGEEITVSVDTGESWEFIGWFED
GEKVSKEQEYTFSVTESRNLVAEMKPGEGEVIQGYIEDLLEIGPRPPGSEAEKEAALFLKDVYRDLGYDEEGYELELQEF
KLSEQTGFEDLKGPENMKLADISVMDGEEHFGNVSAELADQSWTYEKYHDTVWQAMTSPHGETASVEGEMYYSGTGMEEG
DFPEEVDGNIALIKVDDTEVEWEFNEDLNLRTFEISEQQIENAKEAGAEAVIFTFLDDEHHQGNTEAQTMVPLIQDKEGK
EKEVNIPILGASSIHGQWLQEMEKEHANPPELEISSYKNIDLKSYNVVATKKSDKEDAPIITVTAHLDSVPGSPGASDNA
SGTTTLLKLAESLKNKDLDAELRFANLGAEEVGLFGAYHYVEQLSEEELENHYNINPDMIGTSYPKNDELFITSLDQSEN
EVTNSLLEGQEILDYDVATFDAQVNINSDHVAFDDKGIPAVCLVWMGERGLEPVYHTPLDTVEDNISAKRLNLAYDIIKE
GIIQLDERIQD

Sequences:

>Translated_571_residues
MRFTVESSLSITKLFFILLIAVLITVKLTGCGDHGYMVFLNLEPEEAGEVSGSGTYEQGEEITVSVDTGESWEFIGWFED
GEKVSKEQEYTFSVTESRNLVAEMKPGEGEVIQGYIEDLLEIGPRPPGSEAEKEAALFLKDVYRDLGYDEEGYELELQEF
KLSEQTGFEDLKGPENMKLADISVMDGEEHFGNVSAELADQSWTYEKYHDTVWQAMTSPHGETASVEGEMYYSGTGMEEG
DFPEEVDGNIALIKVDDTEVEWEFNEDLNLRTFEISEQQIENAKEAGAEAVIFTFLDDEHHQGNTEAQTMVPLIQDKEGK
EKEVNIPILGASSIHGQWLQEMEKEHANPPELEISSYKNIDLKSYNVVATKKSDKEDAPIITVTAHLDSVPGSPGASDNA
SGTTTLLKLAESLKNKDLDAELRFANLGAEEVGLFGAYHYVEQLSEEELENHYNINPDMIGTSYPKNDELFITSLDQSEN
EVTNSLLEGQEILDYDVATFDAQVNINSDHVAFDDKGIPAVCLVWMGERGLEPVYHTPLDTVEDNISAKRLNLAYDIIKE
GIIQLDERIQD
>Mature_571_residues
MRFTVESSLSITKLFFILLIAVLITVKLTGCGDHGYMVFLNLEPEEAGEVSGSGTYEQGEEITVSVDTGESWEFIGWFED
GEKVSKEQEYTFSVTESRNLVAEMKPGEGEVIQGYIEDLLEIGPRPPGSEAEKEAALFLKDVYRDLGYDEEGYELELQEF
KLSEQTGFEDLKGPENMKLADISVMDGEEHFGNVSAELADQSWTYEKYHDTVWQAMTSPHGETASVEGEMYYSGTGMEEG
DFPEEVDGNIALIKVDDTEVEWEFNEDLNLRTFEISEQQIENAKEAGAEAVIFTFLDDEHHQGNTEAQTMVPLIQDKEGK
EKEVNIPILGASSIHGQWLQEMEKEHANPPELEISSYKNIDLKSYNVVATKKSDKEDAPIITVTAHLDSVPGSPGASDNA
SGTTTLLKLAESLKNKDLDAELRFANLGAEEVGLFGAYHYVEQLSEEELENHYNINPDMIGTSYPKNDELFITSLDQSEN
EVTNSLLEGQEILDYDVATFDAQVNINSDHVAFDDKGIPAVCLVWMGERGLEPVYHTPLDTVEDNISAKRLNLAYDIIKE
GIIQLDERIQD

Specific function: Catalyzes the hydrolysis of a range of N-terminal amino acids [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28B subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319763, Length=199, Percent_Identity=31.1557788944724, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007484
- InterPro:   IPR003137 [H]

Pfam domain/function: PF02225 PA; PF04389 Peptidase_M28 [H]

EC number: =3.4.11.6; =3.4.11.10 [H]

Molecular weight: Translated: 63767; Mature: 63767

Theoretical pI: Translated: 3.89; Mature: 3.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTVESSLSITKLFFILLIAVLITVKLTGCGDHGYMVFLNLEPEEAGEVSGSGTYEQGE
CEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEECCHHHCCCCCCCCCCCCC
EITVSVDTGESWEFIGWFEDGEKVSKEQEYTFSVTESRNLVAEMKPGEGEVIQGYIEDLL
EEEEEEECCCCEEEEEEECCCHHHCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHH
EIGPRPPGSEAEKEAALFLKDVYRDLGYDEEGYELELQEFKLSEQTGFEDLKGPENMKLA
HCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHEECCHHCCCHHCCCCCCCEEE
DISVMDGEEHFGNVSAELADQSWTYEKYHDTVWQAMTSPHGETASVEGEMYYSGTGMEEG
EEEEECCHHHHCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEECCCCCCC
DFPEEVDGNIALIKVDDTEVEWEFNEDLNLRTFEISEQQIENAKEAGAEAVIFTFLDDEH
CCCHHCCCCEEEEEEECCEEEEEECCCCCEEEEECCHHHHHHHHHCCCCEEEEEEECCCC
HQGNTEAQTMVPLIQDKEGKEKEVNIPILGASSIHGQWLQEMEKEHANPPELEISSYKNI
CCCCCCHHHEEHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCC
DLKSYNVVATKKSDKEDAPIITVTAHLDSVPGSPGASDNASGTTTLLKLAESLKNKDLDA
CCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
ELRFANLGAEEVGLFGAYHYVEQLSEEELENHYNINPDMIGTSYPKNDELFITSLDQSEN
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHH
EVTNSLLEGQEILDYDVATFDAQVNINSDHVAFDDKGIPAVCLVWMGERGLEPVYHTPLD
HHHHHHHCCCHHHCCCEEEEEEEEECCCCEEEECCCCCCEEEEEEECCCCCCCCCCCCCH
TVEDNISAKRLNLAYDIIKEGIIQLDERIQD
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFTVESSLSITKLFFILLIAVLITVKLTGCGDHGYMVFLNLEPEEAGEVSGSGTYEQGE
CEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEECCHHHCCCCCCCCCCCCC
EITVSVDTGESWEFIGWFEDGEKVSKEQEYTFSVTESRNLVAEMKPGEGEVIQGYIEDLL
EEEEEEECCCCEEEEEEECCCHHHCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHH
EIGPRPPGSEAEKEAALFLKDVYRDLGYDEEGYELELQEFKLSEQTGFEDLKGPENMKLA
HCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHEECCHHCCCHHCCCCCCCEEE
DISVMDGEEHFGNVSAELADQSWTYEKYHDTVWQAMTSPHGETASVEGEMYYSGTGMEEG
EEEEECCHHHHCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEECCCCCCC
DFPEEVDGNIALIKVDDTEVEWEFNEDLNLRTFEISEQQIENAKEAGAEAVIFTFLDDEH
CCCHHCCCCEEEEEEECCEEEEEECCCCCEEEEECCHHHHHHHHHCCCCEEEEEEECCCC
HQGNTEAQTMVPLIQDKEGKEKEVNIPILGASSIHGQWLQEMEKEHANPPELEISSYKNI
CCCCCCHHHEEHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCC
DLKSYNVVATKKSDKEDAPIITVTAHLDSVPGSPGASDNASGTTTLLKLAESLKNKDLDA
CCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
ELRFANLGAEEVGLFGAYHYVEQLSEEELENHYNINPDMIGTSYPKNDELFITSLDQSEN
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHH
EVTNSLLEGQEILDYDVATFDAQVNINSDHVAFDDKGIPAVCLVWMGERGLEPVYHTPLD
HHHHHHHCCCHHHCCCEEEEEEEEECCCCEEEECCCCCCEEEEEEECCCCCCCCCCCCCH
TVEDNISAKRLNLAYDIIKEGIIQLDERIQD
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 1806041 [H]