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The map label for this gene is xerD [H]

Identifier: 188586142

GI number: 188586142

Start: 1595622

End: 1596461

Strand: Direct

Name: xerD [H]

Synonym: Nther_1519

Alternate gene names: 188586142

Gene position: 1595622-1596461 (Clockwise)

Preceding gene: 188586141

Following gene: 188586155

Centisome position: 50.41

GC content: 30.24

Gene sequence:

>840_bases
ATGATAAAAGAGAAGCTACTTAAGGACTTTATTGAAAATTCCAGTAATCAGCACTCAGCCTCAACACTAGAAACATATGA
GCGTTATATAAGAAAATTTTTAATGTCTTGGAAAAATGACCTATCGGAAGTTACCGACGATGATATTGATGATTTTCTTA
ATGAGTATGAAGAAAAAGGATATAACTCACGAACTATACACGTTATCATTGCAGCGTTACATGATTTTTTCTCCCATTTA
AAATATAAGAAATATATTAGTGTAATTCCAACGGTAGATGTTGAAATACCAAACCATGAAAAAAAATTACCAAAGCCTTT
AAGCGAAATAAAAATTATAAAGTTAAAAAATGAAGCAAAAGACCATCTACGAGATAGAGCTATTATAGAAGTTTTACATT
GGACAGGAGTGCGTGTAAGTGAACTAATAAACATTAGAATTGAAGATATTTGGTGGGATACAAGAGAAATTTGGATTAGA
AAAGGCAAAGGTCTTAAAGAAAGAAATGTAATAATTAACTATATATGTAAACAGTATCTTATAGAATATCTAGATACAAG
AAGCGACGACATACCATATTTATTTATAACCAAGAGAAAAAGACCTTTTACTCGCCAAGGTGTTAATAAGCTACTGAATA
AATATGCAATTAAAGCTGGCATTAAAGAAAATGTGACACCACATATGTTTAGACATACTTTTATCACAGACTTAATTAAT
AAAGGAGCTGAAGAAGGAGTTGTAGCAGATCTTGCTGGACATGAAGATATAAAACGGTTAAAAGATTATACAGAAGTAGC
TCGTAAAAGGAAAAAACTAGAATATGAAAAACTCCATTAA

Upstream 100 bases:

>100_bases
AGACCACGATGACCCTAATACAACAAGAATTTACGGGAAATCTTCATCAAGAAAAAAGCGAGAAGAATATGACAAATATA
TGACATAGGAGGATAATGAT

Downstream 100 bases:

>100_bases
AAAATTATGTTATAAAAGTTGGAGAACCTCAGATAAAAAATGTTATGTAAACTTAAAGGATGTGAGGTAAATTGCCTTGC
ATCCTTTAATTATGGGTTCG

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MIKEKLLKDFIENSSNQHSASTLETYERYIRKFLMSWKNDLSEVTDDDIDDFLNEYEEKGYNSRTIHVIIAALHDFFSHL
KYKKYISVIPTVDVEIPNHEKKLPKPLSEIKIIKLKNEAKDHLRDRAIIEVLHWTGVRVSELINIRIEDIWWDTREIWIR
KGKGLKERNVIINYICKQYLIEYLDTRSDDIPYLFITKRKRPFTRQGVNKLLNKYAIKAGIKENVTPHMFRHTFITDLIN
KGAEEGVVADLAGHEDIKRLKDYTEVARKRKKLEYEKLH

Sequences:

>Translated_279_residues
MIKEKLLKDFIENSSNQHSASTLETYERYIRKFLMSWKNDLSEVTDDDIDDFLNEYEEKGYNSRTIHVIIAALHDFFSHL
KYKKYISVIPTVDVEIPNHEKKLPKPLSEIKIIKLKNEAKDHLRDRAIIEVLHWTGVRVSELINIRIEDIWWDTREIWIR
KGKGLKERNVIINYICKQYLIEYLDTRSDDIPYLFITKRKRPFTRQGVNKLLNKYAIKAGIKENVTPHMFRHTFITDLIN
KGAEEGVVADLAGHEDIKRLKDYTEVARKRKKLEYEKLH
>Mature_279_residues
MIKEKLLKDFIENSSNQHSASTLETYERYIRKFLMSWKNDLSEVTDDDIDDFLNEYEEKGYNSRTIHVIIAALHDFFSHL
KYKKYISVIPTVDVEIPNHEKKLPKPLSEIKIIKLKNEAKDHLRDRAIIEVLHWTGVRVSELINIRIEDIWWDTREIWIR
KGKGLKERNVIINYICKQYLIEYLDTRSDDIPYLFITKRKRPFTRQGVNKLLNKYAIKAGIKENVTPHMFRHTFITDLIN
KGAEEGVVADLAGHEDIKRLKDYTEVARKRKKLEYEKLH

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=275, Percent_Identity=32.3636363636364, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790244, Length=274, Percent_Identity=27.3722627737226, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33227; Mature: 33227

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKEKLLKDFIENSSNQHSASTLETYERYIRKFLMSWKNDLSEVTDDDIDDFLNEYEEKG
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
YNSRTIHVIIAALHDFFSHLKYKKYISVIPTVDVEIPNHEKKLPKPLSEIKIIKLKNEAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHCCCCHHHEEEEEEHHHHH
DHLRDRAIIEVLHWTGVRVSELINIRIEDIWWDTREIWIRKGKGLKERNVIINYICKQYL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IEYLDTRSDDIPYLFITKRKRPFTRQGVNKLLNKYAIKAGIKENVTPHMFRHTFITDLIN
HHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
KGAEEGVVADLAGHEDIKRLKDYTEVARKRKKLEYEKLH
CCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure
MIKEKLLKDFIENSSNQHSASTLETYERYIRKFLMSWKNDLSEVTDDDIDDFLNEYEEKG
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
YNSRTIHVIIAALHDFFSHLKYKKYISVIPTVDVEIPNHEKKLPKPLSEIKIIKLKNEAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHCCCCHHHEEEEEEHHHHH
DHLRDRAIIEVLHWTGVRVSELINIRIEDIWWDTREIWIRKGKGLKERNVIINYICKQYL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IEYLDTRSDDIPYLFITKRKRPFTRQGVNKLLNKYAIKAGIKENVTPHMFRHTFITDLIN
HHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
KGAEEGVVADLAGHEDIKRLKDYTEVARKRKKLEYEKLH
CCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]