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The map label for this gene is hfq

Identifier: 188586125

GI number: 188586125

Start: 1573521

End: 1573775

Strand: Direct

Name: hfq

Synonym: Nther_1499

Alternate gene names: 188586125

Gene position: 1573521-1573775 (Clockwise)

Preceding gene: 188586124

Following gene: 188586126

Centisome position: 49.71

GC content: 32.16

Gene sequence:

>255_bases
TTGTCAAAAAACACAATTAATTTACAGGATAATGTTTTAAACCAGGTGAGGAAGAACAAAATTACAGTAACTATTTTTTT
GGTCAATGGCTATAAAATTCGCGGCCTAATTAAAAGTTTCGATAATTTCACACTATTGATGGAGGTTAATGGTGAACAAC
AGATGATTTATAAGCATGCAGTTAGTACCATAATCCCAGGTAAAACTCTCAATCTCTTCTCCGATCAATCCGATAAAAAT
GATCAAGAACAGTAA

Upstream 100 bases:

>100_bases
TTATTGATATGATCTTGAAGGAATATTTGGAATAACATAGAAATATAGATATTAGGTAATAAAAATTATATAATATATAA
ATTATATTGGAGGCGATAGC

Downstream 100 bases:

>100_bases
TTGACGTGTATTGTAATTATTTAAAAATGACTTGGAATCAACTTGAAATCATAATGTATTTTTAATTTTAGTTATTATGA
ATTTATTTACTCGTGATTTG

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 84; Mature: 83

Protein sequence:

>84_residues
MSKNTINLQDNVLNQVRKNKITVTIFLVNGYKIRGLIKSFDNFTLLMEVNGEQQMIYKHAVSTIIPGKTLNLFSDQSDKN
DQEQ

Sequences:

>Translated_84_residues
MSKNTINLQDNVLNQVRKNKITVTIFLVNGYKIRGLIKSFDNFTLLMEVNGEQQMIYKHAVSTIIPGKTLNLFSDQSDKN
DQEQ
>Mature_83_residues
SKNTINLQDNVLNQVRKNKITVTIFLVNGYKIRGLIKSFDNFTLLMEVNGEQQMIYKHAVSTIIPGKTLNLFSDQSDKND
QEQ

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=69, Percent_Identity=44.9275362318841, Blast_Score=72, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_NATTJ (B2A3Y0)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001917670.1
- ProteinModelPortal:   B2A3Y0
- SMR:   B2A3Y0
- GeneID:   6314835
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_1499
- HOGENOM:   HBG645207
- OMA:   KNTINIQ
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9646; Mature: 9515

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNTINLQDNVLNQVRKNKITVTIFLVNGYKIRGLIKSFDNFTLLMEVNGEQQMIYKHA
CCCCEECCHHHHHHHHHCCCEEEEEEEECCEEEEEHHCCCCCEEEEEEECCCHHHHHHHH
VSTIIPGKTLNLFSDQSDKNDQEQ
HHHHCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SKNTINLQDNVLNQVRKNKITVTIFLVNGYKIRGLIKSFDNFTLLMEVNGEQQMIYKHA
CCCEECCHHHHHHHHHCCCEEEEEEEECCEEEEEHHCCCCCEEEEEEECCCHHHHHHHH
VSTIIPGKTLNLFSDQSDKNDQEQ
HHHHCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA