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The map label for this gene is pgsA [H]

Identifier: 188586094

GI number: 188586094

Start: 1540522

End: 1541076

Strand: Direct

Name: pgsA [H]

Synonym: Nther_1468

Alternate gene names: 188586094

Gene position: 1540522-1541076 (Clockwise)

Preceding gene: 188586093

Following gene: 188586095

Centisome position: 48.67

GC content: 35.86

Gene sequence:

>555_bases
ATGAATTTAGCTAATAAGATAACAATAGCAAGAATCATACTGGCACCTGTTTTTATGGTGTTTTTACTGGTTACAGTTCC
ATATGGAGAATTAATAGCGTGGGCCATATTTATCTTGGCATCTATTACTGATGCCCTAGATGGGTATATTGCCAGAAGCA
GAAAACAGATAACGAAATTCGGTAAATTTCTTGACCCTCTAGCGGATAAGCTATTAATTACGGCTGCTTTAATTACATTG
GTAGGTTTAGGTAGATTACATTCGGCTGTAGCAGTAATTATAATCAGTAGAGAGTTTGCCGTTACTGGTTTACGTGTTAT
TGCTGCTGGTGAAGGAATGGTTATCTCGGCTAGTAAACTTGGAAAATTAAAAACTATCACCCAGGTGATAGCTATTTCTG
CGATTATGTTACAGGCTGGATTTGAAGATTTGGTTGCTATGGATGTATCTATTGATTTTTTAGTTGACTTATCTGTTTGG
GTAGCAGTAGTTGTCACTATTCTATCTGGAATTGACTATTTTAATAAAAATCGCCACTTAATTCGATTAGGGTAA

Upstream 100 bases:

>100_bases
GGAGCTGTTATAATACCCGATTGTGAAGCTTCATCTGGAGATTTTATAAATGTTGAGATAGTTCAAGCTTTAGATTACGA
TTTAATTGGAGAAATGACAA

Downstream 100 bases:

>100_bases
ATAATTAAACATAAAATTTCTAACTTAGATCAGTAAGGATCTGGTCAGGTTCAGCATAATTAAATTATTGGGAATTTGAG
ACAGGTATTACTTACCTGTC

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNLANKITIARIILAPVFMVFLLVTVPYGELIAWAIFILASITDALDGYIARSRKQITKFGKFLDPLADKLLITAALITL
VGLGRLHSAVAVIIISREFAVTGLRVIAAGEGMVISASKLGKLKTITQVIAISAIMLQAGFEDLVAMDVSIDFLVDLSVW
VAVVVTILSGIDYFNKNRHLIRLG

Sequences:

>Translated_184_residues
MNLANKITIARIILAPVFMVFLLVTVPYGELIAWAIFILASITDALDGYIARSRKQITKFGKFLDPLADKLLITAALITL
VGLGRLHSAVAVIIISREFAVTGLRVIAAGEGMVISASKLGKLKTITQVIAISAIMLQAGFEDLVAMDVSIDFLVDLSVW
VAVVVTILSGIDYFNKNRHLIRLG
>Mature_184_residues
MNLANKITIARIILAPVFMVFLLVTVPYGELIAWAIFILASITDALDGYIARSRKQITKFGKFLDPLADKLLITAALITL
VGLGRLHSAVAVIIISREFAVTGLRVIAAGEGMVISASKLGKLKTITQVIAISAIMLQAGFEDLVAMDVSIDFLVDLSVW
VAVVVTILSGIDYFNKNRHLIRLG

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=183, Percent_Identity=30.0546448087432, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 19894; Mature: 19894

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLANKITIARIILAPVFMVFLLVTVPYGELIAWAIFILASITDALDGYIARSRKQITKF
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKFLDPLADKLLITAALITLVGLGRLHSAVAVIIISREFAVTGLRVIAAGEGMVISASKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHEEEECCCEEEEHHHH
GKLKTITQVIAISAIMLQAGFEDLVAMDVSIDFLVDLSVWVAVVVTILSGIDYFNKNRHL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IRLG
EEEC
>Mature Secondary Structure
MNLANKITIARIILAPVFMVFLLVTVPYGELIAWAIFILASITDALDGYIARSRKQITKF
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKFLDPLADKLLITAALITLVGLGRLHSAVAVIIISREFAVTGLRVIAAGEGMVISASKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHEEEECCCEEEEHHHH
GKLKTITQVIAISAIMLQAGFEDLVAMDVSIDFLVDLSVWVAVVVTILSGIDYFNKNRHL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IRLG
EEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]