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The map label for this gene is flhA [H]

Identifier: 188586039

GI number: 188586039

Start: 1481718

End: 1483778

Strand: Direct

Name: flhA [H]

Synonym: Nther_1413

Alternate gene names: 188586039

Gene position: 1481718-1483778 (Clockwise)

Preceding gene: 188586038

Following gene: 188586040

Centisome position: 46.81

GC content: 38.48

Gene sequence:

>2061_bases
ATGCGTCATGTTGACTTGATAGTTGTTCTTGCAGTCATAGCAATAGTATTAATGTTAATTTTACCAGTTCCGCCGGAACT
GTTAGATTTTTTGCTGGTGTTGAATATAACAGTAGCTCTAACTATATTACTGATATCTATGTATACTTTAGAACCTCTGC
AATTCTCTATATTTCCGACTCTGTTGCTGTTAGTTACTATATACCGTTTGGCTCTTAATGTTTCATCAACTCGTCTGATC
CTATTGGATGCTTACGCAGGAGAAGTTATAATGCAATTTGGAGAATTTGTCGTAGGTGGTAACCCTATTGTAGGTTTTGT
TATTTTCCTAATTTTAATATCAATCCAATTTATTGTTATTACCAAGGGGGCCGAACGGGTTTCAGAAGTAACTGCTCGTT
TCACTTTGGATGCCATGCCTGGTAAACAAATGGCTATTGATGCTGATCTAAATTCGGGTTTAATAGATGAACAGCAGGCT
AAAGAGAGGCGTGAAGCTGTAGAACAAGAAGCTGATTTTTACGGTGCCATGGATGGTGCCAGTAAATTTGTTAAAGGGGA
CGCTATTGCAGGAATAGTCATCACTATAATAAATATATTAGGTGGATTTGTCATTGGAATGGCTCAACAGGGCATGACAT
TTCAAGAAGCCCTGCAAACCTTCACTTTATTGACAGTTGGTGATGGCTTGGTGACCCAGATACCTGCTTTACTGGTGTCT
ACTTCCACAGGTATTGTAGTTACGCGAGCTGCTTCAGATTCTAACTTGGGTCAAGATGTTGTCAGACAAATACTTGCACA
TCCCAAAGTTTTATTTATAGTTGGTGGTGTCTTAGCGGCTGTGGGGGCATTTCCCGGTATGCCGCCTTTACCATTTTTAG
CACTAGGTTCTATTATGGGCTTTTTAGGTTTTCAACTACGTACTTCTTTAAAATCAGAAGAACCTACTCCGGAAGAAGAA
CAAGCTGCTGCTACTGAAGAGGAAGCTGAAGAATATCGAAGTCCAGAGAATGTTATGTCTTTATTAAAAATAGACCCAAT
TGAATTTGAATTCGGATATGGATTACTTCCCTTGGCTGACCCCGATCAAGGAGGGGATTTACTAGACCGGGTTACTATGA
TTAGAAGACAAGTAGCCATGGAACTAGGTATCGTAGTTCCTGTGATCAGAGTGCGGGACAATATTCAACTGTCTTCCAAT
GAGTACTGCATAAAAATTAAAGGAGTAGAAGTGGCCAAGGAAGAAGTACTACCAAATCATTACTTAGTGATGATTCCGGG
AGATTCAAGTGGAAAACCAGAGGACCTGGGTTTAGAAGGAACAGAAACTAAAGAACCAGTATTTGGTCTCCCTGCCTTAT
GGATAGACGAAAGCCAGCGTGAACAAGCTGAAATGTCGGGATATACTGTAGTTGATCCTCCCTCGGTGTTAGCAACTCAT
TTAACAGAGATTATAAAACAGCATGCCCATGAGTTACTTGGAAGACAGGAAACTAAAGAATTAATAGACAATGTTAAAAA
TGATTATCCAGCGGTAGTAGAGGAATTGGTTGACAATATCTTGAACATTGGAGAAATACGCAAGGTATTGGCAAATCTGT
TAAAAGAGGGTGTATCAATCAAAAACTTATTAACTATTTTGGAAACTTTAACTGATTACGGAGCAGTTACCAAGGATACT
GATATGTTAACAGAGTATGTTAGGCAAAATCTCAACCGGGAAATAACCACTAAATTAAAAGAACTGCAAGGTGAGCCAAT
AAAAGTGATTACTTTAAGTCCAGAATTAGAACAAAAAATATCCGATTCCATCAAACAAACAGATCATGGGAACTATTTAT
CTATTGAACCACAGGTGACTCAAAAAATACAAAAACAACTGAAGAATTACACAGAACAACTTACCCAACAGGGTTTACAG
CCAATAGTGGTTACTTCACCCATGGTGAGATTGTATTTTAAACGGTTAACAGAAGGTTTTTTACCAAATCTGATGGTGGT
ATCTTTTCATGAATTAGATCCTCAAATTGAAGCACAATCTGTTGGGGTGGTGAATACATAA

Upstream 100 bases:

>100_bases
TTGGGGACTTTATTCCAGAAGAGTTATATCAAGCAGTTGCGGAAGTACTAGCCTTTGTCTATAGGTTAAAAAAATCATCA
GGCATGGAGTGATCATAATT

Downstream 100 bases:

>100_bases
ATGAAAGTCAAAAAATACTTGGCCAATAGTGAAAAAGAAGCACTAGAACAAATTAAAGCAGAAATGGGAAATAATGCTAT
AATTCTAAATACCCGGAGAG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MRHVDLIVVLAVIAIVLMLILPVPPELLDFLLVLNITVALTILLISMYTLEPLQFSIFPTLLLLVTIYRLALNVSSTRLI
LLDAYAGEVIMQFGEFVVGGNPIVGFVIFLILISIQFIVITKGAERVSEVTARFTLDAMPGKQMAIDADLNSGLIDEQQA
KERREAVEQEADFYGAMDGASKFVKGDAIAGIVITIINILGGFVIGMAQQGMTFQEALQTFTLLTVGDGLVTQIPALLVS
TSTGIVVTRAASDSNLGQDVVRQILAHPKVLFIVGGVLAAVGAFPGMPPLPFLALGSIMGFLGFQLRTSLKSEEPTPEEE
QAAATEEEAEEYRSPENVMSLLKIDPIEFEFGYGLLPLADPDQGGDLLDRVTMIRRQVAMELGIVVPVIRVRDNIQLSSN
EYCIKIKGVEVAKEEVLPNHYLVMIPGDSSGKPEDLGLEGTETKEPVFGLPALWIDESQREQAEMSGYTVVDPPSVLATH
LTEIIKQHAHELLGRQETKELIDNVKNDYPAVVEELVDNILNIGEIRKVLANLLKEGVSIKNLLTILETLTDYGAVTKDT
DMLTEYVRQNLNREITTKLKELQGEPIKVITLSPELEQKISDSIKQTDHGNYLSIEPQVTQKIQKQLKNYTEQLTQQGLQ
PIVVTSPMVRLYFKRLTEGFLPNLMVVSFHELDPQIEAQSVGVVNT

Sequences:

>Translated_686_residues
MRHVDLIVVLAVIAIVLMLILPVPPELLDFLLVLNITVALTILLISMYTLEPLQFSIFPTLLLLVTIYRLALNVSSTRLI
LLDAYAGEVIMQFGEFVVGGNPIVGFVIFLILISIQFIVITKGAERVSEVTARFTLDAMPGKQMAIDADLNSGLIDEQQA
KERREAVEQEADFYGAMDGASKFVKGDAIAGIVITIINILGGFVIGMAQQGMTFQEALQTFTLLTVGDGLVTQIPALLVS
TSTGIVVTRAASDSNLGQDVVRQILAHPKVLFIVGGVLAAVGAFPGMPPLPFLALGSIMGFLGFQLRTSLKSEEPTPEEE
QAAATEEEAEEYRSPENVMSLLKIDPIEFEFGYGLLPLADPDQGGDLLDRVTMIRRQVAMELGIVVPVIRVRDNIQLSSN
EYCIKIKGVEVAKEEVLPNHYLVMIPGDSSGKPEDLGLEGTETKEPVFGLPALWIDESQREQAEMSGYTVVDPPSVLATH
LTEIIKQHAHELLGRQETKELIDNVKNDYPAVVEELVDNILNIGEIRKVLANLLKEGVSIKNLLTILETLTDYGAVTKDT
DMLTEYVRQNLNREITTKLKELQGEPIKVITLSPELEQKISDSIKQTDHGNYLSIEPQVTQKIQKQLKNYTEQLTQQGLQ
PIVVTSPMVRLYFKRLTEGFLPNLMVVSFHELDPQIEAQSVGVVNT
>Mature_686_residues
MRHVDLIVVLAVIAIVLMLILPVPPELLDFLLVLNITVALTILLISMYTLEPLQFSIFPTLLLLVTIYRLALNVSSTRLI
LLDAYAGEVIMQFGEFVVGGNPIVGFVIFLILISIQFIVITKGAERVSEVTARFTLDAMPGKQMAIDADLNSGLIDEQQA
KERREAVEQEADFYGAMDGASKFVKGDAIAGIVITIINILGGFVIGMAQQGMTFQEALQTFTLLTVGDGLVTQIPALLVS
TSTGIVVTRAASDSNLGQDVVRQILAHPKVLFIVGGVLAAVGAFPGMPPLPFLALGSIMGFLGFQLRTSLKSEEPTPEEE
QAAATEEEAEEYRSPENVMSLLKIDPIEFEFGYGLLPLADPDQGGDLLDRVTMIRRQVAMELGIVVPVIRVRDNIQLSSN
EYCIKIKGVEVAKEEVLPNHYLVMIPGDSSGKPEDLGLEGTETKEPVFGLPALWIDESQREQAEMSGYTVVDPPSVLATH
LTEIIKQHAHELLGRQETKELIDNVKNDYPAVVEELVDNILNIGEIRKVLANLLKEGVSIKNLLTILETLTDYGAVTKDT
DMLTEYVRQNLNREITTKLKELQGEPIKVITLSPELEQKISDSIKQTDHGNYLSIEPQVTQKIQKQLKNYTEQLTQQGLQ
PIVVTSPMVRLYFKRLTEGFLPNLMVVSFHELDPQIEAQSVGVVNT

Specific function: Involved in the export of flagellum proteins [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=667, Percent_Identity=42.1289355322339, Blast_Score=513, Evalue=1e-146,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75461; Mature: 75461

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS00187 TPP_ENZYMES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHVDLIVVLAVIAIVLMLILPVPPELLDFLLVLNITVALTILLISMYTLEPLQFSIFPT
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LLLLVTIYRLALNVSSTRLILLDAYAGEVIMQFGEFVVGGNPIVGFVIFLILISIQFIVI
HHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEE
TKGAERVSEVTARFTLDAMPGKQMAIDADLNSGLIDEQQAKERREAVEQEADFYGAMDGA
ECCHHHHHHHHHHHEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHH
SKFVKGDAIAGIVITIINILGGFVIGMAQQGMTFQEALQTFTLLTVGDGLVTQIPALLVS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHC
TSTGIVVTRAASDSNLGQDVVRQILAHPKVLFIVGGVLAAVGAFPGMPPLPFLALGSIMG
CCCCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FLGFQLRTSLKSEEPTPEEEQAAATEEEAEEYRSPENVMSLLKIDPIEFEFGYGLLPLAD
HHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCCC
PDQGGDLLDRVTMIRRQVAMELGIVVPVIRVRDNIQLSSNEYCIKIKGVEVAKEEVLPNH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCHHHHHHCCCCC
YLVMIPGDSSGKPEDLGLEGTETKEPVFGLPALWIDESQREQAEMSGYTVVDPPSVLATH
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCHHHHHHH
LTEIIKQHAHELLGRQETKELIDNVKNDYPAVVEELVDNILNIGEIRKVLANLLKEGVSI
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCH
KNLLTILETLTDYGAVTKDTDMLTEYVRQNLNREITTKLKELQGEPIKVITLSPELEQKI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECHHHHHHH
SDSIKQTDHGNYLSIEPQVTQKIQKQLKNYTEQLTQQGLQPIVVTSPMVRLYFKRLTEGF
HHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHC
LPNLMVVSFHELDPQIEAQSVGVVNT
CCCEEEEEHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRHVDLIVVLAVIAIVLMLILPVPPELLDFLLVLNITVALTILLISMYTLEPLQFSIFPT
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LLLLVTIYRLALNVSSTRLILLDAYAGEVIMQFGEFVVGGNPIVGFVIFLILISIQFIVI
HHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEE
TKGAERVSEVTARFTLDAMPGKQMAIDADLNSGLIDEQQAKERREAVEQEADFYGAMDGA
ECCHHHHHHHHHHHEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHH
SKFVKGDAIAGIVITIINILGGFVIGMAQQGMTFQEALQTFTLLTVGDGLVTQIPALLVS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHC
TSTGIVVTRAASDSNLGQDVVRQILAHPKVLFIVGGVLAAVGAFPGMPPLPFLALGSIMG
CCCCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FLGFQLRTSLKSEEPTPEEEQAAATEEEAEEYRSPENVMSLLKIDPIEFEFGYGLLPLAD
HHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCCC
PDQGGDLLDRVTMIRRQVAMELGIVVPVIRVRDNIQLSSNEYCIKIKGVEVAKEEVLPNH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCHHHHHHCCCCC
YLVMIPGDSSGKPEDLGLEGTETKEPVFGLPALWIDESQREQAEMSGYTVVDPPSVLATH
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCHHHHHHH
LTEIIKQHAHELLGRQETKELIDNVKNDYPAVVEELVDNILNIGEIRKVLANLLKEGVSI
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCH
KNLLTILETLTDYGAVTKDTDMLTEYVRQNLNREITTKLKELQGEPIKVITLSPELEQKI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECHHHHHHH
SDSIKQTDHGNYLSIEPQVTQKIQKQLKNYTEQLTQQGLQPIVVTSPMVRLYFKRLTEGF
HHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHC
LPNLMVVSFHELDPQIEAQSVGVVNT
CCCEEEEEHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8097015; 9384377 [H]