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The map label for this gene is fliI [H]

Identifier: 188586020

GI number: 188586020

Start: 1466044

End: 1467363

Strand: Direct

Name: fliI [H]

Synonym: Nther_1394

Alternate gene names: 188586020

Gene position: 1466044-1467363 (Clockwise)

Preceding gene: 188586019

Following gene: 188586021

Centisome position: 46.31

GC content: 42.88

Gene sequence:

>1320_bases
GTGGCAACTGATGGTGTAGACTTAGATAAACTTTCTCAAACAATAAGGAATAGTAACACTTTACCTTTACAAGGAGAAGT
CACCAGAGTTGTAGGGTTAACTGTTGAGGCCCGAGGCCCAGGGGCTAAAATCGGTGATTTGTGCCTTATCAGAAGTGATG
ATCAGGAGATTGAGTGTGAAGTTGTAGGTTTCAATGATGGAAAAATACTATTGATGCCCCTTGGTAATTTAAACAATGTG
GCACCGGGTAATAAAGTGATTACTTCTCGAGAGAATTTGTCAGTACCTGTAGGTCCTGGTTTGGTTGGTAGAGTATTAGA
TGGTCTAGGTCGCCCTATGGATGGAAAGGGCCCCCTTACTAATACAAAATGTCGTTATCCTATGGAAAACACTCCCCCCG
CTCCCCTTGACCGCAGTAGGATACAAAAACCTATTCAAACTGGTATTAAAGCTATTGATGGGGTTTTGACAATTGGAAAA
GGGCAGCGGATGGGAATTTTTTCAGGGTCTGGAGTAGGTAAAAGTACACTCCTAGGTATGATTGCAAGAAATACTTCTGC
CTCTGTCAATGTAATTGGTTTAATAGGTGAACGGGGCAGAGAAGTTCGTGAATTTATAGAAAAAGATTTAGGAGAAGAAG
GATTACAACGAAGTGTTATTGTGGTTGCCACCTCTGACCAACCCGCTCTTTTGAGAATCAAGGGAGCGATGACTGCAACT
GCTATTGCAGAATATTTCCGTGACTGTGGAAATGATGTCATGCTAATGATGGACTCTGTAACCAGGTTTGCTACTGCCAA
ACGGGAAGTTGGACTGGCAACAGGTGAGCCACCGGCTACAAGAGGGTTTCCACCTTCTGTTTTTGCAATGTTGCCCCAGC
TGTTAGAAAGGTCTGGTACTTCTGATAAAGGGAGTGTTACCGGTTTATATACTGTATTGGTTGATGGAGATGATATGGAC
GAGCCCGTATCCGATACCGTTCGGGGAGTGCTAGATGGTCATATTGTTCTTAGCAGAAAGCTGGCCATGCAAAATCATTA
TCCGGCCATTGATATACTACAGAGCATTTCACGGGTGATGGTGGATATTACTGATACTCAACATCAAAAAGCGGCTGCCA
AAATTAGTTCAGCTCTGGCAGCCTATGAAGAGGCCCGAGATTTGATTGAAATCGGGGCTTATAAAAAGGGGAGCAATCCC
AAGGTTGACTGGGCGATGGAGCTAATTGACGATTTAAATGAGTTTTTACGCCAGGAAATCACAGAAAAAACTACTCTGGA
TGAAACCATCAATAAACTAAAGAAGTTTTTAGATGATTAA

Upstream 100 bases:

>100_bases
CCAGGAGCACCAATTTTGTTTGGGGAAAATGGACATATTGAACTAGAACTAAGTCGGCAAATAGATGAACTTCGCCGAGC
CTTGGGGCAGGTGATTAACA

Downstream 100 bases:

>100_bases
TTGGTTGACTAAATGTAGGGAAAGACAGAGGTGGTAATATTGAAGAAGTTCCAATTCTCTTTGGAGAAGGTATTAAAAGT
TAAGGAACGCAATGAAGAAC

Product: type III secretion system ATPase, FliI/YscN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MATDGVDLDKLSQTIRNSNTLPLQGEVTRVVGLTVEARGPGAKIGDLCLIRSDDQEIECEVVGFNDGKILLMPLGNLNNV
APGNKVITSRENLSVPVGPGLVGRVLDGLGRPMDGKGPLTNTKCRYPMENTPPAPLDRSRIQKPIQTGIKAIDGVLTIGK
GQRMGIFSGSGVGKSTLLGMIARNTSASVNVIGLIGERGREVREFIEKDLGEEGLQRSVIVVATSDQPALLRIKGAMTAT
AIAEYFRDCGNDVMLMMDSVTRFATAKREVGLATGEPPATRGFPPSVFAMLPQLLERSGTSDKGSVTGLYTVLVDGDDMD
EPVSDTVRGVLDGHIVLSRKLAMQNHYPAIDILQSISRVMVDITDTQHQKAAAKISSALAAYEEARDLIEIGAYKKGSNP
KVDWAMELIDDLNEFLRQEITEKTTLDETINKLKKFLDD

Sequences:

>Translated_439_residues
MATDGVDLDKLSQTIRNSNTLPLQGEVTRVVGLTVEARGPGAKIGDLCLIRSDDQEIECEVVGFNDGKILLMPLGNLNNV
APGNKVITSRENLSVPVGPGLVGRVLDGLGRPMDGKGPLTNTKCRYPMENTPPAPLDRSRIQKPIQTGIKAIDGVLTIGK
GQRMGIFSGSGVGKSTLLGMIARNTSASVNVIGLIGERGREVREFIEKDLGEEGLQRSVIVVATSDQPALLRIKGAMTAT
AIAEYFRDCGNDVMLMMDSVTRFATAKREVGLATGEPPATRGFPPSVFAMLPQLLERSGTSDKGSVTGLYTVLVDGDDMD
EPVSDTVRGVLDGHIVLSRKLAMQNHYPAIDILQSISRVMVDITDTQHQKAAAKISSALAAYEEARDLIEIGAYKKGSNP
KVDWAMELIDDLNEFLRQEITEKTTLDETINKLKKFLDD
>Mature_438_residues
ATDGVDLDKLSQTIRNSNTLPLQGEVTRVVGLTVEARGPGAKIGDLCLIRSDDQEIECEVVGFNDGKILLMPLGNLNNVA
PGNKVITSRENLSVPVGPGLVGRVLDGLGRPMDGKGPLTNTKCRYPMENTPPAPLDRSRIQKPIQTGIKAIDGVLTIGKG
QRMGIFSGSGVGKSTLLGMIARNTSASVNVIGLIGERGREVREFIEKDLGEEGLQRSVIVVATSDQPALLRIKGAMTATA
IAEYFRDCGNDVMLMMDSVTRFATAKREVGLATGEPPATRGFPPSVFAMLPQLLERSGTSDKGSVTGLYTVLVDGDDMDE
PVSDTVRGVLDGHIVLSRKLAMQNHYPAIDILQSISRVMVDITDTQHQKAAAKISSALAAYEEARDLIEIGAYKKGSNPK
VDWAMELIDDLNEFLRQEITEKTTLDETINKLKKFLDD

Specific function: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum [H]

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=320, Percent_Identity=33.4375, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI50345984, Length=334, Percent_Identity=28.1437125748503, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI4757810, Length=334, Percent_Identity=28.1437125748503, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI19913428, Length=315, Percent_Identity=29.5238095238095, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI19913426, Length=285, Percent_Identity=29.4736842105263, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI19913424, Length=268, Percent_Identity=28.7313432835821, Blast_Score=108, Evalue=7e-24,
Organism=Escherichia coli, GI1788251, Length=426, Percent_Identity=48.8262910798122, Blast_Score=387, Evalue=1e-109,
Organism=Escherichia coli, GI1790170, Length=375, Percent_Identity=29.6, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1790172, Length=336, Percent_Identity=32.1428571428571, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1790217, Length=215, Percent_Identity=30.2325581395349, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25144756, Length=321, Percent_Identity=32.398753894081, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI71988080, Length=334, Percent_Identity=28.1437125748503, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71988063, Length=334, Percent_Identity=28.1437125748503, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17510931, Length=280, Percent_Identity=29.6428571428571, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17570191, Length=283, Percent_Identity=29.3286219081272, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71988074, Length=299, Percent_Identity=26.7558528428094, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17565854, Length=279, Percent_Identity=29.3906810035842, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322581, Length=388, Percent_Identity=30.9278350515464, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6319370, Length=341, Percent_Identity=31.0850439882698, Blast_Score=159, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6319603, Length=291, Percent_Identity=29.553264604811, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320016, Length=184, Percent_Identity=32.6086956521739, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24638766, Length=320, Percent_Identity=32.1875, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28574560, Length=320, Percent_Identity=32.5, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24658560, Length=334, Percent_Identity=30.5389221556886, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI281361666, Length=363, Percent_Identity=26.9972451790634, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646341, Length=363, Percent_Identity=26.9972451790634, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17136796, Length=363, Percent_Identity=26.9972451790634, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI20129479, Length=289, Percent_Identity=28.719723183391, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24583988, Length=239, Percent_Identity=30.1255230125523, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583986, Length=239, Percent_Identity=30.1255230125523, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583984, Length=239, Percent_Identity=30.1255230125523, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583992, Length=234, Percent_Identity=30.3418803418803, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000225
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR004100
- InterPro:   IPR005714
- InterPro:   IPR022425 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 47315; Mature: 47184

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDGVDLDKLSQTIRNSNTLPLQGEVTRVVGLTVEARGPGAKIGDLCLIRSDDQEIECE
CCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCCCEEEEECCCCCEEEE
VVGFNDGKILLMPLGNLNNVAPGNKVITSRENLSVPVGPGLVGRVLDGLGRPMDGKGPLT
EEEECCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
NTKCRYPMENTPPAPLDRSRIQKPIQTGIKAIDGVLTIGKGQRMGIFSGSGVGKSTLLGM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCEEEEECCCCCCHHHHHHH
IARNTSASVNVIGLIGERGREVREFIEKDLGEEGLQRSVIVVATSDQPALLRIKGAMTAT
HHCCCCCCEEEEEEECCCCHHHHHHHHHHHCHHCCCCCEEEEEECCCCEEEEEECHHHHH
AIAEYFRDCGNDVMLMMDSVTRFATAKREVGLATGEPPATRGFPPSVFAMLPQLLERSGT
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
SDKGSVTGLYTVLVDGDDMDEPVSDTVRGVLDGHIVLSRKLAMQNHYPAIDILQSISRVM
CCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
VDITDTQHQKAAAKISSALAAYEEARDLIEIGAYKKGSNPKVDWAMELIDDLNEFLRQEI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TEKTTLDETINKLKKFLDD
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATDGVDLDKLSQTIRNSNTLPLQGEVTRVVGLTVEARGPGAKIGDLCLIRSDDQEIECE
CCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCCCCEEEEECCCCCEEEE
VVGFNDGKILLMPLGNLNNVAPGNKVITSRENLSVPVGPGLVGRVLDGLGRPMDGKGPLT
EEEECCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
NTKCRYPMENTPPAPLDRSRIQKPIQTGIKAIDGVLTIGKGQRMGIFSGSGVGKSTLLGM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCEEEEECCCCCCHHHHHHH
IARNTSASVNVIGLIGERGREVREFIEKDLGEEGLQRSVIVVATSDQPALLRIKGAMTAT
HHCCCCCCEEEEEEECCCCHHHHHHHHHHHCHHCCCCCEEEEEECCCCEEEEEECHHHHH
AIAEYFRDCGNDVMLMMDSVTRFATAKREVGLATGEPPATRGFPPSVFAMLPQLLERSGT
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
SDKGSVTGLYTVLVDGDDMDEPVSDTVRGVLDGHIVLSRKLAMQNHYPAIDILQSISRVM
CCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
VDITDTQHQKAAAKISSALAAYEEARDLIEIGAYKKGSNPKVDWAMELIDDLNEFLRQEI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TEKTTLDETINKLKKFLDD
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1828465; 9384377 [H]