Click here to switch to the map view.

The map label for this gene is fabD [H]

Identifier: 188585985

GI number: 188585985

Start: 1431132

End: 1432082

Strand: Direct

Name: fabD [H]

Synonym: Nther_1359

Alternate gene names: 188585985

Gene position: 1431132-1432082 (Clockwise)

Preceding gene: 188585984

Following gene: 188585986

Centisome position: 45.21

GC content: 37.75

Gene sequence:

>951_bases
ATGAAAAAACTAGGCTTTTTGTTTCCGGGCCAAGGTGCTCAATACGTAGGAATGGGAAAATTTCTATATGATAATTACCA
ACCAGCCCAAAAAATCTTCGAAACAGCAGGTGAAGTTCTGGGTTTTGATATAAAGGACAAGATTTTTAACGGAACAAAAG
AAGATTTACGTAAAACAGAATTAACACAACCAGCTATTTTGACAACTTCAGTCGCTTCTGCTACGGTATTACAGGAACAA
GGTTTGGCACCGCAAGGTGCTGCAGGGCTTAGTTTGGGAGAGTACAGTTCACTGGTGATAGCAGGATCCATCAAATTTGA
AGATGCTCTTGTTATTGTTCAAAGAAGAGGACAATATATGCAAGAAGCCGTCCCTGAAGGTAAAGGCAAAATGGTATCTG
TTTTAGGTTTAGAAGATAAACAGGTTGAAAAAGCTTGTGAAATGGTGAGAACAGAAACTGATAAATATGTGGTTCCTGCT
AATTATAACAGTCCTAAGCAGATTGTCATCTCCGGAGAGGCCGAGGGTGTTGAATTGGCCAAAGAGAAATGTCATGAACT
AGGTGCAAAAAGAACTAAAGAAGTTTCCGTAAGTGCGCCTTTTCATTGTGAATTACTTGAGCCAGCTGCAGCTAAACTAA
AGGTAGAACTGGATCAAATTGAAATTAAAGAACCAGAAATTGATGTAATATCAAATGTGACTGGAGAACCTTTTCAAACG
GCTCAAGAAGTCCGTGAAAATTTAATTAGACAGGTGAAATCCCCAGTGTTATTACATCAGTCGTTTACTAAAATGATTAA
CATGGGATATGATGGTTTTATCGATGTAGGTCCAGGTAACACTATGACGAAGCTTTTAAGTAAAGTTGACCGTAAGGTTT
ATCAGACTTCAGTTGATAAAGGAAATAATTTACAAGAATTGTTATCTAATAAGGAGGACCTGCTTAAATGA

Upstream 100 bases:

>100_bases
GAACAGAGTGCCAGGGAGATTATCGAAGAAGTTATGACTGAAGCTAAAAATTTAGTGGACAGTTTTGATTCAAAGAATTT
GGAAAGGTGAGGTGAAATGT

Downstream 100 bases:

>100_bases
GTAAAATTGCTGTTATTACTGGCGGTTCTAGGGGTATAGGTAGAAGTGTTACACTAAACTTAGCAAAAGCTGGGTATGAT
GTTTTAATTAATTATTCTTC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKKLGFLFPGQGAQYVGMGKFLYDNYQPAQKIFETAGEVLGFDIKDKIFNGTKEDLRKTELTQPAILTTSVASATVLQEQ
GLAPQGAAGLSLGEYSSLVIAGSIKFEDALVIVQRRGQYMQEAVPEGKGKMVSVLGLEDKQVEKACEMVRTETDKYVVPA
NYNSPKQIVISGEAEGVELAKEKCHELGAKRTKEVSVSAPFHCELLEPAAAKLKVELDQIEIKEPEIDVISNVTGEPFQT
AQEVRENLIRQVKSPVLLHQSFTKMINMGYDGFIDVGPGNTMTKLLSKVDRKVYQTSVDKGNNLQELLSNKEDLLK

Sequences:

>Translated_316_residues
MKKLGFLFPGQGAQYVGMGKFLYDNYQPAQKIFETAGEVLGFDIKDKIFNGTKEDLRKTELTQPAILTTSVASATVLQEQ
GLAPQGAAGLSLGEYSSLVIAGSIKFEDALVIVQRRGQYMQEAVPEGKGKMVSVLGLEDKQVEKACEMVRTETDKYVVPA
NYNSPKQIVISGEAEGVELAKEKCHELGAKRTKEVSVSAPFHCELLEPAAAKLKVELDQIEIKEPEIDVISNVTGEPFQT
AQEVRENLIRQVKSPVLLHQSFTKMINMGYDGFIDVGPGNTMTKLLSKVDRKVYQTSVDKGNNLQELLSNKEDLLK
>Mature_316_residues
MKKLGFLFPGQGAQYVGMGKFLYDNYQPAQKIFETAGEVLGFDIKDKIFNGTKEDLRKTELTQPAILTTSVASATVLQEQ
GLAPQGAAGLSLGEYSSLVIAGSIKFEDALVIVQRRGQYMQEAVPEGKGKMVSVLGLEDKQVEKACEMVRTETDKYVVPA
NYNSPKQIVISGEAEGVELAKEKCHELGAKRTKEVSVSAPFHCELLEPAAAKLKVELDQIEIKEPEIDVISNVTGEPFQT
AQEVRENLIRQVKSPVLLHQSFTKMINMGYDGFIDVGPGNTMTKLLSKVDRKVYQTSVDKGNNLQELLSNKEDLLK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=323, Percent_Identity=31.8885448916409, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=39.4495412844037, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1787334, Length=309, Percent_Identity=41.1003236245955, Blast_Score=221, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=32.9931972789116, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17550940, Length=322, Percent_Identity=26.3975155279503, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24665753, Length=310, Percent_Identity=33.2258064516129, Blast_Score=164, Evalue=7e-41,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34775; Mature: 34775

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLGFLFPGQGAQYVGMGKFLYDNYQPAQKIFETAGEVLGFDIKDKIFNGTKEDLRKTE
CCCCCCEECCCCCCEEECCHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHH
LTQPAILTTSVASATVLQEQGLAPQGAAGLSLGEYSSLVIAGSIKFEDALVIVQRRGQYM
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCHHH
QEAVPEGKGKMVSVLGLEDKQVEKACEMVRTETDKYVVPANYNSPKQIVISGEAEGVELA
HHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCCCHHHH
KEKCHELGAKRTKEVSVSAPFHCELLEPAAAKLKVELDQIEIKEPEIDVISNVTGEPFQT
HHHHHHHCCCCCCEEEECCCCEEEECCCCHHHEEEEEHHEEECCCCHHHHHCCCCCHHHH
AQEVRENLIRQVKSPVLLHQSFTKMINMGYDGFIDVGPGNTMTKLLSKVDRKVYQTSVDK
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCC
GNNLQELLSNKEDLLK
CCCHHHHHCCHHHHCC
>Mature Secondary Structure
MKKLGFLFPGQGAQYVGMGKFLYDNYQPAQKIFETAGEVLGFDIKDKIFNGTKEDLRKTE
CCCCCCEECCCCCCEEECCHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHH
LTQPAILTTSVASATVLQEQGLAPQGAAGLSLGEYSSLVIAGSIKFEDALVIVQRRGQYM
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCHHH
QEAVPEGKGKMVSVLGLEDKQVEKACEMVRTETDKYVVPANYNSPKQIVISGEAEGVELA
HHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCCCHHHH
KEKCHELGAKRTKEVSVSAPFHCELLEPAAAKLKVELDQIEIKEPEIDVISNVTGEPFQT
HHHHHHHCCCCCCEEEECCCCEEEECCCCHHHEEEEEHHEEECCCCHHHHHCCCCCHHHH
AQEVRENLIRQVKSPVLLHQSFTKMINMGYDGFIDVGPGNTMTKLLSKVDRKVYQTSVDK
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCC
GNNLQELLSNKEDLLK
CCCHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]