Click here to switch to the map view.

The map label for this gene is mraY [H]

Identifier: 188585927

GI number: 188585927

Start: 1373740

End: 1374696

Strand: Direct

Name: mraY [H]

Synonym: Nther_1301

Alternate gene names: 188585927

Gene position: 1373740-1374696 (Clockwise)

Preceding gene: 188585926

Following gene: 188585928

Centisome position: 43.4

GC content: 35.11

Gene sequence:

>957_bases
ATGGAAAAAATATACACATCAATATTAATAGCTTTTGTAATCAGTTTAGTATTATCACCCATTTTTATACCGTTATTGAG
GAAACTTAAGTTCGGACAGCAAATTAGAGATCAAGGACCAAAAAGCCATTATCAAAAATCAGGCACCCCAACTATGGGGG
GCGTGATTTTTCTCCTATCTGCTTTAATAAGTCTGCTTATTATCGCACCTTTGAACGGTGAAATCCTTATATTATTATTT
GTAACTTTGGCAACTGGTTTAATTGGATTTATGGATGATTTTCAAAAGGTTGTTAAAAAAAGAAGTCTTGGATTAAAGGG
CAGATATAAAATATTTGGCCAGTTACTTGTTGTAGCTGTGTTCTCTATTTATCTGAATTCTATTGATCACTCTACGGAAT
TATTAATCCCTTTCACAAATTTTGAAATAGATTTGGGATTTAGTTATTATCTGTTTCTTGCTTTGATGATTCTGGGTACC
TCTAATGCGGTTAATATTACAGATGGCTTAGATGGTTTAGCCACTGGAGTTGTAGTAATTTGCCTAACATCTTTTGTTAT
TTTGGCTCATATGCATAATCTAACTGGAACCGCTTTATTCGGAAGCGCTTTTATTGGAGCGTGTGCTGGGTTTCTAATAT
TTAACCTTCATCCTGCAAAAGTTTTTATGGGGGATGTAGGTAGTCTGGCTCTTGGAAGTGGATTGGCTTCCATGGCTGTT
TTAACCAAAGCCGAGTTAGCCCTGGTTATAATAGGTCTGACTTTGGTAATAGAAACTTTAAGTGTGATTGGGCAGGTAAT
ATTTTATCAAACTACAGGGAATCGTATTTTATTGATGAGCCCACTACATCATCACTTTGAATTAAAGGGATGGAGTGAAT
GGAAGGTTGTATTAGTTTTTTGGGTTTTTACTCTGATTACTGCCGCTATCGGGATTATTTCCGTGATTAATTTATAA

Upstream 100 bases:

>100_bases
AGATAGTTAAATCTGGAGATGGAATACTTGTTAAGGGTTCTAGAGGTATGGCTATGGAAAAGATAGTAAATTCGTTGTTA
AAAACTTAGGAGGATCGAAT

Downstream 100 bases:

>100_bases
ACAAAAGTTCAGATAGGAGAGAGACTATGTTTGATGATAAAGGCAAATATCTAATACTTGGATTAGGTAAAAGCGGCCAG
GGCGCTGTTATAGGTCTGAG

Product: Phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MEKIYTSILIAFVISLVLSPIFIPLLRKLKFGQQIRDQGPKSHYQKSGTPTMGGVIFLLSALISLLIIAPLNGEILILLF
VTLATGLIGFMDDFQKVVKKRSLGLKGRYKIFGQLLVVAVFSIYLNSIDHSTELLIPFTNFEIDLGFSYYLFLALMILGT
SNAVNITDGLDGLATGVVVICLTSFVILAHMHNLTGTALFGSAFIGACAGFLIFNLHPAKVFMGDVGSLALGSGLASMAV
LTKAELALVIIGLTLVIETLSVIGQVIFYQTTGNRILLMSPLHHHFELKGWSEWKVVLVFWVFTLITAAIGIISVINL

Sequences:

>Translated_318_residues
MEKIYTSILIAFVISLVLSPIFIPLLRKLKFGQQIRDQGPKSHYQKSGTPTMGGVIFLLSALISLLIIAPLNGEILILLF
VTLATGLIGFMDDFQKVVKKRSLGLKGRYKIFGQLLVVAVFSIYLNSIDHSTELLIPFTNFEIDLGFSYYLFLALMILGT
SNAVNITDGLDGLATGVVVICLTSFVILAHMHNLTGTALFGSAFIGACAGFLIFNLHPAKVFMGDVGSLALGSGLASMAV
LTKAELALVIIGLTLVIETLSVIGQVIFYQTTGNRILLMSPLHHHFELKGWSEWKVVLVFWVFTLITAAIGIISVINL
>Mature_318_residues
MEKIYTSILIAFVISLVLSPIFIPLLRKLKFGQQIRDQGPKSHYQKSGTPTMGGVIFLLSALISLLIIAPLNGEILILLF
VTLATGLIGFMDDFQKVVKKRSLGLKGRYKIFGQLLVVAVFSIYLNSIDHSTELLIPFTNFEIDLGFSYYLFLALMILGT
SNAVNITDGLDGLATGVVVICLTSFVILAHMHNLTGTALFGSAFIGACAGFLIFNLHPAKVFMGDVGSLALGSGLASMAV
LTKAELALVIIGLTLVIETLSVIGQVIFYQTTGNRILLMSPLHHHFELKGWSEWKVVLVFWVFTLITAAIGIISVINL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=331, Percent_Identity=43.8066465256798, Blast_Score=237, Evalue=9e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 34549; Mature: 34549

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIYTSILIAFVISLVLSPIFIPLLRKLKFGQQIRDQGPKSHYQKSGTPTMGGVIFLLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHH
ALISLLIIAPLNGEILILLFVTLATGLIGFMDDFQKVVKKRSLGLKGRYKIFGQLLVVAV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FSIYLNSIDHSTELLIPFTNFEIDLGFSYYLFLALMILGTSNAVNITDGLDGLATGVVVI
HHHHHHHCCCCCEEEEEEECEEEECCHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHH
CLTSFVILAHMHNLTGTALFGSAFIGACAGFLIFNLHPAKVFMGDVGSLALGSGLASMAV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHH
LTKAELALVIIGLTLVIETLSVIGQVIFYQTTGNRILLMSPLHHHFELKGWSEWKVVLVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEECCCCHHEECCCCCHHHHHHHH
WVFTLITAAIGIISVINL
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKIYTSILIAFVISLVLSPIFIPLLRKLKFGQQIRDQGPKSHYQKSGTPTMGGVIFLLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHH
ALISLLIIAPLNGEILILLFVTLATGLIGFMDDFQKVVKKRSLGLKGRYKIFGQLLVVAV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FSIYLNSIDHSTELLIPFTNFEIDLGFSYYLFLALMILGTSNAVNITDGLDGLATGVVVI
HHHHHHHCCCCCEEEEEEECEEEECCHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHH
CLTSFVILAHMHNLTGTALFGSAFIGACAGFLIFNLHPAKVFMGDVGSLALGSGLASMAV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHH
LTKAELALVIIGLTLVIETLSVIGQVIFYQTTGNRILLMSPLHHHFELKGWSEWKVVLVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEECCCCHHEECCCCCHHHHHHHH
WVFTLITAAIGIISVINL
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA