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The map label for this gene is argS [H]

Identifier: 188585877

GI number: 188585877

Start: 1323853

End: 1325553

Strand: Direct

Name: argS [H]

Synonym: Nther_1251

Alternate gene names: 188585877

Gene position: 1323853-1325553 (Clockwise)

Preceding gene: 188585875

Following gene: 188585878

Centisome position: 41.82

GC content: 36.8

Gene sequence:

>1701_bases
ATGGAAATTTTTCGCCAGAAAATAGCAGAGTTACTGCTGGAAGAAACCGGGCTTGATCTTGAGGACATTAAAGAAAACGT
TGAAGTTCCCCCGGACCGTAACCTGGGAGATTTTGCCTTTCCTTGTTTTAAACTGGCCAAGATAAAGAAAAAAAATCCAG
CTCAAATTGCATCGGAAATAGTTGAAAATATTGAAGCAGGAGAATACTTTTCAGCTATAGAAGCTACAGGTCCATATATT
AATTTCACCTGTAATCTTGAAAAATTAAACCAGGACACCTTAGAAAGGATTTATACCCAAGGCCGTGGATACGGAAAATC
TTCTGAAGGGGATGGGAAAACAGTAGTTATCGACTTTTCATCACCAAATATAGCCAAACCTTTTGGATTTGGTCACCTTC
GTTCTACTGTTATTGGCAATTCCCTGGCAAATGTTTATGAGACCTTAGGGTATAATGTGGAAAGAATTAATCATTTAGGA
GACTGGGGAACTCAGTTTGGCAATTTGATTGCCGCATATTTGAAATGGGGAAACGAACAAGAGTTAGAAAAAGACCCCAT
TGAATATTTATATGATTTGTATGTCAAGTTTCATGAAGAAATGGAAGAAGACCCGTCTTTGAAAGATGAAGGAAGGGAAT
GGTTTAGAAAGCTTGAGGAAGGCGATGAGACGGCGGAAAAGCTTTGGGAATGGTTTAGAGAAATGAGTTTAAAAGATTTT
GAACGTATTTACCGTAAACTTGGAGTTAAGTTTGATAGTAACAAAGGTGAAGCTTTTTACAATGATAAGTTGGAAGACAC
CATAGAAACCATCAAAGATTCTGGAATCGCTACTTATAGTCAAGGTGCATTAATTGTAGATTTAAACGAAGAAAATTTAC
CACCTTGTTTATTAAAGAAACAAGATGGTGCCACATTATACATTACTAGAGATTTAACTGCAGCCTTCTATCGATACGAA
AACTATCAATTTGATAAAGCTCTATATGTAGTGGGAGCTGATCAGGAACTGCATTTTAACCAAATGTTCAATGTTCTAAA
GAAAATGGGTTGTGATTGGGCTGAAAATATGGAGCATGTACCCTTTGGGTTAATTAGATTCCAAGATAGGAAAATGTCTA
CTCGCAAAGGAAATATGGTTTACTTAGAAGACGTTCTTGAAAAAGCAAAACAACTGGCCCTTGAAACTATTAGAGAAAAG
AACCCTGAATTAGATAATCAAGAAGATATTGCAGAAATGGTGGGAGTAGGAGCTGTAATTTTTGGTGACCTAAGCAATGA
CAGGGTTAAAGAAGTGAATTTTGATTGGGATAAAATTTTAGACTTCAATGGAGAAACAGCACCTTATTTACAATATACAC
ATGCGCGAATTTGTAGTGTATTGAAAAAAGCTGATATTACGCCAGAGTATGACAAAGACATAGTTAAGCACTTGCAGTCA
GACTATGAAAAGAATGTGATTCAGTTGTTGGCTGGATTCACAGATGCTTTAAAACGAACTAGGGATGCCAACAAACCTCA
TATACTAGCCAGGTATCTGCTGGATTTAGGTAGAGAATTCAACCGTTTTTATAACCATTGCCCTATCTTGAATGAAACCG
AAGAAGTAAAACAGGCTCGATTAATACTCATTGATGCTGTGAGACAGGTTTTAGCTAATGGCCTAGGTATTATGGGTATT
AAAGCTCCTGAAGCAATGTAA

Upstream 100 bases:

>100_bases
ATTTCTTGTTGGCACTGACAAATTGAGATATAATAAATCATGCATGCAATTAAAACATAAAATATTCATTTGAAATATTT
AAAGAAATGGGGGATAAGCT

Downstream 100 bases:

>100_bases
ATTAGTGATGGGAGGTGGAAACATTGATTACTTTTGAAAATTCCGGTCAGGATAATACAAATCGAGCTTTAGAGTTAGCT
GTAGAGCGTGGAAAAGAGCT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MEIFRQKIAELLLEETGLDLEDIKENVEVPPDRNLGDFAFPCFKLAKIKKKNPAQIASEIVENIEAGEYFSAIEATGPYI
NFTCNLEKLNQDTLERIYTQGRGYGKSSEGDGKTVVIDFSSPNIAKPFGFGHLRSTVIGNSLANVYETLGYNVERINHLG
DWGTQFGNLIAAYLKWGNEQELEKDPIEYLYDLYVKFHEEMEEDPSLKDEGREWFRKLEEGDETAEKLWEWFREMSLKDF
ERIYRKLGVKFDSNKGEAFYNDKLEDTIETIKDSGIATYSQGALIVDLNEENLPPCLLKKQDGATLYITRDLTAAFYRYE
NYQFDKALYVVGADQELHFNQMFNVLKKMGCDWAENMEHVPFGLIRFQDRKMSTRKGNMVYLEDVLEKAKQLALETIREK
NPELDNQEDIAEMVGVGAVIFGDLSNDRVKEVNFDWDKILDFNGETAPYLQYTHARICSVLKKADITPEYDKDIVKHLQS
DYEKNVIQLLAGFTDALKRTRDANKPHILARYLLDLGREFNRFYNHCPILNETEEVKQARLILIDAVRQVLANGLGIMGI
KAPEAM

Sequences:

>Translated_566_residues
MEIFRQKIAELLLEETGLDLEDIKENVEVPPDRNLGDFAFPCFKLAKIKKKNPAQIASEIVENIEAGEYFSAIEATGPYI
NFTCNLEKLNQDTLERIYTQGRGYGKSSEGDGKTVVIDFSSPNIAKPFGFGHLRSTVIGNSLANVYETLGYNVERINHLG
DWGTQFGNLIAAYLKWGNEQELEKDPIEYLYDLYVKFHEEMEEDPSLKDEGREWFRKLEEGDETAEKLWEWFREMSLKDF
ERIYRKLGVKFDSNKGEAFYNDKLEDTIETIKDSGIATYSQGALIVDLNEENLPPCLLKKQDGATLYITRDLTAAFYRYE
NYQFDKALYVVGADQELHFNQMFNVLKKMGCDWAENMEHVPFGLIRFQDRKMSTRKGNMVYLEDVLEKAKQLALETIREK
NPELDNQEDIAEMVGVGAVIFGDLSNDRVKEVNFDWDKILDFNGETAPYLQYTHARICSVLKKADITPEYDKDIVKHLQS
DYEKNVIQLLAGFTDALKRTRDANKPHILARYLLDLGREFNRFYNHCPILNETEEVKQARLILIDAVRQVLANGLGIMGI
KAPEAM
>Mature_566_residues
MEIFRQKIAELLLEETGLDLEDIKENVEVPPDRNLGDFAFPCFKLAKIKKKNPAQIASEIVENIEAGEYFSAIEATGPYI
NFTCNLEKLNQDTLERIYTQGRGYGKSSEGDGKTVVIDFSSPNIAKPFGFGHLRSTVIGNSLANVYETLGYNVERINHLG
DWGTQFGNLIAAYLKWGNEQELEKDPIEYLYDLYVKFHEEMEEDPSLKDEGREWFRKLEEGDETAEKLWEWFREMSLKDF
ERIYRKLGVKFDSNKGEAFYNDKLEDTIETIKDSGIATYSQGALIVDLNEENLPPCLLKKQDGATLYITRDLTAAFYRYE
NYQFDKALYVVGADQELHFNQMFNVLKKMGCDWAENMEHVPFGLIRFQDRKMSTRKGNMVYLEDVLEKAKQLALETIREK
NPELDNQEDIAEMVGVGAVIFGDLSNDRVKEVNFDWDKILDFNGETAPYLQYTHARICSVLKKADITPEYDKDIVKHLQS
DYEKNVIQLLAGFTDALKRTRDANKPHILARYLLDLGREFNRFYNHCPILNETEEVKQARLILIDAVRQVLANGLGIMGI
KAPEAM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI197100773, Length=514, Percent_Identity=36.9649805447471, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI15149476, Length=543, Percent_Identity=30.7550644567219, Blast_Score=230, Evalue=3e-60,
Organism=Escherichia coli, GI1788184, Length=562, Percent_Identity=34.1637010676157, Blast_Score=303, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI71985061, Length=585, Percent_Identity=30.5982905982906, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI71985068, Length=549, Percent_Identity=30.7832422586521, Blast_Score=206, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17532153, Length=492, Percent_Identity=29.0650406504065, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320548, Length=587, Percent_Identity=37.3083475298126, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6321883, Length=584, Percent_Identity=33.2191780821918, Blast_Score=376, Evalue=1e-105,
Organism=Drosophila melanogaster, GI28571570, Length=472, Percent_Identity=34.1101694915254, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI18859963, Length=536, Percent_Identity=30.9701492537313, Blast_Score=229, Evalue=3e-60,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 65162; Mature: 65162

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFRQKIAELLLEETGLDLEDIKENVEVPPDRNLGDFAFPCFKLAKIKKKNPAQIASEI
CHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
VENIEAGEYFSAIEATGPYINFTCNLEKLNQDTLERIYTQGRGYGKSSEGDGKTVVIDFS
HHHCCCCHHHHHHHCCCCEEEEEECHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECC
SPNIAKPFGFGHLRSTVIGNSLANVYETLGYNVERINHLGDWGTQFGNLIAAYLKWGNEQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ELEKDPIEYLYDLYVKFHEEMEEDPSLKDEGREWFRKLEEGDETAEKLWEWFREMSLKDF
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
ERIYRKLGVKFDSNKGEAFYNDKLEDTIETIKDSGIATYSQGALIVDLNEENLPPCLLKK
HHHHHHHCCEECCCCCCCEECCHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCEEEC
QDGATLYITRDLTAAFYRYENYQFDKALYVVGADQELHFNQMFNVLKKMGCDWAENMEHV
CCCCEEEEEHHHHHHHHHHCCCEECCEEEEEECCCCCCHHHHHHHHHHHCCCHHHCCCCC
PFGLIRFQDRKMSTRKGNMVYLEDVLEKAKQLALETIREKNPELDNQEDIAEMVGVGAVI
CCHHEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHE
FGDLSNDRVKEVNFDWDKILDFNGETAPYLQYTHARICSVLKKADITPEYDKDIVKHLQS
EECCCCCCCEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
DYEKNVIQLLAGFTDALKRTRDANKPHILARYLLDLGREFNRFYNHCPILNETEEVKQAR
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LILIDAVRQVLANGLGIMGIKAPEAM
HHHHHHHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure
MEIFRQKIAELLLEETGLDLEDIKENVEVPPDRNLGDFAFPCFKLAKIKKKNPAQIASEI
CHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
VENIEAGEYFSAIEATGPYINFTCNLEKLNQDTLERIYTQGRGYGKSSEGDGKTVVIDFS
HHHCCCCHHHHHHHCCCCEEEEEECHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECC
SPNIAKPFGFGHLRSTVIGNSLANVYETLGYNVERINHLGDWGTQFGNLIAAYLKWGNEQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ELEKDPIEYLYDLYVKFHEEMEEDPSLKDEGREWFRKLEEGDETAEKLWEWFREMSLKDF
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
ERIYRKLGVKFDSNKGEAFYNDKLEDTIETIKDSGIATYSQGALIVDLNEENLPPCLLKK
HHHHHHHCCEECCCCCCCEECCHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCEEEC
QDGATLYITRDLTAAFYRYENYQFDKALYVVGADQELHFNQMFNVLKKMGCDWAENMEHV
CCCCEEEEEHHHHHHHHHHCCCEECCEEEEEECCCCCCHHHHHHHHHHHCCCHHHCCCCC
PFGLIRFQDRKMSTRKGNMVYLEDVLEKAKQLALETIREKNPELDNQEDIAEMVGVGAVI
CCHHEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHE
FGDLSNDRVKEVNFDWDKILDFNGETAPYLQYTHARICSVLKKADITPEYDKDIVKHLQS
EECCCCCCCEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
DYEKNVIQLLAGFTDALKRTRDANKPHILARYLLDLGREFNRFYNHCPILNETEEVKQAR
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LILIDAVRQVLANGLGIMGIKAPEAM
HHHHHHHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA