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The map label for this gene is 188585850

Identifier: 188585850

GI number: 188585850

Start: 1298599

End: 1299402

Strand: Direct

Name: 188585850

Synonym: Nther_1224

Alternate gene names: NA

Gene position: 1298599-1299402 (Clockwise)

Preceding gene: 188585847

Following gene: 188585851

Centisome position: 41.02

GC content: 33.71

Gene sequence:

>804_bases
ATGTCCACAGGATTAGACAGTAAAAGAATGATAACAGATGGAAACAAATTCAAAAAGGTAGTTGATCTGAAAGCTGATAG
TGTCCAATTACCAACGGGGATTCTAACAGGTGAAAAGTTGCGACAGTTATCTCCAGGTTCGGAATTTTATTTAAACGAAA
AAAAATACTTTATATTTGAATGTACATTAGCTGATTTTCTTGAAAAAAAATTAGAGAGAAAGACTCAAATTATGTATCCT
AAAGAAATCAGTTTTATGATTTATAAACTTGATATTTCACCAGGTGATAGTGTAGGCGAAGCGGGTACTGGTTCTGGTGC
CATGACACTGTCCTTGTCTCGTACAGTAGGTCCCCAAGGGAGTGTATACACTTATGAAAGGAGATCAGACTTCAGTAAAT
TAGTAAATAAAAACTATTCTAGGGGAAGAAAATTTGATAATGTAACCTTTTACAATCAATCAATAGAAGAAGGAATTTTT
GAAACCGACTTAGATGCGTTTGTACTAGATGTGAGAGAGCCCTGGGAAGTACTAGACAAAATAAGTCATTCTTTAAAACC
TTCGGGAAATTTAGGTGTATTAGTACCCACATATAATCAGATTAGTGCTACGCTTCCAGAATTAAAAGATAATAGTTTCT
TTGTAACAGACATTGTTGAATTGTTATTGAGAAGATATAAACATAACCCAGAACGTATGCGACCTGAAGATACAATGATA
GGGCATACAGGTTATTTGATAATTGCCAAAAAATTAACAGGTGAAACTAAAAGTTTAGAAGAAATTTCTGAATGTGAGGA
ATGA

Upstream 100 bases:

>100_bases
AAACAAAACTCATGTATTATTTCACCTCCTGGAATTATTATAATAAATTTTGATTGAAGTTAAAATATAAATCAAAGTTT
TTATGTAAGGAGTGATAGAA

Downstream 100 bases:

>100_bases
TTCTCTCTTTTATTGTGTTTTGGCTTGTAATGTAATATAATAACATAAAAGACATAATAAGAATTGTATCAGGGATTGTT
AATCTAATAACAAAAGTGTG

Product: tRNA methyltransferase complex GCD14 subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSTGLDSKRMITDGNKFKKVVDLKADSVQLPTGILTGEKLRQLSPGSEFYLNEKKYFIFECTLADFLEKKLERKTQIMYP
KEISFMIYKLDISPGDSVGEAGTGSGAMTLSLSRTVGPQGSVYTYERRSDFSKLVNKNYSRGRKFDNVTFYNQSIEEGIF
ETDLDAFVLDVREPWEVLDKISHSLKPSGNLGVLVPTYNQISATLPELKDNSFFVTDIVELLLRRYKHNPERMRPEDTMI
GHTGYLIIAKKLTGETKSLEEISECEE

Sequences:

>Translated_267_residues
MSTGLDSKRMITDGNKFKKVVDLKADSVQLPTGILTGEKLRQLSPGSEFYLNEKKYFIFECTLADFLEKKLERKTQIMYP
KEISFMIYKLDISPGDSVGEAGTGSGAMTLSLSRTVGPQGSVYTYERRSDFSKLVNKNYSRGRKFDNVTFYNQSIEEGIF
ETDLDAFVLDVREPWEVLDKISHSLKPSGNLGVLVPTYNQISATLPELKDNSFFVTDIVELLLRRYKHNPERMRPEDTMI
GHTGYLIIAKKLTGETKSLEEISECEE
>Mature_266_residues
STGLDSKRMITDGNKFKKVVDLKADSVQLPTGILTGEKLRQLSPGSEFYLNEKKYFIFECTLADFLEKKLERKTQIMYPK
EISFMIYKLDISPGDSVGEAGTGSGAMTLSLSRTVGPQGSVYTYERRSDFSKLVNKNYSRGRKFDNVTFYNQSIEEGIFE
TDLDAFVLDVREPWEVLDKISHSLKPSGNLGVLVPTYNQISATLPELKDNSFFVTDIVELLLRRYKHNPERMRPEDTMIG
HTGYLIIAKKLTGETKSLEEISECEE

Specific function: Unknown

COG id: COG2519

COG function: function code J; tRNA(1-methyladenosine) methyltransferase and related methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TRM61 family [H]

Homologues:

Organism=Homo sapiens, GI222831587, Length=188, Percent_Identity=32.9787234042553, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI123173772, Length=210, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014816 [H]

Pfam domain/function: PF08704 GCD14 [H]

EC number: =2.1.1.36 [H]

Molecular weight: Translated: 30317; Mature: 30186

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGLDSKRMITDGNKFKKVVDLKADSVQLPTGILTGEKLRQLSPGSEFYLNEKKYFIFE
CCCCCCCCCEECCCHHHHHHHCCCCCCEECCCCCCCHHHHHHCCCCCCEEECCCEEEEEE
CTLADFLEKKLERKTQIMYPKEISFMIYKLDISPGDSVGEAGTGSGAMTLSLSRTVGPQG
EHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCC
SVYTYERRSDFSKLVNKNYSRGRKFDNVTFYNQSIEEGIFETDLDAFVLDVREPWEVLDK
CEEEEHHHHHHHHHHHCCHHCCCCCCCEEEECCHHHHCHHHCCCHHEEEECCCHHHHHHH
ISHSLKPSGNLGVLVPTYNQISATLPELKDNSFFVTDIVELLLRRYKHNPERMRPEDTMI
HHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCEE
GHTGYLIIAKKLTGETKSLEEISECEE
CCCCEEEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
STGLDSKRMITDGNKFKKVVDLKADSVQLPTGILTGEKLRQLSPGSEFYLNEKKYFIFE
CCCCCCCCEECCCHHHHHHHCCCCCCEECCCCCCCHHHHHHCCCCCCEEECCCEEEEEE
CTLADFLEKKLERKTQIMYPKEISFMIYKLDISPGDSVGEAGTGSGAMTLSLSRTVGPQG
EHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCC
SVYTYERRSDFSKLVNKNYSRGRKFDNVTFYNQSIEEGIFETDLDAFVLDVREPWEVLDK
CEEEEHHHHHHHHHHHCCHHCCCCCCCEEEECCHHHHCHHHCCCHHEEEECCCHHHHHHH
ISHSLKPSGNLGVLVPTYNQISATLPELKDNSFFVTDIVELLLRRYKHNPERMRPEDTMI
HHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCEE
GHTGYLIIAKKLTGETKSLEEISECEE
CCCCEEEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]