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The map label for this gene is codB [H]

Identifier: 188585490

GI number: 188585490

Start: 908405

End: 909772

Strand: Direct

Name: codB [H]

Synonym: Nther_0862

Alternate gene names: 188585490

Gene position: 908405-909772 (Clockwise)

Preceding gene: 188585487

Following gene: 188585491

Centisome position: 28.7

GC content: 40.06

Gene sequence:

>1368_bases
ATGAGTGATAAGACAAATCAAGCTGATGTCTTTGAGGATCATGCAGTTTCGGCAGTTCCAAAAGAACAACAGCGCAGTTT
CACAGGAATGTTTATGGTTTATACTGGTGTGTTAGTTTGTATGGCCGTCATTTGGACAGGTGGTGAATTAGGTCGAGGAT
TAGCACTTAATAATATGATTCTTGCAATCTTAGGTGGTTCTGTAATAACAGCCATAATTGGACTATTAACTGGTATTATT
GGTGGCTATACTAGAACGTCTACATATGTTATTCTCAGACATTCTTTTGGACGTTATGGTTCCATGGTAGCCGGTGCTGC
TGTTTCGGGAATATCTTGCGGAATCGGCTGGTTTTTTATACAAGCATGGTTGTTTTCAGAAGTTATGGAAACGATTTCAC
TTGAGCTGTGGGGCTCTGTTCCTTATCTATTTCAGGGTCATATTTCTGCTTTTTGGGGAGCTATATTAATGACTTTAACT
GCTATTTTTGGGTTTAAAGGTCTAGCTTTATTAAGTTATGTCACAGTTCCTCTCTTTATTGTGATTTTAGGAGGCGGTTC
CGTTGCTGCAATCACTGAAGCTGGTGGATTTAGCCAAATAGCTCAGGCAACACCAGCTGAACCAATGACTATAGGTGCAG
CTATTACTGCCATTGTAGGAAGCTATATAGCAGGAGCAACCATTTCACCTGATATTGCTAGATATGCAGCAAAACCAACT
CACGGTGGTTGGGCTTGGTTTTGGCAAGTTTTATTTATGCAGCCTCTGCTGTTTTTAGCTGCTGGTCTATTGACATTGCT
CACTCCTCAAGCCGATGTAGCCGAGGCTATGGCTCATCTAGGAATTGGAGTAGGGGCTTTACTGATAGTTATTCTTGGAC
AGTGGACCACAAATGACAACAATTTGTACAATGGTGCTTTGGCTTTTGCTAACACCATAAAAGTTAAAAAAGCTGTCATT
ACAGGTATTCTTGGTTTTGTGGGAGCAATCCTAGCTTCATTAACAGCTCTAGGTGTTTTTGGTGCCGATCCATTTATGAC
TTTTTTAAATCAACTAGGTCGTTTTTTACCACCAATTGCAGGTATTCTAATAGCCGATTTTTATATTCTCAAGCCTTATT
TACAGGGTAAAAAGGACCCCGAGAATAGATACCAGTTCGGTCCTGGTACTGAATACGCTTGCATAAACTGGGTGGGGATT
CTCAGTTGGATTGGAGCTGGATATTTCAGTGTTTATCTCCCCGGAATTGTAGCATTGAATTCAATTTTGCTTAGCTTTAT
AGCCTTCATTATATTAACTTATACTTGTGAAATGTTCAATATCCAGTATACAAGTGGCAGCTACGTGGAAGAAAGCACAG
GATTTTAA

Upstream 100 bases:

>100_bases
CTATAAGTGTTTAAACTTAATTGGAGGTGATGTTAAAAGTTGTGAATTTAAATAAATTTCAAAAATAGCAAAAATTCAAA
AAACAGGGAGGGAGTTTTAA

Downstream 100 bases:

>100_bases
AAAATCGATAAGAAAGAAAAATTGGAGGTGTCAATAATGTTGAAAGATGTTTCATGGTATAGAAAAAATGTTAGCTCCTT
GATGCTTTCTCTAGGGATAG

Product: permease for cytosine/purines uracil thiamine allantoin

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSDKTNQADVFEDHAVSAVPKEQQRSFTGMFMVYTGVLVCMAVIWTGGELGRGLALNNMILAILGGSVITAIIGLLTGII
GGYTRTSTYVILRHSFGRYGSMVAGAAVSGISCGIGWFFIQAWLFSEVMETISLELWGSVPYLFQGHISAFWGAILMTLT
AIFGFKGLALLSYVTVPLFIVILGGGSVAAITEAGGFSQIAQATPAEPMTIGAAITAIVGSYIAGATISPDIARYAAKPT
HGGWAWFWQVLFMQPLLFLAAGLLTLLTPQADVAEAMAHLGIGVGALLIVILGQWTTNDNNLYNGALAFANTIKVKKAVI
TGILGFVGAILASLTALGVFGADPFMTFLNQLGRFLPPIAGILIADFYILKPYLQGKKDPENRYQFGPGTEYACINWVGI
LSWIGAGYFSVYLPGIVALNSILLSFIAFIILTYTCEMFNIQYTSGSYVEESTGF

Sequences:

>Translated_455_residues
MSDKTNQADVFEDHAVSAVPKEQQRSFTGMFMVYTGVLVCMAVIWTGGELGRGLALNNMILAILGGSVITAIIGLLTGII
GGYTRTSTYVILRHSFGRYGSMVAGAAVSGISCGIGWFFIQAWLFSEVMETISLELWGSVPYLFQGHISAFWGAILMTLT
AIFGFKGLALLSYVTVPLFIVILGGGSVAAITEAGGFSQIAQATPAEPMTIGAAITAIVGSYIAGATISPDIARYAAKPT
HGGWAWFWQVLFMQPLLFLAAGLLTLLTPQADVAEAMAHLGIGVGALLIVILGQWTTNDNNLYNGALAFANTIKVKKAVI
TGILGFVGAILASLTALGVFGADPFMTFLNQLGRFLPPIAGILIADFYILKPYLQGKKDPENRYQFGPGTEYACINWVGI
LSWIGAGYFSVYLPGIVALNSILLSFIAFIILTYTCEMFNIQYTSGSYVEESTGF
>Mature_454_residues
SDKTNQADVFEDHAVSAVPKEQQRSFTGMFMVYTGVLVCMAVIWTGGELGRGLALNNMILAILGGSVITAIIGLLTGIIG
GYTRTSTYVILRHSFGRYGSMVAGAAVSGISCGIGWFFIQAWLFSEVMETISLELWGSVPYLFQGHISAFWGAILMTLTA
IFGFKGLALLSYVTVPLFIVILGGGSVAAITEAGGFSQIAQATPAEPMTIGAAITAIVGSYIAGATISPDIARYAAKPTH
GGWAWFWQVLFMQPLLFLAAGLLTLLTPQADVAEAMAHLGIGVGALLIVILGQWTTNDNNLYNGALAFANTIKVKKAVIT
GILGFVGAILASLTALGVFGADPFMTFLNQLGRFLPPIAGILIADFYILKPYLQGKKDPENRYQFGPGTEYACINWVGIL
SWIGAGYFSVYLPGIVALNSILLSFIAFIILTYTCEMFNIQYTSGSYVEESTGF

Specific function: Required for cytosine transport into the cell [H]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI1786530, Length=450, Percent_Identity=28.4444444444444, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 48509; Mature: 48378

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKTNQADVFEDHAVSAVPKEQQRSFTGMFMVYTGVLVCMAVIWTGGELGRGLALNNMI
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHH
LAILGGSVITAIIGLLTGIIGGYTRTSTYVILRHSFGRYGSMVAGAAVSGISCGIGWFFI
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
QAWLFSEVMETISLELWGSVPYLFQGHISAFWGAILMTLTAIFGFKGLALLSYVTVPLFI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILGGGSVAAITEAGGFSQIAQATPAEPMTIGAAITAIVGSYIAGATISPDIARYAAKPT
HHCCCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
HGGWAWFWQVLFMQPLLFLAAGLLTLLTPQADVAEAMAHLGIGVGALLIVILGQWTTNDN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
NLYNGALAFANTIKVKKAVITGILGFVGAILASLTALGVFGADPFMTFLNQLGRFLPPIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GILIADFYILKPYLQGKKDPENRYQFGPGTEYACINWVGILSWIGAGYFSVYLPGIVALN
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILLSFIAFIILTYTCEMFNIQYTSGSYVEESTGF
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SDKTNQADVFEDHAVSAVPKEQQRSFTGMFMVYTGVLVCMAVIWTGGELGRGLALNNMI
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHH
LAILGGSVITAIIGLLTGIIGGYTRTSTYVILRHSFGRYGSMVAGAAVSGISCGIGWFFI
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
QAWLFSEVMETISLELWGSVPYLFQGHISAFWGAILMTLTAIFGFKGLALLSYVTVPLFI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILGGGSVAAITEAGGFSQIAQATPAEPMTIGAAITAIVGSYIAGATISPDIARYAAKPT
HHCCCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
HGGWAWFWQVLFMQPLLFLAAGLLTLLTPQADVAEAMAHLGIGVGALLIVILGQWTTNDN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
NLYNGALAFANTIKVKKAVITGILGFVGAILASLTALGVFGADPFMTFLNQLGRFLPPIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GILIADFYILKPYLQGKKDPENRYQFGPGTEYACINWVGILSWIGAGYFSVYLPGIVALN
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILLSFIAFIILTYTCEMFNIQYTSGSYVEESTGF
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]