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The map label for this gene is ycbL [C]

Identifier: 188585460

GI number: 188585460

Start: 868757

End: 869731

Strand: Direct

Name: ycbL [C]

Synonym: Nther_0832

Alternate gene names: 188585460

Gene position: 868757-869731 (Clockwise)

Preceding gene: 188585449

Following gene: 188585462

Centisome position: 27.44

GC content: 36.0

Gene sequence:

>975_bases
ATGCCAGAAGAAATTTTGAAAGATATTTATAGAATTGAAGTACCATTGCCACGTAACCCATTAAAAGCAATCAATTCTTA
CTTAATCAAAGGTCAAGAGAGGAACCTACTCATCGATACAGGAATGAATAGACAGGAGTGTAGCAAAGCACTTACCACAG
CTCTTGATACTTTAAAGGTGGATATGACAAAAACCGACCTTTTAATAACACATTTGCATGCCGATCACATAGGGCTTGCT
TTTAATCTTGCATTCGAGGATTCAAACATCTATTTCAACCCTTTGGATGCCAAGATACTTGGTGATAATAACTTCTGGAA
CAAAAATCAGCAACTAGCTTCTAAGAACGGCTTTCCAAAAGATCTACTTGAAGAAGCCGTAAAAAAACACCCGGGTTACA
AATATACCCCTGAGATATCAAAAGAATTTACTTTTATACAAGAAGATGAAGTGATAGAAGTCGGTGACTACCAACTAAAG
TGTATTGAAACACCAGGTCATACTCCTGGAAATATTTGTCTCTACGATGATGATAAAAAGATCCTTTTTTCGGGTGATCA
CGTCTTGTGGAATATCACCCCAAATATATCAGCCTCTATAGATCCCAATGGTAACCCTTTAAAGGATTACATTAATAGTC
TAGATAAAGTCCGGGATTTAGAAGTAGAGTTAGTCTTACCAGCTCATCGAAGCCTATTTTATGATTTGAGTAAAAGAGTA
GATCAACTTAAACTTCATCATCAGATGAGGGAAAAGGAGATTGAAGAAATACTACATGATAATAAAAAGCTAACTGCATA
TCAATTGGCTTCACTTATGAGTTGGGAGATAAAATGTAATTCATGGGAAGATTTTCCCCTTGTACAGAAATGGTTTGCAA
CAGAAGAGGCCCTTGCTCACTTAAAGTATATGGAAGATAAGGGCACTATAGGGAAAAAAGTGACTGAAAGTATTATCCAT
TACCACCTTAATTAA

Upstream 100 bases:

>100_bases
GAATATTTTTGGTTTAGTAATGCGAAATTCGTAGGATTTTTGGACGAATTGTAGAAGTGATATTAAGACATATCAGACTA
TTGAAATAGGAGGGTAATTG

Downstream 100 bases:

>100_bases
TGATAATGAATTTAGGTAGCTAATCATTTGAGGAGTTAACAGCTATGGAAATAAAAATGAGACTATAGCCACAACCAGTT
TTTGGTTATGGCTATTATTT

Product: beta-lactamase domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MPEEILKDIYRIEVPLPRNPLKAINSYLIKGQERNLLIDTGMNRQECSKALTTALDTLKVDMTKTDLLITHLHADHIGLA
FNLAFEDSNIYFNPLDAKILGDNNFWNKNQQLASKNGFPKDLLEEAVKKHPGYKYTPEISKEFTFIQEDEVIEVGDYQLK
CIETPGHTPGNICLYDDDKKILFSGDHVLWNITPNISASIDPNGNPLKDYINSLDKVRDLEVELVLPAHRSLFYDLSKRV
DQLKLHHQMREKEIEEILHDNKKLTAYQLASLMSWEIKCNSWEDFPLVQKWFATEEALAHLKYMEDKGTIGKKVTESIIH
YHLN

Sequences:

>Translated_324_residues
MPEEILKDIYRIEVPLPRNPLKAINSYLIKGQERNLLIDTGMNRQECSKALTTALDTLKVDMTKTDLLITHLHADHIGLA
FNLAFEDSNIYFNPLDAKILGDNNFWNKNQQLASKNGFPKDLLEEAVKKHPGYKYTPEISKEFTFIQEDEVIEVGDYQLK
CIETPGHTPGNICLYDDDKKILFSGDHVLWNITPNISASIDPNGNPLKDYINSLDKVRDLEVELVLPAHRSLFYDLSKRV
DQLKLHHQMREKEIEEILHDNKKLTAYQLASLMSWEIKCNSWEDFPLVQKWFATEEALAHLKYMEDKGTIGKKVTESIIH
YHLN
>Mature_323_residues
PEEILKDIYRIEVPLPRNPLKAINSYLIKGQERNLLIDTGMNRQECSKALTTALDTLKVDMTKTDLLITHLHADHIGLAF
NLAFEDSNIYFNPLDAKILGDNNFWNKNQQLASKNGFPKDLLEEAVKKHPGYKYTPEISKEFTFIQEDEVIEVGDYQLKC
IETPGHTPGNICLYDDDKKILFSGDHVLWNITPNISASIDPNGNPLKDYINSLDKVRDLEVELVLPAHRSLFYDLSKRVD
QLKLHHQMREKEIEEILHDNKKLTAYQLASLMSWEIKCNSWEDFPLVQKWFATEEALAHLKYMEDKGTIGKKVTESIIHY
HLN

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI42822880, Length=231, Percent_Identity=27.7056277056277, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI7705793, Length=274, Percent_Identity=22.2627737226277, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193205216, Length=302, Percent_Identity=26.4900662251656, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17537503, Length=302, Percent_Identity=26.4900662251656, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 37433; Mature: 37302

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEEILKDIYRIEVPLPRNPLKAINSYLIKGQERNLLIDTGMNRQECSKALTTALDTLKV
CCHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHEE
DMTKTDLLITHLHADHIGLAFNLAFEDSNIYFNPLDAKILGDNNFWNKNQQLASKNGFPK
ECCHHEEEEEEECCCCCEEEEEEEEECCCEEECCCCCEEECCCCCCCCCHHHHHCCCCCH
DLLEEAVKKHPGYKYTPEISKEFTFIQEDEVIEVGDYQLKCIETPGHTPGNICLYDDDKK
HHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEECCEEEEEECCCCCCCCCEEEEECCCE
ILFSGDHVLWNITPNISASIDPNGNPLKDYINSLDKVRDLEVELVLPAHRSLFYDLSKRV
EEEECCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHH
DQLKLHHQMREKEIEEILHDNKKLTAYQLASLMSWEIKCNSWEDFPLVQKWFATEEALAH
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHH
LKYMEDKGTIGKKVTESIIHYHLN
HHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PEEILKDIYRIEVPLPRNPLKAINSYLIKGQERNLLIDTGMNRQECSKALTTALDTLKV
CHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHEE
DMTKTDLLITHLHADHIGLAFNLAFEDSNIYFNPLDAKILGDNNFWNKNQQLASKNGFPK
ECCHHEEEEEEECCCCCEEEEEEEEECCCEEECCCCCEEECCCCCCCCCHHHHHCCCCCH
DLLEEAVKKHPGYKYTPEISKEFTFIQEDEVIEVGDYQLKCIETPGHTPGNICLYDDDKK
HHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEECCEEEEEECCCCCCCCCEEEEECCCE
ILFSGDHVLWNITPNISASIDPNGNPLKDYINSLDKVRDLEVELVLPAHRSLFYDLSKRV
EEEECCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHH
DQLKLHHQMREKEIEEILHDNKKLTAYQLASLMSWEIKCNSWEDFPLVQKWFATEEALAH
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHH
LKYMEDKGTIGKKVTESIIHYHLN
HHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]