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The map label for this gene is hsdM [C]

Identifier: 188585422

GI number: 188585422

Start: 825745

End: 827610

Strand: Direct

Name: hsdM [C]

Synonym: Nther_0792

Alternate gene names: 188585422

Gene position: 825745-827610 (Clockwise)

Preceding gene: 188585421

Following gene: 188585423

Centisome position: 26.09

GC content: 32.32

Gene sequence:

>1866_bases
ATGGAACATAAACATATTTTTCAGTTGTGTGAACATTTGCGAGGAGAGCTCCAACCTGAAGAATACTTAGATGTTATATT
CCCAGTTTTAACTATAAAACACATCTCTGAGACTAAATCCCCTTACTATATTCCAGAAGACGCTACTTGGAATTGTTTGA
TAGCGAGTGGACTTAACTTGGTTAAAAGAGTTGAAAAAGCAATTGAATTGATAGAGGGAAATAATTATAGATTAAATAAT
GTCCTTAACATTTTTCCAGGTAAGTCGTTATCTGATGTTAATTTATATAATTTTATGCTAGGTATAGATGAGATTCAAGA
TCACAAACAGTTTTTAAAAACTGTAATTGACCACTTTTCTAAAAGGATAGGCAAAGCCTCCGGGGTATGGCACACTTCAA
ACACATTAAATGAACTAATAGTAAGGTTGATTGCCCCTATGGATGGTAGTTTTTATGACGGAACAGCAGGGTTGTGTAAT
ACTCTCATTGAAGCTTCTGAATTTGCAGAACAAGAGGGAGGTGCATTACAGTTATATGGGCAAGAAATAGATCCTAAAAT
CTGGGCACTTGGTAAAATAAACCTAATATTTAATGAATGTCATGATGTAGTATTAGAAAGAGAAGACTCATTAAGAAATC
CTATGACTACAGAAGATAATAATTTAAAAACTTTTGATTATATTGGGATGAATATTCCTTTTGGATTACGTGACTGGGGC
GTTGAGGAAGCTAGAAGAGATCTTTTTGGTAGATTCCGATATGGTATTCCTAGTAAGCAGCATGGAGATATGGCTTTTAT
ATTACATGCATTAACATCGTTAAACCGATCTGGTAAAGCTGCAATAGTTGTACCGCACGGAGTATTATTTAGGGGAGGTA
GAGAAGCTAAAATTAGAGAAAAATTAATCAATAATGACGTTATTGAAGGAGTCGTAGATTTACCGTCTGGATTATTAGCA
GGAACTAATATTCCAGTTTCTATAATAATTTTAAATAAACTTAAACCTGAAGAATCAACTGAGAAAATTTTTATGGTTAA
TGCCAAAGATATTGAACATAAGGGATTTGAATTACCTAGAGAAGATTTAGATATGATCATTGAAGCATACATTAGAAAGG
ATACTATTGATGGTTTTAGTATGTGGATCAATAGAGAAGATATAATAGATCACAGCTTATTAGTTAAAAATTACTTTGAA
GATTGTGAAGTGACAACTCCTATTGGTAAGTTTGAGATTGATCGAAAGGATTATGAAAATAATACTGAAACTGTTTCTTT
AAAAAGCTTAGGTACTTTCTATAGAGGATTAAATACTCATGCATACAAAACCCAGAAGTCTGAATCCCCAACCCATAAAA
TACTTCAATTATCCAATGTAGAGAATGGTGAGATTTTTCTTGAAAATGCCGATTCTTATAATGCTAAAGAACTAAAAAAT
CCAAGTTCGTATGAAGTTCAGCCAGGTGATGTAATTATTTCAAGTCGAGGTAATTCTATTAAAATTGCTGTTATTCCAGA
AGAAATTGAAAACACACTATTATCTCATAATTTTATCGGTTTTAGGCCTAATGACAATGTCGACCCCTATTTTATTAAGT
ATTTCATGGAAAGTCCTATAGGTATTAAATACCTTTCCTTATATCAGAAGGGATCCGCTGTCTCTGTGTTGAAAGTTAAA
GATATTGAGAAAATCTATATACCTAAGGTTTCATTAGAGGAACAAAAAGCAATCTCTAATAAGTTAAGAAATGCTGATTT
GACGTTACAAAGGAAAATACAAAAAGCTAAAGAGGAACATAAACAACTGTACCTTTATGCTTATAGAAGTTTAGGTATTC
ATGAAAGTATCACAGAGAAGAAGTGA

Upstream 100 bases:

>100_bases
GATCTCATGGACTTTGGGTATATGGAACTAATAGAAGTCTCGATTATGCTTTAAAAGTTTCTAGAGACGTAATAAAAAAC
TTATAAAGGGAGGATGTAAA

Downstream 100 bases:

>100_bases
CCCATTTATCTCTGTGATCAATGAAGACAAAGGTATCTCTGTTAGATTCAATTACTGTAAAAATATGCTATAATTTTAGT
TATGATGGGGTTATAGAACT

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MEHKHIFQLCEHLRGELQPEEYLDVIFPVLTIKHISETKSPYYIPEDATWNCLIASGLNLVKRVEKAIELIEGNNYRLNN
VLNIFPGKSLSDVNLYNFMLGIDEIQDHKQFLKTVIDHFSKRIGKASGVWHTSNTLNELIVRLIAPMDGSFYDGTAGLCN
TLIEASEFAEQEGGALQLYGQEIDPKIWALGKINLIFNECHDVVLEREDSLRNPMTTEDNNLKTFDYIGMNIPFGLRDWG
VEEARRDLFGRFRYGIPSKQHGDMAFILHALTSLNRSGKAAIVVPHGVLFRGGREAKIREKLINNDVIEGVVDLPSGLLA
GTNIPVSIIILNKLKPEESTEKIFMVNAKDIEHKGFELPREDLDMIIEAYIRKDTIDGFSMWINREDIIDHSLLVKNYFE
DCEVTTPIGKFEIDRKDYENNTETVSLKSLGTFYRGLNTHAYKTQKSESPTHKILQLSNVENGEIFLENADSYNAKELKN
PSSYEVQPGDVIISSRGNSIKIAVIPEEIENTLLSHNFIGFRPNDNVDPYFIKYFMESPIGIKYLSLYQKGSAVSVLKVK
DIEKIYIPKVSLEEQKAISNKLRNADLTLQRKIQKAKEEHKQLYLYAYRSLGIHESITEKK

Sequences:

>Translated_621_residues
MEHKHIFQLCEHLRGELQPEEYLDVIFPVLTIKHISETKSPYYIPEDATWNCLIASGLNLVKRVEKAIELIEGNNYRLNN
VLNIFPGKSLSDVNLYNFMLGIDEIQDHKQFLKTVIDHFSKRIGKASGVWHTSNTLNELIVRLIAPMDGSFYDGTAGLCN
TLIEASEFAEQEGGALQLYGQEIDPKIWALGKINLIFNECHDVVLEREDSLRNPMTTEDNNLKTFDYIGMNIPFGLRDWG
VEEARRDLFGRFRYGIPSKQHGDMAFILHALTSLNRSGKAAIVVPHGVLFRGGREAKIREKLINNDVIEGVVDLPSGLLA
GTNIPVSIIILNKLKPEESTEKIFMVNAKDIEHKGFELPREDLDMIIEAYIRKDTIDGFSMWINREDIIDHSLLVKNYFE
DCEVTTPIGKFEIDRKDYENNTETVSLKSLGTFYRGLNTHAYKTQKSESPTHKILQLSNVENGEIFLENADSYNAKELKN
PSSYEVQPGDVIISSRGNSIKIAVIPEEIENTLLSHNFIGFRPNDNVDPYFIKYFMESPIGIKYLSLYQKGSAVSVLKVK
DIEKIYIPKVSLEEQKAISNKLRNADLTLQRKIQKAKEEHKQLYLYAYRSLGIHESITEKK
>Mature_621_residues
MEHKHIFQLCEHLRGELQPEEYLDVIFPVLTIKHISETKSPYYIPEDATWNCLIASGLNLVKRVEKAIELIEGNNYRLNN
VLNIFPGKSLSDVNLYNFMLGIDEIQDHKQFLKTVIDHFSKRIGKASGVWHTSNTLNELIVRLIAPMDGSFYDGTAGLCN
TLIEASEFAEQEGGALQLYGQEIDPKIWALGKINLIFNECHDVVLEREDSLRNPMTTEDNNLKTFDYIGMNIPFGLRDWG
VEEARRDLFGRFRYGIPSKQHGDMAFILHALTSLNRSGKAAIVVPHGVLFRGGREAKIREKLINNDVIEGVVDLPSGLLA
GTNIPVSIIILNKLKPEESTEKIFMVNAKDIEHKGFELPREDLDMIIEAYIRKDTIDGFSMWINREDIIDHSLLVKNYFE
DCEVTTPIGKFEIDRKDYENNTETVSLKSLGTFYRGLNTHAYKTQKSESPTHKILQLSNVENGEIFLENADSYNAKELKN
PSSYEVQPGDVIISSRGNSIKIAVIPEEIENTLLSHNFIGFRPNDNVDPYFIKYFMESPIGIKYLSLYQKGSAVSVLKVK
DIEKIYIPKVSLEEQKAISNKLRNADLTLQRKIQKAKEEHKQLYLYAYRSLGIHESITEKK

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=365, Percent_Identity=21.9178082191781, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 70849; Mature: 70849

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHKHIFQLCEHLRGELQPEEYLDVIFPVLTIKHISETKSPYYIPEDATWNCLIASGLNL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEHHHHHHH
VKRVEKAIELIEGNNYRLNNVLNIFPGKSLSDVNLYNFMLGIDEIQDHKQFLKTVIDHFS
HHHHHHHHHHHCCCCEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRIGKASGVWHTSNTLNELIVRLIAPMDGSFYDGTAGLCNTLIEASEFAEQEGGALQLYG
HHHCCCCCCEECHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
QEIDPKIWALGKINLIFNECHDVVLEREDSLRNPMTTEDNNLKTFDYIGMNIPFGLRDWG
CCCCCCEEEEEEEHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCC
VEEARRDLFGRFRYGIPSKQHGDMAFILHALTSLNRSGKAAIVVPHGVLFRGGREAKIRE
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCHHHHH
KLINNDVIEGVVDLPSGLLAGTNIPVSIIILNKLKPEESTEKIFMVNAKDIEHKGFELPR
HHHCCHHHHHHHHCCCCCEECCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCH
EDLDMIIEAYIRKDTIDGFSMWINREDIIDHSLLVKNYFEDCEVTTPIGKFEIDRKDYEN
HHHHHHHHHHHHHCCCCHHHHEECHHHHHHHHHHHHHHHHCCCEECCCCCEEECCCCCCC
NTETVSLKSLGTFYRGLNTHAYKTQKSESPTHKILQLSNVENGEIFLENADSYNAKELKN
CCCEEEHHHHHHHHHCCCCCCCCCCCCCCCHHHHEEECCCCCCEEEEECCCCCCHHHCCC
PSSYEVQPGDVIISSRGNSIKIAVIPEEIENTLLSHNFIGFRPNDNVDPYFIKYFMESPI
CCCCCCCCCCEEEECCCCEEEEEEECHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCC
GIKYLSLYQKGSAVSVLKVKDIEKIYIPKVSLEEQKAISNKLRNADLTLQRKIQKAKEEH
CEEEHHHHCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KQLYLYAYRSLGIHESITEKK
HHEEEEEEHHCCCCCHHCCCC
>Mature Secondary Structure
MEHKHIFQLCEHLRGELQPEEYLDVIFPVLTIKHISETKSPYYIPEDATWNCLIASGLNL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEHHHHHHH
VKRVEKAIELIEGNNYRLNNVLNIFPGKSLSDVNLYNFMLGIDEIQDHKQFLKTVIDHFS
HHHHHHHHHHHCCCCEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRIGKASGVWHTSNTLNELIVRLIAPMDGSFYDGTAGLCNTLIEASEFAEQEGGALQLYG
HHHCCCCCCEECHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
QEIDPKIWALGKINLIFNECHDVVLEREDSLRNPMTTEDNNLKTFDYIGMNIPFGLRDWG
CCCCCCEEEEEEEHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCC
VEEARRDLFGRFRYGIPSKQHGDMAFILHALTSLNRSGKAAIVVPHGVLFRGGREAKIRE
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCHHHHH
KLINNDVIEGVVDLPSGLLAGTNIPVSIIILNKLKPEESTEKIFMVNAKDIEHKGFELPR
HHHCCHHHHHHHHCCCCCEECCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCH
EDLDMIIEAYIRKDTIDGFSMWINREDIIDHSLLVKNYFEDCEVTTPIGKFEIDRKDYEN
HHHHHHHHHHHHHCCCCHHHHEECHHHHHHHHHHHHHHHHCCCEECCCCCEEECCCCCCC
NTETVSLKSLGTFYRGLNTHAYKTQKSESPTHKILQLSNVENGEIFLENADSYNAKELKN
CCCEEEHHHHHHHHHCCCCCCCCCCCCCCCHHHHEEECCCCCCEEEEECCCCCCHHHCCC
PSSYEVQPGDVIISSRGNSIKIAVIPEEIENTLLSHNFIGFRPNDNVDPYFIKYFMESPI
CCCCCCCCCCEEEECCCCEEEEEEECHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCC
GIKYLSLYQKGSAVSVLKVKDIEKIYIPKVSLEEQKAISNKLRNADLTLQRKIQKAKEEH
CEEEHHHHCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KQLYLYAYRSLGIHESITEKK
HHEEEEEEHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]