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The map label for this gene is arsR [C]

Identifier: 188585387

GI number: 188585387

Start: 784350

End: 784709

Strand: Direct

Name: arsR [C]

Synonym: Nther_0754

Alternate gene names: 188585387

Gene position: 784350-784709 (Clockwise)

Preceding gene: 188585386

Following gene: 188585388

Centisome position: 24.78

GC content: 33.89

Gene sequence:

>360_bases
ATGAACGAAAAAAAGATTTTTAAAGTGTTTAAAGCTTTAGGTGAACCCAGCCGTTTAAAAATAATAAAACTACTATCCCA
ACAGAGTATGTGTGTGTGCGAATTGAGTGAAGTATTAGATATGAGCCAGCCCAGAGTATCTCAACATTTGCGTACATTAA
AAGAAGTGGACTTAGTCTATGAAGAGCGCCAAGGATTTTGGACCTATTACAAATTAGATCTTGATGAAATGCATAAAGTA
TTAAAAGAATTTCATGACTTTCTTGGAGCGGACCTTAACGAAATAGAAGGTTACGAAGAAATTCACCATCGTTTGGTAAA
TCTTCCTCCTAAGGAAGAGATAAAGAATAAAACTAAATAA

Upstream 100 bases:

>100_bases
AGTTAATTGTTGATAACAGTTCGAATGAAATGTTATTAATCAACAGTCAACTAACCAGTTATCCTTTAAATCAACTTAAA
TTAGTTAGGGGTGGACAGGA

Downstream 100 bases:

>100_bases
TGTACTAGGGTGTGGGTTATTTAGATTCCGGCTAGACGGTAAGTATATGATATGATCATATGCTTGCCGTATTTTTAATT
TGTGACACTTTCAGCAAACA

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MNEKKIFKVFKALGEPSRLKIIKLLSQQSMCVCELSEVLDMSQPRVSQHLRTLKEVDLVYEERQGFWTYYKLDLDEMHKV
LKEFHDFLGADLNEIEGYEEIHHRLVNLPPKEEIKNKTK

Sequences:

>Translated_119_residues
MNEKKIFKVFKALGEPSRLKIIKLLSQQSMCVCELSEVLDMSQPRVSQHLRTLKEVDLVYEERQGFWTYYKLDLDEMHKV
LKEFHDFLGADLNEIEGYEEIHHRLVNLPPKEEIKNKTK
>Mature_119_residues
MNEKKIFKVFKALGEPSRLKIIKLLSQQSMCVCELSEVLDMSQPRVSQHLRTLKEVDLVYEERQGFWTYYKLDLDEMHKV
LKEFHDFLGADLNEIEGYEEIHHRLVNLPPKEEIKNKTK

Specific function: Transcriptional Repressor For The Arsefg Operon. Arse Is A Trans-Acting Regulatory Protein Which Controls Its Own Expression. The Repressive Effect Of Arse Is Alleviated By Oxyions Of +III Oxidation State Of Arsenic, Antimony, And Bismuth, As Well As Arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=68, Percent_Identity=42.6470588235294, Blast_Score=64, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 14177; Mature: 14177

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKKIFKVFKALGEPSRLKIIKLLSQQSMCVCELSEVLDMSQPRVSQHLRTLKEVDLVY
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EERQGFWTYYKLDLDEMHKVLKEFHDFLGADLNEIEGYEEIHHRLVNLPPKEEIKNKTK
HHHCCCCHHEECCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCHHHHCCCCC
>Mature Secondary Structure
MNEKKIFKVFKALGEPSRLKIIKLLSQQSMCVCELSEVLDMSQPRVSQHLRTLKEVDLVY
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EERQGFWTYYKLDLDEMHKVLKEFHDFLGADLNEIEGYEEIHHRLVNLPPKEEIKNKTK
HHHCCCCHHEECCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]