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The map label for this gene is pbpG [H]

Identifier: 188585372

GI number: 188585372

Start: 767099

End: 769105

Strand: Reverse

Name: pbpG [H]

Synonym: Nther_0739

Alternate gene names: 188585372

Gene position: 769105-767099 (Counterclockwise)

Preceding gene: 188585375

Following gene: 188585370

Centisome position: 24.3

GC content: 41.8

Gene sequence:

>2007_bases
ATGAAATTCAAGTGGTCACAACTAGTTATAACTTTACTGATTATAATAGCAGTCTTAATAAGTGGTGGTTTAGGTTTTTT
TACCTATATGGTATTTAGCATGGAAGAACTGCCAGATAGCCAACAGGCTCAAACCTCTCGCTTCTACTATCATGATGGTG
AACTGATGACTACCCAGTTTGTTGAAAACCGGACCAAAGTCCCTCTAGAAGAAATATCAGAACAGGTTGTCTGGGCAACC
GTGGCCGTGGAAGATAGTGATTTTTACAGTCACAGTGGTTTTGATTTCACGGGAATTGCCAGGGCTGCTTATCAAAATTT
AAGGGAAAGGCGAATAACACAAGGTGGCAGTACCATTACCCAGCAACTGGCTAAAAACCTTTACTTAAATCATGATAGGA
CTTGGGATAGGAAACTGGAAGAAGCTGCTATAGCAATTAATTTAGAACGTAAGTTTTCCAAAGATGAAATCATGGAAAAA
TACTTAAACACTATCTATTACGGCCATTCAACTTACGGTATAGAGGCGGCTTCTCAGCTGTATTTTGACAAGCCAGCAGA
CGAACTCAATACGGCAGAAGCTGCTATGTTAGCTGGGATTCCTAGGGGTCCTGGATATTATTCTCCTTTCATCAATGAAG
AATCTGCCTATAATCGACAGCGCATTATCTTAAAATTGATGGAGGAAGAAGGATTTATAAGTCCCAGTGAGCTAGAGCAG
GCTTTGAATGAGGAACTGGAGTTGAATGAAGAGTTCGCTTTACCTCGAGAAAGTAACTACGTGGTGGAGCAAATTATGAA
TCAAGAACTTGATGAGATCACCGAAGATGATCCAGAAACAATTCAAAAAGGAGGATTTGATTTTCACACAACCATAGATC
CTCACATGCAGGAAGTGGCAGAACGGATTCTAGACGAAGAATTACCTGAAACAAGTAAGGACGAGGAAGGTACTAAACAA
CCACAAGGAGCTTTAGTGGCTTTAGAACCCGATACCGGTAAGATAAGGGCCCTGGTAGGAGGTAGGGACTATCAGGAAAC
TATGTTGAACCGGGTGAATATATCCAGATCACCGGGGTCTGCCTTTAAACCCCTAGTATATGCCGCTGCCCTAGAACAAG
ATTATACCATAGCAGACACTTTTCTTTGTGAACCTATCTCTCTTCAAGAGGAAGGCATGGACGAACCCTATGAGCCTACT
GATTTTGATGGGGGATTTCATGATGAGAATTTGACCTTGAGAAGAGCTCTAGCCGAATCTTGCAATATTACAGCAGTAAA
GTTGAATCAGAAGATCGGAAGGGACGCTGCCGCAGAAATGGCAGATAGGTTGGGAGTTGAAAGTTCTATCGGTAACCATT
TGTCAACGCCTCTGGGTAGTTCAGAAGTCAATTTATTAGAACTAACTGCTGCCTACGCACCATTTGCAAATGGTGGCTAC
CGTATAGAACCTGTTATACTCAATCAAGCCACAGATCATAACAATGAAGAATTGATAAATAACTCTGCAGAAAAAGAAAA
AGTAATTGACGAAGGTATAGCTTATCTCATGACAGATATGATGAAAGACGCACTAGAACCAGGAGGTACCGCTGAAAGGG
TATCTCAAATTTTAGAGAGGCCTGGGGCTGGTAAAACCGGAACTTCTCAAGGCTTTAGAGATGCCTATATGGTCGGATAT
ACACCTGATCTGGTTGTAGGAATATATATCGGTAATGATCAAGAAGAGCCACTACAGGGTACGGGAGGCAGTCTGGCCGC
ACCAATATGGGCTAAATTTGTAGAAGAGGCATCTCATGCTATACCTCCTAAGGATTTTACCAGACCGGATAATGTAGTGA
CAGAAACTATTTGTCAGGAAACCGGTCTAATCCAATCAGAATATTGTACTGCTGATAGTGAAAAAGAGCTATTTATTGAA
GGAACTGCACCTGCAGAAGACTGTTCTTACCAAGATTGTCCCTACATTGAAGAACCCAATTGGTGGGAGTGGGATTTTTG
GTTCTAA

Upstream 100 bases:

>100_bases
ACCTTACTTTTAGCTTAACTTTATAGTAAAATAAATGAGTACGTGACAAGTGAACCAATATTAGTTGCTTGTAGTTAATA
TTTGATAAAGGATGATGTAT

Downstream 100 bases:

>100_bases
GCATTGTTTAAGTTCGCAATCACTTTGGGACTTTTCCAACATTTTAAATGTTATACTGATAATTGATAGATTTGAGAACT
TGCAATTTATTTTTATAAAA

Product: penicillin-binding protein, 1A family

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MKFKWSQLVITLLIIIAVLISGGLGFFTYMVFSMEELPDSQQAQTSRFYYHDGELMTTQFVENRTKVPLEEISEQVVWAT
VAVEDSDFYSHSGFDFTGIARAAYQNLRERRITQGGSTITQQLAKNLYLNHDRTWDRKLEEAAIAINLERKFSKDEIMEK
YLNTIYYGHSTYGIEAASQLYFDKPADELNTAEAAMLAGIPRGPGYYSPFINEESAYNRQRIILKLMEEEGFISPSELEQ
ALNEELELNEEFALPRESNYVVEQIMNQELDEITEDDPETIQKGGFDFHTTIDPHMQEVAERILDEELPETSKDEEGTKQ
PQGALVALEPDTGKIRALVGGRDYQETMLNRVNISRSPGSAFKPLVYAAALEQDYTIADTFLCEPISLQEEGMDEPYEPT
DFDGGFHDENLTLRRALAESCNITAVKLNQKIGRDAAAEMADRLGVESSIGNHLSTPLGSSEVNLLELTAAYAPFANGGY
RIEPVILNQATDHNNEELINNSAEKEKVIDEGIAYLMTDMMKDALEPGGTAERVSQILERPGAGKTGTSQGFRDAYMVGY
TPDLVVGIYIGNDQEEPLQGTGGSLAAPIWAKFVEEASHAIPPKDFTRPDNVVTETICQETGLIQSEYCTADSEKELFIE
GTAPAEDCSYQDCPYIEEPNWWEWDFWF

Sequences:

>Translated_668_residues
MKFKWSQLVITLLIIIAVLISGGLGFFTYMVFSMEELPDSQQAQTSRFYYHDGELMTTQFVENRTKVPLEEISEQVVWAT
VAVEDSDFYSHSGFDFTGIARAAYQNLRERRITQGGSTITQQLAKNLYLNHDRTWDRKLEEAAIAINLERKFSKDEIMEK
YLNTIYYGHSTYGIEAASQLYFDKPADELNTAEAAMLAGIPRGPGYYSPFINEESAYNRQRIILKLMEEEGFISPSELEQ
ALNEELELNEEFALPRESNYVVEQIMNQELDEITEDDPETIQKGGFDFHTTIDPHMQEVAERILDEELPETSKDEEGTKQ
PQGALVALEPDTGKIRALVGGRDYQETMLNRVNISRSPGSAFKPLVYAAALEQDYTIADTFLCEPISLQEEGMDEPYEPT
DFDGGFHDENLTLRRALAESCNITAVKLNQKIGRDAAAEMADRLGVESSIGNHLSTPLGSSEVNLLELTAAYAPFANGGY
RIEPVILNQATDHNNEELINNSAEKEKVIDEGIAYLMTDMMKDALEPGGTAERVSQILERPGAGKTGTSQGFRDAYMVGY
TPDLVVGIYIGNDQEEPLQGTGGSLAAPIWAKFVEEASHAIPPKDFTRPDNVVTETICQETGLIQSEYCTADSEKELFIE
GTAPAEDCSYQDCPYIEEPNWWEWDFWF
>Mature_668_residues
MKFKWSQLVITLLIIIAVLISGGLGFFTYMVFSMEELPDSQQAQTSRFYYHDGELMTTQFVENRTKVPLEEISEQVVWAT
VAVEDSDFYSHSGFDFTGIARAAYQNLRERRITQGGSTITQQLAKNLYLNHDRTWDRKLEEAAIAINLERKFSKDEIMEK
YLNTIYYGHSTYGIEAASQLYFDKPADELNTAEAAMLAGIPRGPGYYSPFINEESAYNRQRIILKLMEEEGFISPSELEQ
ALNEELELNEEFALPRESNYVVEQIMNQELDEITEDDPETIQKGGFDFHTTIDPHMQEVAERILDEELPETSKDEEGTKQ
PQGALVALEPDTGKIRALVGGRDYQETMLNRVNISRSPGSAFKPLVYAAALEQDYTIADTFLCEPISLQEEGMDEPYEPT
DFDGGFHDENLTLRRALAESCNITAVKLNQKIGRDAAAEMADRLGVESSIGNHLSTPLGSSEVNLLELTAAYAPFANGGY
RIEPVILNQATDHNNEELINNSAEKEKVIDEGIAYLMTDMMKDALEPGGTAERVSQILERPGAGKTGTSQGFRDAYMVGY
TPDLVVGIYIGNDQEEPLQGTGGSLAAPIWAKFVEEASHAIPPKDFTRPDNVVTETICQETGLIQSEYCTADSEKELFIE
GTAPAEDCSYQDCPYIEEPNWWEWDFWF

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=579, Percent_Identity=28.3246977547496, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1788867, Length=583, Percent_Identity=28.8164665523156, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI87082258, Length=306, Percent_Identity=34.640522875817, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1789601, Length=230, Percent_Identity=33.9130434782609, Blast_Score=125, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.2.-; 3.4.-.-

Molecular weight: Translated: 75005; Mature: 75005

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKWSQLVITLLIIIAVLISGGLGFFTYMVFSMEELPDSQQAQTSRFYYHDGELMTTQF
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHCCEEEECCCEEEHHH
VENRTKVPLEEISEQVVWATVAVEDSDFYSHSGFDFTGIARAAYQNLRERRITQGGSTIT
HHCCCCCCHHHHCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
QQLAKNLYLNHDRTWDRKLEEAAIAINLERKFSKDEIMEKYLNTIYYGHSTYGIEAASQL
HHHHHHHCCCCCCCHHHHHHHHHEEEEEHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
YFDKPADELNTAEAAMLAGIPRGPGYYSPFINEESAYNRQRIILKLMEEEGFISPSELEQ
HCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALNEELELNEEFALPRESNYVVEQIMNQELDEITEDDPETIQKGGFDFHTTIDPHMQEVA
HHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCEEECCCCHHHHHHH
ERILDEELPETSKDEEGTKQPQGALVALEPDTGKIRALVGGRDYQETMLNRVNISRSPGS
HHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHCCCCCCCC
AFKPLVYAAALEQDYTIADTFLCEPISLQEEGMDEPYEPTDFDGGFHDENLTLRRALAES
HHHHHHHHHHHCCCCEEHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
CNITAVKLNQKIGRDAAAEMADRLGVESSIGNHLSTPLGSSEVNLLELTAAYAPFANGGY
CCEEEEEECHHHCHHHHHHHHHHCCCHHHHCCHHCCCCCCCCCHHEEHHHHHCCCCCCCE
RIEPVILNQATDHNNEELINNSAEKEKVIDEGIAYLMTDMMKDALEPGGTAERVSQILER
EEEEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
PGAGKTGTSQGFRDAYMVGYTPDLVVGIYIGNDQEEPLQGTGGSLAAPIWAKFVEEASHA
CCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
IPPKDFTRPDNVVTETICQETGLIQSEYCTADSEKELFIEGTAPAEDCSYQDCPYIEEPN
CCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
WWEWDFWF
CEEECCCC
>Mature Secondary Structure
MKFKWSQLVITLLIIIAVLISGGLGFFTYMVFSMEELPDSQQAQTSRFYYHDGELMTTQF
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHCCEEEECCCEEEHHH
VENRTKVPLEEISEQVVWATVAVEDSDFYSHSGFDFTGIARAAYQNLRERRITQGGSTIT
HHCCCCCCHHHHCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
QQLAKNLYLNHDRTWDRKLEEAAIAINLERKFSKDEIMEKYLNTIYYGHSTYGIEAASQL
HHHHHHHCCCCCCCHHHHHHHHHEEEEEHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
YFDKPADELNTAEAAMLAGIPRGPGYYSPFINEESAYNRQRIILKLMEEEGFISPSELEQ
HCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALNEELELNEEFALPRESNYVVEQIMNQELDEITEDDPETIQKGGFDFHTTIDPHMQEVA
HHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCEEECCCCHHHHHHH
ERILDEELPETSKDEEGTKQPQGALVALEPDTGKIRALVGGRDYQETMLNRVNISRSPGS
HHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHCCCCCCCC
AFKPLVYAAALEQDYTIADTFLCEPISLQEEGMDEPYEPTDFDGGFHDENLTLRRALAES
HHHHHHHHHHHCCCCEEHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
CNITAVKLNQKIGRDAAAEMADRLGVESSIGNHLSTPLGSSEVNLLELTAAYAPFANGGY
CCEEEEEECHHHCHHHHHHHHHHCCCHHHHCCHHCCCCCCCCCHHEEHHHHHCCCCCCCE
RIEPVILNQATDHNNEELINNSAEKEKVIDEGIAYLMTDMMKDALEPGGTAERVSQILER
EEEEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
PGAGKTGTSQGFRDAYMVGYTPDLVVGIYIGNDQEEPLQGTGGSLAAPIWAKFVEEASHA
CCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
IPPKDFTRPDNVVTETICQETGLIQSEYCTADSEKELFIEGTAPAEDCSYQDCPYIEEPN
CCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
WWEWDFWF
CEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]