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The map label for this gene is 188585345

Identifier: 188585345

GI number: 188585345

Start: 736293

End: 736889

Strand: Direct

Name: 188585345

Synonym: Nther_0710

Alternate gene names: NA

Gene position: 736293-736889 (Clockwise)

Preceding gene: 188585344

Following gene: 188585347

Centisome position: 23.26

GC content: 36.68

Gene sequence:

>597_bases
GTGAAATTAGATTATGAATTTTTTCAAAGAGACGCCGTATCAGTAGCAAAGGATTTAATAGGGAAGTTACTTGTTAGAAA
TCTCAATGGGGAAGAATTGATTTGCAGGATAGTAGATACAGAAGCCTATTGTGGACCAGAAGATAAAGGCTGCCATGCTT
ATCAAAACAAGCGGACAAATCGTACTGAAGTTATGTACAAATCCGGCGGTTATGTCTATGTTTATCTTATTTATGGTTTA
CATTATTGTTTCAATGTAGTAGTCAGTAAACAAGACAGGCCAGAGGCGGTGTTTATTAGGGCTGGTGAGCCTATTTCAGG
CCTTAAAACCATGAGAGATAATAGAAATATCAAATCCAATAAAAAAACTGAACTGACAAATGGCCCCGGGAAACTGTCCC
AGGCTATGGCAATAGATAAATCCTTGAATGGCCAAGATCTAGTTGCCAGTAAGGAAATCTATCTTAGACATGCTTGTGAT
TCACAGAGCTATCAAATTATTCCTGCTAAAAGAGTGAATATCGATTATGCCGAAGAATATACAGACAAACTCTGGAGGTT
TTATATCCGAGATAATCCTTTTGTTTCAATAAATTAA

Upstream 100 bases:

>100_bases
CAACTGCTGTGATTTTGGTGAAGGAAGAAGAAGTTAAAAATGCCTATGAGATAATCGAAAGGCATTAGCAATTAGCAAAT
GCTAGTTGGGAGTGAGGATA

Downstream 100 bases:

>100_bases
TCCCATTTTAGTTATTATTCATTCCCTAGTTGTCAGATCATCCCAGATTGTTATCCGGGTTTTTTCCTTGTATTTTATCT
TTTCCTTCTCCAATAAAGAA

Product: DNA-3-methyladenine glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKLDYEFFQRDAVSVAKDLIGKLLVRNLNGEELICRIVDTEAYCGPEDKGCHAYQNKRTNRTEVMYKSGGYVYVYLIYGL
HYCFNVVVSKQDRPEAVFIRAGEPISGLKTMRDNRNIKSNKKTELTNGPGKLSQAMAIDKSLNGQDLVASKEIYLRHACD
SQSYQIIPAKRVNIDYAEEYTDKLWRFYIRDNPFVSIN

Sequences:

>Translated_198_residues
MKLDYEFFQRDAVSVAKDLIGKLLVRNLNGEELICRIVDTEAYCGPEDKGCHAYQNKRTNRTEVMYKSGGYVYVYLIYGL
HYCFNVVVSKQDRPEAVFIRAGEPISGLKTMRDNRNIKSNKKTELTNGPGKLSQAMAIDKSLNGQDLVASKEIYLRHACD
SQSYQIIPAKRVNIDYAEEYTDKLWRFYIRDNPFVSIN
>Mature_198_residues
MKLDYEFFQRDAVSVAKDLIGKLLVRNLNGEELICRIVDTEAYCGPEDKGCHAYQNKRTNRTEVMYKSGGYVYVYLIYGL
HYCFNVVVSKQDRPEAVFIRAGEPISGLKTMRDNRNIKSNKKTELTNGPGKLSQAMAIDKSLNGQDLVASKEIYLRHACD
SQSYQIIPAKRVNIDYAEEYTDKLWRFYIRDNPFVSIN

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=205, Percent_Identity=40.4878048780488, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI62632771, Length=205, Percent_Identity=40.4878048780488, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI62632765, Length=205, Percent_Identity=40.4878048780488, Blast_Score=145, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_NATTJ (B2A7A8)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001916890.1
- ProteinModelPortal:   B2A7A8
- SMR:   B2A7A8
- GeneID:   6316424
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_0710
- HOGENOM:   HBG664239
- OMA:   EHISSQY
- ProtClustDB:   CLSK2802373
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: NA

Molecular weight: Translated: 22786; Mature: 22786

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDYEFFQRDAVSVAKDLIGKLLVRNLNGEELICRIVDTEAYCGPEDKGCHAYQNKRTN
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHCCCCC
RTEVMYKSGGYVYVYLIYGLHYCFNVVVSKQDRPEAVFIRAGEPISGLKTMRDNRNIKSN
CEEEEEECCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCC
KKTELTNGPGKLSQAMAIDKSLNGQDLVASKEIYLRHACDSQSYQIIPAKRVNIDYAEEY
CCCCCCCCCCHHHHHHHHHCCCCCCCCEEHHHEEEEECCCCCCEEEEECEECCCCHHHHH
TDKLWRFYIRDNPFVSIN
HHHHHEEEECCCCEEEEC
>Mature Secondary Structure
MKLDYEFFQRDAVSVAKDLIGKLLVRNLNGEELICRIVDTEAYCGPEDKGCHAYQNKRTN
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHCCCCC
RTEVMYKSGGYVYVYLIYGLHYCFNVVVSKQDRPEAVFIRAGEPISGLKTMRDNRNIKSN
CEEEEEECCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCC
KKTELTNGPGKLSQAMAIDKSLNGQDLVASKEIYLRHACDSQSYQIIPAKRVNIDYAEEY
CCCCCCCCCCHHHHHHHHHCCCCCCCCEEHHHEEEEECCCCCCEEEEECEECCCCHHHHH
TDKLWRFYIRDNPFVSIN
HHHHHEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA