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The map label for this gene is vanW [H]

Identifier: 188585236

GI number: 188585236

Start: 622605

End: 623411

Strand: Direct

Name: vanW [H]

Synonym: Nther_0598

Alternate gene names: 188585236

Gene position: 622605-623411 (Clockwise)

Preceding gene: 188585235

Following gene: 188585237

Centisome position: 19.67

GC content: 36.56

Gene sequence:

>807_bases
ATGAAAACATCGATACAAAGATCCAAACTACGTCTGCTTTTGGGAAAGTTCTACTATCAAATTAAACGATACCTGGAATG
GTATTTAAGTACCACTAAGTGGGCAAGTATGTATAAAGATAAGCTTTTAAAGTATTCAGTTTTTCAACATAAAACACCCT
TACTGAGAAAGCTAAGTCAAGTGGAAATGTGGATGCAATATAATAAAATTACTAATTTAGAAATAGCTACTAAGAGATTA
AACAAAATTATCATTAAACCAGGAGAAACTTTTTCTTATTGGAGACTAATCGGAAGACCCACCAGGACTAAAGGTTATCT
AGAGGGTATGGTGTTATACAATGGGAAAGTAGAGTCGGGTGTAGGCGGTGGACTGTGTCAGCTTTCCAATTTAATCTATT
GGATGACTCTCCACACTCCCCTGACAGTTACCGAAAGGTACCGACACAGTTACGATGTTTTTCCGGATTCCAATCGAACT
GTGCCCTTTGGGAGTGGAGCCACTTGTGCCTATAATTATATAGATTTGCAAATATATAATGGGACTAAACAAACATATCA
ATTGCTTGTGTACTTGACTGATGATTACTTGGTGGGAGAGTGGAGGTCTGATAATGAACCATGTCATACATATGAGGTGT
ATCAGGGGGATCACTGGATAACCCATGAACCTGGTATCGGGTATGTACGTCATAATACAATATATCGAAAAGTTTATAAT
CTTAAAGGAGAAGATATTGATGATGAATTTGTTACAGAAAATCATGCTATTATGATGTATCAACCCTATTTAGAACAGGG
AGATTAG

Upstream 100 bases:

>100_bases
TAAAAAGTCGGATATAATTTCCGGGATATTATTAGTATTTTTAGCTTTTGCTATACTACTAACACCTTTATAATTATTAT
AAATTCAGGGGGAGGGGATT

Downstream 100 bases:

>100_bases
GAAAAAGTGCTTAATATAAGATCAGCAAATATAATACTGTTATTGAGCCCTGAAGTTATCAATAACGAAATAACAGCACT
AATCTAAAAAAGTTGGTTGT

Product: VanW family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKTSIQRSKLRLLLGKFYYQIKRYLEWYLSTTKWASMYKDKLLKYSVFQHKTPLLRKLSQVEMWMQYNKITNLEIATKRL
NKIIIKPGETFSYWRLIGRPTRTKGYLEGMVLYNGKVESGVGGGLCQLSNLIYWMTLHTPLTVTERYRHSYDVFPDSNRT
VPFGSGATCAYNYIDLQIYNGTKQTYQLLVYLTDDYLVGEWRSDNEPCHTYEVYQGDHWITHEPGIGYVRHNTIYRKVYN
LKGEDIDDEFVTENHAIMMYQPYLEQGD

Sequences:

>Translated_268_residues
MKTSIQRSKLRLLLGKFYYQIKRYLEWYLSTTKWASMYKDKLLKYSVFQHKTPLLRKLSQVEMWMQYNKITNLEIATKRL
NKIIIKPGETFSYWRLIGRPTRTKGYLEGMVLYNGKVESGVGGGLCQLSNLIYWMTLHTPLTVTERYRHSYDVFPDSNRT
VPFGSGATCAYNYIDLQIYNGTKQTYQLLVYLTDDYLVGEWRSDNEPCHTYEVYQGDHWITHEPGIGYVRHNTIYRKVYN
LKGEDIDDEFVTENHAIMMYQPYLEQGD
>Mature_268_residues
MKTSIQRSKLRLLLGKFYYQIKRYLEWYLSTTKWASMYKDKLLKYSVFQHKTPLLRKLSQVEMWMQYNKITNLEIATKRL
NKIIIKPGETFSYWRLIGRPTRTKGYLEGMVLYNGKVESGVGGGLCQLSNLIYWMTLHTPLTVTERYRHSYDVFPDSNRT
VPFGSGATCAYNYIDLQIYNGTKQTYQLLVYLTDDYLVGEWRSDNEPCHTYEVYQGDHWITHEPGIGYVRHNTIYRKVYN
LKGEDIDDEFVTENHAIMMYQPYLEQGD

Specific function: Unknown

COG id: COG2720

COG function: function code V; Uncharacterized vancomycin resistance protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007391 [H]

Pfam domain/function: PF04294 VanW [H]

EC number: NA

Molecular weight: Translated: 31787; Mature: 31787

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSIQRSKLRLLLGKFYYQIKRYLEWYLSTTKWASMYKDKLLKYSVFQHKTPLLRKLSQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VEMWMQYNKITNLEIATKRLNKIIIKPGETFSYWRLIGRPTRTKGYLEGMVLYNGKVESG
HHHHHHHCCCCCHHHHHHHHCEEEECCCCCCHHHHHHCCCCCCCHHEEEEEEECCEECCC
VGGGLCQLSNLIYWMTLHTPLTVTERYRHSYDVFPDSNRTVPFGSGATCAYNYIDLQIYN
CCCCHHHHCCEEEEEEECCCEEHHHHHCCCCCCCCCCCCEEECCCCCEEEEEEEEEEEEC
GTKQTYQLLVYLTDDYLVGEWRSDNEPCHTYEVYQGDHWITHEPGIGYVRHNTIYRKVYN
CCHHHEEEEEEEECCEEEECCCCCCCCCEEEEEEECCEEEECCCCCCEEEHHHHHHHHHC
LKGEDIDDEFVTENHAIMMYQPYLEQGD
CCCCCCCHHHHCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKTSIQRSKLRLLLGKFYYQIKRYLEWYLSTTKWASMYKDKLLKYSVFQHKTPLLRKLSQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VEMWMQYNKITNLEIATKRLNKIIIKPGETFSYWRLIGRPTRTKGYLEGMVLYNGKVESG
HHHHHHHCCCCCHHHHHHHHCEEEECCCCCCHHHHHHCCCCCCCHHEEEEEEECCEECCC
VGGGLCQLSNLIYWMTLHTPLTVTERYRHSYDVFPDSNRTVPFGSGATCAYNYIDLQIYN
CCCCHHHHCCEEEEEEECCCEEHHHHHCCCCCCCCCCCCEEECCCCCEEEEEEEEEEEEC
GTKQTYQLLVYLTDDYLVGEWRSDNEPCHTYEVYQGDHWITHEPGIGYVRHNTIYRKVYN
CCHHHEEEEEEEECCEEEECCCCCCCCCEEEEEEECCEEEECCCCCCEEEHHHHHHHHHC
LKGEDIDDEFVTENHAIMMYQPYLEQGD
CCCCCCCHHHHCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631706; 12663927 [H]