Click here to switch to the map view.

The map label for this gene is obg

Identifier: 188585171

GI number: 188585171

Start: 553215

End: 554573

Strand: Direct

Name: obg

Synonym: Nther_0532

Alternate gene names: 188585171

Gene position: 553215-554573 (Clockwise)

Preceding gene: 188585170

Following gene: 188585172

Centisome position: 17.48

GC content: 38.78

Gene sequence:

>1359_bases
ATGTTTATAGATCGAGCGAAAATATACGTAAAAGGTGGAGATGGAGGCAATGGTATAGTTGCTTTTAGGCGCGAAAAATA
CGTGCCTGATGGTGGTCCCAGTGGTGGAGATGGCGGCAAAGGTGGAAACGTAATTTTGGAAGTCGACCCAGGACTCAAAT
CTCTAATGGATTATAAGTATAACATCCATATCAAAGGGAAACGAGGAGAACATGGTCAAGGGAGCAATCAACACGGAAAA
TCTGGTCAGGATAAAGTGATTAAAGTACCACCGGGTACAGTAGTGAAAGAGGCTACTTCAGGAAAAGTTTTAGCTGACTT
AGTTCATGAACATGATAGCTACATAGCTGCTGAAGGTGGCCGAGGGGGAAGAGGGAATACCCGGTTTGCTAATCCCAAAA
ATAAAGCTCCCAGATTCAGTGAGGACGGCAAGCCAGGTGAAGAGAAATGGATTGTACTAGAGTTAAAGGTTATGGCAGAA
GTGGGTTTAATTGGTTATCCCAATGTGGGTAAATCTACTTTATTAAGTCAAGTCACCAAGGCTAGTCCCAAAATTGACAG
TTATCACTTTACCACCCTCAATCCCAATTTGGGTGTAGTTGAATTAGAAGAGGGTAGTAGATTTGTCATGGCAGATATAC
CTGGTCTAATCGAAGGCGCTCATCAAGGAAGAGGATTAGGAGATCAATTTTTAAGGCATATAGAAAGAACGAAAATGTTA
ATTCACGTGATTGATATTGCCTCTATCGAGGGTAGAGATCCTGTTTTAGATATCGAAACAATCAATGAAGAATTAAAGGG
TTATAATAGTAGGGTGATGGATAAACCTCAGGTGATCGCTGCTAATAAAATGGATTTAGGGGATCAGGCAGAAGAAAACC
TCCAAAGATTGCTAGATAAAGTTAATTCAGACGAAATCCTGATACCTGAACAATACAAAAAAATCTTTCCTATCTCGGCT
GCAACTGGAGAAGGGCTGAGGGAATTATTAGATTTTGTGGCAGAAAAAGTAGCACAACTACCTGATACTCATGATACCTT
CGATATTGACTTGGAACTACCTGAATCTGAAGAAAACACTGACACAGAACAAGAAGCTTTATTCACCATGTCTCAAGATG
ATAAAATTGAAGAAAAACCAAAATCAGATTTTGGGATCAGAAAAGAAGGAGATATTTTCATTGTTAAACATGAAAAATTA
GAGAAAATATTAAACGAAATAGATGTTCATACAGAGAAGGGAAGGCATTACTTTCAGGCTAAAGTTGACGAGTTTGGATT
GGAAGAAGCTTTAGTAGATAAAGGAATCAAACCAGGTGATACTGTCAAAATTGGTAATGTAGAATTTGAATATCAGTAA

Upstream 100 bases:

>100_bases
ACTCAAATTTGGATTAAGTTATGTATTTATAAGAACACAGACAAAAGTAGTTTGCAATAAAGATATTTTACGAATCTATT
AAATGAAGGGGTAATCGAAT

Downstream 100 bases:

>100_bases
TTAAACTAGTTAACTTAAATTATCTGTTATAGAGTGGGGGAGTTATATATGGAAAATAATACTTTTAACGCAAGCAGGAT
TGCAATTATGGGTGGCACCT

Product: GTP-binding protein Obg/CgtA

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MFIDRAKIYVKGGDGGNGIVAFRREKYVPDGGPSGGDGGKGGNVILEVDPGLKSLMDYKYNIHIKGKRGEHGQGSNQHGK
SGQDKVIKVPPGTVVKEATSGKVLADLVHEHDSYIAAEGGRGGRGNTRFANPKNKAPRFSEDGKPGEEKWIVLELKVMAE
VGLIGYPNVGKSTLLSQVTKASPKIDSYHFTTLNPNLGVVELEEGSRFVMADIPGLIEGAHQGRGLGDQFLRHIERTKML
IHVIDIASIEGRDPVLDIETINEELKGYNSRVMDKPQVIAANKMDLGDQAEENLQRLLDKVNSDEILIPEQYKKIFPISA
ATGEGLRELLDFVAEKVAQLPDTHDTFDIDLELPESEENTDTEQEALFTMSQDDKIEEKPKSDFGIRKEGDIFIVKHEKL
EKILNEIDVHTEKGRHYFQAKVDEFGLEEALVDKGIKPGDTVKIGNVEFEYQ

Sequences:

>Translated_452_residues
MFIDRAKIYVKGGDGGNGIVAFRREKYVPDGGPSGGDGGKGGNVILEVDPGLKSLMDYKYNIHIKGKRGEHGQGSNQHGK
SGQDKVIKVPPGTVVKEATSGKVLADLVHEHDSYIAAEGGRGGRGNTRFANPKNKAPRFSEDGKPGEEKWIVLELKVMAE
VGLIGYPNVGKSTLLSQVTKASPKIDSYHFTTLNPNLGVVELEEGSRFVMADIPGLIEGAHQGRGLGDQFLRHIERTKML
IHVIDIASIEGRDPVLDIETINEELKGYNSRVMDKPQVIAANKMDLGDQAEENLQRLLDKVNSDEILIPEQYKKIFPISA
ATGEGLRELLDFVAEKVAQLPDTHDTFDIDLELPESEENTDTEQEALFTMSQDDKIEEKPKSDFGIRKEGDIFIVKHEKL
EKILNEIDVHTEKGRHYFQAKVDEFGLEEALVDKGIKPGDTVKIGNVEFEYQ
>Mature_452_residues
MFIDRAKIYVKGGDGGNGIVAFRREKYVPDGGPSGGDGGKGGNVILEVDPGLKSLMDYKYNIHIKGKRGEHGQGSNQHGK
SGQDKVIKVPPGTVVKEATSGKVLADLVHEHDSYIAAEGGRGGRGNTRFANPKNKAPRFSEDGKPGEEKWIVLELKVMAE
VGLIGYPNVGKSTLLSQVTKASPKIDSYHFTTLNPNLGVVELEEGSRFVMADIPGLIEGAHQGRGLGDQFLRHIERTKML
IHVIDIASIEGRDPVLDIETINEELKGYNSRVMDKPQVIAANKMDLGDQAEENLQRLLDKVNSDEILIPEQYKKIFPISA
ATGEGLRELLDFVAEKVAQLPDTHDTFDIDLELPESEENTDTEQEALFTMSQDDKIEEKPKSDFGIRKEGDIFIVKHEKL
EKILNEIDVHTEKGRHYFQAKVDEFGLEEALVDKGIKPGDTVKIGNVEFEYQ

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=329, Percent_Identity=43.4650455927052, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI111955139, Length=397, Percent_Identity=32.9974811083123, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI111955063, Length=299, Percent_Identity=32.7759197324415, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI4557537, Length=160, Percent_Identity=33.75, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI58761500, Length=130, Percent_Identity=35.3846153846154, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI4758796, Length=129, Percent_Identity=34.8837209302326, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1789574, Length=331, Percent_Identity=44.4108761329305, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1787454, Length=129, Percent_Identity=37.984496124031, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790615, Length=181, Percent_Identity=27.6243093922652, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=338, Percent_Identity=39.9408284023669, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17552324, Length=377, Percent_Identity=27.3209549071618, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=141, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=32.2033898305085, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=129, Percent_Identity=32.5581395348837, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=196, Percent_Identity=38.7755102040816, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321649, Length=141, Percent_Identity=31.9148936170213, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319281, Length=130, Percent_Identity=35.3846153846154, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321612, Length=104, Percent_Identity=38.4615384615385, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129375, Length=334, Percent_Identity=39.2215568862275, Blast_Score=188, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24585318, Length=363, Percent_Identity=33.6088154269972, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=34.8837209302326, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=34.8837209302326, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=34.8837209302326, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17981711, Length=129, Percent_Identity=34.1085271317829, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356473, Length=114, Percent_Identity=38.5964912280702, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_NATTJ (B2A6B7)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001916716.1
- ProteinModelPortal:   B2A6B7
- SMR:   B2A6B7
- GeneID:   6314259
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_0532
- HOGENOM:   HBG716038
- OMA:   YIQADEN
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 49908; Mature: 49908

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDRAKIYVKGGDGGNGIVAFRREKYVPDGGPSGGDGGKGGNVILEVDPGLKSLMDYKY
CCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCEE
NIHIKGKRGEHGQGSNQHGKSGQDKVIKVPPGTVVKEATSGKVLADLVHEHDSYIAAEGG
EEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCEECCCCCHHHHHHHHHCCCEEEECCC
RGGRGNTRFANPKNKAPRFSEDGKPGEEKWIVLELKVMAEVGLIGYPNVGKSTLLSQVTK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHCCCCCCCCCCHHHHHHHHHH
ASPKIDSYHFTTLNPNLGVVELEEGSRFVMADIPGLIEGAHQGRGLGDQFLRHIERTKML
CCCCCCCEEEEEECCCCCEEEECCCCEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHE
IHVIDIASIEGRDPVLDIETINEELKGYNSRVMDKPQVIAANKMDLGDQAEENLQRLLDK
EEEEEEEECCCCCCEEEHHHHHHHHCCCCHHCCCCCCEEEECCCCCCHHHHHHHHHHHHH
VNSDEILIPEQYKKIFPISAATGEGLRELLDFVAEKVAQLPDTHDTFDIDLELPESEENT
CCCCCEECCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
DTEQEALFTMSQDDKIEEKPKSDFGIRKEGDIFIVKHEKLEKILNEIDVHTEKGRHYFQA
CCHHHHEEECCCCCCHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCEEEEE
KVDEFGLEEALVDKGIKPGDTVKIGNVEFEYQ
HHHHHCHHHHHHHCCCCCCCEEEECCEEEEEC
>Mature Secondary Structure
MFIDRAKIYVKGGDGGNGIVAFRREKYVPDGGPSGGDGGKGGNVILEVDPGLKSLMDYKY
CCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCEE
NIHIKGKRGEHGQGSNQHGKSGQDKVIKVPPGTVVKEATSGKVLADLVHEHDSYIAAEGG
EEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCEECCCCCHHHHHHHHHCCCEEEECCC
RGGRGNTRFANPKNKAPRFSEDGKPGEEKWIVLELKVMAEVGLIGYPNVGKSTLLSQVTK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHCCCCCCCCCCHHHHHHHHHH
ASPKIDSYHFTTLNPNLGVVELEEGSRFVMADIPGLIEGAHQGRGLGDQFLRHIERTKML
CCCCCCCEEEEEECCCCCEEEECCCCEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHE
IHVIDIASIEGRDPVLDIETINEELKGYNSRVMDKPQVIAANKMDLGDQAEENLQRLLDK
EEEEEEEECCCCCCEEEHHHHHHHHCCCCHHCCCCCCEEEECCCCCCHHHHHHHHHHHHH
VNSDEILIPEQYKKIFPISAATGEGLRELLDFVAEKVAQLPDTHDTFDIDLELPESEENT
CCCCCEECCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
DTEQEALFTMSQDDKIEEKPKSDFGIRKEGDIFIVKHEKLEKILNEIDVHTEKGRHYFQA
CCHHHHEEECCCCCCHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCEEEEE
KVDEFGLEEALVDKGIKPGDTVKIGNVEFEYQ
HHHHHCHHHHHHHCCCCCCCEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA