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The map label for this gene is mrdB [H]

Identifier: 188585161

GI number: 188585161

Start: 544326

End: 545444

Strand: Direct

Name: mrdB [H]

Synonym: Nther_0522

Alternate gene names: 188585161

Gene position: 544326-545444 (Clockwise)

Preceding gene: 188585160

Following gene: 188585162

Centisome position: 17.2

GC content: 34.76

Gene sequence:

>1119_bases
ATGTTTGATAAAAAATTGTTGCGAAATTTTGATTACACGTTATTGATAGTAGTATTACTTATATCAGTTATTGGGGTAAT
TATAATTACAAGTGCTACCCAGCTAAATCCCACGGGTGATTCCTATTATTATACAAGGCGGCAAATTGCTTATATTGCGG
CAGGGTTATTAGTTTTATTAACTATGTTGAGTATTGACTATCATAGCATATTAAGAATAGCTAAACCACTATATATAATC
AATCTGTTATTGCTAACTGCAGTTTTTGTACCAGGATTGGGTAGAGCAGCAGGGGGTGGTGCCCAGCGTTGGTTGAGTTT
AGGTATTATCGATATTCAACCAGCAGAATTTGCCAAAATAATTATAATTATAACTTTAGCTAAATTTTTAGTTGATCAAA
AGAATGGTATTGAAGATATTTACGACTTAATACTTCCTATAGGTCATGTGCTAGTGCCCATGGGTCTGATTTTTTTACAA
CCTGATCTAGGAACTGCCATGGTCTTTATAGCTATTTTATTTGGAGGATTGTTTTTTTATCGAGTTAAATTAAAATTACT
TGGTTATTTAATTGGTGCAGGAATTTTAGTAGGAGTTCCATCTTTTTGGTTATTACTTCATGAATATCAAAGGCAAAGAC
TTATTGTATTTTTGAATCCGTCCAATATTGACCCTTTGGGAGATGGTTTTCACCTATGGCAATCCATGGTGGCAATTGGT
TCGGGAGGAATTACGGGTAAAGGTCTATTTGAAGGAACTCAAAATAAGTTGGAATTTTTACCAGAAGCTCATACCGATTT
TGTTTTCTCGGTGATTGGTGAGGAATTTGGCCTGATTGGTGCATCCATTGTCTTGTTGTTATTTTTGATTTTAATATACA
GGATTTTAAAAATAGCTTATTTGTCTAAAGACTTTTACGGAACGGTTATTTGTGGAGGAGTGGCTACTATGTTGTTATTC
CAAATGGTAGTGAATGTAGCTATGACTGTTAGTATGATGCCAGTTACTGGCTTACCCCTGCCCTTTATTAGTTATGGGGG
GAGTGGTTATCTGATGAATATGATGGCCATTGGATTAGTTCTTAACGTAGGTATGCGAAGACATAAAATAATGTTCTGA

Upstream 100 bases:

>100_bases
AAAAGTATCAAAAGACAGAAATAGCCCATCTTTTACATAGATGGGCTATTTGATATATAATATATAAAGTAAATAAAATC
GAAGTGGGGTTAGCAGAGAT

Downstream 100 bases:

>100_bases
ATTCAAGTCCTTCTCATGGGGATGTCCCACTTGAGAAGGACTTTTTTAATTCATAAAATATCTCAAGATTTATATACATA
AATATAGAAGGATAGATTCA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MFDKKLLRNFDYTLLIVVLLISVIGVIIITSATQLNPTGDSYYYTRRQIAYIAAGLLVLLTMLSIDYHSILRIAKPLYII
NLLLLTAVFVPGLGRAAGGGAQRWLSLGIIDIQPAEFAKIIIIITLAKFLVDQKNGIEDIYDLILPIGHVLVPMGLIFLQ
PDLGTAMVFIAILFGGLFFYRVKLKLLGYLIGAGILVGVPSFWLLLHEYQRQRLIVFLNPSNIDPLGDGFHLWQSMVAIG
SGGITGKGLFEGTQNKLEFLPEAHTDFVFSVIGEEFGLIGASIVLLLFLILIYRILKIAYLSKDFYGTVICGGVATMLLF
QMVVNVAMTVSMMPVTGLPLPFISYGGSGYLMNMMAIGLVLNVGMRRHKIMF

Sequences:

>Translated_372_residues
MFDKKLLRNFDYTLLIVVLLISVIGVIIITSATQLNPTGDSYYYTRRQIAYIAAGLLVLLTMLSIDYHSILRIAKPLYII
NLLLLTAVFVPGLGRAAGGGAQRWLSLGIIDIQPAEFAKIIIIITLAKFLVDQKNGIEDIYDLILPIGHVLVPMGLIFLQ
PDLGTAMVFIAILFGGLFFYRVKLKLLGYLIGAGILVGVPSFWLLLHEYQRQRLIVFLNPSNIDPLGDGFHLWQSMVAIG
SGGITGKGLFEGTQNKLEFLPEAHTDFVFSVIGEEFGLIGASIVLLLFLILIYRILKIAYLSKDFYGTVICGGVATMLLF
QMVVNVAMTVSMMPVTGLPLPFISYGGSGYLMNMMAIGLVLNVGMRRHKIMF
>Mature_372_residues
MFDKKLLRNFDYTLLIVVLLISVIGVIIITSATQLNPTGDSYYYTRRQIAYIAAGLLVLLTMLSIDYHSILRIAKPLYII
NLLLLTAVFVPGLGRAAGGGAQRWLSLGIIDIQPAEFAKIIIIITLAKFLVDQKNGIEDIYDLILPIGHVLVPMGLIFLQ
PDLGTAMVFIAILFGGLFFYRVKLKLLGYLIGAGILVGVPSFWLLLHEYQRQRLIVFLNPSNIDPLGDGFHLWQSMVAIG
SGGITGKGLFEGTQNKLEFLPEAHTDFVFSVIGEEFGLIGASIVLLLFLILIYRILKIAYLSKDFYGTVICGGVATMLLF
QMVVNVAMTVSMMPVTGLPLPFISYGGSGYLMNMMAIGLVLNVGMRRHKIMF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=364, Percent_Identity=39.010989010989, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1786277, Length=369, Percent_Identity=33.8753387533875, Blast_Score=181, Evalue=9e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41017; Mature: 41017

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDKKLLRNFDYTLLIVVLLISVIGVIIITSATQLNPTGDSYYYTRRQIAYIAAGLLVLL
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TMLSIDYHSILRIAKPLYIINLLLLTAVFVPGLGRAAGGGAQRWLSLGIIDIQPAEFAKI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEECHHHHHHH
IIIITLAKFLVDQKNGIEDIYDLILPIGHVLVPMGLIFLQPDLGTAMVFIAILFGGLFFY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHH
RVKLKLLGYLIGAGILVGVPSFWLLLHEYQRQRLIVFLNPSNIDPLGDGFHLWQSMVAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHC
SGGITGKGLFEGTQNKLEFLPEAHTDFVFSVIGEEFGLIGASIVLLLFLILIYRILKIAY
CCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKDFYGTVICGGVATMLLFQMVVNVAMTVSMMPVTGLPLPFISYGGSGYLMNMMAIGLV
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHH
LNVGMRRHKIMF
HHCCHHHHCCCC
>Mature Secondary Structure
MFDKKLLRNFDYTLLIVVLLISVIGVIIITSATQLNPTGDSYYYTRRQIAYIAAGLLVLL
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TMLSIDYHSILRIAKPLYIINLLLLTAVFVPGLGRAAGGGAQRWLSLGIIDIQPAEFAKI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEECHHHHHHH
IIIITLAKFLVDQKNGIEDIYDLILPIGHVLVPMGLIFLQPDLGTAMVFIAILFGGLFFY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHH
RVKLKLLGYLIGAGILVGVPSFWLLLHEYQRQRLIVFLNPSNIDPLGDGFHLWQSMVAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHC
SGGITGKGLFEGTQNKLEFLPEAHTDFVFSVIGEEFGLIGASIVLLLFLILIYRILKIAY
CCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKDFYGTVICGGVATMLLFQMVVNVAMTVSMMPVTGLPLPFISYGGSGYLMNMMAIGLV
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHH
LNVGMRRHKIMF
HHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]