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The map label for this gene is appB [H]

Identifier: 188585117

GI number: 188585117

Start: 508990

End: 509955

Strand: Direct

Name: appB [H]

Synonym: Nther_0478

Alternate gene names: 188585117

Gene position: 508990-509955 (Clockwise)

Preceding gene: 188585116

Following gene: 188585118

Centisome position: 16.08

GC content: 40.48

Gene sequence:

>966_bases
TTGGGAACTTATATAGTTAGGCGAGTACTGATAATGATCCCTGTGTTACTAGGAATTACTGTCTTTCTCTTTAGCTTGTT
TCAATTAGCACCTGGAAATCCCTTGGCTAGTTTACATCAAGACCCGGATATGACACCAGAAGCTCGAGAGCGTATTGAAG
AACAATACGGATTAAATCAACCCGTACATATACAGTACTTAGATTATATGGGAAATCTATTCCAAGGCGATATGGGTATG
TCGTTTCAGTACAGAAGAGATGTAAGTTTTCTCATAGCTCATAGAATAGGGCCTACTTTTATATTATCATTTGGTGCATT
CTTATTAGCTCTAGTAGTAGCCATACCAGCAGGGATTATATCGGCTACCCGCCAATATACCAGTGTTGATAATGCCTTTA
CGGTGTTTGCCTTAATCGGTGTATCTATTCCTAACTTTTTCTTTGGATTGGTGATGATGCGCGTCTTCGCAGTTGCTCTG
GGGTGGTTCCCCACTGGGGGAATGCAGACCTCTGGAGCGGACTTTCCCTTTCCGTGGAATATATTAGACGTAGCAAATCA
CCTTGTTTTACCTGCTATTGTATTAGGCCTTAGCAGTGCTGCACATTTTATGCGTTACACCAGATCTAGTATGCTAGAAG
TTATCAGACAGGATTATATTCGGACTGCCCGTGCTAAAGGTTTAAAAGAAAGAATCGTTATATACAAACACGCTCTTAGA
AATGCATTGATTCCAATTATCACTTTAATGGGCTTTCAGTTACCCATGCTCTTTTCAGGTTCACTAGTAGTAGAAATTGT
CTTTGGCTGGCCTGGTATGGGAAGGTTGGCTTATAATGCAGTTATGCAGCGTGACTATCCACTAATGATGGGAGTAAACT
TGTTCCTTGCCATATTTATATTACTCGGAAATCTACTAGCTGATATTGCCTATGCCTTTGTAGATCCCAGAATCAGGTAT
GATTAA

Upstream 100 bases:

>100_bases
TAGCTAAGATAGCGAGTACAACCCCATCTGGGCATGTGCCACTCACATGCCCAGATTATTAAAACAATTATTCAGGCTAA
AATAAAGGGGTGATATACTT

Downstream 100 bases:

>100_bases
TTTCTTTAAAAAATAATTTATTTATAATACTTGATATCTGTATGCCTAAAGGGGGGAATGACTTGGCTAAAAATGAACTG
AATGAAAGTACAAGTCAAGA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MGTYIVRRVLIMIPVLLGITVFLFSLFQLAPGNPLASLHQDPDMTPEARERIEEQYGLNQPVHIQYLDYMGNLFQGDMGM
SFQYRRDVSFLIAHRIGPTFILSFGAFLLALVVAIPAGIISATRQYTSVDNAFTVFALIGVSIPNFFFGLVMMRVFAVAL
GWFPTGGMQTSGADFPFPWNILDVANHLVLPAIVLGLSSAAHFMRYTRSSMLEVIRQDYIRTARAKGLKERIVIYKHALR
NALIPIITLMGFQLPMLFSGSLVVEIVFGWPGMGRLAYNAVMQRDYPLMMGVNLFLAIFILLGNLLADIAYAFVDPRIRY
D

Sequences:

>Translated_321_residues
MGTYIVRRVLIMIPVLLGITVFLFSLFQLAPGNPLASLHQDPDMTPEARERIEEQYGLNQPVHIQYLDYMGNLFQGDMGM
SFQYRRDVSFLIAHRIGPTFILSFGAFLLALVVAIPAGIISATRQYTSVDNAFTVFALIGVSIPNFFFGLVMMRVFAVAL
GWFPTGGMQTSGADFPFPWNILDVANHLVLPAIVLGLSSAAHFMRYTRSSMLEVIRQDYIRTARAKGLKERIVIYKHALR
NALIPIITLMGFQLPMLFSGSLVVEIVFGWPGMGRLAYNAVMQRDYPLMMGVNLFLAIFILLGNLLADIAYAFVDPRIRY
D
>Mature_320_residues
GTYIVRRVLIMIPVLLGITVFLFSLFQLAPGNPLASLHQDPDMTPEARERIEEQYGLNQPVHIQYLDYMGNLFQGDMGMS
FQYRRDVSFLIAHRIGPTFILSFGAFLLALVVAIPAGIISATRQYTSVDNAFTVFALIGVSIPNFFFGLVMMRVFAVALG
WFPTGGMQTSGADFPFPWNILDVANHLVLPAIVLGLSSAAHFMRYTRSSMLEVIRQDYIRTARAKGLKERIVIYKHALRN
ALIPIITLMGFQLPMLFSGSLVVEIVFGWPGMGRLAYNAVMQRDYPLMMGVNLFLAIFILLGNLLADIAYAFVDPRIRYD

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=321, Percent_Identity=39.2523364485981, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1789965, Length=335, Percent_Identity=36.7164179104478, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1787497, Length=321, Percent_Identity=36.4485981308411, Blast_Score=212, Evalue=2e-56,
Organism=Escherichia coli, GI1789888, Length=324, Percent_Identity=32.4074074074074, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI1788504, Length=365, Percent_Identity=30.958904109589, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1787761, Length=327, Percent_Identity=35.474006116208, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1787550, Length=270, Percent_Identity=28.1481481481481, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35989; Mature: 35858

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GTYIVRRVLIMIPVLLGITVFLFSLFQLAPGNPLASLHQDPDMTPEARERIEEQYGLNQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCC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HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]