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The map label for this gene is sigV [H]

Identifier: 188584899

GI number: 188584899

Start: 271802

End: 272362

Strand: Direct

Name: sigV [H]

Synonym: Nther_0257

Alternate gene names: 188584899

Gene position: 271802-272362 (Clockwise)

Preceding gene: 188584897

Following gene: 188584900

Centisome position: 8.59

GC content: 29.59

Gene sequence:

>561_bases
TTGATAGCAGCAAAGGGGGTTCAAACAAAATTGACAACTGAAATACAAGTTCAAAAAGCAGTTAAAGGAGATGAAGATAG
TTTTGTAAACCTGATACAGTCGAGAAAGGAAAAAATGTATCGGATAGCATTTTCATATGTGAAAAACAAAGAAGATGCTC
TAGATGTAGTCCAGGAAGTAACATATAAGGTGTACATTTCAATAGATAAACTAAAGCAGCCAGAGTACTTCGATACTTGG
CTTGTTAAAATAACTATCAACACTGCAGTAAATTATATTAAATCAAATAATAAGTACGTCTACATGGAGGCGAACAAGGA
AGTAAGAGATAGTCGATATAATAAAGATGAGATAGTTGAGATGATGGACTTAAATAATGCTTTGGATAATTTAGAGCAAA
AAAACAAAGAAATTATAATATTAAAAAGTTTTGAAGATCTCAAGTTCAAGGAAATATCAGAAATATTAGGTTATCCATTA
AATACTGTTAAAACAAACTTTTATAGAGGTTTAAAGAAAATTAAAGATAATTTGGAAGGAGGTTATAATAGTGAAGGTTA
A

Upstream 100 bases:

>100_bases
TTTGAAAAGCAAATACATTAGGAAATTAAACCAGCTTGGTAAAATATTTCTTATAAATGAAACTTTTTGTTGTATTATCT
TGTCTAATGGATGAAATAAA

Downstream 100 bases:

>100_bases
GCATAAGCTTCAGAACTTTAAAAAAGATTATCACAAAAGCATTGACATCCCTGAAGAGATTGATGATTATATAATGAAAG
GAGTTGAAAAAGGAATGCAA

Product: RNA polymerase, sigma-24 subunit, ECF subfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MIAAKGVQTKLTTEIQVQKAVKGDEDSFVNLIQSRKEKMYRIAFSYVKNKEDALDVVQEVTYKVYISIDKLKQPEYFDTW
LVKITINTAVNYIKSNNKYVYMEANKEVRDSRYNKDEIVEMMDLNNALDNLEQKNKEIIILKSFEDLKFKEISEILGYPL
NTVKTNFYRGLKKIKDNLEGGYNSEG

Sequences:

>Translated_186_residues
MIAAKGVQTKLTTEIQVQKAVKGDEDSFVNLIQSRKEKMYRIAFSYVKNKEDALDVVQEVTYKVYISIDKLKQPEYFDTW
LVKITINTAVNYIKSNNKYVYMEANKEVRDSRYNKDEIVEMMDLNNALDNLEQKNKEIIILKSFEDLKFKEISEILGYPL
NTVKTNFYRGLKKIKDNLEGGYNSEG
>Mature_186_residues
MIAAKGVQTKLTTEIQVQKAVKGDEDSFVNLIQSRKEKMYRIAFSYVKNKEDALDVVQEVTYKVYISIDKLKQPEYFDTW
LVKITINTAVNYIKSNNKYVYMEANKEVRDSRYNKDEIVEMMDLNNALDNLEQKNKEIIILKSFEDLKFKEISEILGYPL
NTVKTNFYRGLKKIKDNLEGGYNSEG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=188, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21723; Mature: 21723

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAAKGVQTKLTTEIQVQKAVKGDEDSFVNLIQSRKEKMYRIAFSYVKNKEDALDVVQEV
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
TYKVYISIDKLKQPEYFDTWLVKITINTAVNYIKSNNKYVYMEANKEVRDSRYNKDEIVE
HHEEEEEEECCCCCCCCCEEEEEEEHHHHHHHHCCCCEEEEEECCCHHHHCCCCHHHHHH
MMDLNNALDNLEQKNKEIIILKSFEDLKFKEISEILGYPLNTVKTNFYRGLKKIKDNLEG
HHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
GYNSEG
CCCCCC
>Mature Secondary Structure
MIAAKGVQTKLTTEIQVQKAVKGDEDSFVNLIQSRKEKMYRIAFSYVKNKEDALDVVQEV
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
TYKVYISIDKLKQPEYFDTWLVKITINTAVNYIKSNNKYVYMEANKEVRDSRYNKDEIVE
HHEEEEEEECCCCCCCCCEEEEEEEHHHHHHHHCCCCEEEEEECCCHHHHCCCCHHHHHH
MMDLNNALDNLEQKNKEIIILKSFEDLKFKEISEILGYPLNTVKTNFYRGLKKIKDNLEG
HHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
GYNSEG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]