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The map label for this gene is yacO [H]

Identifier: 188584816

GI number: 188584816

Start: 198084

End: 198827

Strand: Direct

Name: yacO [H]

Synonym: Nther_0174

Alternate gene names: 188584816

Gene position: 198084-198827 (Clockwise)

Preceding gene: 188584815

Following gene: 188584817

Centisome position: 6.26

GC content: 37.63

Gene sequence:

>744_bases
ATGCGGACTGACAGCCTTGTACCCGGGAAAAATCCAGTGGTTGAAGCCATAAGAGGAAATAGGAAAGTTTTTCGTATCTA
TATTTCTAAAGATTCTAACAAAAATTTTCAGGATGAGATGCTAAAATTGGCTCAACAGCATAATATTAATTTAGATAAGG
TTCCATTAGACCGATTGGATAAAATGGTGCCTACTACTGAACATCAAGGGATAGTTGCAGAAACCGAACCCTTTAAGTAC
TCCCAGTTAGACACAGTTCTTAAAGGATTTGATTATAATAATCAAAAACCACTCACCTTATTGATTTTAGACCATTTGAC
AGATCCTCAAAACTTTGGCGCTATTATCAGAACGGCTGATGCGGTGGGAGTGGATGGAGTAATTATTCCGAAACGTAGAA
GCGTAGATGTTAACCCAACCGTGATGAAAGCATCCAGTGGTGCAGCTGAACATGTTCCTATAATAAAGGTATCAAATTTA
AGACAAACTATTTCAAAATTAAAAGAGCAATGGATCTGGATTTTGGGAACTGATATAGATGGTGATAGAGGAATTTTCGA
AGAAAATTATAATATTCCCCTGGCCCTTGTGGTGGGAAACGAAGCCAGTGGTATGAGTCCATTGGTAAAGAAAGAATGTG
ATTTTATAGCCAATATTCCTATGATTGGCCGGGTGAATTCCCTTAATGCAAGTGTAGCAACAGCTGTAGTGCTTTATGAA
ATATACCGCCAAAAAACTAATTAG

Upstream 100 bases:

>100_bases
CAGTAATTTTGGATAGCAATTTTGGTAATATGGCTACTATTAAAGTGAAAACAGGCAAACATATTTATATATGTCAAGAG
TAAAAGGAGTGCTATAGGAA

Downstream 100 bases:

>100_bases
TGAAGCATGAGCCAGATCGGAGTGATATCTAAATGACAGATTATTTAATTGTAGACGGTTATAATATTATTAATGCTTGG
GACCATTTAAAAAAATCTGC

Product: RNA methyltransferase, TrmH family, group 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRTDSLVPGKNPVVEAIRGNRKVFRIYISKDSNKNFQDEMLKLAQQHNINLDKVPLDRLDKMVPTTEHQGIVAETEPFKY
SQLDTVLKGFDYNNQKPLTLLILDHLTDPQNFGAIIRTADAVGVDGVIIPKRRSVDVNPTVMKASSGAAEHVPIIKVSNL
RQTISKLKEQWIWILGTDIDGDRGIFEENYNIPLALVVGNEASGMSPLVKKECDFIANIPMIGRVNSLNASVATAVVLYE
IYRQKTN

Sequences:

>Translated_247_residues
MRTDSLVPGKNPVVEAIRGNRKVFRIYISKDSNKNFQDEMLKLAQQHNINLDKVPLDRLDKMVPTTEHQGIVAETEPFKY
SQLDTVLKGFDYNNQKPLTLLILDHLTDPQNFGAIIRTADAVGVDGVIIPKRRSVDVNPTVMKASSGAAEHVPIIKVSNL
RQTISKLKEQWIWILGTDIDGDRGIFEENYNIPLALVVGNEASGMSPLVKKECDFIANIPMIGRVNSLNASVATAVVLYE
IYRQKTN
>Mature_247_residues
MRTDSLVPGKNPVVEAIRGNRKVFRIYISKDSNKNFQDEMLKLAQQHNINLDKVPLDRLDKMVPTTEHQGIVAETEPFKY
SQLDTVLKGFDYNNQKPLTLLILDHLTDPQNFGAIIRTADAVGVDGVIIPKRRSVDVNPTVMKASSGAAEHVPIIKVSNL
RQTISKLKEQWIWILGTDIDGDRGIFEENYNIPLALVVGNEASGMSPLVKKECDFIANIPMIGRVNSLNASVATAVVLYE
IYRQKTN

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=269, Percent_Identity=27.8810408921933, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1790623, Length=191, Percent_Identity=43.979057591623, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1790083, Length=176, Percent_Identity=33.5227272727273, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788935, Length=146, Percent_Identity=26.7123287671233, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17555908, Length=260, Percent_Identity=28.0769230769231, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324775, Length=288, Percent_Identity=27.0833333333333, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27581; Mature: 27581

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTDSLVPGKNPVVEAIRGNRKVFRIYISKDSNKNFQDEMLKLAQQHNINLDKVPLDRLD
CCCCCCCCCCCHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH
KMVPTTEHQGIVAETEPFKYSQLDTVLKGFDYNNQKPLTLLILDHLTDPQNFGAIIRTAD
HHCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEECC
AVGVDGVIIPKRRSVDVNPTVMKASSGAAEHVPIIKVSNLRQTISKLKEQWIWILGTDID
CCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHHCEEEEEECCCC
GDRGIFEENYNIPLALVVGNEASGMSPLVKKECDFIANIPMIGRVNSLNASVATAVVLYE
CCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
IYRQKTN
HHHHCCC
>Mature Secondary Structure
MRTDSLVPGKNPVVEAIRGNRKVFRIYISKDSNKNFQDEMLKLAQQHNINLDKVPLDRLD
CCCCCCCCCCCHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH
KMVPTTEHQGIVAETEPFKYSQLDTVLKGFDYNNQKPLTLLILDHLTDPQNFGAIIRTAD
HHCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEECC
AVGVDGVIIPKRRSVDVNPTVMKASSGAAEHVPIIKVSNLRQTISKLKEQWIWILGTDID
CCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHHCEEEEEECCCC
GDRGIFEENYNIPLALVVGNEASGMSPLVKKECDFIANIPMIGRVNSLNASVATAVVLYE
CCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
IYRQKTN
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]