Click here to switch to the map view.

The map label for this gene is gcp [H]

Identifier: 188528375

GI number: 188528375

Start: 1603941

End: 1604963

Strand: Direct

Name: gcp [H]

Synonym: HPSH_08245

Alternate gene names: 188528375

Gene position: 1603941-1604963 (Clockwise)

Preceding gene: 188528374

Following gene: 188528376

Centisome position: 99.71

GC content: 40.86

Gene sequence:

>1023_bases
ATGATTTTAAGCATTGAAAGTTCCTGCGATGACAGCTCTTTAGCCCTTACAAGAATAAAGGACGCCAAGCTCATCGCTCA
TTTTAAAATCTCTCAAGAAAAGCACCACAGCTCTTATGGGGGCGTTGTGCCTGAGCTTGCATCGCGCTTGCATGCTGAGA
ATTTGCCGCTCTTATTAGAACGCATCAAAATCAGCTTGAATAAGGATTTTTCTAAAATTAAAGCCATCGCTATCACTAAT
CAGCCAGGTTTGAGCGTTACCTTAATAGAAGGTTTGATGATGGCAAAAGCCTTGAGCTTGTCTTTGAATTTACCCTTGAT
TTTAGAAGACCATTTGAGAGGGCATGTGTATTCGCTCTTTATCAATGAAAAACAAACCTGCATGCCTTTAAGCGCACTCT
TAGTCTCTGGGGGGCATTCTTTGATTTTAGAGGCCAGAGATTATGAAGACATTAAAATCGTTGCCACGAGTTTAGACGAT
AGCTTTGGAGAGAGTTTTGATAAGGTTTCCAAAATGCTTGATTTAGGCTATCCAGGAGGCCCCATAGTGGAAAAATTAGC
CCTTGATTATGCGCATCAAAACGAGCCTTTAATGTTTCCTATCCCTTTAAAAAACAGCCAGAATCTGGCTTTTAGTTTTT
CAGGTTTAAAAAATGCGGTGCGTTTGGAGGTTGAAAAAAACGCCCCCAATTTGAATGAAGCGATCAAACAAAAGATTAGC
TATCATTTTCAAAGTGCGGCCATTGAGCATCTAATCCAGCAGACTAAACGCTATTTTAAAATCAAACGCCCTAAAATTTT
TGGCATTGTGGGGGGAGCGAGCCAGAATCTGGCTTTAAGAAAGGCGTTTGAAAATTTGTGCGATGAGTTTGATTGCAAGC
TTGTTTTAGCCCCTTTAGAATTTTGCAACGACAATGCCGCCATGATAGGGCGATCCAGCCTAGAAGCTTACCAACAAAAA
CGCTTTGTCCCTTTAGAAAAGGCCAACATTTCGCCAAGAACGCTGTTAAAAAGTTTTGAGTGA

Upstream 100 bases:

>100_bases
CAAAAGCTATGTGAATGCGATCAAATATTTGGCTTAAAGATTTTAAAATACAAGCCAACAAAGTATAATTCAAGCAAAAA
CACCACCCAAAGATAAAGGC

Downstream 100 bases:

>100_bases
ATGGGTGTGAAAAGAAAGCGCATAATAAAACGCCCTAAAATTTAAGCGTCAAATATCGGTTATTTTGAGGCAAGAGCTTA
AAAAAGAGAGCGTTAAAACA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MILSIESSCDDSSLALTRIKDAKLIAHFKISQEKHHSSYGGVVPELASRLHAENLPLLLERIKISLNKDFSKIKAIAITN
QPGLSVTLIEGLMMAKALSLSLNLPLILEDHLRGHVYSLFINEKQTCMPLSALLVSGGHSLILEARDYEDIKIVATSLDD
SFGESFDKVSKMLDLGYPGGPIVEKLALDYAHQNEPLMFPIPLKNSQNLAFSFSGLKNAVRLEVEKNAPNLNEAIKQKIS
YHFQSAAIEHLIQQTKRYFKIKRPKIFGIVGGASQNLALRKAFENLCDEFDCKLVLAPLEFCNDNAAMIGRSSLEAYQQK
RFVPLEKANISPRTLLKSFE

Sequences:

>Translated_340_residues
MILSIESSCDDSSLALTRIKDAKLIAHFKISQEKHHSSYGGVVPELASRLHAENLPLLLERIKISLNKDFSKIKAIAITN
QPGLSVTLIEGLMMAKALSLSLNLPLILEDHLRGHVYSLFINEKQTCMPLSALLVSGGHSLILEARDYEDIKIVATSLDD
SFGESFDKVSKMLDLGYPGGPIVEKLALDYAHQNEPLMFPIPLKNSQNLAFSFSGLKNAVRLEVEKNAPNLNEAIKQKIS
YHFQSAAIEHLIQQTKRYFKIKRPKIFGIVGGASQNLALRKAFENLCDEFDCKLVLAPLEFCNDNAAMIGRSSLEAYQQK
RFVPLEKANISPRTLLKSFE
>Mature_340_residues
MILSIESSCDDSSLALTRIKDAKLIAHFKISQEKHHSSYGGVVPELASRLHAENLPLLLERIKISLNKDFSKIKAIAITN
QPGLSVTLIEGLMMAKALSLSLNLPLILEDHLRGHVYSLFINEKQTCMPLSALLVSGGHSLILEARDYEDIKIVATSLDD
SFGESFDKVSKMLDLGYPGGPIVEKLALDYAHQNEPLMFPIPLKNSQNLAFSFSGLKNAVRLEVEKNAPNLNEAIKQKIS
YHFQSAAIEHLIQQTKRYFKIKRPKIFGIVGGASQNLALRKAFENLCDEFDCKLVLAPLEFCNDNAAMIGRSSLEAYQQK
RFVPLEKANISPRTLLKSFE

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=338, Percent_Identity=27.2189349112426, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI8923380, Length=334, Percent_Identity=21.5568862275449, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1789445, Length=339, Percent_Identity=33.3333333333333, Blast_Score=178, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17557464, Length=331, Percent_Identity=31.1178247734139, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI71995670, Length=323, Percent_Identity=26.0061919504644, Blast_Score=81, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320099, Length=354, Percent_Identity=29.3785310734463, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI20129063, Length=346, Percent_Identity=28.0346820809249, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21357207, Length=345, Percent_Identity=24.0579710144928, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37863; Mature: 37863

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSIESSCDDSSLALTRIKDAKLIAHFKISQEKHHSSYGGVVPELASRLHAENLPLLLE
CEEEECCCCCCCCEEEEEECCCEEEEEEEECHHHCCCCCCCHHHHHHHHHCCCCCHHHHH
RIKISLNKDFSKIKAIAITNQPGLSVTLIEGLMMAKALSLSLNLPLILEDHLRGHVYSLF
HHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEE
INEKQTCMPLSALLVSGGHSLILEARDYEDIKIVATSLDDSFGESFDKVSKMLDLGYPGG
ECCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCC
PIVEKLALDYAHQNEPLMFPIPLKNSQNLAFSFSGLKNAVRLEVEKNAPNLNEAIKQKIS
HHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
YHFQSAAIEHLIQQTKRYFKIKRPKIFGIVGGASQNLALRKAFENLCDEFDCKLVLAPLE
HHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEHH
FCNDNAAMIGRSSLEAYQQKRFVPLEKANISPRTLLKSFE
HCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHCCC
>Mature Secondary Structure
MILSIESSCDDSSLALTRIKDAKLIAHFKISQEKHHSSYGGVVPELASRLHAENLPLLLE
CEEEECCCCCCCCEEEEEECCCEEEEEEEECHHHCCCCCCCHHHHHHHHHCCCCCHHHHH
RIKISLNKDFSKIKAIAITNQPGLSVTLIEGLMMAKALSLSLNLPLILEDHLRGHVYSLF
HHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEE
INEKQTCMPLSALLVSGGHSLILEARDYEDIKIVATSLDDSFGESFDKVSKMLDLGYPGG
ECCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCC
PIVEKLALDYAHQNEPLMFPIPLKNSQNLAFSFSGLKNAVRLEVEKNAPNLNEAIKQKIS
HHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
YHFQSAAIEHLIQQTKRYFKIKRPKIFGIVGGASQNLALRKAFENLCDEFDCKLVLAPLE
HHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEHH
FCNDNAAMIGRSSLEAYQQKRFVPLEKANISPRTLLKSFE
HCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA