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The map label for this gene is yabD [H]

Identifier: 188528365

GI number: 188528365

Start: 1596409

End: 1597173

Strand: Reverse

Name: yabD [H]

Synonym: HPSH_08195

Alternate gene names: 188528365

Gene position: 1597173-1596409 (Counterclockwise)

Preceding gene: 188528370

Following gene: 188528364

Centisome position: 99.29

GC content: 39.48

Gene sequence:

>765_bases
ATGTTTATTGACACGCATTGCCATTTGGATCACAGGGATTATGAAAACGATTTAGAAGAAGTGTTAAAAGAAAGCCTAGA
AAAAGGCGTGACTCAATGCGTGATTCCGGGTGCAGACATGAAGGATTTGAAGAGAGCGATAGAGATTAGCGAAAAATTTG
AAGGCGTGTTTTTTGCCATAGGCGCTCACCCTTATGATGTGGAAAGCTTTGATGAAAGCCTGTTTGAAAAGTTTGTTGGG
CATCAAAAATGCGTGGCGATAGGCGAATGCGGGCTGGATTACTACCGCTTGCCTGAATTGGATGAAAGAGAAAATTATAA
AAACAAGCAAAAAGAAATTTTTACCAAACAGATTGAATTTTCTATCCAACACAACAAGCCCTTGATTATCCACATCAGAG
AGGCGAGTTTTGATAGTTTGAATATTTTAAAAAGCTATCCTAAGGCTTTTGGGGTGCTGCATTGCTTTAACGCTGATAAC
ATGCTTTTAGAATTAAGCGATCGTTTTTATTATGGGATAGGAGGGGTTAGCACTTTTAAAAACGCTAAAAGACTGGTAGA
GATCCTCCCTAAAATCCCTAAAAACAGGCTTCTTTTAGAAACGGATTCGCCCTATTTGACCCCACACCCTTTTAGAGGCA
CCAGAAATAGCCCTATATATATCCCTTTAATCGCTCAAAAAATTGCCGAAATCATCAACATAGAAACTGAAGAGCTCGCT
TCTTTAAGCACGCATAACGCCCAAACGCTCTTTAATTTCCCCTAA

Upstream 100 bases:

>100_bases
ATTTGATGGATTAGGCCGCTGAACATCGTTAATGATTATTTTCCTTATGTTAAAATGCTTAAGTATTGTAACATATTAAA
TAAAACCACAGGATAAAAGC

Downstream 100 bases:

>100_bases
AAATGGGGCTGTGTTAGAAAGCGTTATTCAAGTTTAGTTATAATCAAAGCTATTTTAAAAGCTGAATAGCTGTAGTTATT
AGGATGTGATGCCAAAAAGA

Product: DNAse

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MFIDTHCHLDHRDYENDLEEVLKESLEKGVTQCVIPGADMKDLKRAIEISEKFEGVFFAIGAHPYDVESFDESLFEKFVG
HQKCVAIGECGLDYYRLPELDERENYKNKQKEIFTKQIEFSIQHNKPLIIHIREASFDSLNILKSYPKAFGVLHCFNADN
MLLELSDRFYYGIGGVSTFKNAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPIYIPLIAQKIAEIINIETEELA
SLSTHNAQTLFNFP

Sequences:

>Translated_254_residues
MFIDTHCHLDHRDYENDLEEVLKESLEKGVTQCVIPGADMKDLKRAIEISEKFEGVFFAIGAHPYDVESFDESLFEKFVG
HQKCVAIGECGLDYYRLPELDERENYKNKQKEIFTKQIEFSIQHNKPLIIHIREASFDSLNILKSYPKAFGVLHCFNADN
MLLELSDRFYYGIGGVSTFKNAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPIYIPLIAQKIAEIINIETEELA
SLSTHNAQTLFNFP
>Mature_254_residues
MFIDTHCHLDHRDYENDLEEVLKESLEKGVTQCVIPGADMKDLKRAIEISEKFEGVFFAIGAHPYDVESFDESLFEKFVG
HQKCVAIGECGLDYYRLPELDERENYKNKQKEIFTKQIEFSIQHNKPLIIHIREASFDSLNILKSYPKAFGVLHCFNADN
MLLELSDRFYYGIGGVSTFKNAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPIYIPLIAQKIAEIINIETEELA
SLSTHNAQTLFNFP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=26.5151515151515, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=27.0676691729323, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=27.007299270073, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI226061614, Length=251, Percent_Identity=25.8964143426295, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI14042943, Length=281, Percent_Identity=29.1814946619217, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI225903424, Length=230, Percent_Identity=31.304347826087, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI225903439, Length=261, Percent_Identity=29.1187739463602, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=25.5411255411255, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1787342, Length=273, Percent_Identity=36.996336996337, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI48994985, Length=270, Percent_Identity=29.6296296296296, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082439, Length=266, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=290, Percent_Identity=27.9310344827586, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71980746, Length=266, Percent_Identity=29.3233082706767, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17543026, Length=193, Percent_Identity=29.0155440414508, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565396, Length=305, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648690, Length=290, Percent_Identity=30.6896551724138, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24586117, Length=291, Percent_Identity=27.4914089347079, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI221330018, Length=291, Percent_Identity=27.4914089347079, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29287; Mature: 29287

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDTHCHLDHRDYENDLEEVLKESLEKGVTQCVIPGADMKDLKRAIEISEKFEGVFFAI
CEECCEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCEEEEEE
GAHPYDVESFDESLFEKFVGHQKCVAIGECGLDYYRLPELDERENYKNKQKEIFTKQIEF
CCCCCCHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEE
SIQHNKPLIIHIREASFDSLNILKSYPKAFGVLHCFNADNMLLELSDRFYYGIGGVSTFK
EEECCCCEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCEEEEECCCEEECCCCHHHHH
NAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPIYIPLIAQKIAEIINIETEELA
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCHHHHH
SLSTHNAQTLFNFP
HHHCCCCCEEECCC
>Mature Secondary Structure
MFIDTHCHLDHRDYENDLEEVLKESLEKGVTQCVIPGADMKDLKRAIEISEKFEGVFFAI
CEECCEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCEEEEEE
GAHPYDVESFDESLFEKFVGHQKCVAIGECGLDYYRLPELDERENYKNKQKEIFTKQIEF
CCCCCCHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEE
SIQHNKPLIIHIREASFDSLNILKSYPKAFGVLHCFNADNMLLELSDRFYYGIGGVSTFK
EEECCCCEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCEEEEECCCEEECCCCHHHHH
NAKRLVEILPKIPKNRLLLETDSPYLTPHPFRGTRNSPIYIPLIAQKIAEIINIETEELA
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCHHHHH
SLSTHNAQTLFNFP
HHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]