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The map label for this gene is kdsC [H]

Identifier: 188528362

GI number: 188528362

Start: 1593758

End: 1594252

Strand: Reverse

Name: kdsC [H]

Synonym: HPSH_08180

Alternate gene names: 188528362

Gene position: 1594252-1593758 (Counterclockwise)

Preceding gene: 188528363

Following gene: 188528361

Centisome position: 99.11

GC content: 41.01

Gene sequence:

>495_bases
ATGATTAAGTTATTGCTTTTAGATGTGGATGGCACGCTCACAGACGGATCGTTGTATTTTGATGAAAATTTTCACGAGAT
GAAGGCTTTTAATGTCAAAGACGGGCTTGGCATGACGCTATGGCAAAAATTAGGCAAAAAAATCGCTATCATTACAGGAA
GAACTTCAATAATGGTCAAAAAACGCATGGAGAGTTTGGGCGTTCAGTTTATTTTTATGGGCGTTGAAAATAAAGGCGTG
GTTGTGGAACGGCTCAAAAAAGACTTGCAATTAAGTGTGCAAGAAATCGCATGCGTAGGCGATGATTATAACGATTTAGG
CATGTTTAAGGCGTGCGCTTTGAGTTTCGCTCCTTTTGATGCGCACCCCTTGCTTAAAAGCAAGGCCTATAAAGTGTTAC
AAAATTCAGGGGGCAAGGGGGCTGTTAGGGAAGCGATTGATTATCTTTTAACATTAGAAGGCTTGCAAGATGAAGCGCTC
AAGCTTTACCTCTAA

Upstream 100 bases:

>100_bases
AAGACGATTTGTATAAAGTTTTAGTTCAAGGGTTTCAAAGCGAAGAAGAGGCTAGGGATTTTATGAAAAAATATAACCAG
AATGCGGTTTTAACCAGAGA

Downstream 100 bases:

>100_bases
TAGCGTTTTAAACTTTTTTGTGGTTTTGTCTTTCGTCACGATAGGGTTAGTTTTTTTCTTTTTGCGCTCCCAACCCACTA
GCGTGGTTTCTAAAGAAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MIKLLLLDVDGTLTDGSLYFDENFHEMKAFNVKDGLGMTLWQKLGKKIAIITGRTSIMVKKRMESLGVQFIFMGVENKGV
VVERLKKDLQLSVQEIACVGDDYNDLGMFKACALSFAPFDAHPLLKSKAYKVLQNSGGKGAVREAIDYLLTLEGLQDEAL
KLYL

Sequences:

>Translated_164_residues
MIKLLLLDVDGTLTDGSLYFDENFHEMKAFNVKDGLGMTLWQKLGKKIAIITGRTSIMVKKRMESLGVQFIFMGVENKGV
VVERLKKDLQLSVQEIACVGDDYNDLGMFKACALSFAPFDAHPLLKSKAYKVLQNSGGKGAVREAIDYLLTLEGLQDEAL
KLYL
>Mature_164_residues
MIKLLLLDVDGTLTDGSLYFDENFHEMKAFNVKDGLGMTLWQKLGKKIAIITGRTSIMVKKRMESLGVQFIFMGVENKGV
VVERLKKDLQLSVQEIACVGDDYNDLGMFKACALSFAPFDAHPLLKSKAYKVLQNSGGKGAVREAIDYLLTLEGLQDEAL
KLYL

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=152, Percent_Identity=30.9210526315789, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI2367202, Length=158, Percent_Identity=43.0379746835443, Blast_Score=124, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18255; Mature: 18255

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLLLLDVDGTLTDGSLYFDENFHEMKAFNVKDGLGMTLWQKLGKKIAIITGRTSIMVK
CEEEEEEECCCCEECCEEEECCCCHHHEEECCCCCCCHHHHHHCCCEEEEEECCHHHHHH
KRMESLGVQFIFMGVENKGVVVERLKKDLQLSVQEIACVGDDYNDLGMFKACALSFAPFD
HHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
AHPLLKSKAYKVLQNSGGKGAVREAIDYLLTLEGLQDEALKLYL
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEECC
>Mature Secondary Structure
MIKLLLLDVDGTLTDGSLYFDENFHEMKAFNVKDGLGMTLWQKLGKKIAIITGRTSIMVK
CEEEEEEECCCCEECCEEEECCCCHHHEEECCCCCCCHHHHHHCCCEEEEEECCHHHHHH
KRMESLGVQFIFMGVENKGVVVERLKKDLQLSVQEIACVGDDYNDLGMFKACALSFAPFD
HHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
AHPLLKSKAYKVLQNSGGKGAVREAIDYLLTLEGLQDEALKLYL
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]