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The map label for this gene is tsf

Identifier: 188528329

GI number: 188528329

Start: 1558389

End: 1559456

Strand: Reverse

Name: tsf

Synonym: HPSH_08005

Alternate gene names: 188528329

Gene position: 1559456-1558389 (Counterclockwise)

Preceding gene: 188528330

Following gene: 188528328

Centisome position: 96.95

GC content: 40.17

Gene sequence:

>1068_bases
ATGTCAGGAATTAGCGCTCAATTAGTCAAAAAATTAAGGGACTTAACCGATGCGGGCATGATGGATTGCAAAAAAGCCCT
TGTAGAAGTGGCTGGGGATTTGCAAAAGGCTATTGATTTCTTGCGCGAAAAAGGCTTGAGTAAAGCCGCTAAAAAAGCCG
ATAGGATCGCTGCTGAGGGCGTAATCGCTTTAGAAGTAGTGCCTGATTTTAAAAGCGCGATGATGGTAGAAATCAATAGC
GAAACGGATTTTGTGGCTAAAAATGAGGGCTTTAAGGAATTGGTGAAAAAAACTTTAGAAACGATCAAAGCCCACAATAT
TCACACCACAGAAGAACTGCTTAAAAGCCCGTTAGACAACAAGCCTTTTGAAGAATATTTGCACTCTCAAATCGCTGTGA
TTGGTGAAAACATTTTAGTGAGAAAAATCGCTCATTTAAAAGCCCCTAGCTTTCACATCATCAATGGCTATGCGCATTCT
AACGCTAGAGTGGGCGTGTTAATCACCATAAAATACGATAATGAGAAAAACGCTCCAAAAGTGGTGGAATTGGCCCGAAA
CATCGCTATGCATGCCGCAGCGATGAAACCTCAAGTATTAGACAGCAAAGACTTTAGCCTTGATTTTGTCAAAAAAGAAA
CTTTAGCCTTGATCGCTGAAATTGAAAAAGACAATGAAGAGGCTAAACGCTTGGGCAAACCTTTAAAAAATATTCCTACT
TTTGGGAGCCGCATTGAATTGAGCGATGAAGTTTTAGCGCACCAAAAAAAAGCCTTTGAAGACGAATTAAAAGCGCAAGG
CAAGCCTGAAAAAATCTGGGATAAAATCGTTCCTGGAAAAATGGAAAGATTTATCGCTGATAACACCCTTATTGATCAAC
GCCTAACCCTTTTAGGGCAATTCTATGTCATGGACGATAAAAAAACTATCGCTCAAGTGGTTGCTGATTGTTCCAAAGAG
TGGGATGACCATTTAACAATCACTGAGTATGTGCGTTTTGAATTGGGCGAAGGCATTGAGAAAAAGGCAGAAAATTTCGC
TGAAGAAGTGGCTTTGCAAATGAAATAG

Upstream 100 bases:

>100_bases
ATGCGGATGAAAACAGCGAAGAGATAGAGTATGTGAGCAATGAAGAAAAAGAAGAAATGCTCGCTGAAATCCAAAAAGAA
ATCACTCAAGGAGCCGAATA

Downstream 100 bases:

>100_bases
GGTTTTAAAGCGCGTTTTTGCGCTTTAAAAACTAACTTTCAATAAACTAACATGCCTTACAGATTAGAAAAAGACTTCCA
AGACTTAATCGCTAGCAATA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEGVIALEVVPDFKSAMMVEINS
ETDFVAKNEGFKELVKKTLETIKAHNIHTTEELLKSPLDNKPFEEYLHSQIAVIGENILVRKIAHLKAPSFHIINGYAHS
NARVGVLITIKYDNEKNAPKVVELARNIAMHAAAMKPQVLDSKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPT
FGSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVVADCSKE
WDDHLTITEYVRFELGEGIEKKAENFAEEVALQMK

Sequences:

>Translated_355_residues
MSGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEGVIALEVVPDFKSAMMVEINS
ETDFVAKNEGFKELVKKTLETIKAHNIHTTEELLKSPLDNKPFEEYLHSQIAVIGENILVRKIAHLKAPSFHIINGYAHS
NARVGVLITIKYDNEKNAPKVVELARNIAMHAAAMKPQVLDSKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPT
FGSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVVADCSKE
WDDHLTITEYVRFELGEGIEKKAENFAEEVALQMK
>Mature_354_residues
SGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEGVIALEVVPDFKSAMMVEINSE
TDFVAKNEGFKELVKKTLETIKAHNIHTTEELLKSPLDNKPFEEYLHSQIAVIGENILVRKIAHLKAPSFHIINGYAHSN
ARVGVLITIKYDNEKNAPKVVELARNIAMHAAAMKPQVLDSKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPTF
GSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVVADCSKEW
DDHLTITEYVRFELGEGIEKKAENFAEEVALQMK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=234, Percent_Identity=29.0598290598291, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786366, Length=355, Percent_Identity=36.3380281690141, Blast_Score=182, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17561440, Length=221, Percent_Identity=28.0542986425339, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 39840; Mature: 39708

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
VIALEVVPDFKSAMMVEINSETDFVAKNEGFKELVKKTLETIKAHNIHTTEELLKSPLDN
EEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC
KPFEEYLHSQIAVIGENILVRKIAHLKAPSFHIINGYAHSNARVGVLITIKYDNEKNAPK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECEECCCCEEEEEEEEEECCCCCCHH
VVELARNIAMHAAAMKPQVLDSKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPT
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHCCC
FGSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQ
CCCEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
FYVMDDKKTIAQVVADCSKEWDDHLTITEYVRFELGEGIEKKAENFAEEVALQMK
HHEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
VIALEVVPDFKSAMMVEINSETDFVAKNEGFKELVKKTLETIKAHNIHTTEELLKSPLDN
EEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC
KPFEEYLHSQIAVIGENILVRKIAHLKAPSFHIINGYAHSNARVGVLITIKYDNEKNAPK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECEECCCCEEEEEEEEEECCCCCCHH
VVELARNIAMHAAAMKPQVLDSKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPT
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHCCC
FGSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQ
CCCEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
FYVMDDKKTIAQVVADCSKEWDDHLTITEYVRFELGEGIEKKAENFAEEVALQMK
HHEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA