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The map label for this gene is 188528275

Identifier: 188528275

GI number: 188528275

Start: 1497362

End: 1498396

Strand: Reverse

Name: 188528275

Synonym: HPSH_07725

Alternate gene names: NA

Gene position: 1498396-1497362 (Counterclockwise)

Preceding gene: 188528276

Following gene: 188528274

Centisome position: 93.15

GC content: 40.58

Gene sequence:

>1035_bases
ATGAGACTTTATGAGAGTTTATTAGAAATTTGCTTGAATAAGGCGTGGGAGCATCAAACCCTAGCCCTAGAAAACCCAAG
CGTGGCTTGCATGGTGCTAGATAAAAACCATGAGATCTTGAGTTTAGAAACCCACAAAAAGGCCAAAACCCCGCATGCAG
AAGTCTTAGCCGCCCAATCAGCGTTAAAGATTTTACGCCCCGGTTTGAAAAACGATTTAGAAAAATTAGAAGACCCTAAA
ACTTTAAGCGATTTTTTAAAAACACACCACAACAACGCTTTTAAAGACTGCGTTTTTTTAATCACCCTAGAACCATGCAA
TTCTTATGGCAAAACCCCGGCGTGCAGCGGGTTGTTAGAAATTTTAAAGCCTAAAAGAGTGGTCATTGCCACAGAAGAAA
ACGAAGCGAAAAAAGGGGGTTTAGCAAGGCTAAAAAAGGCTCGTATTGAAGGGGTGGTTTGTGAGAGTTTAAAAAACAAG
GCTAAAGACTTGCTCCTGCCTTTTAGGATAATGGAACAAAAGGGGCGTTTTAATTTGTTCAAACTCGCTTTAAGGATGAA
TGGGGATTATTGTCATGGCAAAATCACCGGGCAAAAAAGCGTTGTTTTCACGCACAACCAGCGAGCAATATGCGACACGC
TTATTGTTTCTGGGAAAACCATAAGAACGGATAACCCCTTATTAGACACTCGCTTTTGCGATAGCTTTTATCAAAATAAA
AACCCCAATATCGCTATTTTATCCAAGCATTCAATTGACCCCAATTCAAAGGTTTTTTCTGCACCTAATCGTTTGGTTAA
TGCTTTCTATGACCCTAAAGATTTGCCCCTAGAGAAGGGGTTTAATTTCATTGAAGGGGGGTGGGAATTGTTTGAGAGCT
TGAGGGATAAAATAGACGCATTGCTTTTGCATTCGCATGCGTCTATGATTAGCGAAGCGTTTAGCGCACTCGCTCTAAAA
ACCCCTTTTAAAGGGCGGTTGTTGCATGCGCAAATCTTAGAAAATGAAGCCCTTTTATGGATAGAAAACTCTTAA

Upstream 100 bases:

>100_bases
ATGTAGCGTTTATCGTCGTGCCTTTGGTGGGAGCGTTTTTTGTTGATATTATTAACGCTTTAGCGATTAAAGGCTTTTTG
CTCTTGCCTTTTTTCCCGTC

Downstream 100 bases:

>100_bases
GATTATACCAGCCTTTAAACGCTTATTCTTACAATAGCGATTCGCTTTTTTTATACGATTTTTCACGCCCTTTTATCAAA
AATAGCGGCGCGATTTTAGA

Product: riboflavin biosynthesis protein (ribG)

Products: 5-amino-6-(5-phosphoribosylamino)uracil; NH3

Alternate protein names: Riboflavin Biosynthesis Protein; Riboflavin Biosynthesis Protein RibG; Bifunctional Riboflavin Biosynthesis Protein RibD; Riboflavin Biosynthesis Protein Ribd; Riboflavin-Specific Deaminase; Priboflavin-Specific Deaminase

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MRLYESLLEICLNKAWEHQTLALENPSVACMVLDKNHEILSLETHKKAKTPHAEVLAAQSALKILRPGLKNDLEKLEDPK
TLSDFLKTHHNNAFKDCVFLITLEPCNSYGKTPACSGLLEILKPKRVVIATEENEAKKGGLARLKKARIEGVVCESLKNK
AKDLLLPFRIMEQKGRFNLFKLALRMNGDYCHGKITGQKSVVFTHNQRAICDTLIVSGKTIRTDNPLLDTRFCDSFYQNK
NPNIAILSKHSIDPNSKVFSAPNRLVNAFYDPKDLPLEKGFNFIEGGWELFESLRDKIDALLLHSHASMISEAFSALALK
TPFKGRLLHAQILENEALLWIENS

Sequences:

>Translated_344_residues
MRLYESLLEICLNKAWEHQTLALENPSVACMVLDKNHEILSLETHKKAKTPHAEVLAAQSALKILRPGLKNDLEKLEDPK
TLSDFLKTHHNNAFKDCVFLITLEPCNSYGKTPACSGLLEILKPKRVVIATEENEAKKGGLARLKKARIEGVVCESLKNK
AKDLLLPFRIMEQKGRFNLFKLALRMNGDYCHGKITGQKSVVFTHNQRAICDTLIVSGKTIRTDNPLLDTRFCDSFYQNK
NPNIAILSKHSIDPNSKVFSAPNRLVNAFYDPKDLPLEKGFNFIEGGWELFESLRDKIDALLLHSHASMISEAFSALALK
TPFKGRLLHAQILENEALLWIENS
>Mature_344_residues
MRLYESLLEICLNKAWEHQTLALENPSVACMVLDKNHEILSLETHKKAKTPHAEVLAAQSALKILRPGLKNDLEKLEDPK
TLSDFLKTHHNNAFKDCVFLITLEPCNSYGKTPACSGLLEILKPKRVVIATEENEAKKGGLARLKKARIEGVVCESLKNK
AKDLLLPFRIMEQKGRFNLFKLALRMNGDYCHGKITGQKSVVFTHNQRAICDTLIVSGKTIRTDNPLLDTRFCDSFYQNK
NPNIAILSKHSIDPNSKVFSAPNRLVNAFYDPKDLPLEKGFNFIEGGWELFESLRDKIDALLLHSHASMISEAFSALALK
TPFKGRLLHAQILENEALLWIENS

Specific function: Unknown

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.5.4.26; 1.1.1.193

Molecular weight: Translated: 38785; Mature: 38785

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLYESLLEICLNKAWEHQTLALENPSVACMVLDKNHEILSLETHKKAKTPHAEVLAAQS
CCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHH
ALKILRPGLKNDLEKLEDPKTLSDFLKTHHNNAFKDCVFLITLEPCNSYGKTPACSGLLE
HHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHH
ILKPKRVVIATEENEAKKGGLARLKKARIEGVVCESLKNKAKDLLLPFRIMEQKGRFNLF
HCCCCEEEEEECCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
KLALRMNGDYCHGKITGQKSVVFTHNQRAICDTLIVSGKTIRTDNPLLDTRFCDSFYQNK
EEEEEECCCEEEEEECCCCEEEEECCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCC
NPNIAILSKHSIDPNSKVFSAPNRLVNAFYDPKDLPLEKGFNFIEGGWELFESLRDKIDA
CCCEEEEEECCCCCCCCEECCCHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
LLLHSHASMISEAFSALALKTPFKGRLLHAQILENEALLWIENS
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEECCCCEEEEEECC
>Mature Secondary Structure
MRLYESLLEICLNKAWEHQTLALENPSVACMVLDKNHEILSLETHKKAKTPHAEVLAAQS
CCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHH
ALKILRPGLKNDLEKLEDPKTLSDFLKTHHNNAFKDCVFLITLEPCNSYGKTPACSGLLE
HHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHH
ILKPKRVVIATEENEAKKGGLARLKKARIEGVVCESLKNKAKDLLLPFRIMEQKGRFNLF
HCCCCEEEEEECCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
KLALRMNGDYCHGKITGQKSVVFTHNQRAICDTLIVSGKTIRTDNPLLDTRFCDSFYQNK
EEEEEECCCEEEEEECCCCEEEEECCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCC
NPNIAILSKHSIDPNSKVFSAPNRLVNAFYDPKDLPLEKGFNFIEGGWELFESLRDKIDA
CCCEEEEEECCCCCCCCEECCCHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
LLLHSHASMISEAFSALALKTPFKGRLLHAQILENEALLWIENS
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2,5-Diamino-6-hydroxy-4-(5'-phosphoribosylamino)-pyrimidine; H2O

Specific reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O = 5-amino-6-(5-phosphoribosylamino)uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA