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The map label for this gene is oxaA [H]

Identifier: 188528220

GI number: 188528220

Start: 1437754

End: 1439394

Strand: Direct

Name: oxaA [H]

Synonym: HPSH_07420

Alternate gene names: 188528220

Gene position: 1437754-1439394 (Clockwise)

Preceding gene: 188528219

Following gene: 188528221

Centisome position: 89.38

GC content: 40.59

Gene sequence:

>1641_bases
ATGGATAAAAACAACAACGCCAATATTCGCTTGATTTTAGCGATCGCTCTGTCTTTCTTGTTTATCGCTATTTACAGCTA
TTTTTTCCAAAAACCAAACAAAACAACAACCCCAACCACAAAGCAAGAAACAACCAACAACCACACAACAACAAACCCTA
ACACGCCCAACGCTTTTAACGCCACTCAAGCAATCCCCCAAGAGAATTTGTTAAGCACGATTTCTTTTGAGCATGCCAGA
ATTGAAATTGATTCTTTAGGGCGTATCAAACAGGTTTATCTCAAGGATAAAAAGTATCTAACCCCCAAACAAAAGGGCTT
TTTAGAGCATGTGAGCCATCTTTTTAACCCCAAAGCTAACCCGCAAACCCCCCTAAAAGAGCTCCCCCTTTTAGCAGCCG
ATAAACTCAAGCCTTTAGAAGTGCGTTTTTTAGACCCCACGCTCAATAACAAAGCGTTCAACACCCCTTATAGCGCTTCA
AAAACCACTCTTGGGCCTAATGAGCAGCTTGTTTTAACCCAAGATTTAGGCGCTCTTACCATCATTAAAACCCTGACTTT
TTATGATGATTTGCATTATGATTTGCAAATCGCCTTCAAATCGCCCAACAAGATTATCCCTAGCTATGTGATCACTAATG
GTTACAAGCCGGTGGCCGATTTGGACAGCTACACCTTTTCAGGCGTGCTTTTAGAAAACAACGACAAAAAAATTGAAAAA
ATTGAAGATAAAGACGCTAAAGAGATCAAGCGCTTTTCTAACACCCTCTTTTTATCTAGCGTGGATAGGTATTTCACCAC
CTTGCTTTTCACTAAAGATCCTCAAGGTTTTGAAGCCTTAATTGATTCAGAAATCGGCACTAAAAACCCCTTAGGGTTCA
TTTCCCTTAAAAATGAAGCGAATTTGCATGGTTATATTGGCCCTAAAGATTACCGCTCTTTGAAAGCGATTTCACCCATG
CTCACTGATGTGATAGAGTATGGCTTGATCACTTTCTTTGCTAAAGGCGTGTTTGTTTTACTGGATTATTTGTATCAATT
TGTGGGTAATTGGGGTTGGGCTATCATTCTTTTAACGATTATCGTGCGCCTAATCCTCTACCCCTTAAGCTATAAAGGCA
TGGTGAGCATGCAAAAGCTCAAAGAAATAGCCCCTAAAATGAAGGAACTCCAAGAAAAATACAAGGACGAACCCCAAAAG
TTGCAAGCCCACATGATGCAACTTTACAAAAAACATGGGGCTAACCCGCTAGGGGGTTGTCTGCCCTTAATCTTGCAAAT
CCCGGTGTTTTTTGCGATCTATAGAGTGCTTTATAATGCGGTGGAATTGAAAAGCTCAGAGTGGATCTTATGGATTCATG
ATCTATCCATCATGGATCCGTATTTTATTTTACCGCTTCTTATGGGAGCGTCTATGTATTGGCACCAAAGCGTTACGCCA
AGCAGCGTGACCGATCCCATGCAAGCGAAGCTCTTTAAATTCTTACCCCTATTATTCACAATCTTTTTAATCACTTTCCC
TGCAGGGTTAGTCTTGTATTGGACCACGAACAACATCCTTTCGGTGTTGCAACAACTCATTATCAATAAAGTCTTAGAGA
ATAAAAAACGCATGCACGCGCAAAACAAAAAGGAAAGTTGA

Upstream 100 bases:

>100_bases
CTCATAAAGATTTTAATCGCAATTTTAAAACCATTACTTTTTGGCTCGTTCCTACTACAAAAAGCCACGCAACTTACTAC
ATCATTAAGGTTTAATCACA

Downstream 100 bases:

>100_bases
TGCAAAATCCTATTGAAATCAAAGCCAAAACCTTAGAAGAAGCCCTCATTCAAGCTTCTATCGCCTTGAATTGCCCCATT
ATCAATTTGCAATACGAAGT

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MDKNNNANIRLILAIALSFLFIAIYSYFFQKPNKTTTPTTKQETTNNHTTTNPNTPNAFNATQAIPQENLLSTISFEHAR
IEIDSLGRIKQVYLKDKKYLTPKQKGFLEHVSHLFNPKANPQTPLKELPLLAADKLKPLEVRFLDPTLNNKAFNTPYSAS
KTTLGPNEQLVLTQDLGALTIIKTLTFYDDLHYDLQIAFKSPNKIIPSYVITNGYKPVADLDSYTFSGVLLENNDKKIEK
IEDKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEALIDSEIGTKNPLGFISLKNEANLHGYIGPKDYRSLKAISPM
LTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIILLTIIVRLILYPLSYKGMVSMQKLKEIAPKMKELQEKYKDEPQK
LQAHMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLLMGASMYWHQSVTP
SSVTDPMQAKLFKFLPLLFTIFLITFPAGLVLYWTTNNILSVLQQLIINKVLENKKRMHAQNKKES

Sequences:

>Translated_546_residues
MDKNNNANIRLILAIALSFLFIAIYSYFFQKPNKTTTPTTKQETTNNHTTTNPNTPNAFNATQAIPQENLLSTISFEHAR
IEIDSLGRIKQVYLKDKKYLTPKQKGFLEHVSHLFNPKANPQTPLKELPLLAADKLKPLEVRFLDPTLNNKAFNTPYSAS
KTTLGPNEQLVLTQDLGALTIIKTLTFYDDLHYDLQIAFKSPNKIIPSYVITNGYKPVADLDSYTFSGVLLENNDKKIEK
IEDKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEALIDSEIGTKNPLGFISLKNEANLHGYIGPKDYRSLKAISPM
LTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIILLTIIVRLILYPLSYKGMVSMQKLKEIAPKMKELQEKYKDEPQK
LQAHMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLLMGASMYWHQSVTP
SSVTDPMQAKLFKFLPLLFTIFLITFPAGLVLYWTTNNILSVLQQLIINKVLENKKRMHAQNKKES
>Mature_546_residues
MDKNNNANIRLILAIALSFLFIAIYSYFFQKPNKTTTPTTKQETTNNHTTTNPNTPNAFNATQAIPQENLLSTISFEHAR
IEIDSLGRIKQVYLKDKKYLTPKQKGFLEHVSHLFNPKANPQTPLKELPLLAADKLKPLEVRFLDPTLNNKAFNTPYSAS
KTTLGPNEQLVLTQDLGALTIIKTLTFYDDLHYDLQIAFKSPNKIIPSYVITNGYKPVADLDSYTFSGVLLENNDKKIEK
IEDKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEALIDSEIGTKNPLGFISLKNEANLHGYIGPKDYRSLKAISPM
LTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIILLTIIVRLILYPLSYKGMVSMQKLKEIAPKMKELQEKYKDEPQK
LQAHMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLLMGASMYWHQSVTP
SSVTDPMQAKLFKFLPLLFTIFLITFPAGLVLYWTTNNILSVLQQLIINKVLENKKRMHAQNKKES

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=337, Percent_Identity=36.7952522255193, Blast_Score=249, Evalue=3e-67,
Organism=Drosophila melanogaster, GI24662345, Length=196, Percent_Identity=27.5510204081633, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356443, Length=196, Percent_Identity=27.5510204081633, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 62431; Mature: 62431

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNNNANIRLILAIALSFLFIAIYSYFFQKPNKTTTPTTKQETTNNHTTTNPNTPNAFN
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ATQAIPQENLLSTISFEHARIEIDSLGRIKQVYLKDKKYLTPKQKGFLEHVSHLFNPKAN
HHHCCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
PQTPLKELPLLAADKLKPLEVRFLDPTLNNKAFNTPYSASKTTLGPNEQLVLTQDLGALT
CCCCHHHCCCHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHH
IIKTLTFYDDLHYDLQIAFKSPNKIIPSYVITNGYKPVADLDSYTFSGVLLENNDKKIEK
HHHHHHHHHCCCEEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHH
IEDKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEALIDSEIGTKNPLGFISLKNEA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEEEECCCC
NLHGYIGPKDYRSLKAISPMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIILLTI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IVRLILYPLSYKGMVSMQKLKEIAPKMKELQEKYKDEPQKLQAHMMQLYKKHGANPLGGC
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHH
LPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLLMGASMYWHQSVTP
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHCCHHHHHHHHHCCHHHHCCCCCC
SSVTDPMQAKLFKFLPLLFTIFLITFPAGLVLYWTTNNILSVLQQLIINKVLENKKRMHA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
QNKKES
CCCCCC
>Mature Secondary Structure
MDKNNNANIRLILAIALSFLFIAIYSYFFQKPNKTTTPTTKQETTNNHTTTNPNTPNAFN
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ATQAIPQENLLSTISFEHARIEIDSLGRIKQVYLKDKKYLTPKQKGFLEHVSHLFNPKAN
HHHCCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
PQTPLKELPLLAADKLKPLEVRFLDPTLNNKAFNTPYSASKTTLGPNEQLVLTQDLGALT
CCCCHHHCCCHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHH
IIKTLTFYDDLHYDLQIAFKSPNKIIPSYVITNGYKPVADLDSYTFSGVLLENNDKKIEK
HHHHHHHHHCCCEEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHH
IEDKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEALIDSEIGTKNPLGFISLKNEA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEEEECCCC
NLHGYIGPKDYRSLKAISPMLTDVIEYGLITFFAKGVFVLLDYLYQFVGNWGWAIILLTI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IVRLILYPLSYKGMVSMQKLKEIAPKMKELQEKYKDEPQKLQAHMMQLYKKHGANPLGGC
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHH
LPLILQIPVFFAIYRVLYNAVELKSSEWILWIHDLSIMDPYFILPLLMGASMYWHQSVTP
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHCCHHHHHHHHHCCHHHHCCCCCC
SSVTDPMQAKLFKFLPLLFTIFLITFPAGLVLYWTTNNILSVLQQLIINKVLENKKRMHA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
QNKKES
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]