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The map label for this gene is nadA [H]

Identifier: 188528145

GI number: 188528145

Start: 1362780

End: 1363790

Strand: Reverse

Name: nadA [H]

Synonym: HPSH_07020

Alternate gene names: 188528145

Gene position: 1363790-1362780 (Counterclockwise)

Preceding gene: 188528146

Following gene: 188528144

Centisome position: 84.78

GC content: 39.47

Gene sequence:

>1011_bases
ATGCCAACTGATAACGATTTAAAAACTTCTATTGTGGAATTATTGCGCGATTTAGACGCGCTTTTAGTGGCTCATTTTTA
TCAAAAAGATGAGATTGTGGAGTTGGCCCATTATACAGGCGATAGCCTAGAGTTAGCCAAAATCGCAAGCCAAAGCGATA
AAAACCTCATCGTGTTTTGTGGGGTGCATTTTATGGGTGAGAGCGTGAAAGCCCTAGCCTTTAACAAACAAGTGATCATG
CCCAAACTCTCATGCTGTTCTATGGCGAGAATGATTGATAGCCATTACTACGATAGAAGCGTTCATTTATTAAAAGAATA
CGGCGTTAAAGAGTTTTACCCTATCACTTATATCAATTCTAACGCTGAAGTGAAAGCCAAAGTCGCTAAAGATGGTGGCG
TGGTCTGCACGAGTCGCAACGCTTCTAAAATCTTTAATCACGCTTTAAAACAAAATAAAAAAATCTTTTTTCTACCGGAT
AAATGCTTGGGGGAAAATCTAGCCCTAGAAAATGGCTTAAAAAGCGCGATTTTAGGCGCAAATAGCAAAGAAGAAATTAA
AAACGCTGATGTGGTTTGTTATAACGGCTTTTGTTCGGTGCATCAGCTTTTCAAATTAGAAGATATTGAATTTTACCGCC
AAAAATACCCGGATATTTTAATCGCTGTCCATCCAGAATGCGAGCCTAGCGTGGTCCAAAATGCTGATTTTAGCGGATCA
ACGAGTCAAATCATAGAATTTGTAGAAAAGTTAAGCCCCCATCAAAAAGTCGCCATAGGCACTGAAAGCAATTTAGTCAA
TCGCTTGAAAGCCAAGCGCAACCATCAAAACACTTTCATTCTTTCTAGCACGCTCGCTCTTTGCCCCACCATGAATGAAA
CGACTTTAAAAGATTTGTTTGAAGTCTTAAAGGCTTATAAAAACCACAGGGCTTTTAACGCGATTGAATTAAAAGATGAG
GTGGCGCGTTTGGCCAAACTCGCTTTAACTAAAATGATGGAGTTGTCCTAA

Upstream 100 bases:

>100_bases
TTTGAAATGGGCTCTACGATCGTTTTATTCGTTCAAAACACCGCTTTTAAAGATTTGAAAGAAAAAAGCGTGAAGTTTGG
GGAAAGTATAGGGGAATTTC

Downstream 100 bases:

>100_bases
TGGAAATTAAAACCTTTTTAGAATGCGCTTTAAAAGAAGATTTAGGGCATGGGGATTTGTTTGAAAGGGTGTTAGAAAAA
GACTTTAAAGCCACAGCCTT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MPTDNDLKTSIVELLRDLDALLVAHFYQKDEIVELAHYTGDSLELAKIASQSDKNLIVFCGVHFMGESVKALAFNKQVIM
PKLSCCSMARMIDSHYYDRSVHLLKEYGVKEFYPITYINSNAEVKAKVAKDGGVVCTSRNASKIFNHALKQNKKIFFLPD
KCLGENLALENGLKSAILGANSKEEIKNADVVCYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVQNADFSGS
TSQIIEFVEKLSPHQKVAIGTESNLVNRLKAKRNHQNTFILSSTLALCPTMNETTLKDLFEVLKAYKNHRAFNAIELKDE
VARLAKLALTKMMELS

Sequences:

>Translated_336_residues
MPTDNDLKTSIVELLRDLDALLVAHFYQKDEIVELAHYTGDSLELAKIASQSDKNLIVFCGVHFMGESVKALAFNKQVIM
PKLSCCSMARMIDSHYYDRSVHLLKEYGVKEFYPITYINSNAEVKAKVAKDGGVVCTSRNASKIFNHALKQNKKIFFLPD
KCLGENLALENGLKSAILGANSKEEIKNADVVCYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVQNADFSGS
TSQIIEFVEKLSPHQKVAIGTESNLVNRLKAKRNHQNTFILSSTLALCPTMNETTLKDLFEVLKAYKNHRAFNAIELKDE
VARLAKLALTKMMELS
>Mature_335_residues
PTDNDLKTSIVELLRDLDALLVAHFYQKDEIVELAHYTGDSLELAKIASQSDKNLIVFCGVHFMGESVKALAFNKQVIMP
KLSCCSMARMIDSHYYDRSVHLLKEYGVKEFYPITYINSNAEVKAKVAKDGGVVCTSRNASKIFNHALKQNKKIFFLPDK
CLGENLALENGLKSAILGANSKEEIKNADVVCYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVQNADFSGST
SQIIEFVEKLSPHQKVAIGTESNLVNRLKAKRNHQNTFILSSTLALCPTMNETTLKDLFEVLKAYKNHRAFNAIELKDEV
ARLAKLALTKMMELS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=352, Percent_Identity=28.125, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37790; Mature: 37659

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTDNDLKTSIVELLRDLDALLVAHFYQKDEIVELAHYTGDSLELAKIASQSDKNLIVFC
CCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEE
GVHFMGESVKALAFNKQVIMPKLSCCSMARMIDSHYYDRSVHLLKEYGVKEFYPITYINS
CHHHHCCCHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
NAEVKAKVAKDGGVVCTSRNASKIFNHALKQNKKIFFLPDKCLGENLALENGLKSAILGA
CCEEEEEEECCCCEEEECCCHHHHHHHHHHCCCEEEEECHHHCCCCHHHHHCHHHHHCCC
NSKEEIKNADVVCYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVQNADFSGS
CCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCCCCC
TSQIIEFVEKLSPHQKVAIGTESNLVNRLKAKRNHQNTFILSSTLALCPTMNETTLKDLF
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCHHHHHHHH
EVLKAYKNHRAFNAIELKDEVARLAKLALTKMMELS
HHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTDNDLKTSIVELLRDLDALLVAHFYQKDEIVELAHYTGDSLELAKIASQSDKNLIVFC
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEE
GVHFMGESVKALAFNKQVIMPKLSCCSMARMIDSHYYDRSVHLLKEYGVKEFYPITYINS
CHHHHCCCHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
NAEVKAKVAKDGGVVCTSRNASKIFNHALKQNKKIFFLPDKCLGENLALENGLKSAILGA
CCEEEEEEECCCCEEEECCCHHHHHHHHHHCCCEEEEECHHHCCCCHHHHHCHHHHHCCC
NSKEEIKNADVVCYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVQNADFSGS
CCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCCCCC
TSQIIEFVEKLSPHQKVAIGTESNLVNRLKAKRNHQNTFILSSTLALCPTMNETTLKDLF
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCHHHHHHHH
EVLKAYKNHRAFNAIELKDEVARLAKLALTKMMELS
HHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA