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The map label for this gene is nusG

Identifier: 188527990

GI number: 188527990

Start: 1229415

End: 1229942

Strand: Reverse

Name: nusG

Synonym: HPSH_06225

Alternate gene names: 188527990

Gene position: 1229942-1229415 (Counterclockwise)

Preceding gene: 188527991

Following gene: 188527989

Centisome position: 76.46

GC content: 39.77

Gene sequence:

>528_bases
ATGGATTGGTATGCCATACAAACTTATTCAGGGAGCGAGCAGTCCGTTAAGAAAGCGATTGAGAATCTAGCGAACGATCA
TAATATAAGAGATAGGATACAAGAGATCATTGTGCCTACTGAAGATATTATAGAGGTTTCTAAAAAAAGCAAGACGAAAG
TAACGGAACGAAGCCTTTATCCTGGGTATGTTTTTATTAAAGTGGATTTAGATACGGTTTTGTGGCATAAGATACAATCT
TTGCCAAGAGTGAGCCGTTTTATTGGAGAAAACAAAAAGCCAACCCCGTTGAGTGAAGCGGATATTGGGCATATTTTAGA
AAAAATGAATAACCGAGCAGCCCCCAAGCCAAAAATCTTTTTTGAGCAAGGCGAAGTGGTGCGTGTGGTGGAAGGTCCTT
TTGCGAACTTTACCGCTACGGTGGAAGAGTATGATGTGGAACACCGCAAGCTCAAGCTCAATGTTTCTATTTTTGGTAGG
AACACTCCAATAGAGATTTTGCATTCGCAAGTGGAAAAAATTATATAA

Upstream 100 bases:

>100_bases
TGAGTGCTATCACGCTGTTTTTAGCTTTGTTGGATTTTTCTCTAGGGGCTTTTGTCTCTAGTGTTCTATAGGTTGGTGGC
TTTAAATAAGGAGAATAATG

Downstream 100 bases:

>100_bases
CTTTTTAAGGAGAAAACATGGCTAAAAAAGTAGTCGGAGAAATCAAACTTCAAATCCCTGCCGGTAAGGCAAACCCTTCA
CCTCCCGTAGGGCCAGCGTT

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MDWYAIQTYSGSEQSVKKAIENLANDHNIRDRIQEIIVPTEDIIEVSKKSKTKVTERSLYPGYVFIKVDLDTVLWHKIQS
LPRVSRFIGENKKPTPLSEADIGHILEKMNNRAAPKPKIFFEQGEVVRVVEGPFANFTATVEEYDVEHRKLKLNVSIFGR
NTPIEILHSQVEKII

Sequences:

>Translated_175_residues
MDWYAIQTYSGSEQSVKKAIENLANDHNIRDRIQEIIVPTEDIIEVSKKSKTKVTERSLYPGYVFIKVDLDTVLWHKIQS
LPRVSRFIGENKKPTPLSEADIGHILEKMNNRAAPKPKIFFEQGEVVRVVEGPFANFTATVEEYDVEHRKLKLNVSIFGR
NTPIEILHSQVEKII
>Mature_175_residues
MDWYAIQTYSGSEQSVKKAIENLANDHNIRDRIQEIIVPTEDIIEVSKKSKTKVTERSLYPGYVFIKVDLDTVLWHKIQS
LPRVSRFIGENKKPTPLSEADIGHILEKMNNRAAPKPKIFFEQGEVVRVVEGPFANFTATVEEYDVEHRKLKLNVSIFGR
NTPIEILHSQVEKII

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=173, Percent_Identity=41.6184971098266, Blast_Score=152, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 20130; Mature: 20130

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWYAIQTYSGSEQSVKKAIENLANDHNIRDRIQEIIVPTEDIIEVSKKSKTKVTERSLY
CCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
PGYVFIKVDLDTVLWHKIQSLPRVSRFIGENKKPTPLSEADIGHILEKMNNRAAPKPKIF
CCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEE
FEQGEVVRVVEGPFANFTATVEEYDVEHRKLKLNVSIFGRNTPIEILHSQVEKII
ECCCCEEEEECCCCCCCEEHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MDWYAIQTYSGSEQSVKKAIENLANDHNIRDRIQEIIVPTEDIIEVSKKSKTKVTERSLY
CCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
PGYVFIKVDLDTVLWHKIQSLPRVSRFIGENKKPTPLSEADIGHILEKMNNRAAPKPKIF
CCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEE
FEQGEVVRVVEGPFANFTATVEEYDVEHRKLKLNVSIFGRNTPIEILHSQVEKII
ECCCCEEEEECCCCCCCEEHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]