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The map label for this gene is yicO [C]

Identifier: 188527961

GI number: 188527961

Start: 1193905

End: 1195212

Strand: Reverse

Name: yicO [C]

Synonym: HPSH_06080

Alternate gene names: 188527961

Gene position: 1195212-1193905 (Counterclockwise)

Preceding gene: 188527962

Following gene: 188527960

Centisome position: 74.3

GC content: 44.04

Gene sequence:

>1308_bases
ATGGGGTTTTTCAAGCTTAAAGAACACAACACTAACATTGCCACCGAGTTTAGAGCGGGTTTAACGACCTTTATCACCAT
GATTTACATCGTGCCCTTAAACGCTCTTATCCTTTCTCAAGCCAACATGCCTTATGAAGCCCTTTTGAGCGCAACGGCCA
TTATCACTATCTTATCGAGCGTGTTTAACGGGTTGTGGGCAAACACCCCCATCGCTATGAGCGTGGGATTAGGGCTATCA
GCTTATTTTAGCTTCGGGTTGGTTCAAGGGCTAAAACTCCCTTGGCAGAGCGCTTTAGGCATCGTAGCGCTCTCTGGAGC
GATTTTTGTGATTCTGTCTTTCACCAAATTTAGAAGTTGGGTCATGCGAAGCATTCCTAGCGATCTAAGGCGCGCGGTGA
GCGCGGGGATAGGGGCTTTTATCGCGTTTATTGGTCTTAAAGAAATGCATATTGTAGTTACCCATAAGGCTACGCTTGTA
ACTTTAGGCGATTTTAGCGATCCGCATGTGTTATTGGGGGTTGTGGGGATTGTTTTAACTTTTGCGCTCTACACGCTCAA
AATCAAGGGTTCTTTTATTATAGCGGTCTTAATCACTTCCATTCTCGCATGGGTTTTAAAGCTGGCTCCTTACCCTAGCG
AATTTTTTTCCATGCCCGCTAGCATTAGCCCTATCGCCTTTCAATTAGACTTTAAGGGCATTTTTTTTGATGCGAGTGGG
GCTTTCACTTTAGCGTTAGTACCAGTCATCATCACTTTTTTTGTAACCGATTTGTTTGATTCCTTAGGCACGCTTGCAGG
GATTGGCCACAAGACTGATTTTTTCAATGATGAAGAAAAAAACAAGGAATTAGAAAGGACTTTAGAAGCGGATGCGGTGG
CTTCCTTAGGGAGCGCGGTGGTGGGCGTTTCTACTACGACGGCTTTTATAGAAAGCGCAAGTGGAGTTGAAGAGGGGGGC
CGCACAGGGCTTACAGCGGTTTTTACCGGGCTATTTTTTGTTTTAACGCTCTTTTGCTTGCCTCTTTTAAAAGCCATTCC
CAGCAATGCGATTTACCCAGTGCTAGTGATAGTAGGGGTTTTGATGTTTAGCGTGTTAGAGGGGGTGAATTTTAAAGACA
TGGCCACTAGCGTTTCCACTTTTTTAACCGTGGTGATGATGCCTTTAACCTTTTCCATTACCGATGGCTTAGCCTTTGGC
TTTTTGTCTTATGGTATCATCAAATTAGTTCAAAAAGACTTCAAGGCGCTCAATTCGGGCATTATCATTCTCTGCATCAT
TTCTGTTTCTGTATTTATCTTTCGTTAA

Upstream 100 bases:

>100_bases
AATCAAGCGTCTTAAGGCAATTTAAAATAAAATAGCGCTAACATAACCCCAAAGCCCCTTATTAAATTAATCTATACCAA
ATAGTAAGGAGTTATCTAAC

Downstream 100 bases:

>100_bases
GCTCTTTTTAAAGAGCTTTGTATTTTTTACCCATTTTGTGGCTTTTTTCCTTAATTTGGGTAATTTATTATCTCAAAACA
ATTACAATAGCATTATTATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MGFFKLKEHNTNIATEFRAGLTTFITMIYIVPLNALILSQANMPYEALLSATAIITILSSVFNGLWANTPIAMSVGLGLS
AYFSFGLVQGLKLPWQSALGIVALSGAIFVILSFTKFRSWVMRSIPSDLRRAVSAGIGAFIAFIGLKEMHIVVTHKATLV
TLGDFSDPHVLLGVVGIVLTFALYTLKIKGSFIIAVLITSILAWVLKLAPYPSEFFSMPASISPIAFQLDFKGIFFDASG
AFTLALVPVIITFFVTDLFDSLGTLAGIGHKTDFFNDEEKNKELERTLEADAVASLGSAVVGVSTTTAFIESASGVEEGG
RTGLTAVFTGLFFVLTLFCLPLLKAIPSNAIYPVLVIVGVLMFSVLEGVNFKDMATSVSTFLTVVMMPLTFSITDGLAFG
FLSYGIIKLVQKDFKALNSGIIILCIISVSVFIFR

Sequences:

>Translated_435_residues
MGFFKLKEHNTNIATEFRAGLTTFITMIYIVPLNALILSQANMPYEALLSATAIITILSSVFNGLWANTPIAMSVGLGLS
AYFSFGLVQGLKLPWQSALGIVALSGAIFVILSFTKFRSWVMRSIPSDLRRAVSAGIGAFIAFIGLKEMHIVVTHKATLV
TLGDFSDPHVLLGVVGIVLTFALYTLKIKGSFIIAVLITSILAWVLKLAPYPSEFFSMPASISPIAFQLDFKGIFFDASG
AFTLALVPVIITFFVTDLFDSLGTLAGIGHKTDFFNDEEKNKELERTLEADAVASLGSAVVGVSTTTAFIESASGVEEGG
RTGLTAVFTGLFFVLTLFCLPLLKAIPSNAIYPVLVIVGVLMFSVLEGVNFKDMATSVSTFLTVVMMPLTFSITDGLAFG
FLSYGIIKLVQKDFKALNSGIIILCIISVSVFIFR
>Mature_434_residues
GFFKLKEHNTNIATEFRAGLTTFITMIYIVPLNALILSQANMPYEALLSATAIITILSSVFNGLWANTPIAMSVGLGLSA
YFSFGLVQGLKLPWQSALGIVALSGAIFVILSFTKFRSWVMRSIPSDLRRAVSAGIGAFIAFIGLKEMHIVVTHKATLVT
LGDFSDPHVLLGVVGIVLTFALYTLKIKGSFIIAVLITSILAWVLKLAPYPSEFFSMPASISPIAFQLDFKGIFFDASGA
FTLALVPVIITFFVTDLFDSLGTLAGIGHKTDFFNDEEKNKELERTLEADAVASLGSAVVGVSTTTAFIESASGVEEGGR
TGLTAVFTGLFFVLTLFCLPLLKAIPSNAIYPVLVIVGVLMFSVLEGVNFKDMATSVSTFLTVVMMPLTFSITDGLAFGF
LSYGIIKLVQKDFKALNSGIIILCIISVSVFIFR

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=427, Percent_Identity=38.4074941451991, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI1790150, Length=424, Percent_Identity=38.2075471698113, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1790499, Length=432, Percent_Identity=30.5555555555556, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI48994909, Length=424, Percent_Identity=29.7169811320755, Blast_Score=198, Evalue=6e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46785; Mature: 46654

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFFKLKEHNTNIATEFRAGLTTFITMIYIVPLNALILSQANMPYEALLSATAIITILSS
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VFNGLWANTPIAMSVGLGLSAYFSFGLVQGLKLPWQSALGIVALSGAIFVILSFTKFRSW
HHHHHHCCCCHHEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VMRSIPSDLRRAVSAGIGAFIAFIGLKEMHIVVTHKATLVTLGDFSDPHVLLGVVGIVLT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECEEEEEECCCCCHHHHHHHHHHHHH
FALYTLKIKGSFIIAVLITSILAWVLKLAPYPSEFFSMPASISPIAFQLDFKGIFFDASG
HHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEEECEEEEECCC
AFTLALVPVIITFFVTDLFDSLGTLAGIGHKTDFFNDEEKNKELERTLEADAVASLGSAV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
VGVSTTTAFIESASGVEEGGRTGLTAVFTGLFFVLTLFCLPLLKAIPSNAIYPVLVIVGV
HCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LMFSVLEGVNFKDMATSVSTFLTVVMMPLTFSITDGLAFGFLSYGIIKLVQKDFKALNSG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IIILCIISVSVFIFR
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
GFFKLKEHNTNIATEFRAGLTTFITMIYIVPLNALILSQANMPYEALLSATAIITILSS
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VFNGLWANTPIAMSVGLGLSAYFSFGLVQGLKLPWQSALGIVALSGAIFVILSFTKFRSW
HHHHHHCCCCHHEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VMRSIPSDLRRAVSAGIGAFIAFIGLKEMHIVVTHKATLVTLGDFSDPHVLLGVVGIVLT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECEEEEEECCCCCHHHHHHHHHHHHH
FALYTLKIKGSFIIAVLITSILAWVLKLAPYPSEFFSMPASISPIAFQLDFKGIFFDASG
HHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEEECEEEEECCC
AFTLALVPVIITFFVTDLFDSLGTLAGIGHKTDFFNDEEKNKELERTLEADAVASLGSAV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
VGVSTTTAFIESASGVEEGGRTGLTAVFTGLFFVLTLFCLPLLKAIPSNAIYPVLVIVGV
HCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LMFSVLEGVNFKDMATSVSTFLTVVMMPLTFSITDGLAFGFLSYGIIKLVQKDFKALNSG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IIILCIISVSVFIFR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]