| Definition | Helicobacter pylori Shi470, complete genome. |
|---|---|
| Accession | NC_010698 |
| Length | 1,608,548 |
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The map label for this gene is cheA [H]
Identifier: 188527843
GI number: 188527843
Start: 1075708
End: 1078152
Strand: Direct
Name: cheA [H]
Synonym: HPSH_05445
Alternate gene names: 188527843
Gene position: 1075708-1078152 (Clockwise)
Preceding gene: 188527842
Following gene: 188527844
Centisome position: 66.87
GC content: 43.35
Gene sequence:
>2445_bases ATGGATGATTTGCAAGAAATAATGGAAGACTTCTTGATTGAAGCCTTTGAAATGAACGAGCAATTGGATCAGGATTTAGT GGAATTGGAGCATAACCCTGAGGATTTGGACTTGCTCAATCGCATTTTTAGAGTCGCTCACACCATTAAGGGCTCTAGCT CGTTTTTGAATCTTAACATTCTCACGCGCCTCACGCACAACATGGAAGATGTCTTAAATCGCGCCAGAAAGGGCGAAATC AAAATCACGCCTGATATTATGGATGTCGTGTTGCGCTCCATTGATTTGATGAAAACCTTGCTCGTAACGATTAGAGATAC CGGCTCTGATACCAATAACGGCAAGGAAAACGAGATTGAAGAAGCGGTCAAACAGCTTCAGGCCATTACGAGCCAAAATT TAGAGGGCGCTAAAGAAACTTCAGGAACTAAAGAAGCCCCCAAAAAAGAAAATCAAGAAGAAGTGAAAAAAGAAGCGAAA GAAGAAAATAAAGAAGAAAATCAAGAAGACAAGGCAAAAGCCCCTACTGCAAAAAACCCCGCAAGCGATAACCCGCTAGC CGATGAGCCGGATTTGGATTACTCTAACATGAGCGCTGAAGAAGTGGAAGCGGAGATTGAACGGCTATTGAACAAACGCC AAGAGGCCGATAAAGAACGAAGAGCCCAAAAAAAGCAAGAAGCCAAACCCAAACAAGAAGTTACCCCCAAAACAGAAACC CCCAAAACAGAAACCCCCAAAGCCCCTAAAACCGAAACTAAAGCTAAGGCTAAAGCAGATACTGAAGAAAATAAAGCCCC CTCTATTGGCGTGGAGCAAACCGTTAGGGTGGATGTGCGCCGCTTGGATCATTTAATGAATTTAATCGGTGAGCTTGTGT TAGGTAAGAATCGCTTGATTAGGATTTATGGCGATGTGGAAGAACGCTATGATGGGGAAAAGTTTTTAGAGGAATTAAAC CAGGTGGTTTCTTCTATTTCAGCGGTAACGACAGACTTGCAGCTTGCGGTGATGAAAACCAGGATGCAACCAGTGGGCAA GGTGTTCAATAAATTCCCTCGCATGGTAAGGGATTTGAGCCGAGAATTAGGCAAAAGCATTGAATTAATCATTGAGGGCG AAGAAACCGAATTAGACAAATCCATTGTAGAAGAGATTGGCGATCCGCTCATTCACATTATCCGCAACTCATGCGATCAT GGGATTGAGCCTTTAGAAGAAAGAAGAAGGCTTAACAAGCCTGAAACCGGTAAAGTGCAATTGAGCGCGTATAATGAGGG TAACCACATTGTGATTAAAATCTCTGATGACGGCAAGGGGTTAGACCCTGTGATGCTTAAAGAAAAAGCGATTGAAAAAG GGGTGATTAGCGAAAGAGACGCTGAAGGCATGAGCGATAGGGAAGCGTTTAACCTCATTTTCAAGCCAGGCTTTTCTACC GCAAAAGTCGTTTCCAATGTTTCAGGCAGAGGCGTGGGCATGGATGTGGTGAAAACCAATATTGAAAAGCTCAATGGGAT CATTGAAATTGATTCAGAAGTGGGGGTAGGCACGACTCAAAAGCTTAAAATCCCTCTCACTCTGGCTATCATTCAAGCTT TACTCGTGGGCGTTCAAGAAGAATATTACGCTATCCCGCTTTCTTCAGTGTTAGAAACCGTGCGCATCAGCCAGGATGAA ATCTACACCGTTGATGGCAAGAGCGTGTTGCGTTTGAGAGATGAGGTGCTTTCTTTGGTGCGCCTTTCTGATATTTTTAA AGTGGATGCCATTTTGGAATCCAACTCAGATGTGTATGTGGTTATCATTGGCTTGGCCGATCAAAAAATTGGCGTGATCG TGGATTATTTAATCGGTCAAGAAGAAGTGGTCATCAAATCTTTAGGTTACTATCTTAAAAACACTAGAGGCATTGCTGGC GCTACGGTGAGAGGCGATGGGAAAATCACCCTTATTGTAGATGTGGGGGCGATGATGGATATGGCAAAAAGCATCAAGGT CAATATCACTACCTTGATGAACGAATCCGAAAACACCAAGAGCAAAAATTCTCCTAGCGATTATATTGTCTTAGCGATTG ATGACAGCAGCACGGACAGAGCGATTATCCGCAAATGTTTAAAACCATTAGGCATCACGCTTTTAGAGGCCTCTAACGGG TTAGAGGGCTTAGAAATGCTTAAAAATGGCGATAAAACCCCGGACGCTATTTTAGTGGATATTGAAATGCCTAAAATGGA CGGCTACACTTTCGCTTCTGAAGTGCGTAAATACAATAAATTCAAAAACCTGCCTTTGATTGCAGTAACCAGTCGGGTAA CTAAAACCGATAGGATGCGCGGCGTTGAATCCGGCATGACTGAATACATCACCAAACCTTATAGCGGTGAGTATTTAACC ACCGTAGTGAAACGCAGCATTAAATTAGAAGGAGGCGAATCGTGA
Upstream 100 bases:
>100_bases ATTCACCGAAGAAATTTCTAAGATTTTAGACAAGAATGCATAATTCTTTTTATAAAATTGTAAAATACTCTTATCTCAAA CGCTAAAAAGGGGTTTTAAA
Downstream 100 bases:
>100_bases GCAATCAATTAAAAGATCTATTTGAAAGACAAAAAGAAGCTAGTGCGGGTTCTAAACAAGAAGACAATGAAGAAATTTTG CAATTCATTGGCTTTATTAT
Product: autophosphorylating histidine kinase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 814; Mature: 814
Protein sequence:
>814_residues MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNILTRLTHNMEDVLNRARKGEI KITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIEEAVKQLQAITSQNLEGAKETSGTKEAPKKENQEEVKKEAK EENKEENQEDKAKAPTAKNPASDNPLADEPDLDYSNMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKPKQEVTPKTET PKTETPKAPKTETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYGDVEERYDGEKFLEELN QVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDH GIEPLEERRRLNKPETGKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFST AKVVSNVSGRGVGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLETVRISQDE IYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAG ATVRGDGKITLIVDVGAMMDMAKSIKVNITTLMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEASNG LEGLEMLKNGDKTPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITKPYSGEYLT TVVKRSIKLEGGES
Sequences:
>Translated_814_residues MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNILTRLTHNMEDVLNRARKGEI KITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIEEAVKQLQAITSQNLEGAKETSGTKEAPKKENQEEVKKEAK EENKEENQEDKAKAPTAKNPASDNPLADEPDLDYSNMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKPKQEVTPKTET PKTETPKAPKTETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYGDVEERYDGEKFLEELN QVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDH GIEPLEERRRLNKPETGKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFST AKVVSNVSGRGVGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLETVRISQDE IYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAG ATVRGDGKITLIVDVGAMMDMAKSIKVNITTLMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEASNG LEGLEMLKNGDKTPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITKPYSGEYLT TVVKRSIKLEGGES >Mature_814_residues MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNILTRLTHNMEDVLNRARKGEI KITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIEEAVKQLQAITSQNLEGAKETSGTKEAPKKENQEEVKKEAK EENKEENQEDKAKAPTAKNPASDNPLADEPDLDYSNMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKPKQEVTPKTET PKTETPKAPKTETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLIRIYGDVEERYDGEKFLEELN QVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMVRDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDH GIEPLEERRRLNKPETGKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFST AKVVSNVSGRGVGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQEEYYAIPLSSVLETVRISQDE IYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNSDVYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAG ATVRGDGKITLIVDVGAMMDMAKSIKVNITTLMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEASNG LEGLEMLKNGDKTPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITKPYSGEYLT TVVKRSIKLEGGES
Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]
COG id: COG0643
COG function: function code NT; Chemotaxis protein histidine kinase and related kinases
Gene ontology:
Cell location: Membrane (Potential). Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HPt domain [H]
Homologues:
Organism=Escherichia coli, GI1788197, Length=672, Percent_Identity=34.077380952381, Blast_Score=345, Evalue=6e-96, Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=31.9327731092437, Blast_Score=69, Evalue=2e-12, Organism=Escherichia coli, GI145693157, Length=123, Percent_Identity=30.0813008130081, Blast_Score=63, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR002545 - InterPro: IPR004358 - InterPro: IPR008207 - InterPro: IPR004105 - InterPro: IPR005467 - InterPro: IPR009082 - InterPro: IPR010808 [H]
Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 90831; Mature: 90831
Theoretical pI: Translated: 4.73; Mature: 4.73
Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00217 SUGAR_TRANSPORT_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNI CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHH LTRLTHNMEDVLNRARKGEIKITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIE HHHHHCCHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH EAVKQLQAITSQNLEGAKETSGTKEAPKKENQEEVKKEAKEENKEENQEDKAKAPTAKNP HHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCC ASDNPLADEPDLDYSNMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKPKQEVTPKTET CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC PKTETPKAPKTETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLI CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE RIYGDVEERYDGEKFLEELNQVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMVRDLS EEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRRLNKPETGKVQ HHHCCCEEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEE LSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFST EEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEECCCCCH AKVVSNVSGRGVGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQE HHHHHCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHH EYYAIPLSSVLETVRISQDEIYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNSDVYV HHEECCHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE VIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLIVDVGAMMD EEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECHHHHH MAKSIKVNITTLMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEASNG HHHHHEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCC LEGLEMLKNGDKTPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMR HHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH GVESGMTEYITKPYSGEYLTTVVKRSIKLEGGES HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC >Mature Secondary Structure MDDLQEIMEDFLIEAFEMNEQLDQDLVELEHNPEDLDLLNRIFRVAHTIKGSSSFLNLNI CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHH LTRLTHNMEDVLNRARKGEIKITPDIMDVVLRSIDLMKTLLVTIRDTGSDTNNGKENEIE HHHHHCCHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH EAVKQLQAITSQNLEGAKETSGTKEAPKKENQEEVKKEAKEENKEENQEDKAKAPTAKNP HHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCC ASDNPLADEPDLDYSNMSAEEVEAEIERLLNKRQEADKERRAQKKQEAKPKQEVTPKTET CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC PKTETPKAPKTETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGKNRLI CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE RIYGDVEERYDGEKFLEELNQVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMVRDLS EEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRRLNKPETGKVQ HHHCCCEEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEE LSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKPGFST EEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEECCCCCH AKVVSNVSGRGVGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLVGVQE HHHHHCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHH EYYAIPLSSVLETVRISQDEIYTVDGKSVLRLRDEVLSLVRLSDIFKVDAILESNSDVYV HHEECCHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE VIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITLIVDVGAMMD EEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEECHHHHH MAKSIKVNITTLMNESENTKSKNSPSDYIVLAIDDSSTDRAIIRKCLKPLGITLLEASNG HHHHHEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCC LEGLEMLKNGDKTPDAILVDIEMPKMDGYTFASEVRKYNKFKNLPLIAVTSRVTKTDRMR HHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH GVESGMTEYITKPYSGEYLTTVVKRSIKLEGGES HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1938941; 9384377 [H]