Click here to switch to the map view.

The map label for this gene is ycfF [C]

Identifier: 188527831

GI number: 188527831

Start: 1061704

End: 1062018

Strand: Reverse

Name: ycfF [C]

Synonym: HPSH_05385

Alternate gene names: 188527831

Gene position: 1062018-1061704 (Counterclockwise)

Preceding gene: 188527845

Following gene: 188527830

Centisome position: 66.02

GC content: 36.83

Gene sequence:

>315_bases
ATGAATGTGTTTGAAAAAATAATCCAAGGCGAAATCCCTTGTTCTAAGATTTTAGAAAACGAGCGTTTTTTATCCTTTTA
TGACATTAACCCTAAAGCTAAAGTGCATGCGTTAGTGATCCCCAAACAAAGCATTCAGGATTTTAATGGCATCACCCCAG
AGCTTATGGCGCAAATGACAAGTTTTATTTTTGAAGTGGTGGAAAAATTAGGCATCAAAGAAAAGGGCTACAAGCTTTTA
ACCAATGTGGGTAAAAACGCAGGCCAAGAGGTGATGCATTTGCATTTTCATATTTTGAGCGGGGATAAACATTAA

Upstream 100 bases:

>100_bases
CGCTCTATTAAGGTGTGCAATAACGATCCTTATATTTTATTTTTAAAAAGCTATAATACAACTTTAATAAAAGAAAAACC
TTAAAAGGGAGCAAAAAAGC

Downstream 100 bases:

>100_bases
AAGCGTTGGTGGTGTTTCATGCAAGCGTTTTTAAATAGGAGTTTTGCTCCCTTGCTCAATCCTAATGAGAGTCCTTTAGA
GCAGGTTAGATCCAGTATTA

Product: protein kinase C inhibitor (SP:P16436)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLL
TNVGKNAGQEVMHLHFHILSGDKH

Sequences:

>Translated_104_residues
MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLL
TNVGKNAGQEVMHLHFHILSGDKH
>Mature_104_residues
MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLL
TNVGKNAGQEVMHLHFHILSGDKH

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain

Homologues:

Organism=Homo sapiens, GI4885413, Length=103, Percent_Identity=37.8640776699029, Blast_Score=75, Evalue=8e-15,
Organism=Homo sapiens, GI14211923, Length=103, Percent_Identity=33.0097087378641, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1787346, Length=103, Percent_Identity=35.9223300970874, Blast_Score=72, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17506713, Length=103, Percent_Identity=37.8640776699029, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320078, Length=97, Percent_Identity=37.1134020618557, Blast_Score=63, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24581222, Length=103, Percent_Identity=34.9514563106796, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28574010, Length=103, Percent_Identity=34.9514563106796, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHIT_HELPJ (P64383)

Other databases:

- EMBL:   AE001439
- RefSeq:   NP_223694.1
- ProteinModelPortal:   P64383
- SMR:   P64383
- STRING:   P64383
- GeneID:   889616
- GenomeReviews:   AE001439_GR
- KEGG:   hpj:jhp0977
- eggNOG:   COG0537
- HOGENOM:   HBG743217
- OMA:   HVMGGPR
- ProtClustDB:   CLSK496328
- BioCyc:   HPYL85963:JHP0977-MONOMER
- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310
- Gene3D:   G3DSA:3.30.428.10
- PANTHER:   PTHR23089
- PRINTS:   PR00332

Pfam domain/function: PF01230 HIT; SSF54197 His_triad-like_motif

EC number: NA

Molecular weight: Translated: 11855; Mature: 11855

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00892 HIT_1; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMT
CCHHHHHHCCCCCHHHHHCCCCEEEEEECCCCCEEEEEECCHHHHHHCCCCCHHHHHHHH
SFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSGDKH
HHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHEECCCCC
>Mature Secondary Structure
MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMT
CCHHHHHHCCCCCHHHHHCCCCEEEEEECCCCCEEEEEECCHHHHHHCCCCCHHHHHHHH
SFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSGDKH
HHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682