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The map label for this gene is dorA [H]

Identifier: 188527828

GI number: 188527828

Start: 1057257

End: 1059647

Strand: Reverse

Name: dorA [H]

Synonym: HPSH_05370

Alternate gene names: 188527828

Gene position: 1059647-1057257 (Counterclockwise)

Preceding gene: 188527829

Following gene: 188527827

Centisome position: 65.88

GC content: 41.7

Gene sequence:

>2391_bases
ATGTCCATTTCACGCAGAAGTATCCTAACAAAAATCCCAATCGCACTCGCTAGTGCTAATGTTTTAAAAGCTGTTGGTGT
TTTTGAAAAAGTAGAATCCATTCCGCATGCAACGCATTTTGGCCCCTTTATCGCAAAGGTTCAAAATGGAGTGATTAAAG
ATATTATCCCCCAAAAGAGCGATTATAACCCTACCATGATGTTAAAAGCGATGGTTGATAGGGTGTATTCAGATAGTAGG
GTGAAGTATCCTTGCGTGCGTAAGAGCTTCTTAGAAAACAAAAAAAACCACAAAGAATTGCGCGGGAGAGAAGAGTTTGT
GCGCGTGAGTTGGGATGTGGCACTGGATTTGGCGGCTAAAAAGCTTAAAGAAATCCCTAAAGAAAACATCTATAATGCTA
GTTATGGTGGCTGGGGGCATGCGGGCAGCTTGCATCGTTGTCATCATTTGGCATGGCGTTTTTTTAACACGACTTTAGGG
GGGGCTATTGGCACTGATGGGGAATATGGCAATGGTGCGGCTGCAAAAATAAACCCTATGATTGTAGGGGATATGGAAGT
TTATTCGCAACAAACCACTCATGAAGAGATGATTAAAAATTGCAAGGTGTATGTCATGTGGGGGGCGGATTTATTCAAGT
GCAACCGCATTGATTATTTCGTGCCAAACCATGTCAATGATGGCTACTACCCTAAATATAAAAGAGCTGGTATCAAATTC
ATTAGTATCGATCCCATTTATACCGAAACCGCTCAAGCCTTTAGCGCTGAATGGATACCCATTCGCCCTAATACTGATGT
AGCGTTAATGCTAGGCATGATGCATTATCTTTACACGAGCAATCAATACGATAAAGCGTTTATCGCTAAATACACTGATG
GCTTTGATAAATTCTTACCCTATTTGCTAGGAGAGAGCGATAATGCGCCTAAGACTTTGGAGTGGGCGTCTCAAATCACT
GGAGTGAGCGCAGAAAAAATCAAAGAATTAGCGGATTTGTTTGTTTCTAAACGCACTTTTTTAGCGGGTAATTGGGCCAT
GCAAAGAGCTCAGTATGGCGAGCAACCTGATTGGGCGTTAATTGTTTTAGCCAGCATGATTGGTCAAGTGGGTTTATCTG
GTGGGGGCTTTGGCTTTTCTATGCATTATGGAGGAAACGCTCAAGCAAGCTCAGGGGCAAGAATTGTTCCGATGATTTCA
CAAGGGCATAATTCTGTAAAAAGCGTTATTCCAGCATCTAGAATTTCTGAAGCGATTTTAAATCCGGATAAAGAAATTGA
TTTTATGGGTAAAAAACTCAAATTGCCTAAAATCAAAATGATTTATAATTGTGGGGCGGATTTATTGGGGCATGAAGCTG
ATACAAACGAGCTGATTCGCGCTTTAAGGACCTTAGATTGCGTGATCGTGCATGAGCCTTGGTGGACGCCTACGGCAAAA
TTTGCTGATATTGTCTTTGCTTCCACTAGCACTATGGAAAGAGATGATATTACTTTTGGAGGGAGTTATTCTAAAAATGT
GGTTTATGCCATGCGTAAGGTGATAGAGCCTGTTTATGAATCTAAAGACGATTATGAGATTTTCAGACAGCTTGCTTTAC
GCATTGGGGGCAATGAAACAGAGCAGAAATTCACTGAATCTAAGAGTTATATGGAATGGATTAAGGGCCTTTATGAAAAA
AGCGATGGTCCTACTTTGAAATCGTTTGATCAGTTTTGGAGGGATGGCTTTGTGGAGTTTGAAATCCCTGAAAATGCGAG
AAAGTTTGTGCGTCATGCGAAATTCAGGCAAGACCCTATTAATAATAAGCTGGATACAGAGAGCGGGAAAATTCAAATTT
TTTCTCAAAAATGCGCGGATTTTAAACGGGCCGATTTTAAAGGGCATCCTACTTGGTTTGAGCCAGCTGAGTGGCTAGGC
TCTAAAATGGCTGAGATTTACCCGTTCCATTTAATCTCTCCGCACCCAAAATACCGTGTCAATTCACAGCTTGATAACAC
TTGGGTTAGGAATGTGTATAAAATTCAAGGCAGAGAGCCTGTAACGATCAACGAACTAGACGCTAATAAATTAGGCATTA
GGCATGGTGAAATTGTAGAAGTGTTTAACGCTAGGGGGAGGTTGTTAGCAGGGGCGTTTGTAACTAAGAATATCCGTCAA
GGGGTTTTGAGTATCCAAAAAGGGGCGTGGTATGACCCAGAAGATGTGGGGGTTAGAAACCCACGATGCAATGCAGGGCA
TGTGAATACACTCACTTCTTTACGCCCCACAAGCAGCATGACGCAAGCCATTTCAGCCAATACCGCCTTAGTTAATATCA
GAAAACTCAGAAGGTATGAATTAATCAAGCCCTATCATTCCATTTCAACACCAAGCATTATTGGGGCTTAA

Upstream 100 bases:

>100_bases
GTTTTAAACTAACACCCGGTCTTTGCGGGCTTATTAGCGGTAATTTATGTGAATATATGTTAGAATTTGGGGTATTTTAA
CAGAAGCTTGAAGGAGAACC

Downstream 100 bases:

>100_bases
AAGGAGTGAAAATACTAGCATGAGAGTGTTTTAGAAAGACTTGAGCGCTAAAGACTTGAGCGCTAGCCAAGCTAAAGCGT
AATTCTCAATTTTTATATTA

Product: biotin sulfoxide reductase (bisC)

Products: NA

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 796; Mature: 795

Protein sequence:

>796_residues
MSISRRSILTKIPIALASANVLKAVGVFEKVESIPHATHFGPFIAKVQNGVIKDIIPQKSDYNPTMMLKAMVDRVYSDSR
VKYPCVRKSFLENKKNHKELRGREEFVRVSWDVALDLAAKKLKEIPKENIYNASYGGWGHAGSLHRCHHLAWRFFNTTLG
GAIGTDGEYGNGAAAKINPMIVGDMEVYSQQTTHEEMIKNCKVYVMWGADLFKCNRIDYFVPNHVNDGYYPKYKRAGIKF
ISIDPIYTETAQAFSAEWIPIRPNTDVALMLGMMHYLYTSNQYDKAFIAKYTDGFDKFLPYLLGESDNAPKTLEWASQIT
GVSAEKIKELADLFVSKRTFLAGNWAMQRAQYGEQPDWALIVLASMIGQVGLSGGGFGFSMHYGGNAQASSGARIVPMIS
QGHNSVKSVIPASRISEAILNPDKEIDFMGKKLKLPKIKMIYNCGADLLGHEADTNELIRALRTLDCVIVHEPWWTPTAK
FADIVFASTSTMERDDITFGGSYSKNVVYAMRKVIEPVYESKDDYEIFRQLALRIGGNETEQKFTESKSYMEWIKGLYEK
SDGPTLKSFDQFWRDGFVEFEIPENARKFVRHAKFRQDPINNKLDTESGKIQIFSQKCADFKRADFKGHPTWFEPAEWLG
SKMAEIYPFHLISPHPKYRVNSQLDNTWVRNVYKIQGREPVTINELDANKLGIRHGEIVEVFNARGRLLAGAFVTKNIRQ
GVLSIQKGAWYDPEDVGVRNPRCNAGHVNTLTSLRPTSSMTQAISANTALVNIRKLRRYELIKPYHSISTPSIIGA

Sequences:

>Translated_796_residues
MSISRRSILTKIPIALASANVLKAVGVFEKVESIPHATHFGPFIAKVQNGVIKDIIPQKSDYNPTMMLKAMVDRVYSDSR
VKYPCVRKSFLENKKNHKELRGREEFVRVSWDVALDLAAKKLKEIPKENIYNASYGGWGHAGSLHRCHHLAWRFFNTTLG
GAIGTDGEYGNGAAAKINPMIVGDMEVYSQQTTHEEMIKNCKVYVMWGADLFKCNRIDYFVPNHVNDGYYPKYKRAGIKF
ISIDPIYTETAQAFSAEWIPIRPNTDVALMLGMMHYLYTSNQYDKAFIAKYTDGFDKFLPYLLGESDNAPKTLEWASQIT
GVSAEKIKELADLFVSKRTFLAGNWAMQRAQYGEQPDWALIVLASMIGQVGLSGGGFGFSMHYGGNAQASSGARIVPMIS
QGHNSVKSVIPASRISEAILNPDKEIDFMGKKLKLPKIKMIYNCGADLLGHEADTNELIRALRTLDCVIVHEPWWTPTAK
FADIVFASTSTMERDDITFGGSYSKNVVYAMRKVIEPVYESKDDYEIFRQLALRIGGNETEQKFTESKSYMEWIKGLYEK
SDGPTLKSFDQFWRDGFVEFEIPENARKFVRHAKFRQDPINNKLDTESGKIQIFSQKCADFKRADFKGHPTWFEPAEWLG
SKMAEIYPFHLISPHPKYRVNSQLDNTWVRNVYKIQGREPVTINELDANKLGIRHGEIVEVFNARGRLLAGAFVTKNIRQ
GVLSIQKGAWYDPEDVGVRNPRCNAGHVNTLTSLRPTSSMTQAISANTALVNIRKLRRYELIKPYHSISTPSIIGA
>Mature_795_residues
SISRRSILTKIPIALASANVLKAVGVFEKVESIPHATHFGPFIAKVQNGVIKDIIPQKSDYNPTMMLKAMVDRVYSDSRV
KYPCVRKSFLENKKNHKELRGREEFVRVSWDVALDLAAKKLKEIPKENIYNASYGGWGHAGSLHRCHHLAWRFFNTTLGG
AIGTDGEYGNGAAAKINPMIVGDMEVYSQQTTHEEMIKNCKVYVMWGADLFKCNRIDYFVPNHVNDGYYPKYKRAGIKFI
SIDPIYTETAQAFSAEWIPIRPNTDVALMLGMMHYLYTSNQYDKAFIAKYTDGFDKFLPYLLGESDNAPKTLEWASQITG
VSAEKIKELADLFVSKRTFLAGNWAMQRAQYGEQPDWALIVLASMIGQVGLSGGGFGFSMHYGGNAQASSGARIVPMISQ
GHNSVKSVIPASRISEAILNPDKEIDFMGKKLKLPKIKMIYNCGADLLGHEADTNELIRALRTLDCVIVHEPWWTPTAKF
ADIVFASTSTMERDDITFGGSYSKNVVYAMRKVIEPVYESKDDYEIFRQLALRIGGNETEQKFTESKSYMEWIKGLYEKS
DGPTLKSFDQFWRDGFVEFEIPENARKFVRHAKFRQDPINNKLDTESGKIQIFSQKCADFKRADFKGHPTWFEPAEWLGS
KMAEIYPFHLISPHPKYRVNSQLDNTWVRNVYKIQGREPVTINELDANKLGIRHGEIVEVFNARGRLLAGAFVTKNIRQG
VLSIQKGAWYDPEDVGVRNPRCNAGHVNTLTSLRPTSSMTQAISANTALVNIRKLRRYELIKPYHSISTPSIIGA

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=803, Percent_Identity=37.359900373599, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1787231, Length=774, Percent_Identity=39.6640826873385, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI145693196, Length=769, Percent_Identity=38.4915474642393, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI87081797, Length=748, Percent_Identity=31.1497326203209, Blast_Score=278, Evalue=1e-75,
Organism=Escherichia coli, GI1787870, Length=755, Percent_Identity=30.9933774834437, Blast_Score=265, Evalue=7e-72,
Organism=Escherichia coli, GI171474008, Length=757, Percent_Identity=28.9299867899604, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI3868721, Length=644, Percent_Identity=22.8260869565217, Blast_Score=113, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 89962; Mature: 89831

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISRRSILTKIPIALASANVLKAVGVFEKVESIPHATHFGPFIAKVQNGVIKDIIPQKS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCC
DYNPTMMLKAMVDRVYSDSRVKYPCVRKSFLENKKNHKELRGREEFVRVSWDVALDLAAK
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHCCHHHHEEEHHHHHHHHHHH
KLKEIPKENIYNASYGGWGHAGSLHRCHHLAWRFFNTTLGGAIGTDGEYGNGAAAKINPM
HHHHCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCE
IVGDMEVYSQQTTHEEMIKNCKVYVMWGADLFKCNRIDYFVPNHVNDGYYPKYKRAGIKF
EEECHHHHHHHCHHHHHHHCCEEEEEECCCEEEECCEEEECCCCCCCCCCCCHHHCCEEE
ISIDPIYTETAQAFSAEWIPIRPNTDVALMLGMMHYLYTSNQYDKAFIAKYTDGFDKFLP
EEECCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHH
YLLGESDNAPKTLEWASQITGVSAEKIKELADLFVSKRTFLAGNWAMQRAQYGEQPDWAL
HHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECHHHHHHHHCCCCCCHHH
IVLASMIGQVGLSGGGFGFSMHYGGNAQASSGARIVPMISQGHNSVKSVIPASRISEAIL
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEHHCCCHHHHHHCCHHHHHHHHC
NPDKEIDFMGKKLKLPKIKMIYNCGADLLGHEADTNELIRALRTLDCVIVHEPWWTPTAK
CCCCCHHHCCCCCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHCEEEEECCCCCCCHH
FADIVFASTSTMERDDITFGGSYSKNVVYAMRKVIEPVYESKDDYEIFRQLALRIGGNET
HHHEEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
EQKFTESKSYMEWIKGLYEKSDGPTLKSFDQFWRDGFVEFEIPENARKFVRHAKFRQDPI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCC
NNKLDTESGKIQIFSQKCADFKRADFKGHPTWFEPAEWLGSKMAEIYPFHLISPHPKYRV
CCCCCCCCCCEEEEEHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCC
NSQLDNTWVRNVYKIQGREPVTINELDANKLGIRHGEIVEVFNARGRLLAGAFVTKNIRQ
CCCHHHHHHHHHHEECCCCCCEEECCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHH
GVLSIQKGAWYDPEDVGVRNPRCNAGHVNTLTSLRPTSSMTQAISANTALVNIRKLRRYE
HHHHHHCCCCCCCHHCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHH
LIKPYHSISTPSIIGA
HHCHHHCCCCCCCCCC
>Mature Secondary Structure 
SISRRSILTKIPIALASANVLKAVGVFEKVESIPHATHFGPFIAKVQNGVIKDIIPQKS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCC
DYNPTMMLKAMVDRVYSDSRVKYPCVRKSFLENKKNHKELRGREEFVRVSWDVALDLAAK
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHCCHHHHEEEHHHHHHHHHHH
KLKEIPKENIYNASYGGWGHAGSLHRCHHLAWRFFNTTLGGAIGTDGEYGNGAAAKINPM
HHHHCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCE
IVGDMEVYSQQTTHEEMIKNCKVYVMWGADLFKCNRIDYFVPNHVNDGYYPKYKRAGIKF
EEECHHHHHHHCHHHHHHHCCEEEEEECCCEEEECCEEEECCCCCCCCCCCCHHHCCEEE
ISIDPIYTETAQAFSAEWIPIRPNTDVALMLGMMHYLYTSNQYDKAFIAKYTDGFDKFLP
EEECCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHH
YLLGESDNAPKTLEWASQITGVSAEKIKELADLFVSKRTFLAGNWAMQRAQYGEQPDWAL
HHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECHHHHHHHHCCCCCCHHH
IVLASMIGQVGLSGGGFGFSMHYGGNAQASSGARIVPMISQGHNSVKSVIPASRISEAIL
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEHHCCCHHHHHHCCHHHHHHHHC
NPDKEIDFMGKKLKLPKIKMIYNCGADLLGHEADTNELIRALRTLDCVIVHEPWWTPTAK
CCCCCHHHCCCCCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHCEEEEECCCCCCCHH
FADIVFASTSTMERDDITFGGSYSKNVVYAMRKVIEPVYESKDDYEIFRQLALRIGGNET
HHHEEEECCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
EQKFTESKSYMEWIKGLYEKSDGPTLKSFDQFWRDGFVEFEIPENARKFVRHAKFRQDPI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCC
NNKLDTESGKIQIFSQKCADFKRADFKGHPTWFEPAEWLGSKMAEIYPFHLISPHPKYRV
CCCCCCCCCCEEEEEHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCC
NSQLDNTWVRNVYKIQGREPVTINELDANKLGIRHGEIVEVFNARGRLLAGAFVTKNIRQ
CCCHHHHHHHHHHEECCCCCCEEECCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHH
GVLSIQKGAWYDPEDVGVRNPRCNAGHVNTLTSLRPTSSMTQAISANTALVNIRKLRRYE
HHHHHHCCCCCCCHHCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHH
LIKPYHSISTPSIIGA
HHCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8856102; 8890911; 8890912; 10835270; 10985771 [H]