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The map label for this gene is xerD [H]

Identifier: 188527674

GI number: 188527674

Start: 874998

End: 876074

Strand: Direct

Name: xerD [H]

Synonym: HPSH_04480

Alternate gene names: 188527674

Gene position: 874998-876074 (Clockwise)

Preceding gene: 188527671

Following gene: 188527680

Centisome position: 54.4

GC content: 29.06

Gene sequence:

>1077_bases
ATGAAAAAATCAAATGACAATAACGCACTCGCCAGAAGTCAAAGGGAGTTGTTTGTAGGGATTAGGGATTTTATTGTTTT
TAAATTTAAGCGTATGGTTGTTTTTAACGGAGTAAGGGATTTTACAAAAATGAGATTTTTGTCCATAGAATTAGAAAAAT
GCGAAAATATTAAAGATTTGGAAAAATTATGTCATACAATTTATAATCAAGGCACAAAGCATATTTTGATGATGCGTGTA
TTGTTTTTATTCTTTGACTATTTTTGCAAGAATTTGAAAGTTAAGCGATTGAGACTAATCAATGAAGAAATGCTTGTGAA
TTTTTTATTTGAGTTAGCTAAACAAAGAAAGATTAATTCAATGGCAAAATATGTAATGTATATTAGGCAATTTTTTGATT
ACTTGGATAGGACTAAACATTATGAATTTTATTTTAGTCTTAAAAATATAGCCTTTGCTAAACACAAGGATAATTTGCCT
AAACATCTAAATTCAAAAGATTTAAAATCTTTTGTATATACTCTTATAAACTATAGAACTAGAAGCAGTTATGAAAAGAG
AAATAAGTGTATTTTACTCTTAATTATTTTGGGTGGTTTGAGAAAATCTGAGGTTTTTAATTTAGAATTGAGAAATATTG
TTTTAGAGAAAGAGCATTATATCTTGCTTATAAAAGGCAAAAACAATAAAGAGCGAAAAGCGTTCATTAAACGAGAAATG
CTAGAAAAATCTTTAGATGAGTGGTTGGGTGATAGCAAACGATTGAGTAGTTTTAATGGGCGTTTTGTATTTAAGAAGTC
TTTGTCTAACTATACTCAAAAGTATTGTTCAATCAGTAATTTTGTGTTAAAGATTTTTATGTTGAGTGGTATTGAAAATT
TTAAACAATATGGCACAGGATTGCACCTATTTAGGCATAGTTTTGCCACTTTAGTCTATGCTAAGAGTAGGGATATTGTT
TTGACTTCAAGAGCATTGGGGCATCAGTCCTTAAGCTCCACAAAAATCTACATTCACACCGCACAAGAATATAATAAACA
AGTAGCAAGCATTTTTGATAATTTGTTGAGTGGGTGA

Upstream 100 bases:

>100_bases
TTTTTATTCTTTTTTTATAAATAAGCTCCTTGTTTTTGATTTTTTATAAATTACATTCTTTTTGATTTCTATTGAAAAAT
TTAATATTAAGAGGACTTTT

Downstream 100 bases:

>100_bases
AAGATGGTTAATTTCCTCATTCAAAAATTCTTTAAAAGGTTGTTTTTTGATGTTTTTTTGCAGTTTATCTCGTTGCTTTA
GAACCAACATTAACAAAACC

Product: integrase/recombinase (xerD)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKKSNDNNALARSQRELFVGIRDFIVFKFKRMVVFNGVRDFTKMRFLSIELEKCENIKDLEKLCHTIYNQGTKHILMMRV
LFLFFDYFCKNLKVKRLRLINEEMLVNFLFELAKQRKINSMAKYVMYIRQFFDYLDRTKHYEFYFSLKNIAFAKHKDNLP
KHLNSKDLKSFVYTLINYRTRSSYEKRNKCILLLIILGGLRKSEVFNLELRNIVLEKEHYILLIKGKNNKERKAFIKREM
LEKSLDEWLGDSKRLSSFNGRFVFKKSLSNYTQKYCSISNFVLKIFMLSGIENFKQYGTGLHLFRHSFATLVYAKSRDIV
LTSRALGHQSLSSTKIYIHTAQEYNKQVASIFDNLLSG

Sequences:

>Translated_358_residues
MKKSNDNNALARSQRELFVGIRDFIVFKFKRMVVFNGVRDFTKMRFLSIELEKCENIKDLEKLCHTIYNQGTKHILMMRV
LFLFFDYFCKNLKVKRLRLINEEMLVNFLFELAKQRKINSMAKYVMYIRQFFDYLDRTKHYEFYFSLKNIAFAKHKDNLP
KHLNSKDLKSFVYTLINYRTRSSYEKRNKCILLLIILGGLRKSEVFNLELRNIVLEKEHYILLIKGKNNKERKAFIKREM
LEKSLDEWLGDSKRLSSFNGRFVFKKSLSNYTQKYCSISNFVLKIFMLSGIENFKQYGTGLHLFRHSFATLVYAKSRDIV
LTSRALGHQSLSSTKIYIHTAQEYNKQVASIFDNLLSG
>Mature_358_residues
MKKSNDNNALARSQRELFVGIRDFIVFKFKRMVVFNGVRDFTKMRFLSIELEKCENIKDLEKLCHTIYNQGTKHILMMRV
LFLFFDYFCKNLKVKRLRLINEEMLVNFLFELAKQRKINSMAKYVMYIRQFFDYLDRTKHYEFYFSLKNIAFAKHKDNLP
KHLNSKDLKSFVYTLINYRTRSSYEKRNKCILLLIILGGLRKSEVFNLELRNIVLEKEHYILLIKGKNNKERKAFIKREM
LEKSLDEWLGDSKRLSSFNGRFVFKKSLSNYTQKYCSISNFVLKIFMLSGIENFKQYGTGLHLFRHSFATLVYAKSRDIV
LTSRALGHQSLSSTKIYIHTAQEYNKQVASIFDNLLSG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=234, Percent_Identity=28.6324786324786, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 42657; Mature: 42657

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSNDNNALARSQRELFVGIRDFIVFKFKRMVVFNGVRDFTKMRFLSIELEKCENIKDL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCHHHH
EKLCHTIYNQGTKHILMMRVLFLFFDYFCKNLKVKRLRLINEEMLVNFLFELAKQRKINS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAKYVMYIRQFFDYLDRTKHYEFYFSLKNIAFAKHKDNLPKHLNSKDLKSFVYTLINYRT
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
RSSYEKRNKCILLLIILGGLRKSEVFNLELRNIVLEKEHYILLIKGKNNKERKAFIKREM
HCCHHHHCCEEEEEEECCCCCCCCEEEHHHHHHEEECCCEEEEEECCCCHHHHHHHHHHH
LEKSLDEWLGDSKRLSSFNGRFVFKKSLSNYTQKYCSISNFVLKIFMLSGIENFKQYGTG
HHHHHHHHCCCCHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LHLFRHSFATLVYAKSRDIVLTSRALGHQSLSSTKIYIHTAQEYNKQVASIFDNLLSG
HHHHHHHHHHHHEECCCCEEEEEHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKSNDNNALARSQRELFVGIRDFIVFKFKRMVVFNGVRDFTKMRFLSIELEKCENIKDL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCHHHH
EKLCHTIYNQGTKHILMMRVLFLFFDYFCKNLKVKRLRLINEEMLVNFLFELAKQRKINS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAKYVMYIRQFFDYLDRTKHYEFYFSLKNIAFAKHKDNLPKHLNSKDLKSFVYTLINYRT
HHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
RSSYEKRNKCILLLIILGGLRKSEVFNLELRNIVLEKEHYILLIKGKNNKERKAFIKREM
HCCHHHHCCEEEEEEECCCCCCCCEEEHHHHHHEEECCCEEEEEECCCCHHHHHHHHHHH
LEKSLDEWLGDSKRLSSFNGRFVFKKSLSNYTQKYCSISNFVLKIFMLSGIENFKQYGTG
HHHHHHHHCCCCHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LHLFRHSFATLVYAKSRDIVLTSRALGHQSLSSTKIYIHTAQEYNKQVASIFDNLLSG
HHHHHHHHHHHHEECCCCEEEEEHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]