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The map label for this gene is glnA [H]

Identifier: 188527651

GI number: 188527651

Start: 852479

End: 853924

Strand: Direct

Name: glnA [H]

Synonym: HPSH_04365

Alternate gene names: 188527651

Gene position: 852479-853924 (Clockwise)

Preceding gene: 188527644

Following gene: 188527658

Centisome position: 53.0

GC content: 43.02

Gene sequence:

>1446_bases
ATGGTAGTAAGAACTCAAAATAGTGAAAGCAAGATCAAAGAATTTTTTGAATTTTGCAAAGAAAATGAAGTGGAATTTGT
GGATTTTAGATTCAGCGATATTAAAGGCACTTGGAATCACATCGCTTATTCTTTTGGGGCTTTAACGCATGGCATGTTTA
AAGAGGGGATTCCTTTTGATGCGAGTTGTTTTAAAGGCTGGCAAGGCATTGAACACTCCGATATGATTTTAACCCCTGAT
TTGGTGCGTTATTTCATTGACCCTTTTAGCGCGGATGTGAGCGTGGTCGTGTTTTGCGATGTGTATGATGTGTATAAAAA
CCAGCCTTATGAGAAATGCCCTAGAAGTATCGCTAAAAAAGCCTTACAGCATTTAAAAGATTCAGGTTTGGGCGATGTGG
CTTATTTTGGCGCAGAGAGCGAATTTTTCATCTTTGATTCCATTAAGATTAAAGACGCTTCCAATTCCCAATACTACGAA
GTGGATAGCGAAGAGGGCGAATGGAATAGGGATAAGAGCTTTGAAAATGGCGTGAATTTTGGGCACAGACCGGGCAAGCA
AGGGGGCTATCTGCCTGTGCCGCCAACGGATACGATGATGGATATTCGCACAGAAATTGTGAAAGTCTTAAACCAAGTGG
GGTTAGAAACTTTTGTCGTCCATCATGAAGTCGCGCAAGCGCAAGGCGAAGTGGGCGTGAAATTTGGGGATTTAGTGGAA
GCCGCTGACAATGTCCAAAAACTCAAATATGTGGTTAAAATGGTCGCTCATTTAAACGGCAAAACCGCCACTTTCATGCC
AAAACCTTTATATGGGGATAACGGGAGTGGGATGCACACCCATGTGAGTGTTTGGAAAAACAACGAAAACCTTTTTAGCG
GCGAAACTTACAAGGGCTTGAGCGAGTTGGCGTTGCATTTTTTAGGGGGCGTGTTGCGCCACGCTAGAGGGTTAGCCGCT
TTCACTAACGCTTCCACTAATTCCTATAAACGCCTAATTCCTGGCTATGAAGCCCCATCTATTTTAACCTATTCGGCTAA
CAACAGGAGCGCGAGCGTGCGTATCCCTTATGGGATTTCTAAAAACAGCGCGAGGTTTGAATTCAGGTTTCCTGACAGCT
CATCAAACCCCTACTTGGCTTTTTCAGCGATTTTAATGGCAGGCATGGATGGCGTTAAAAACAAGATCGATCCCGGCGAA
GCGATGGATATTAACCTTTTCAAATTGACTTTAGATGAAATCAGAGAAAAGGGTATCAAGCAAATGCCCCACACCTTAAG
GAGCTCGTTAGAAGAAATGCTAGCCGATAAGCGGTATTTAAAAGAGGGTCAGGTCTTTAGCGAAGAATTTATTCAAGCCT
ATCAGTCTCTTAAATTCAACGCTGAAGTGTTCCCATGGGAGAGCAAACCCCATCCTTTTGAATTTATCACCACTTATTCA
TGCTAA

Upstream 100 bases:

>100_bases
ATCTTAATAAAACTTGATACAGATTTCACTTTTTTTACCCCATAAATGCTATAATCACCCCTATCAATCAAACTCAATTC
ATAACAATTAAAGGTGGTTA

Downstream 100 bases:

>100_bases
AACAATGAGCGGATCAATAATCCCCTTTTAAAAATTTAGAATAAGGCAAAAATGCCTTGTTCTTAAAAATGGGGTTGAAA
AAATTTATTTTCTTTATTTT

Product: glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MVVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFDASCFKGWQGIEHSDMILTPD
LVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKKALQHLKDSGLGDVAYFGAESEFFIFDSIKIKDASNSQYYE
VDSEEGEWNRDKSFENGVNFGHRPGKQGGYLPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
AADNVQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSVWKNNENLFSGETYKGLSELALHFLGGVLRHARGLAA
FTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGISKNSARFEFRFPDSSSNPYLAFSAILMAGMDGVKNKIDPGE
AMDINLFKLTLDEIREKGIKQMPHTLRSSLEEMLADKRYLKEGQVFSEEFIQAYQSLKFNAEVFPWESKPHPFEFITTYS
C

Sequences:

>Translated_481_residues
MVVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFDASCFKGWQGIEHSDMILTPD
LVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKKALQHLKDSGLGDVAYFGAESEFFIFDSIKIKDASNSQYYE
VDSEEGEWNRDKSFENGVNFGHRPGKQGGYLPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
AADNVQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSVWKNNENLFSGETYKGLSELALHFLGGVLRHARGLAA
FTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGISKNSARFEFRFPDSSSNPYLAFSAILMAGMDGVKNKIDPGE
AMDINLFKLTLDEIREKGIKQMPHTLRSSLEEMLADKRYLKEGQVFSEEFIQAYQSLKFNAEVFPWESKPHPFEFITTYS
C
>Mature_481_residues
MVVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFDASCFKGWQGIEHSDMILTPD
LVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKKALQHLKDSGLGDVAYFGAESEFFIFDSIKIKDASNSQYYE
VDSEEGEWNRDKSFENGVNFGHRPGKQGGYLPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
AADNVQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSVWKNNENLFSGETYKGLSELALHFLGGVLRHARGLAA
FTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGISKNSARFEFRFPDSSSNPYLAFSAILMAGMDGVKNKIDPGE
AMDINLFKLTLDEIREKGIKQMPHTLRSSLEEMLADKRYLKEGQVFSEEFIQAYQSLKFNAEVFPWESKPHPFEFITTYS
C

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1790301, Length=465, Percent_Identity=49.0322580645161, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI87081870, Length=368, Percent_Identity=26.6304347826087, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641290, Length=332, Percent_Identity=25.6024096385542, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24641292, Length=332, Percent_Identity=25.6024096385542, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281360453, Length=323, Percent_Identity=26.625386996904, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17136208, Length=323, Percent_Identity=26.625386996904, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24580558, Length=323, Percent_Identity=26.625386996904, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 54372; Mature: 54372

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFD
CEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ASCFKGWQGIEHSDMILTPDLVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKK
HHHHHCCCCCCCCCEEECHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHH
ALQHLKDSGLGDVAYFGAESEFFIFDSIKIKDASNSQYYEVDSEEGEWNRDKSFENGVNF
HHHHHHHCCCCCEEEECCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCCCCHHHCCCC
GHRPGKQGGYLPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
CCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHH
AADNVQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSVWKNNENLFSGETYKGL
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHCCH
SELALHFLGGVLRHARGLAAFTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGIS
HHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHCCCCCCCCEEEEECCCCCEEEEECCCCC
KNSARFEFRFPDSSSNPYLAFSAILMAGMDGVKNKIDPGEAMDINLFKLTLDEIREKGIK
CCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHH
QMPHTLRSSLEEMLADKRYLKEGQVFSEEFIQAYQSLKFNAEVFPWESKPHPFEFITTYS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEECC
C
C
>Mature Secondary Structure
MVVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFD
CEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ASCFKGWQGIEHSDMILTPDLVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKK
HHHHHCCCCCCCCCEEECHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHH
ALQHLKDSGLGDVAYFGAESEFFIFDSIKIKDASNSQYYEVDSEEGEWNRDKSFENGVNF
HHHHHHHCCCCCEEEECCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCCCCHHHCCCC
GHRPGKQGGYLPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
CCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHH
AADNVQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSVWKNNENLFSGETYKGL
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHCCH
SELALHFLGGVLRHARGLAAFTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGIS
HHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHCCCCCCCCEEEEECCCCCEEEEECCCCC
KNSARFEFRFPDSSSNPYLAFSAILMAGMDGVKNKIDPGEAMDINLFKLTLDEIREKGIK
CCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHH
QMPHTLRSSLEEMLADKRYLKEGQVFSEEFIQAYQSLKFNAEVFPWESKPHPFEFITTYS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEECC
C
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]