| Definition | Helicobacter pylori Shi470, complete genome. |
|---|---|
| Accession | NC_010698 |
| Length | 1,608,548 |
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The map label for this gene is fabG
Identifier: 188527592
GI number: 188527592
Start: 793283
End: 794026
Strand: Direct
Name: fabG
Synonym: HPSH_04070
Alternate gene names: 188527592
Gene position: 793283-794026 (Clockwise)
Preceding gene: 188527591
Following gene: 188527593
Centisome position: 49.32
GC content: 43.15
Gene sequence:
>744_bases ATGCAATTCACAGGGAAAAATGTTCTCATTACTGGGGCTTCTAAAGGCATTGGGGCTGAAATCGCCAAAACTCTCGCTTC TATGGGGCTGAAAGTTTGGATCAATTACCGCAGTAATGCTGAAGTGGCTGACGCTTTAAAAAATGAACTTGAAGAAAAAG GCTATAAGGCAGCTGTCATTAAATTTGACGCGGCTTCTGAAAGCGACTTTGTTGAAGCGATACAGACCATTGTCCAAAGC GATGGAGGTTTGTCTTACTTGGTGAATAACGCCGGTGTGGTGCGCGATAAATTAGCGATCAAAATGAAAACAGAAGATTT TCACCATGTCATAGACAATAATCTCACTTCAGCCTTTATAGGTTGCCGAGAGGCTTTAAAGGTGATGAGCAAGAGTCGTT TTGGGAGCGTGGTCAATATCGCATCTATCATTGGTGAAAGAGGCAATATGGGGCAGACAAACTACTCAGCGAGTAAGGGA GGGATGATTGCGATGAGCAAGTCCTTTGCTTATGAGGGAGCTTTAAGGAATATTCGTTTCAACTCTGTGACGCCCGGTTT TATAGAAACCGACATGAACGCCAATTTGAAAGATGAACTCAAAGCGGATTATGTTAAAAACATTCCTTTAAACAGGCTAG GGTCTGCTAAAGAAGTGGCAGAAGCGGTAGCGTTTCTCTTGAGCGATCATTCTAGTTACATCACTGGAGAGACTCTCAAA GTCAATGGCGGGCTTTATATGTAG
Upstream 100 bases:
>100_bases CAGCGCTAAAAAGAAGGTTTTAAAGCGTCTTTATATGTTAAGGCGTTATGAGTCAAGACTATAATAAGCTTTGAGAAAAA TTTAAAAATTAAGGATAATC
Downstream 100 bases:
>100_bases TCCTAAACAAAGGATTCTTTAGCGATAAAAGTTTGTAAGTGGCAAAAATCATGCTAACATTATGAGGTTATTCTAAAACA AAGAGGTTATTATCAAATGG
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 247; Mature: 247
Protein sequence:
>247_residues MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAASESDFVEAIQTIVQS DGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRFGSVVNIASIIGERGNMGQTNYSASKG GMIAMSKSFAYEGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLK VNGGLYM
Sequences:
>Translated_247_residues MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAASESDFVEAIQTIVQS DGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRFGSVVNIASIIGERGNMGQTNYSASKG GMIAMSKSFAYEGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLK VNGGLYM >Mature_247_residues MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAASESDFVEAIQTIVQS DGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRFGSVVNIASIIGERGNMGQTNYSASKG GMIAMSKSFAYEGALRNIRFNSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLK VNGGLYM
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=40.7563025210084, Blast_Score=168, Evalue=4e-42, Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=35.6, Blast_Score=137, Evalue=1e-32, Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=32.6446280991736, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI4504505, Length=258, Percent_Identity=29.0697674418605, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=29.4820717131474, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=31.4516129032258, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=28.75, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=27.6, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI109715829, Length=228, Percent_Identity=29.3859649122807, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI59889578, Length=202, Percent_Identity=30.1980198019802, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=28.5140562248996, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=26.8774703557312, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI66933014, Length=171, Percent_Identity=26.9005847953216, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI4503301, Length=251, Percent_Identity=27.8884462151394, Blast_Score=74, Evalue=8e-14, Organism=Homo sapiens, GI33667109, Length=241, Percent_Identity=27.8008298755187, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=31.0734463276836, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=45.748987854251, Blast_Score=203, Evalue=8e-54, Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=38.4297520661157, Blast_Score=160, Evalue=1e-40, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=32.5396825396825, Blast_Score=126, Evalue=2e-30, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=31.9838056680162, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=29.5833333333333, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=29.5081967213115, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=31.0204081632653, Blast_Score=108, Evalue=2e-25, Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=28.3464566929134, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=29.0983606557377, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=31.4285714285714, Blast_Score=97, Evalue=8e-22, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=27.6, Blast_Score=83, Evalue=1e-17, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=25.5813953488372, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1787526, Length=240, Percent_Identity=25.8333333333333, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=38.3673469387755, Blast_Score=157, Evalue=5e-39, Organism=Caenorhabditis elegans, GI17555706, Length=260, Percent_Identity=38.0769230769231, Blast_Score=153, Evalue=9e-38, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=35.3174603174603, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17568967, Length=222, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=31.9391634980989, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=32.520325203252, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=30.952380952381, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=31.3492063492063, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=32.3886639676113, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=31.7073170731707, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=30.5343511450382, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=28.5171102661597, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=28.8973384030418, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=29.9595141700405, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=28.735632183908, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=27.9245283018868, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=27.1317829457364, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=30.188679245283, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=32.4607329842932, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=28.8973384030418, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=28.0769230769231, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=28.6259541984733, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=28.6259541984733, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=29.2490118577075, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=31.3131313131313, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=29.6153846153846, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=27.3684210526316, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=31.9587628865979, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=26.3358778625954, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=28.5140562248996, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17561272, Length=125, Percent_Identity=32, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=257, Percent_Identity=31.9066147859922, Blast_Score=108, Evalue=6e-25, Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=28.0632411067194, Blast_Score=82, Evalue=8e-17, Organism=Saccharomyces cerevisiae, GI6323882, Length=244, Percent_Identity=27.8688524590164, Blast_Score=63, Evalue=3e-11, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=35.2226720647773, Blast_Score=142, Evalue=2e-34, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=34.4, Blast_Score=125, Evalue=2e-29, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=33.7254901960784, Blast_Score=111, Evalue=6e-25, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=30.4, Blast_Score=111, Evalue=6e-25, Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=32.7868852459016, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.2, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=31.3253012048193, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI18859837, Length=246, Percent_Identity=29.6747967479675, Blast_Score=100, Evalue=9e-22, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=30.078125, Blast_Score=98, Evalue=6e-21, Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=30.5555555555556, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24641232, Length=238, Percent_Identity=27.3109243697479, Blast_Score=81, Evalue=5e-16, Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=29.7979797979798, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24665243, Length=206, Percent_Identity=28.6407766990291, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331218, Length=206, Percent_Identity=28.6407766990291, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=29.2307692307692, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24648944, Length=233, Percent_Identity=27.0386266094421, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI116007236, Length=234, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24665247, Length=207, Percent_Identity=28.0193236714976, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI221331216, Length=207, Percent_Identity=28.0193236714976, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=30.0518134715026, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI161076933, Length=194, Percent_Identity=30.4123711340206, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24641388, Length=237, Percent_Identity=26.1603375527426, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=30.9278350515464, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=30.9278350515464, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI28571387, Length=243, Percent_Identity=27.1604938271605, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26669; Mature: 26669
Theoretical pI: Translated: 8.38; Mature: 8.38
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVI CCCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEE KFDAASESDFVEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFI EECCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEECHHHHHHHHCCHHHHHH GCREALKVMSKSRFGSVVNIASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRF HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCEE NSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLK CCCCCCEEECCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCEECCCEEE VNGGLYM ECCCCCC >Mature Secondary Structure MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVI CCCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEE KFDAASESDFVEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFI EECCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEECHHHHHHHHCCHHHHHH GCREALKVMSKSRFGSVVNIASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRF HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCEE NSVTPGFIETDMNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGETLK CCCCCCEEECCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCEECCCEEE VNGGLYM ECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9537320 [H]