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The map label for this gene is mutSB [H]

Identifier: 188527529

GI number: 188527529

Start: 721885

End: 724134

Strand: Direct

Name: mutSB [H]

Synonym: HPSH_03755

Alternate gene names: 188527529

Gene position: 721885-724134 (Clockwise)

Preceding gene: 188527528

Following gene: 188527537

Centisome position: 44.88

GC content: 37.96

Gene sequence:

>2250_bases
ATGAATAATAATAATAATACCCCACCCAAACCCCTAGAAGAAAGCCTGGATTTAAAAGAGTTTATCGCTCTTTTTAAAAC
TTTTTTTGCAAAAGAAAGAGATACTATTGCTTTAGAAAACGATCTCAAGCAAACTTTCACTTATTTAAACGAAGTGGATG
CGATCGGTTTGCCTACCCCTAAAAGCGTGAAAGAAAGCAATCTCATTATCATCAAACTCACCAAATTAGGGACGCTCCAT
TTAGATGAAATTCATGAGATTGTCAAACGATTGCGCTACATTGTCATTCTACAAAACGCTTTTAAAACTTTCACGCATTT
AAAATTTCATGAACGCCTTAACGCTATTGTCCTGCCCCCTTTTTTTAATGATCTAATCGCTTTATTTGACGATGAGGGAA
AAATCAAACAAGGGGCTAACGCTACCCTAGACGCTTTGAATGAAAGTTTGAACCGCCTTAAAAAAGAGAGCGCTAAAATC
ATTCACCATTACGCCCATTCTAAAGAGCTTGCCCCTTATTTAGTGGATACGCAAAGCCACCTTAAGCATGGTTATGAATG
CCTTTTATTGAAAAGCGGGTTTTCTAGCGCGATTAAAGGCGTTGTGCTAGAAAGGAGCGCTAATGGCTATTTCTATCTTT
TGCCTGAAAGCGTGCAAAAAATCGCGCAAAAAATCGCACAAATTGATAATGAAATAGATTGCTGTATTGTTGAAATGTGT
CAAACTCTAAGCCATAGCTTGCAAAAACACCTTTTATTTTTAAAATTCCTTTTTAAAGAATTTGATTTTTTAGACAGCTT
GCAAGCCCGGCTTAATTTCGCTAAAGCCTACAATTTAGAATTTGTCATGCCAAGCTTTACTCAAAAAAAAATGATTTTAG
AAAACTTTTCGCACCCCATTTTAAAAGAGCCAAAGCCCTTAAATTTGAAGTTTGAAAAATCCATGCTCGCTGTTACCGGC
GTGAATGCGGGCGGGAAAACCATGCTCTTAAAATCGCTTTTAAGCGCGGCTTTTTTAAGCAAGCATCTCATTGCTATGAA
AATCAACGCCCATCATTCCATTATCCCCTATTTTAAAGAAATCCACGCCATTATTAATGACCCCCAAAACAGCGCGAACA
ATATCTCTACTTTTGCCGGCAGAATGAAGCAATTTAGCGCTCTTTTATCCAAAGAAAACATGCTTTTAGGCGTTGATGAA
ATTGAGCTGGGGACTGACGCTGATGAAGCGAGCAGTTTGTATAAAACCCTGTTAGAAAAATTGCTTAAACAAAACAACCA
AATCATTATCACCACGCACCACAAACGCCTGAGCGTGTTAATGGCAGAAAACAAGGAAGTGGAATTACTAGCCGCTCTTT
ATGATGAAGAAAAAGAACGGCCCACTTACACTTTTTTAAAAGGGGTTATTGGCAAAAGCTATGCGTTTGAAACCGCTTTG
CGCTATGGCGTGCCGCATTTTTTGATTGAAAAAGCGAAAGCTTTCTATGGCGAAGATAAGGAAAAATTGAATGTTTTGAT
TGAAAATTCCAGCGCATTAGAAAGGGAATTGAAGCAAAAAAACGAACTTTTAGAGAACGCTTTAAAAGAGCAAGAAGATT
TAAAAAACGCATGGCTTTTAGAAATGGAAAAACAAAAAGAAACCTTTCACAATAAAAAATTGGAATTGGAAAAATCCTAC
CAACAAGCCCTAAATATCTTAAAAAGCGAAGTCGCTTCAAAAGATACCAGCTCCATGCATAAAGAAATCCATAAAGCGAG
CGAAATTTTAAACAAGCATAAAACAAACCAAGAGATCCCACAAATCATAACGAGCTTTCAAGCCAACGAAAAAGCGCGCT
ATAAAAATGAAAGCGTGCTGATTGTGCAAATTTTAGACAAGGGCTATTATTGGATAGAAACCGAGCTTGGCATGCGTTTA
AAAGCGCATGGGAGTTTGTTGAAAAAAATCCAAAAACCCCCTAAAAACAAATTCAAACCCCCTAAAACAACCATTCCTAA
ACCCCAAAAGGCGAGCTTACGCCTTGATTTAAGGGGGCAACGCAGCGAAGAAGCCCTGGATTTACTAGATGCTTTTTTAA
ACGACGCGCTTTTAGGGGGCTTTGAAGAAGTGCTTATTTGCCATGGCAAGGGAAGCGGGATTTTAGAAAAGTTTGTGAAA
GAATTTTTAAAAAACCACCCTAAAGTGGTAAGCTTTAACGACGCTCCCATTAATTTAGGTGGCAGTGGGGTTAAAATCGT
TAAATTGTAG

Upstream 100 bases:

>100_bases
TTTAGGCAAAAAACAAACCCCTATGAAAGATGTTCTTGTGGATTTGGATTCTTGTCAGACGCTTCAAAAAGATCCCTTAA
TCCAACCCCAATGAATCCCA

Downstream 100 bases:

>100_bases
TTTTTGGCGCTTTTTATGGGGGATTAATATAAAAATCCGCTTTAAATTATAAAGCCATTTTACACCAACACTCAATGAGA
ACAAAGCTTTTTTAAAAGAG

Product: recombination and DNA strand exchange inhibitor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 749

Protein sequence:

>749_residues
MNNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTPKSVKESNLIIIKLTKLGTLH
LDEIHEIVKRLRYIVILQNAFKTFTHLKFHERLNAIVLPPFFNDLIALFDDEGKIKQGANATLDALNESLNRLKKESAKI
IHHYAHSKELAPYLVDTQSHLKHGYECLLLKSGFSSAIKGVVLERSANGYFYLLPESVQKIAQKIAQIDNEIDCCIVEMC
QTLSHSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMILENFSHPILKEPKPLNLKFEKSMLAVTG
VNAGGKTMLLKSLLSAAFLSKHLIAMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDE
IELGTDADEASSLYKTLLEKLLKQNNQIIITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLKGVIGKSYAFETAL
RYGVPHFLIEKAKAFYGEDKEKLNVLIENSSALERELKQKNELLENALKEQEDLKNAWLLEMEKQKETFHNKKLELEKSY
QQALNILKSEVASKDTSSMHKEIHKASEILNKHKTNQEIPQIITSFQANEKARYKNESVLIVQILDKGYYWIETELGMRL
KAHGSLLKKIQKPPKNKFKPPKTTIPKPQKASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLICHGKGSGILEKFVK
EFLKNHPKVVSFNDAPINLGGSGVKIVKL

Sequences:

>Translated_749_residues
MNNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTPKSVKESNLIIIKLTKLGTLH
LDEIHEIVKRLRYIVILQNAFKTFTHLKFHERLNAIVLPPFFNDLIALFDDEGKIKQGANATLDALNESLNRLKKESAKI
IHHYAHSKELAPYLVDTQSHLKHGYECLLLKSGFSSAIKGVVLERSANGYFYLLPESVQKIAQKIAQIDNEIDCCIVEMC
QTLSHSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMILENFSHPILKEPKPLNLKFEKSMLAVTG
VNAGGKTMLLKSLLSAAFLSKHLIAMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDE
IELGTDADEASSLYKTLLEKLLKQNNQIIITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLKGVIGKSYAFETAL
RYGVPHFLIEKAKAFYGEDKEKLNVLIENSSALERELKQKNELLENALKEQEDLKNAWLLEMEKQKETFHNKKLELEKSY
QQALNILKSEVASKDTSSMHKEIHKASEILNKHKTNQEIPQIITSFQANEKARYKNESVLIVQILDKGYYWIETELGMRL
KAHGSLLKKIQKPPKNKFKPPKTTIPKPQKASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLICHGKGSGILEKFVK
EFLKNHPKVVSFNDAPINLGGSGVKIVKL
>Mature_749_residues
MNNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTPKSVKESNLIIIKLTKLGTLH
LDEIHEIVKRLRYIVILQNAFKTFTHLKFHERLNAIVLPPFFNDLIALFDDEGKIKQGANATLDALNESLNRLKKESAKI
IHHYAHSKELAPYLVDTQSHLKHGYECLLLKSGFSSAIKGVVLERSANGYFYLLPESVQKIAQKIAQIDNEIDCCIVEMC
QTLSHSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMILENFSHPILKEPKPLNLKFEKSMLAVTG
VNAGGKTMLLKSLLSAAFLSKHLIAMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDE
IELGTDADEASSLYKTLLEKLLKQNNQIIITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLKGVIGKSYAFETAL
RYGVPHFLIEKAKAFYGEDKEKLNVLIENSSALERELKQKNELLENALKEQEDLKNAWLLEMEKQKETFHNKKLELEKSY
QQALNILKSEVASKDTSSMHKEIHKASEILNKHKTNQEIPQIITSFQANEKARYKNESVLIVQILDKGYYWIETELGMRL
KAHGSLLKKIQKPPKNKFKPPKTTIPKPQKASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLICHGKGSGILEKFVK
EFLKNHPKVVSFNDAPINLGGSGVKIVKL

Specific function: This Protein Is Involved In The Repair Of Mismatches In DNA. It Is Possible That It Carries Out The Mismatch Recognition Step. This Protein Has A Weak Atpase Activity. [C]

COG id: COG1193

COG function: function code L; Mismatch repair ATPase (MutS family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Smr domain [H]

Homologues:

Organism=Escherichia coli, GI1789089, Length=260, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005747
- InterPro:   IPR000432
- InterPro:   IPR007696
- InterPro:   IPR002625 [H]

Pfam domain/function: PF00488 MutS_V; PF01713 Smr [H]

EC number: NA

Molecular weight: Translated: 85302; Mature: 85302

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50828 SMR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTP
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCC
KSVKESNLIIIKLTKLGTLHLDEIHEIVKRLRYIVILQNAFKTFTHLKFHERLNAIVLPP
CCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
FFNDLIALFDDEGKIKQGANATLDALNESLNRLKKESAKIIHHYAHSKELAPYLVDTQSH
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHH
LKHGYECLLLKSGFSSAIKGVVLERSANGYFYLLPESVQKIAQKIAQIDNEIDCCIVEMC
HCCCCEEEEEECCHHHHHHCEEEEECCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHH
QTLSHSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMILENFSHPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCCC
LKEPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIAMKINAHHSIIPYFKE
CCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHH
IHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIELGTDADEASSLYKTLLEK
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCEECCCCHHHHHHHHHHHHHH
LLKQNNQIIITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLKGVIGKSYAFETAL
HHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHH
RYGVPHFLIEKAKAFYGEDKEKLNVLIENSSALERELKQKNELLENALKEQEDLKNAWLL
HHCCHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
EMEKQKETFHNKKLELEKSYQQALNILKSEVASKDTSSMHKEIHKASEILNKHKTNQEIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHH
QIITSFQANEKARYKNESVLIVQILDKGYYWIETELGMRLKAHGSLLKKIQKPPKNKFKP
HHHHHHCCCCHHHCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCC
PKTTIPKPQKASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLICHGKGSGILEKFVK
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
EFLKNHPKVVSFNDAPINLGGSGVKIVKL
HHHHCCCCEEEECCCCCEECCCCEEEEEC
>Mature Secondary Structure
MNNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTP
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCC
KSVKESNLIIIKLTKLGTLHLDEIHEIVKRLRYIVILQNAFKTFTHLKFHERLNAIVLPP
CCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
FFNDLIALFDDEGKIKQGANATLDALNESLNRLKKESAKIIHHYAHSKELAPYLVDTQSH
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHH
LKHGYECLLLKSGFSSAIKGVVLERSANGYFYLLPESVQKIAQKIAQIDNEIDCCIVEMC
HCCCCEEEEEECCHHHHHHCEEEEECCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHH
QTLSHSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMILENFSHPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCCC
LKEPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIAMKINAHHSIIPYFKE
CCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHH
IHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIELGTDADEASSLYKTLLEK
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCEECCCCHHHHHHHHHHHHHH
LLKQNNQIIITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLKGVIGKSYAFETAL
HHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHH
RYGVPHFLIEKAKAFYGEDKEKLNVLIENSSALERELKQKNELLENALKEQEDLKNAWLL
HHCCHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
EMEKQKETFHNKKLELEKSYQQALNILKSEVASKDTSSMHKEIHKASEILNKHKTNQEIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHH
QIITSFQANEKARYKNESVLIVQILDKGYYWIETELGMRLKAHGSLLKKIQKPPKNKFKP
HHHHHHCCCCHHHCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCC
PKTTIPKPQKASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLICHGKGSGILEKFVK
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
EFLKNHPKVVSFNDAPINLGGSGVKIVKL
HHHHCCCCEEEECCCCCEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]