Click here to switch to the map view.

The map label for this gene is norM [H]

Identifier: 188527397

GI number: 188527397

Start: 580763

End: 582016

Strand: Reverse

Name: norM [H]

Synonym: HPSH_03030

Alternate gene names: 188527397

Gene position: 582016-580763 (Counterclockwise)

Preceding gene: 188527398

Following gene: 188527394

Centisome position: 36.18

GC content: 38.92

Gene sequence:

>1254_bases
GTGCTAGTGGTCGCGCTCTCGGTTTTTTTTGTGGGCAAGATTTCGCACCATCACATTGTGGCTCTAGGGGTGGGCTTGCA
ATTTTTGATGCTTTTTTATGGCATCAATACGATTTTATACACCGGCACTAACGCCATTCTTTCTAGGCTTGTGGGAGCTA
GGGATTTTACTCAAATCAATCACGCTTTTTCAAGTATTTTTATAGGGGCGTTTGTGATTTGTTTGGGCGTGCTGTTTGTT
TCTTATTTTTTGATTGAGCCTTTTTTAAATTGGATGCGATTGCAAGATCCTTCGCGCCAATTGACGCAAGATTATTTAGA
AGTCTTAGTCATCGCGCTACCGAGTGTTTTTTTAAAAAATGTTTTAGTTTCAGCGCTCGCTAGCTTTTCAGACACCCTAA
CCCCCTTTATTGTCAAAATCATCATGGTCATCGCATGCATTTTCTTGAATCAAGCCTTGATTTTTGGGGATTTTGGTTTT
AAAGAAATGGGGATTGTAGGCTCTGCTTTAGCGAATGTGATTGTTTCTTATTTGGAATTACTCGCGCTTGGCGTTTGGAT
ACAAATCAAAAAAATCCCTTTAAAATTCAAAATAACCTTTAATTTTTCTTTTTTAAAAACCATGTTTAGAGTGGGTTGGC
CGGCCGGGTTTGAGCGCTTATTGAGCTTATTTTCTTTAATCCTCTTATCCAAATTTGTAGCGAGCTATGGGGATAAAGTG
TTAGCGGGCATGCAAATAGGTATTAGGGTTGAAACCTTTTCGTTCATGCCCGGATTTGGGTTTATGATCGCAGCGATGGT
TTTAATAGGGCAAAATTTAGGAGCGAACAAGCCAAAAATCGCCACAGAATACGCGCATTTGATTTTAAAAATTTCTATGG
GTTTAATGGGGGCTTTAGGGATTGTTTTAGTTTTATTCGCTAAAGAATTTGCGAGCCTTTTTTCTCAAGATGAAGAAGTC
TTGGAAGTGGCGCGATCTTATTTGATCGCTGTGGGTCTTTCTCAAGCCCCCTTAATTGGGTATTTTGTGCTGGATGGAGT
TTTTAGAGGGGCTGGCATTTCTAAAGTCTCACTGTATATTAACACCCTAAGCTTATGGGGGTTAAGGATCATGCCCATTT
ACTTGCTTTTAATTTATCATTTTAAGGTGGAATTTATTTTTGTAGTGATCGCATCAGAAACTTTTTTGCGCTCATTCATC
TATTATAAAGTTTTTTCTAAAGGCATTTGGAAAAGGTGCGGGAAAAAGGCTTGA

Upstream 100 bases:

>100_bases
TTGTTTTTGGAGTGGTTGGAGCGTTACTATTAGGCTAATCTATCAAGTTAAGAAAATCTTTTCTTTAGCCTTACCCTCTG
GGATTAATGCTTTTTTAGAT

Downstream 100 bases:

>100_bases
TTATTGCTTGAGTGTAGCGGTCGTTTTGAAACGGCTTTCTCGCACCACTTGCACGCCCACTTCGCCCACATACTGAGCGC
TCTCTTCTATCTTTTTAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MLVVALSVFFVGKISHHHIVALGVGLQFLMLFYGINTILYTGTNAILSRLVGARDFTQINHAFSSIFIGAFVICLGVLFV
SYFLIEPFLNWMRLQDPSRQLTQDYLEVLVIALPSVFLKNVLVSALASFSDTLTPFIVKIIMVIACIFLNQALIFGDFGF
KEMGIVGSALANVIVSYLELLALGVWIQIKKIPLKFKITFNFSFLKTMFRVGWPAGFERLLSLFSLILLSKFVASYGDKV
LAGMQIGIRVETFSFMPGFGFMIAAMVLIGQNLGANKPKIATEYAHLILKISMGLMGALGIVLVLFAKEFASLFSQDEEV
LEVARSYLIAVGLSQAPLIGYFVLDGVFRGAGISKVSLYINTLSLWGLRIMPIYLLLIYHFKVEFIFVVIASETFLRSFI
YYKVFSKGIWKRCGKKA

Sequences:

>Translated_417_residues
MLVVALSVFFVGKISHHHIVALGVGLQFLMLFYGINTILYTGTNAILSRLVGARDFTQINHAFSSIFIGAFVICLGVLFV
SYFLIEPFLNWMRLQDPSRQLTQDYLEVLVIALPSVFLKNVLVSALASFSDTLTPFIVKIIMVIACIFLNQALIFGDFGF
KEMGIVGSALANVIVSYLELLALGVWIQIKKIPLKFKITFNFSFLKTMFRVGWPAGFERLLSLFSLILLSKFVASYGDKV
LAGMQIGIRVETFSFMPGFGFMIAAMVLIGQNLGANKPKIATEYAHLILKISMGLMGALGIVLVLFAKEFASLFSQDEEV
LEVARSYLIAVGLSQAPLIGYFVLDGVFRGAGISKVSLYINTLSLWGLRIMPIYLLLIYHFKVEFIFVVIASETFLRSFI
YYKVFSKGIWKRCGKKA
>Mature_417_residues
MLVVALSVFFVGKISHHHIVALGVGLQFLMLFYGINTILYTGTNAILSRLVGARDFTQINHAFSSIFIGAFVICLGVLFV
SYFLIEPFLNWMRLQDPSRQLTQDYLEVLVIALPSVFLKNVLVSALASFSDTLTPFIVKIIMVIACIFLNQALIFGDFGF
KEMGIVGSALANVIVSYLELLALGVWIQIKKIPLKFKITFNFSFLKTMFRVGWPAGFERLLSLFSLILLSKFVASYGDKV
LAGMQIGIRVETFSFMPGFGFMIAAMVLIGQNLGANKPKIATEYAHLILKISMGLMGALGIVLVLFAKEFASLFSQDEEV
LEVARSYLIAVGLSQAPLIGYFVLDGVFRGAGISKVSLYINTLSLWGLRIMPIYLLLIYHFKVEFIFVVIASETFLRSFI
YYKVFSKGIWKRCGKKA

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=439, Percent_Identity=23.6902050113895, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 46471; Mature: 46471

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVVALSVFFVGKISHHHIVALGVGLQFLMLFYGINTILYTGTNAILSRLVGARDFTQIN
CCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHH
HAFSSIFIGAFVICLGVLFVSYFLIEPFLNWMRLQDPSRQLTQDYLEVLVIALPSVFLKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLVSALASFSDTLTPFIVKIIMVIACIFLNQALIFGDFGFKEMGIVGSALANVIVSYLEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHH
LALGVWIQIKKIPLKFKITFNFSFLKTMFRVGWPAGFERLLSLFSLILLSKFVASYGDKV
HHHHHHHEEEECCEEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
LAGMQIGIRVETFSFMPGFGFMIAAMVLIGQNLGANKPKIATEYAHLILKISMGLMGALG
HHCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IVLVLFAKEFASLFSQDEEVLEVARSYLIAVGLSQAPLIGYFVLDGVFRGAGISKVSLYI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
NTLSLWGLRIMPIYLLLIYHFKVEFIFVVIASETFLRSFIYYKVFSKGIWKRCGKKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLVVALSVFFVGKISHHHIVALGVGLQFLMLFYGINTILYTGTNAILSRLVGARDFTQIN
CCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHH
HAFSSIFIGAFVICLGVLFVSYFLIEPFLNWMRLQDPSRQLTQDYLEVLVIALPSVFLKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLVSALASFSDTLTPFIVKIIMVIACIFLNQALIFGDFGFKEMGIVGSALANVIVSYLEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHH
LALGVWIQIKKIPLKFKITFNFSFLKTMFRVGWPAGFERLLSLFSLILLSKFVASYGDKV
HHHHHHHEEEECCEEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
LAGMQIGIRVETFSFMPGFGFMIAAMVLIGQNLGANKPKIATEYAHLILKISMGLMGALG
HHCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IVLVLFAKEFASLFSQDEEVLEVARSYLIAVGLSQAPLIGYFVLDGVFRGAGISKVSLYI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
NTLSLWGLRIMPIYLLLIYHFKVEFIFVVIASETFLRSFIYYKVFSKGIWKRCGKKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]