| Definition | Helicobacter pylori Shi470, complete genome. |
|---|---|
| Accession | NC_010698 |
| Length | 1,608,548 |
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The map label for this gene is acnB [H]
Identifier: 188527376
GI number: 188527376
Start: 560042
End: 562600
Strand: Reverse
Name: acnB [H]
Synonym: HPSH_02915
Alternate gene names: 188527376
Gene position: 562600-560042 (Counterclockwise)
Preceding gene: 188527385
Following gene: 188527375
Centisome position: 34.98
GC content: 44.82
Gene sequence:
>2559_bases ATGAAAGATTTTTTAGAAGATTATAAAAAAAGCGTTTTAGAAAGAGAAAGCGATGGTATCCCGCCGCTCCCTTTAAACGC TAAACAAGTAGAAGCCGTCGTTGAGATTTTGATGAAAGATCCCACAAATGCCGCTTTCGCTAAAGAATTACTCATTCACA GAGTGAGCCCTGGGGTTGATGAGGGGGCGAAAGTGAAAGCGGAATTTTTAGCCAAATTGTCTCAAAAAAAACTAGAATGC GCGTGCATTAGCGCTTTAGAAGCGACCACTCTTTTAGGCACGATGCTTGGGGGGTATAATGTAGAGCCTTTGATTATGGG CTTAGAAAGTCAAGACAAAAACATCGCCAAAGAGAGCGCGAAAGCTTTAAAAACCACTCTTTTAGTCTATGGATCGTTTG ATAAAATCGCTACAATGAGTAAAACTAACGCTCTGGCTAAAGAGGTGCTAGAGTCTTGGGCGAACGCTGAATGGTTTTTG AATAAAGAGCCTTTGAATGAATGCATTGAAGCGTGCGTGTTTAAGATTGATGGCGAAACCAATACCGATGATTTAAGCCC AGCGAGCGATGCTTTCACACGAAGCGATATTCCTTTACACGCCAAAGCGATGCTCAAAAACAGGATTGAAAATTACGAAC AACGCATCAAAGCCATTAAAGCTAAAGGCGTTCCTGTAGCGTATGTGGGCGATGTGGTCGGCACAGGAAGCTCTAGAAAA AGCGCAACAAACTCTATCATGTGGCATTTTGGTAAGGACATTCCTTTTGTGCCTAATAAAAGGAGTGGAGGTATTGTGAT TGGGGGGGTGATCGCTCCGATTTTCTTTGCAACTTGTGAAGATAGTGGGGCGTTACCTATTGTGGCTGATGTTAAGGATT TAAAAGAGGGCGATATGATTAAAATCTATCCTTATAAAGGCGAAATCACGCTGAATGATAAAGTGGTCAGCACCTTTAAA CTAGAACCTGAAACTTTATTAGATGAAGTTAGGGCTTCTGGGCGTATCCCTTTAATCATTGGTAGAGGTTTGACGAATAA AGCGCGTAAATTTTTGGGGCTGGGCGAATCTGAAGCGTTTAAAAAGCCATCCGCTCCTAAAAGCGACGCCAAAGGTTACA CTTTAGCCCAAAAAATTGTAGGCCATGCTTGTGGGGTAAAAGGGATCTTACCTGGCACTTATTGTGAGCCAAAGGTTACC ACTGTGGGCAGTCAAGACACCACAGGGGCGATGACTAGAGATGAGGTTAAAGAATTAGCGAGTTTGAAATTTGATGCACC TTTTGTGTTGCAGAGTTTTTGCCATACCGCCGCTTACCCAAAGCCTAGCGATGTGAGTTTGCATGCAACCTTGCCTAGCT TTATCACTCAAAGAGGCGGTGTGGCGTTGCATCCGGGCGATGGCGTGATCCATACATGGCTAAACCGCATGGGATTGCCT GACACTTTAGGCACAGGGGGGGATAGCCACACTCGTTTCCCTTTAGGCATTAGTTTCCCGGCAGGGAGCGGGTTAGTCGC TTTTGCAGCGGTTACAGGCACGATGCCCTTGAACATGCCAGAATCCGTGTTGGTGCGTTTTAAAGGGGAAATGAATCCTG GGATCACCTTAAGGGATTTAGTGAATGCGATCCCTTATTATGCCATTAAAAAAGGGTTACTCACCGTGGAGAAAAAGGGT AAAATCAATGTCTTTAATGGGCGTATTTTAGAGATTGAAGGCTTGCCTGATATTAAAATGGAGCAGGCTTTTGAACTAAG CGATGCGAGCGCAGAAAGGAGCGCGGCTGCTTGCGTGGTGCGTTTGAATAAAGAGCCAATGATTGAATACTTGAAATCCA ATATCAAGCTTATTGATGAGATGATTGCGAGCGGCTATGAAGACAAAGAGACTTTGAAAAAACGCCGAGATGCGATGCAA GCTTGGGTGGATAATCCGGTATTGTTAGAGCCAGATAGTAACGCTCAATACGCCGCTGTCATTGAAATTGATGTGGCAGA AATCACTGAGCCTATTTTGGCGTGCCCTAATGACCCTGATGATGTCGCTACTTTGAGCGAAGTTTTAGCGGATACGACCG GCAAAAGACCGCACGCTATTGATGAAGTGTTTATTGGCTCTTGCATGACGAATATCGGGCATTTTAGAGCCTTTGGCGAA ATCGTTAAAAACGCTCCCCCCAGTCAGGCGCGTCTTTGGGTAGTGCCACCCAGTAAAATGGATGAACAAGAGCTTATTAA TGAGGGCTATTATGCGATTTTTGGGGCTGCCGGGGCAAGGACTGAAGTCCCAGGCTGTAGCTTGTGTATGGGCAATCAGG CGAGGGTTAGGGATAATGCGGTCGTCTTTTCTACTTCCACACGGAATTTTGATAATCGTATGGGTAGAGGGGCTAAAGTG TATTTAGGCAGTGCAGAGCTTGGGGCGGCGTGCGCTTTACTAGGGAGAATCCCCACTAAAGAAGAATACATGAATTTAGT GAGTGAAAAGCTAGAGAGCCAAAAAGACAAGATCTATCGCTACATGAACTTTAACTTAATGGAGAATTTCAGGCTCTAG
Upstream 100 bases:
>100_bases TAAAGTTTCTTACAACTTAACTAAAAGTAAAAAGAGTTTTGTTATCATGGGGCAAATGATTAGGGCATTAGTCAATAATG CTATTTAAAAAGGAGAAATG
Downstream 100 bases:
>100_bases TTTTGCATTAAAAGGGGCGATCCCTTTTATTTAGCTGTGGCTGAGTGTTGGAATAGGATAAAAAAGGAGAGCGGTGGTGA AAAAAATCGTTGTGAGTTGG
Product: bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
Products: NA
Alternate protein names: Aconitase 2; 2-methylisocitrate dehydratase; Citrate hydro-lyase 2 [H]
Number of amino acids: Translated: 852; Mature: 852
Protein sequence:
>852_residues MKDFLEDYKKSVLERESDGIPPLPLNAKQVEAVVEILMKDPTNAAFAKELLIHRVSPGVDEGAKVKAEFLAKLSQKKLEC ACISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKESAKALKTTLLVYGSFDKIATMSKTNALAKEVLESWANAEWFL NKEPLNECIEACVFKIDGETNTDDLSPASDAFTRSDIPLHAKAMLKNRIENYEQRIKAIKAKGVPVAYVGDVVGTGSSRK SATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVKDLKEGDMIKIYPYKGEITLNDKVVSTFK LEPETLLDEVRASGRIPLIIGRGLTNKARKFLGLGESEAFKKPSAPKSDAKGYTLAQKIVGHACGVKGILPGTYCEPKVT TVGSQDTTGAMTRDEVKELASLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPSFITQRGGVALHPGDGVIHTWLNRMGLP DTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLVRFKGEMNPGITLRDLVNAIPYYAIKKGLLTVEKKG KINVFNGRILEIEGLPDIKMEQAFELSDASAERSAAACVVRLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAMQ AWVDNPVLLEPDSNAQYAAVIEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDEVFIGSCMTNIGHFRAFGE IVKNAPPSQARLWVVPPSKMDEQELINEGYYAIFGAAGARTEVPGCSLCMGNQARVRDNAVVFSTSTRNFDNRMGRGAKV YLGSAELGAACALLGRIPTKEEYMNLVSEKLESQKDKIYRYMNFNLMENFRL
Sequences:
>Translated_852_residues MKDFLEDYKKSVLERESDGIPPLPLNAKQVEAVVEILMKDPTNAAFAKELLIHRVSPGVDEGAKVKAEFLAKLSQKKLEC ACISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKESAKALKTTLLVYGSFDKIATMSKTNALAKEVLESWANAEWFL NKEPLNECIEACVFKIDGETNTDDLSPASDAFTRSDIPLHAKAMLKNRIENYEQRIKAIKAKGVPVAYVGDVVGTGSSRK SATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVKDLKEGDMIKIYPYKGEITLNDKVVSTFK LEPETLLDEVRASGRIPLIIGRGLTNKARKFLGLGESEAFKKPSAPKSDAKGYTLAQKIVGHACGVKGILPGTYCEPKVT TVGSQDTTGAMTRDEVKELASLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPSFITQRGGVALHPGDGVIHTWLNRMGLP DTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLVRFKGEMNPGITLRDLVNAIPYYAIKKGLLTVEKKG KINVFNGRILEIEGLPDIKMEQAFELSDASAERSAAACVVRLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAMQ AWVDNPVLLEPDSNAQYAAVIEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDEVFIGSCMTNIGHFRAFGE IVKNAPPSQARLWVVPPSKMDEQELINEGYYAIFGAAGARTEVPGCSLCMGNQARVRDNAVVFSTSTRNFDNRMGRGAKV YLGSAELGAACALLGRIPTKEEYMNLVSEKLESQKDKIYRYMNFNLMENFRL >Mature_852_residues MKDFLEDYKKSVLERESDGIPPLPLNAKQVEAVVEILMKDPTNAAFAKELLIHRVSPGVDEGAKVKAEFLAKLSQKKLEC ACISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKESAKALKTTLLVYGSFDKIATMSKTNALAKEVLESWANAEWFL NKEPLNECIEACVFKIDGETNTDDLSPASDAFTRSDIPLHAKAMLKNRIENYEQRIKAIKAKGVPVAYVGDVVGTGSSRK SATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVKDLKEGDMIKIYPYKGEITLNDKVVSTFK LEPETLLDEVRASGRIPLIIGRGLTNKARKFLGLGESEAFKKPSAPKSDAKGYTLAQKIVGHACGVKGILPGTYCEPKVT TVGSQDTTGAMTRDEVKELASLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPSFITQRGGVALHPGDGVIHTWLNRMGLP DTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLVRFKGEMNPGITLRDLVNAIPYYAIKKGLLTVEKKG KINVFNGRILEIEGLPDIKMEQAFELSDASAERSAAACVVRLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAMQ AWVDNPVLLEPDSNAQYAAVIEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDEVFIGSCMTNIGHFRAFGE IVKNAPPSQARLWVVPPSKMDEQELINEGYYAIFGAAGARTEVPGCSLCMGNQARVRDNAVVFSTSTRNFDNRMGRGAKV YLGSAELGAACALLGRIPTKEEYMNLVSEKLESQKDKIYRYMNFNLMENFRL
Specific function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate as well as the dehydration of 2-methylisocitrate to cis-2-methylaconitate [H]
COG id: COG1049
COG function: function code C; Aconitase B
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aconitase/IPM isomerase family [H]
Homologues:
Organism=Escherichia coli, GI2367097, Length=864, Percent_Identity=60.7638888888889, Blast_Score=1018, Evalue=0.0, Organism=Escherichia coli, GI1786259, Length=377, Percent_Identity=28.3819628647215, Blast_Score=96, Evalue=1e-20, Organism=Saccharomyces cerevisiae, GI6321429, Length=371, Percent_Identity=26.6846361185984, Blast_Score=69, Evalue=4e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015931 - InterPro: IPR015937 - InterPro: IPR001030 - InterPro: IPR015928 - InterPro: IPR015932 - InterPro: IPR018136 - InterPro: IPR004406 - InterPro: IPR015930 - InterPro: IPR015933 - InterPro: IPR015929 [H]
Pfam domain/function: PF00330 Aconitase; PF06434 Aconitase_2_N; PF11791 Aconitase_B_N [H]
EC number: =4.2.1.3; =4.2.1.99 [H]
Molecular weight: Translated: 92765; Mature: 92765
Theoretical pI: Translated: 6.20; Mature: 6.20
Prosite motif: PS00450 ACONITASE_1 ; PS01244 ACONITASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKDFLEDYKKSVLERESDGIPPLPLNAKQVEAVVEILMKDPTNAAFAKELLIHRVSPGVD CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC EGAKVKAEFLAKLSQKKLECACISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKESA CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHH KALKTTLLVYGSFDKIATMSKTNALAKEVLESWANAEWFLNKEPLNECIEACVFKIDGET HHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHEEEECCCC NTDDLSPASDAFTRSDIPLHAKAMLKNRIENYEQRIKAIKAKGVPVAYVGDVVGTGSSRK CCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHCCCCCCC SATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVKDLKEGDMI HHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEECHHHCCCCCEE KIYPYKGEITLNDKVVSTFKLEPETLLDEVRASGRIPLIIGRGLTNKARKFLGLGESEAF EEEEECCEEEECCCEEEEEECCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCHHHC KKPSAPKSDAKGYTLAQKIVGHACGVKGILPGTYCEPKVTTVGSQDTTGAMTRDEVKELA CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHH SLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPSFITQRGGVALHPGDGVIHTWLNRMGLP HCCCCCHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHCCCEEECCCCCHHHHHHHHCCCC DTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLVRFKGEMNPGITLRDL CCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHEEECCCCCCCEEHHHH VNAIPYYAIKKGLLTVEKKGKINVFNGRILEIEGLPDIKMEQAFELSDASAERSAAACVV HHHHHHHHHHHCCEEEECCCEEEEECCEEEEECCCCCCCHHHHHCCCCCCHHHHHEEEEE RLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAMQAWVDNPVLLEPDSNAQYAAV EECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEE IEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDEVFIGSCMTNIGHFRAFGE EEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH IVKNAPPSQARLWVVPPSKMDEQELINEGYYAIFGAAGARTEVPGCSLCMGNQARVRDNA HHHCCCCCCCEEEEECCCCCCHHHHHHCCCEEEEECCCCCCCCCCCEEECCCCCEECCCE VVFSTSTRNFDNRMGRGAKVYLGSAELGAACALLGRIPTKEEYMNLVSEKLESQKDKIYR EEEEECCCCHHHHCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH YMNFNLMENFRL HHCCCHHHHCCC >Mature Secondary Structure MKDFLEDYKKSVLERESDGIPPLPLNAKQVEAVVEILMKDPTNAAFAKELLIHRVSPGVD CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC EGAKVKAEFLAKLSQKKLECACISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKESA CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHH KALKTTLLVYGSFDKIATMSKTNALAKEVLESWANAEWFLNKEPLNECIEACVFKIDGET HHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHEEEECCCC NTDDLSPASDAFTRSDIPLHAKAMLKNRIENYEQRIKAIKAKGVPVAYVGDVVGTGSSRK CCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHCCCCCCC SATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVKDLKEGDMI HHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEECHHHCCCCCEE KIYPYKGEITLNDKVVSTFKLEPETLLDEVRASGRIPLIIGRGLTNKARKFLGLGESEAF EEEEECCEEEECCCEEEEEECCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCHHHC KKPSAPKSDAKGYTLAQKIVGHACGVKGILPGTYCEPKVTTVGSQDTTGAMTRDEVKELA CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHH SLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPSFITQRGGVALHPGDGVIHTWLNRMGLP HCCCCCHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHCCCEEECCCCCHHHHHHHHCCCC DTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLVRFKGEMNPGITLRDL CCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHEEECCCCCCCEEHHHH VNAIPYYAIKKGLLTVEKKGKINVFNGRILEIEGLPDIKMEQAFELSDASAERSAAACVV HHHHHHHHHHHCCEEEECCCEEEEECCEEEEECCCCCCCHHHHHCCCCCCHHHHHEEEEE RLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAMQAWVDNPVLLEPDSNAQYAAV EECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEE IEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDEVFIGSCMTNIGHFRAFGE EEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH IVKNAPPSQARLWVVPPSKMDEQELINEGYYAIFGAAGARTEVPGCSLCMGNQARVRDNA HHHCCCCCCCEEEEECCCCCCHHHHHHCCCEEEEECCCCCCCCCCCEEECCCCCEECCCE VVFSTSTRNFDNRMGRGAKVYLGSAELGAACALLGRIPTKEEYMNLVSEKLESQKDKIYR EEEEECCCCHHHHCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH YMNFNLMENFRL HHCCCHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9923682 [H]