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The map label for this gene is engA

Identifier: 188527319

GI number: 188527319

Start: 509662

End: 511047

Strand: Reverse

Name: engA

Synonym: HPSH_02630

Alternate gene names: 188527319

Gene position: 511047-509662 (Counterclockwise)

Preceding gene: 188527326

Following gene: 188527318

Centisome position: 31.77

GC content: 39.54

Gene sequence:

>1386_bases
ATGAATACAAGCCATAAAACTTTAAAAACCATTGCGATTTTAGGCCAGCCTAATGTGGGGAAAAGCTCGTTATTTAACCG
CTTAGCTAGAGAAAGGATCGCTATCACTTCAGATTTTGCAGGCACTACACGAGACATTAACAAACGAAAAATCGCATTGA
ATGGCCATGAAGTGGAATTGCTAGATACAGGGGGCATGGCTAAAGACGCTCTTTTGTCTAAAGAAATCAAAGCCCTTAAT
TTAAAAGCCGCTCAAATGAGCGATTTGATTTTATATGTTGTGGATGGCAAGTCTATCCCTAGCGATGAAGATCTCAAGCT
TTTTAGAGAGGTTTTTAAAACCAACCCTAACTGCTTTTTAGTGATCAATAAAATTGATAACGACAAAGAAAAAGAGCGAG
CTTATGCGTTTTCTTCTTTTGGCATGCCAAAGAGTTTTAATATTTCTGTTTCGCACAATAGAGGCATTAGCACCTTAATT
GATGCGATATTGAGCGCACTGGATTTGAATCAAATCATAGAGCAGGATTTGGATGCGGATATTTTAGAAAGCCTAGAAAA
TAACGCACCAAAAGAAGAAATTAAAGAAGAAGAGATCATTCAAGTAGGCATCATTGGGAGGGTGAATGTGGGCAAAAGCT
CGCTCTTAAACGCGCTCACGAAAAAAGAAAGGAGCCTTGTTTCTAGCGTGGCTGGCACTACCATTGATCCCATAGATGAA
ACCATTCTAATAGGCGATCAAAAAATTTGCTTTGTGGATACCGCTGGCATCAGGCATAGGGGTAAGATTTTAGGCATTGA
AAAATACGCGCTAGAACGCACGCAAAAAGCCTTAGAAAAATCCCACATCGCGCTTTTAGTTTTAGATGTGAGCGCTCCTT
TTGTGGAATTAGACGAAAAGATCAGCTCCTTAGCGGACAAACACTCTTTAGGCATCATTCTTATTTTAAACAAATGGGAC
ATCCGCTACGCCCCTTATGAAGAAATCATGGCAACTTTAAAAAGGAAATTCCGCTTTTTAGAATACGCCCCAATTATCAC
AACCAGCTGCTTAAAAACGCACCATATAGATGAAATCAAGCATAAAATCATAGAAGTCTATGAGTGTTTTTCCAAACGCA
TTCCCACGAGCTTGCTCAATAGCGTGATCAATCAAGCCACCCAAAAACACCCCTTGCCAAGCGATGGAGGGAAATTAGTG
AAAGTGTATTACGCCACGCAATTTGCCACCAAACCCCCTCAAATCTCTCTTATAATGAATCGCCCTAAAGCCTTGCATTT
CAGTTACAAACGCTATTTGATCAACACCTTAAGGAAAGAATTTAATTTTTTAGGCACGCCTTTAATCCTTAACGCTAAAG
ATAAAAAAAGCGCCCAACAAAATTAA

Upstream 100 bases:

>100_bases
GCCTATTTTTTTGACTAAAAACAACGCTAGACCCTTATTTAAGCTTTAAATAACTATAATATTGTAATCTAATTTTGATT
AAAGTGAAACTATAAGTAAA

Downstream 100 bases:

>100_bases
ATTTTTTATGCATTAAACCCCCTTAAAAAAGCGTTTTTGCTTGATTTATCTTTAGGATTTGATTATAATTACCGCTCAAT
CAATCAAGCTAAGCGATCAA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MNTSHKTLKTIAILGQPNVGKSSLFNRLARERIAITSDFAGTTRDINKRKIALNGHEVELLDTGGMAKDALLSKEIKALN
LKAAQMSDLILYVVDGKSIPSDEDLKLFREVFKTNPNCFLVINKIDNDKEKERAYAFSSFGMPKSFNISVSHNRGISTLI
DAILSALDLNQIIEQDLDADILESLENNAPKEEIKEEEIIQVGIIGRVNVGKSSLLNALTKKERSLVSSVAGTTIDPIDE
TILIGDQKICFVDTAGIRHRGKILGIEKYALERTQKALEKSHIALLVLDVSAPFVELDEKISSLADKHSLGIILILNKWD
IRYAPYEEIMATLKRKFRFLEYAPIITTSCLKTHHIDEIKHKIIEVYECFSKRIPTSLLNSVINQATQKHPLPSDGGKLV
KVYYATQFATKPPQISLIMNRPKALHFSYKRYLINTLRKEFNFLGTPLILNAKDKKSAQQN

Sequences:

>Translated_461_residues
MNTSHKTLKTIAILGQPNVGKSSLFNRLARERIAITSDFAGTTRDINKRKIALNGHEVELLDTGGMAKDALLSKEIKALN
LKAAQMSDLILYVVDGKSIPSDEDLKLFREVFKTNPNCFLVINKIDNDKEKERAYAFSSFGMPKSFNISVSHNRGISTLI
DAILSALDLNQIIEQDLDADILESLENNAPKEEIKEEEIIQVGIIGRVNVGKSSLLNALTKKERSLVSSVAGTTIDPIDE
TILIGDQKICFVDTAGIRHRGKILGIEKYALERTQKALEKSHIALLVLDVSAPFVELDEKISSLADKHSLGIILILNKWD
IRYAPYEEIMATLKRKFRFLEYAPIITTSCLKTHHIDEIKHKIIEVYECFSKRIPTSLLNSVINQATQKHPLPSDGGKLV
KVYYATQFATKPPQISLIMNRPKALHFSYKRYLINTLRKEFNFLGTPLILNAKDKKSAQQN
>Mature_461_residues
MNTSHKTLKTIAILGQPNVGKSSLFNRLARERIAITSDFAGTTRDINKRKIALNGHEVELLDTGGMAKDALLSKEIKALN
LKAAQMSDLILYVVDGKSIPSDEDLKLFREVFKTNPNCFLVINKIDNDKEKERAYAFSSFGMPKSFNISVSHNRGISTLI
DAILSALDLNQIIEQDLDADILESLENNAPKEEIKEEEIIQVGIIGRVNVGKSSLLNALTKKERSLVSSVAGTTIDPIDE
TILIGDQKICFVDTAGIRHRGKILGIEKYALERTQKALEKSHIALLVLDVSAPFVELDEKISSLADKHSLGIILILNKWD
IRYAPYEEIMATLKRKFRFLEYAPIITTSCLKTHHIDEIKHKIIEVYECFSKRIPTSLLNSVINQATQKHPLPSDGGKLV
KVYYATQFATKPPQISLIMNRPKALHFSYKRYLINTLRKEFNFLGTPLILNAKDKKSAQQN

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=468, Percent_Identity=30.7692307692308, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI2367268, Length=158, Percent_Identity=35.4430379746835, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=270, Percent_Identity=28.8888888888889, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51710; Mature: 51710

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSHKTLKTIAILGQPNVGKSSLFNRLARERIAITSDFAGTTRDINKRKIALNGHEVEL
CCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEECCCEEEE
LDTGGMAKDALLSKEIKALNLKAAQMSDLILYVVDGKSIPSDEDLKLFREVFKTNPNCFL
EECCCCHHHHHHHHHHHHHCCCHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEE
VINKIDNDKEKERAYAFSSFGMPKSFNISVSHNRGISTLIDAILSALDLNQIIEQDLDAD
EEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHH
ILESLENNAPKEEIKEEEIIQVGIIGRVNVGKSSLLNALTKKERSLVSSVAGTTIDPIDE
HHHHHHCCCCHHHHCHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TILIGDQKICFVDTAGIRHRGKILGIEKYALERTQKALEKSHIALLVLDVSAPFVELDEK
EEEECCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHH
ISSLADKHSLGIILILNKWDIRYAPYEEIMATLKRKFRFLEYAPIITTSCLKTHHIDEIK
HHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKIIEVYECFSKRIPTSLLNSVINQATQKHPLPSDGGKLVKVYYATQFATKPPQISLIMN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEC
RPKALHFSYKRYLINTLRKEFNFLGTPLILNAKDKKSAQQN
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MNTSHKTLKTIAILGQPNVGKSSLFNRLARERIAITSDFAGTTRDINKRKIALNGHEVEL
CCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEECCCEEEE
LDTGGMAKDALLSKEIKALNLKAAQMSDLILYVVDGKSIPSDEDLKLFREVFKTNPNCFL
EECCCCHHHHHHHHHHHHHCCCHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEE
VINKIDNDKEKERAYAFSSFGMPKSFNISVSHNRGISTLIDAILSALDLNQIIEQDLDAD
EEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHH
ILESLENNAPKEEIKEEEIIQVGIIGRVNVGKSSLLNALTKKERSLVSSVAGTTIDPIDE
HHHHHHCCCCHHHHCHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TILIGDQKICFVDTAGIRHRGKILGIEKYALERTQKALEKSHIALLVLDVSAPFVELDEK
EEEECCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHH
ISSLADKHSLGIILILNKWDIRYAPYEEIMATLKRKFRFLEYAPIITTSCLKTHHIDEIK
HHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKIIEVYECFSKRIPTSLLNSVINQATQKHPLPSDGGKLVKVYYATQFATKPPQISLIMN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEC
RPKALHFSYKRYLINTLRKEFNFLGTPLILNAKDKKSAQQN
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA