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The map label for this gene is mnmG [H]

Identifier: 188527017

GI number: 188527017

Start: 205212

End: 207077

Strand: Reverse

Name: mnmG [H]

Synonym: HPSH_01100

Alternate gene names: 188527017

Gene position: 207077-205212 (Counterclockwise)

Preceding gene: 188527023

Following gene: 188527016

Centisome position: 12.87

GC content: 41.85

Gene sequence:

>1866_bases
GTGGTAAAAGAAAGTGATATTTTAGTGATTGGTGGGGGGCATGCAGGCATTGAAGCGAGCTTGATTGCAGCCAAAATGGG
GGCTAGAGTGCATCTAATCACCATGCTCATAGACACGATCGGTTTGGCGAGCTGTAACCCGGCGATTGGAGGCTTGGGTA
AAGGGCATTTGACTAAAGAAGTGGATGTTTTAGGGGGGGCTATGGGGATTATTACGGATAATAGCGGTTTGCAATATCGT
GTGTTAAACGCTTCTAAAGGGCCGGCAGTTAGAGGGACTAGAGCGCAAATTGATATGGATACTTACCGCATTTTTGCAAG
GAATCTTGTTTTAAACACCCCTAATTTGAGCGTTTCTCAAGAAATGACTGAAAGTTTAATCATTGAAAATGATGAGATGG
TGGGCGTAACCACGAACATTAACAACACTTATAAGGCTAAAAAAGTGATCATCACCACAGGCACTTTTTTAAAAGGGGTG
GTGCATATTGGCGAGCACCAAAACCAAAACGGGCGCTTTGGGGAAAACGCTTCTAATTCTTTAGCCTTGAATTTAAGGGA
GCTTGGCTTTAGGGTGGAAAGGTTAAAAACCGGTACTTGCCCAAGAGTGGCAGGCAATAGCATTGATTTTGAAGGATTAG
AAGAGCATTTTGGGGACACAAACCCTCCCTATTTTAGCTATAAAACCAAAGATTTTAACCCCACCCAACTCTCATGTTTT
ATCACTTACACCAACCCTATTACCCACCAAATCATTAGGGATAATTTCCACCGAGCCCCCCTATTTAGCGGTCAAATTGA
AGGCATAGGCCCAAGGTATTGCCCTAGCATTGAAGATAAGATCAATCGCTTCAGCGAAAAAGAACGCCACCAGCTGTTTT
TAGAGCCTCAAACCATCCACAAAAGCGAATATTATATCAACGGCTTAAGCACCTCTTTACCCCTAGATGTGCAAGAAAAG
GTCATTCACTCTATCAAAGGCTTAGAAAACGCTCTCATCACGCGCTATGGCTATGCGATAGAGTATGATTTTATCCAGCC
CACGGAATTGACCCACACTTTAGAAACCAAAAAAATCAAGGGGCTTTATTTGGCCGGGCAAATCAATGGGACTACCGGCT
ATGAAGAAGCGGCGGCTCAAGGGCTTATGGCTGGGATTAATGCGGTATTAGCCTTAAAGAATCAAGACCCCTTTATTTTA
AAGCGCAATGAAGCTTATATCGGCGTTTTGATTGATGATTTGGTGACTAAAGGCACGAATGAGCCTTACAGAATGTTTAC
CAGCCGAGCCGAATACCGCTTGCTTTTAAGAGAGGACAACACGCTTTTTAGATTAGGCGAACATGCCTATCGTTTAGGGC
TTATGGAAGAGGATTTTTATAAGGGATTGAAAAAAGACCAACAAGAGATACAAGACAATCTCAAACGCCTTAAAGAATGC
GTCCTTACCCCCAGTAAAGAAGTGTTAAAACGCTTGAATGAATTAGACGAAAACCCTATCAATGACAAGGTTGATGGCGT
TAGCCTTTTAGCGCGCGATAGTTTTAATCTAGAAAAAATGCGCTCCTTTTTCAGCTTTTTAACGCCTTTGAATGAGCGGG
TTTTAGAGCAGATTAAAATTGAATGCAAGTATAATATTTATATTGAAAAGCAACACGAAAATATCGCTAAAATGGATAGC
ATGCTCAAAGTTTCTATCCCTAAAGGTTTTGTGTTTAAAGGCATTCCAGGCTTAAGCTTAGAAGCGGTAGAAAAGTTAGA
AAAATTCCGCCCCAAAAGCCTTTTTGAAGCCTCAGAAATCAGCGGGATCACCCCGGCGAATTTAGATGTTTTGCATTTAT
ACATCCATTTGCGAAAAAACTCTTAA

Upstream 100 bases:

>100_bases
TCCATTTTATTTTACCCTTTAAAATTACTAACCTCCATGCTACAATAAAACTTTTTCAAAACTAAGATTTTAGAAAAATC
ATATCAAAACAGGAAAAGAA

Downstream 100 bases:

>100_bases
AGGATTTTTAATGGACGCTTTAGAAATCACCCAAAAGCTCATCAGCTACCCCACCATTACGCCCAAAGAATGCGGTATTT
TTGAATACATTAAATCGCTT

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MVKESDILVIGGGHAGIEASLIAAKMGARVHLITMLIDTIGLASCNPAIGGLGKGHLTKEVDVLGGAMGIITDNSGLQYR
VLNASKGPAVRGTRAQIDMDTYRIFARNLVLNTPNLSVSQEMTESLIIENDEMVGVTTNINNTYKAKKVIITTGTFLKGV
VHIGEHQNQNGRFGENASNSLALNLRELGFRVERLKTGTCPRVAGNSIDFEGLEEHFGDTNPPYFSYKTKDFNPTQLSCF
ITYTNPITHQIIRDNFHRAPLFSGQIEGIGPRYCPSIEDKINRFSEKERHQLFLEPQTIHKSEYYINGLSTSLPLDVQEK
VIHSIKGLENALITRYGYAIEYDFIQPTELTHTLETKKIKGLYLAGQINGTTGYEEAAAQGLMAGINAVLALKNQDPFIL
KRNEAYIGVLIDDLVTKGTNEPYRMFTSRAEYRLLLREDNTLFRLGEHAYRLGLMEEDFYKGLKKDQQEIQDNLKRLKEC
VLTPSKEVLKRLNELDENPINDKVDGVSLLARDSFNLEKMRSFFSFLTPLNERVLEQIKIECKYNIYIEKQHENIAKMDS
MLKVSIPKGFVFKGIPGLSLEAVEKLEKFRPKSLFEASEISGITPANLDVLHLYIHLRKNS

Sequences:

>Translated_621_residues
MVKESDILVIGGGHAGIEASLIAAKMGARVHLITMLIDTIGLASCNPAIGGLGKGHLTKEVDVLGGAMGIITDNSGLQYR
VLNASKGPAVRGTRAQIDMDTYRIFARNLVLNTPNLSVSQEMTESLIIENDEMVGVTTNINNTYKAKKVIITTGTFLKGV
VHIGEHQNQNGRFGENASNSLALNLRELGFRVERLKTGTCPRVAGNSIDFEGLEEHFGDTNPPYFSYKTKDFNPTQLSCF
ITYTNPITHQIIRDNFHRAPLFSGQIEGIGPRYCPSIEDKINRFSEKERHQLFLEPQTIHKSEYYINGLSTSLPLDVQEK
VIHSIKGLENALITRYGYAIEYDFIQPTELTHTLETKKIKGLYLAGQINGTTGYEEAAAQGLMAGINAVLALKNQDPFIL
KRNEAYIGVLIDDLVTKGTNEPYRMFTSRAEYRLLLREDNTLFRLGEHAYRLGLMEEDFYKGLKKDQQEIQDNLKRLKEC
VLTPSKEVLKRLNELDENPINDKVDGVSLLARDSFNLEKMRSFFSFLTPLNERVLEQIKIECKYNIYIEKQHENIAKMDS
MLKVSIPKGFVFKGIPGLSLEAVEKLEKFRPKSLFEASEISGITPANLDVLHLYIHLRKNS
>Mature_621_residues
MVKESDILVIGGGHAGIEASLIAAKMGARVHLITMLIDTIGLASCNPAIGGLGKGHLTKEVDVLGGAMGIITDNSGLQYR
VLNASKGPAVRGTRAQIDMDTYRIFARNLVLNTPNLSVSQEMTESLIIENDEMVGVTTNINNTYKAKKVIITTGTFLKGV
VHIGEHQNQNGRFGENASNSLALNLRELGFRVERLKTGTCPRVAGNSIDFEGLEEHFGDTNPPYFSYKTKDFNPTQLSCF
ITYTNPITHQIIRDNFHRAPLFSGQIEGIGPRYCPSIEDKINRFSEKERHQLFLEPQTIHKSEYYINGLSTSLPLDVQEK
VIHSIKGLENALITRYGYAIEYDFIQPTELTHTLETKKIKGLYLAGQINGTTGYEEAAAQGLMAGINAVLALKNQDPFIL
KRNEAYIGVLIDDLVTKGTNEPYRMFTSRAEYRLLLREDNTLFRLGEHAYRLGLMEEDFYKGLKKDQQEIQDNLKRLKEC
VLTPSKEVLKRLNELDENPINDKVDGVSLLARDSFNLEKMRSFFSFLTPLNERVLEQIKIECKYNIYIEKQHENIAKMDS
MLKVSIPKGFVFKGIPGLSLEAVEKLEKFRPKSLFEASEISGITPANLDVLHLYIHLRKNS

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 [H]

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family [H]

Homologues:

Organism=Homo sapiens, GI74024895, Length=628, Percent_Identity=42.3566878980892, Blast_Score=430, Evalue=1e-120,
Organism=Homo sapiens, GI19882217, Length=653, Percent_Identity=41.04134762634, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI183227703, Length=668, Percent_Identity=39.8203592814371, Blast_Score=409, Evalue=1e-114,
Organism=Escherichia coli, GI2367273, Length=612, Percent_Identity=48.3660130718954, Blast_Score=594, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI17534255, Length=619, Percent_Identity=39.5799676898223, Blast_Score=423, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321202, Length=623, Percent_Identity=39.9678972712681, Blast_Score=432, Evalue=1e-122,
Organism=Drosophila melanogaster, GI24658174, Length=629, Percent_Identity=41.6534181240064, Blast_Score=447, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595 [H]

Pfam domain/function: PF01134 GIDA [H]

EC number: NA

Molecular weight: Translated: 69711; Mature: 69711

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS01280 GIDA_1 ; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKESDILVIGGGHAGIEASLIAAKMGARVHLITMLIDTIGLASCNPAIGGLGKGHLTKE
CCCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
VDVLGGAMGIITDNSGLQYRVLNASKGPAVRGTRAQIDMDTYRIFARNLVLNTPNLSVSQ
HHHHCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHEEECCCCCHHH
EMTESLIIENDEMVGVTTNINNTYKAKKVIITTGTFLKGVVHIGEHQNQNGRFGENASNS
HHHHHHEECCCCEEEEEECCCCCEEEEEEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCE
LALNLRELGFRVERLKTGTCPRVAGNSIDFEGLEEHFGDTNPPYFSYKTKDFNPTQLSCF
EEEEHHHHCCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCCCCEEEEE
ITYTNPITHQIIRDNFHRAPLFSGQIEGIGPRYCPSIEDKINRFSEKERHQLFLEPQTIH
EEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHEEEECCHHHC
KSEYYINGLSTSLPLDVQEKVIHSIKGLENALITRYGYAIEYDFIQPTELTHTLETKKIK
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHEEC
GLYLAGQINGTTGYEEAAAQGLMAGINAVLALKNQDPFILKRNEAYIGVLIDDLVTKGTN
EEEEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCEEEEEHHHHHHCCCC
EPYRMFTSRAEYRLLLREDNTLFRLGEHAYRLGLMEEDFYKGLKKDQQEIQDNLKRLKEC
CHHHHHHCCCCEEEEEECCCCEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLTPSKEVLKRLNELDENPINDKVDGVSLLARDSFNLEKMRSFFSFLTPLNERVLEQIKI
HCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHEEE
ECKYNIYIEKQHENIAKMDSMLKVSIPKGFVFKGIPGLSLEAVEKLEKFRPKSLFEASEI
EEEEEEEEEECCCCHHHHHCEEEEECCCCEEECCCCCCCHHHHHHHHHCCCHHHCCHHHC
SGITPANLDVLHLYIHLRKNS
CCCCCCCCEEEEEEEEEECCC
>Mature Secondary Structure
MVKESDILVIGGGHAGIEASLIAAKMGARVHLITMLIDTIGLASCNPAIGGLGKGHLTKE
CCCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
VDVLGGAMGIITDNSGLQYRVLNASKGPAVRGTRAQIDMDTYRIFARNLVLNTPNLSVSQ
HHHHCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHEEECCCCCHHH
EMTESLIIENDEMVGVTTNINNTYKAKKVIITTGTFLKGVVHIGEHQNQNGRFGENASNS
HHHHHHEECCCCEEEEEECCCCCEEEEEEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCE
LALNLRELGFRVERLKTGTCPRVAGNSIDFEGLEEHFGDTNPPYFSYKTKDFNPTQLSCF
EEEEHHHHCCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCCCCEEEEE
ITYTNPITHQIIRDNFHRAPLFSGQIEGIGPRYCPSIEDKINRFSEKERHQLFLEPQTIH
EEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHEEEECCHHHC
KSEYYINGLSTSLPLDVQEKVIHSIKGLENALITRYGYAIEYDFIQPTELTHTLETKKIK
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHEEC
GLYLAGQINGTTGYEEAAAQGLMAGINAVLALKNQDPFILKRNEAYIGVLIDDLVTKGTN
EEEEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCEEEEEHHHHHHCCCC
EPYRMFTSRAEYRLLLREDNTLFRLGEHAYRLGLMEEDFYKGLKKDQQEIQDNLKRLKEC
CHHHHHHCCCCEEEEEECCCCEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLTPSKEVLKRLNELDENPINDKVDGVSLLARDSFNLEKMRSFFSFLTPLNERVLEQIKI
HCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHEEE
ECKYNIYIEKQHENIAKMDSMLKVSIPKGFVFKGIPGLSLEAVEKLEKFRPKSLFEASEI
EEEEEEEEEECCCCHHHHHCEEEEECCCCEEECCCCCCCHHHHHHHHHCCCHHHCCHHHC
SGITPANLDVLHLYIHLRKNS
CCCCCCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA