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The map label for this gene is 188526983

Identifier: 188526983

GI number: 188526983

Start: 169636

End: 170658

Strand: Reverse

Name: 188526983

Synonym: HPSH_00900

Alternate gene names: NA

Gene position: 170658-169636 (Counterclockwise)

Preceding gene: 188526984

Following gene: 188526978

Centisome position: 10.61

GC content: 39.78

Gene sequence:

>1023_bases
ATGTTACAACGCCCTAAAATTGTCGCTGAATTGAGCGCTAATCATAACCAGGATTTAAATCTCGCCAAAGAAAGCCTTCA
TGCCATTAAGGAAAGCGGCGCGGATTTTGTCAAGCTCCAAACCTACACGCCAAGCTGCATGACTTTAAACTCTAAAGAAG
ATCCTTTCATCATTCAAGGCACTTTATGGGATAAAGAAAATTTGTATGAATTGTATCAAAAGGCTTCCACCCCCCTAGAA
TGGCATGCGGAATTGTTTGAATTGGCTAAAAAGCTTGATTTAGGCATTTTTAGCTCGCCTTTTAGCTCAAAAGCTTTAGA
ACTTTTAGAGAGCCTGAATTGCCCCATGTATAAAATCGCTAGTTTTGAAATCGTTGATTTAGACTTGATTGAAAAAGCCG
CTCGCACAAAAAAGCCCATTATCCTTTCTAGCGGTATCGCTACACACACCGAATTGCAAGACGCTATCTCATTGTGTAGA
GAAGTGGGTAATTTTGACATCACCCTTTTAAAATGCGTGAGCGCTTATCCTAGCCAAATAGAAGACGCTAATTTATTGAA
CATGGTTAAATTAGGCGAAACCTTTGGCGTTAAATTTGGCTTGAGCGATCACACGATTGGCTCTCTTTGCCCCATTCTAG
CCACCACTTTAGGAGCGAGCATGATAGAAAAGCATTTCATTTTAAACAAATCCTTACAAACCCCAGACAGCGCTTTTAGC
ATGGATTTTAACGGATTTAAAAGCATGGTTGAAGCCATCAAACAAAGCGTTTTAGCCTTAGGCGAAGAAGAGCCTAAAAT
CAATCCAAAGACTTTAGAAGAGCGGAGATTCTTTATGCGCTCTTTATTTGTCATTAAGGATATTCAAAAAGGCGAAGCAT
TGACTAGCGATAATATCAAAGCCTTACGCCCCAACCTTGGCTTACACCCTAAATTTTATAAAGAAATTTTAGGCCAAAAG
GCATCAAAATTCTTAAAAGCCAACACCCCTTTAAGCGCTGATGGTATAGAACGCTCATTGTAG

Upstream 100 bases:

>100_bases
AGGGGCGTTAGTTCTAGCCACGCATGATGAGCATTTGGCTTTCACTTGCTCTCAAGTCTATCGCTTAGAAAAAGAAATTT
TGATTAAGGAAAAATAAGAG

Downstream 100 bases:

>100_bases
GTTTGATTAAAAAATGGGGGTTTTAAATTTTGTTTTGTGGTTTTAGATTTGATTTTAGACTCATTTTCTTTATTTTAAGC
TCTTAAGGGGATAGGGGCAT

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLQRPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYELYQKASTPLE
WHAELFELAKKLDLGIFSSPFSSKALELLESLNCPMYKIASFEIVDLDLIEKAARTKKPIILSSGIATHTELQDAISLCR
EVGNFDITLLKCVSAYPSQIEDANLLNMVKLGETFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
MDFNGFKSMVEAIKQSVLALGEEEPKINPKTLEERRFFMRSLFVIKDIQKGEALTSDNIKALRPNLGLHPKFYKEILGQK
ASKFLKANTPLSADGIERSL

Sequences:

>Translated_340_residues
MLQRPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYELYQKASTPLE
WHAELFELAKKLDLGIFSSPFSSKALELLESLNCPMYKIASFEIVDLDLIEKAARTKKPIILSSGIATHTELQDAISLCR
EVGNFDITLLKCVSAYPSQIEDANLLNMVKLGETFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
MDFNGFKSMVEAIKQSVLALGEEEPKINPKTLEERRFFMRSLFVIKDIQKGEALTSDNIKALRPNLGLHPKFYKEILGQK
ASKFLKANTPLSADGIERSL
>Mature_340_residues
MLQRPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQGTLWDKENLYELYQKASTPLE
WHAELFELAKKLDLGIFSSPFSSKALELLESLNCPMYKIASFEIVDLDLIEKAARTKKPIILSSGIATHTELQDAISLCR
EVGNFDITLLKCVSAYPSQIEDANLLNMVKLGETFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
MDFNGFKSMVEAIKQSVLALGEEEPKINPKTLEERRFFMRSLFVIKDIQKGEALTSDNIKALRPNLGLHPKFYKEILGQK
ASKFLKANTPLSADGIERSL

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=324, Percent_Identity=28.0864197530864, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21357081, Length=360, Percent_Identity=26.3888888888889, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 37903; Mature: 37903

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQRPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQG
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEEE
TLWDKENLYELYQKASTPLEWHAELFELAKKLDLGIFSSPFSSKALELLESLNCPMYKIA
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEC
SFEIVDLDLIEKAARTKKPIILSSGIATHTELQDAISLCREVGNFDITLLKCVSAYPSQI
CEEEEHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
EDANLLNMVKLGETFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
CCCHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
MDFNGFKSMVEAIKQSVLALGEEEPKINPKTLEERRFFMRSLFVIKDIQKGEALTSDNIK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALRPNLGLHPKFYKEILGQKASKFLKANTPLSADGIERSL
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLQRPKIVAELSANHNQDLNLAKESLHAIKESGADFVKLQTYTPSCMTLNSKEDPFIIQG
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEEE
TLWDKENLYELYQKASTPLEWHAELFELAKKLDLGIFSSPFSSKALELLESLNCPMYKIA
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEC
SFEIVDLDLIEKAARTKKPIILSSGIATHTELQDAISLCREVGNFDITLLKCVSAYPSQI
CEEEEHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
EDANLLNMVKLGETFGVKFGLSDHTIGSLCPILATTLGASMIEKHFILNKSLQTPDSAFS
CCCHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
MDFNGFKSMVEAIKQSVLALGEEEPKINPKTLEERRFFMRSLFVIKDIQKGEALTSDNIK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALRPNLGLHPKFYKEILGQKASKFLKANTPLSADGIERSL
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]