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The map label for this gene is arlR [H]

Identifier: 188526970

GI number: 188526970

Start: 158624

End: 159301

Strand: Reverse

Name: arlR [H]

Synonym: HPSH_00835

Alternate gene names: 188526970

Gene position: 159301-158624 (Counterclockwise)

Preceding gene: 188526971

Following gene: 188526969

Centisome position: 9.9

GC content: 38.2

Gene sequence:

>678_bases
ATGATAGAAGTTTTAATGATAGAAGATGATATAGAATTAGCCGAGTTTTTGAGCGAGTTTTTGCTCCAGCATGGCATTCA
TGTAACCAATTACGATGAGCCATATACCGGCATTAGTGCGGCTAACACACAAAATTATGATTTGTTGTTATTGGATTTAA
CTTTGCCTAATTTAGACGGGCTTGAAGTGTGTAGGCGCATCTCCAAACAAAAACATATCCCTATTATTATTTCTTCAGCA
AGAAGCGATGTGGAAGATAAGATTAAAGCGCTAGATTATGGGGCTGATGATTACCTCCCTAAACCCTATGATCCTAAAGA
ATTATTAGCTCGCATCCAGTCCTTACTCAGGCGTTCTCATAAAAAAGAAGAAGTGAGTGAGCCAAGCGATGCGAATATCT
TTAGGGTAGATAAGGACAGCCGAGAAGTGTATATGCATGAAAAAAAGCTAGACTTAACTAGGGCTGAATATGAAATCCTT
TCGCTTCTCATTAGCAAAAAAGGTTATGTGTTTAGCCGTGAAAGCATTGCGATTGAGAGCGAGAGCATCAACCCTGAAAG
CTCTAATAAAAGCATTGATGTGATCATTGGCCGTTTGCGATCCAAGATTGAAAAAAATCCTAAACAACCGCAATATATCA
TCTCTGTTAGAGGGATTGGTTATAAATTAGAATACTGA

Upstream 100 bases:

>100_bases
GGTATCTTTAATAATAAAATGCTAGAATTAGTCCCTTAAAACATTAACAAAGTTAATCGTTTTTAAAGTTGCAAAAATCA
TTGAAGGAGTTAATTGAAGT

Downstream 100 bases:

>100_bases
CATTCTAATAAGGAGTTAAGGGGTTTTGCGTTTTTCTATCTTTTTTAAAGTTGTCGCTTTGTTTATGATAACGCTCTTTA
GTTTTGGAGCGTTCGCTTAC

Product: response regulator (ompR)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MIEVLMIEDDIELAEFLSEFLLQHGIHVTNYDEPYTGISAANTQNYDLLLLDLTLPNLDGLEVCRRISKQKHIPIIISSA
RSDVEDKIKALDYGADDYLPKPYDPKELLARIQSLLRRSHKKEEVSEPSDANIFRVDKDSREVYMHEKKLDLTRAEYEIL
SLLISKKGYVFSRESIAIESESINPESSNKSIDVIIGRLRSKIEKNPKQPQYIISVRGIGYKLEY

Sequences:

>Translated_225_residues
MIEVLMIEDDIELAEFLSEFLLQHGIHVTNYDEPYTGISAANTQNYDLLLLDLTLPNLDGLEVCRRISKQKHIPIIISSA
RSDVEDKIKALDYGADDYLPKPYDPKELLARIQSLLRRSHKKEEVSEPSDANIFRVDKDSREVYMHEKKLDLTRAEYEIL
SLLISKKGYVFSRESIAIESESINPESSNKSIDVIIGRLRSKIEKNPKQPQYIISVRGIGYKLEY
>Mature_225_residues
MIEVLMIEDDIELAEFLSEFLLQHGIHVTNYDEPYTGISAANTQNYDLLLLDLTLPNLDGLEVCRRISKQKHIPIIISSA
RSDVEDKIKALDYGADDYLPKPYDPKELLARIQSLLRRSHKKEEVSEPSDANIFRVDKDSREVYMHEKKLDLTRAEYEIL
SLLISKKGYVFSRESIAIESESINPESSNKSIDVIIGRLRSKIEKNPKQPQYIISVRGIGYKLEY

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=36.6071428571429, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=34.070796460177, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=34.2342342342342, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=34.8017621145374, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=32.6086956521739, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=29.8642533936652, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=29.1479820627803, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=33.6283185840708, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=35.8744394618834, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=30.4932735426009, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=29.5154185022026, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=29.646017699115, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=29.7872340425532, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1790863, Length=184, Percent_Identity=28.2608695652174, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=31.6666666666667, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25886; Mature: 25886

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVLMIEDDIELAEFLSEFLLQHGIHVTNYDEPYTGISAANTQNYDLLLLDLTLPNLDG
CEEEEEECCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCH
LEVCRRISKQKHIPIIISSARSDVEDKIKALDYGADDYLPKPYDPKELLARIQSLLRRSH
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KKEEVSEPSDANIFRVDKDSREVYMHEKKLDLTRAEYEILSLLISKKGYVFSRESIAIES
HHHHCCCCCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEC
ESINPESSNKSIDVIIGRLRSKIEKNPKQPQYIISVRGIGYKLEY
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECC
>Mature Secondary Structure
MIEVLMIEDDIELAEFLSEFLLQHGIHVTNYDEPYTGISAANTQNYDLLLLDLTLPNLDG
CEEEEEECCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCH
LEVCRRISKQKHIPIIISSARSDVEDKIKALDYGADDYLPKPYDPKELLARIQSLLRRSH
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KKEEVSEPSDANIFRVDKDSREVYMHEKKLDLTRAEYEILSLLISKKGYVFSRESIAIES
HHHHCCCCCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEC
ESINPESSNKSIDVIIGRLRSKIEKNPKQPQYIISVRGIGYKLEY
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA